Page last updated: 2024-08-22

n-methylaspartate and alpha-aminopyridine

n-methylaspartate has been researched along with alpha-aminopyridine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's5 (45.45)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haberly, LB; Hoffman, WH1
de Carolis, AS; Frank, C; Sagratella, S1
Iskric, S; Müller, WE; Pergande, G; Perovic, S; Rytik, P; Schleger, C; Ushijima, H1
Block, F; Pergande, G; Schwarz, M1
Kelve, M; Müller, WE; Pergande, G; Perovic, S; Schleger, C; Ushijima, H1
Müller, WE; Pergande, G; Perovic, S; Pialoglou, P; Schröder, HC1
Jakob, R; Krieglstein, J1
Melena, J; Nash, MS; Osborne, NN; Wood, JP1
Bechmann, I; Deisz, R; Dörr, J; Lehmann, TN; Meier, S; Nitsch, R; Roth, K; Zipp, F; Zurbuchen, U1
Annunziato, L; Boscia, F; Taglialatela, M1
Eto, K; Kashiwagi, K; Koizumi, S; Nabekura, J; Ohno, N; Shinozaki, Y; Takeda, A; Wake, H1

Other Studies

11 other study(ies) available for n-methylaspartate and alpha-aminopyridine

ArticleYear
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine

1989
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine

1987
The triaminopyridine flupirtine prevents cell death in rat cortical cells induced by N-methyl-D-aspartate and gp120 of HIV-1.
    European journal of pharmacology, 1994, Dec-15, Volume: 288, Issue:1

    Topics: AIDS Dementia Complex; Aminopyridines; Analgesics; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; HIV Envelope Protein gp120; HIV-1; Molecular Weight; N-Methylaspartate; Neurons; Rats; Rats, Wistar

1994
N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of flupirtine in rats.
    Neuroreport, 1994, Oct-03, Volume: 5, Issue:15

    Topics: Aminopyridines; Analgesics; Animals; Dose-Response Relationship, Drug; H-Reflex; Injections, Intraperitoneal; Injections, Spinal; Male; Muscle Relaxants, Central; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex

1994
Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention.
    Progress in molecular and subcellular biology, 1996, Volume: 16

    Topics: Aminopyridines; Animals; Apoptosis; Arachidonic Acid; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; HIV Envelope Protein gp120; HIV-1; Memantine; Models, Biological; N-Methylaspartate; Neurons; Neuroprotective Agents; Phospholipases A; Phospholipases A2; Rats

1996
Flupirtine increases the levels of glutathione and Bc1-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect.
    European journal of pharmacology, 1996, Dec-12, Volume: 317, Issue:1

    Topics: Aminopyridines; Analgesics, Non-Narcotic; Apoptosis; Cell Line; DNA Fragmentation; Excitatory Amino Acid Agonists; Glutamic Acid; Glutathione; Humans; Immunohistochemistry; N-Methylaspartate; Neurons; Proto-Oncogene Proteins c-bcl-2

1996
Influence of flupirtine on a G-protein coupled inwardly rectifying potassium current in hippocampal neurones.
    British journal of pharmacology, 1997, Volume: 122, Issue:7

    Topics: Aminopyridines; Animals; Barium Compounds; Cell Culture Techniques; Chlorides; Cyclic AMP; Excitatory Amino Acid Agonists; GTP-Binding Proteins; Hippocampus; Membrane Potentials; Muscle Relaxants, Central; N-Methylaspartate; Neurons; Pertussis Toxin; Potassium; Rats; Virulence Factors, Bordetella

1997
Flupirtine ameliorates ischaemic-like death of rat retinal ganglion cells by preventing calcium influx.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Aminopyridines; Animals; Biological Transport; Calcium; Cell Death; Cerebral Cortex; Fetus; Ischemia; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Retinal Ganglion Cells; Retinal Vessels; RNA, Messenger; Thy-1 Antigens; Transcription, Genetic

2000
Tumor-necrosis-factor-related apoptosis-inducing-ligand (TRAIL)-mediated death of neurons in living human brain tissue is inhibited by flupirtine-maleate.
    Journal of neuroimmunology, 2005, Volume: 167, Issue:1-2

    Topics: Aminopyridines; Apoptosis Regulatory Proteins; Cell Count; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Membrane Glycoproteins; N-Methylaspartate; Neocortex; Neurons; Neuroprotective Agents; Propidium; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2005
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures.
    Neuropharmacology, 2006, Volume: 51, Issue:2

    Topics: Aminopyridines; Animals; Carbamates; Culture Media, Serum-Free; Glucose; Hippocampus; KCNQ Potassium Channels; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Oxygen; Phenylenediamines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Tissue Culture Techniques

2006
Microglia mediate non-cell-autonomous cell death of retinal ganglion cells.
    Glia, 2018, Volume: 66, Issue:11

    Topics: Aminopyridines; Animals; Animals, Newborn; Calcium-Binding Proteins; Cell Death; Cells, Cultured; Cytokines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microglia; N-Methylaspartate; Nerve Degeneration; Optic Nerve Injuries; Organic Chemicals; Pyrroles; Retinal Ganglion Cells; Signal Transduction; Transcription Factor Brn-3A; Tumor Necrosis Factor-alpha

2018