n-methylaspartate has been researched along with adenosine in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.11) | 18.7374 |
| 1990's | 52 (54.74) | 18.2507 |
| 2000's | 25 (26.32) | 29.6817 |
| 2010's | 13 (13.68) | 24.3611 |
| 2020's | 3 (3.16) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Craig, CG; White, TD | 4 |
| Chen, Y; Graham, DI; Stone, TW | 1 |
| Connick, JH; Mally, J; Stone, TW | 3 |
| Chernevskaya, NI; Krishtal, OA; Obukhov, AG | 1 |
| Porsche, E; Schwan, T | 1 |
| Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Mally, J; Stone, TW | 1 |
| Hoehn, K; White, TD | 2 |
| Craig, CG; Hoehn, K; White, TD | 1 |
| Choi, DW | 1 |
| DeLander, GE; Wahl, JJ | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Beenhakker, M; Carter, MF; Daly, JW; Jacobson, KA; Kim, J; Lin, RC; Meshulam, Y; Shi, D; Von Lubitz, DK; Zhou, LM | 1 |
| Jahr, CE; Tong, G | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Craig, CG; Temple, SD; White, TD | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Northington, FJ; Stiefel, T; Traystman, RJ | 1 |
| Gordh, T; Karlsten, R; Kristensen, J | 1 |
| Bickler, PE; Buck, LT | 1 |
| Carter, MF; Deutsch, SI; Jacobson, KA; Lin, RC; Mastropaolo, J; Meshulam, Y; Von Lubitz, DK | 1 |
| Ferré, S; Giménez-Llort, L; Martínez, E | 1 |
| Manabe, T; Manzoni, OJ; Nicoll, RA | 1 |
| Asztely, F; Gustafsson, B; Wigström, H; Xiao, MY | 1 |
| Carter, M; Jacobson, KA; Ji, XD; Paul, IA; Von Lubitz, DK | 1 |
| Choi, DW; Lobner, D | 1 |
| Sheardown, MJ | 1 |
| Carter, M; Jacobson, KA; Paul, IA; Von Lubitz, DK | 1 |
| During, MJ; Kaiser, MG | 1 |
| White, TD | 1 |
| Dale, N; Gilday, D | 1 |
| Delaney, SM; Geiger, JD | 2 |
| Bong, GW; Firestein, GS; Rosengren, S | 1 |
| Semba, K; White, TD | 2 |
| Illes, P; Nörenberg, W; Wirkner, K | 1 |
| Bari, F; Busija, DW; Louis, TM; Thore, CR | 1 |
| Wang, Y; White, TD | 1 |
| Delaney, SM; Geiger, JD; Shepel, PN | 1 |
| Hebb, MO; White, TD | 1 |
| Dora, CD; Koch, S; Liu, S; Ruenes, G; Sanchez, A; Yezierski, RP | 1 |
| Bari, F; Busija, DW; Louis, TM | 1 |
| Kato, K; Li, ST; Zorumski, CF | 1 |
| Johnson, SW; Shen, KZ; Wu, YN | 1 |
| Daisley, JN; Rose, SP | 1 |
| Corsi, C; Ferré, S; Giménez-Llort, L; Martínez, E; Melani, A; Ogren, SO; Pedata, F | 1 |
| Hsu, KS; Huang, CC; Liang, YC | 1 |
| Müller, T | 1 |
| Haller, M; Mironov, SL; Richter, DW | 1 |
| Nikbakht, MR; Stone, TW | 1 |
| Bon, CL; Garthwaite, J | 1 |
| O'Donnell, JM; Suvarna, NU | 1 |
| Buño, W; Cabezas, C; de Prada, AN; Fernández de Sevilla, D; Sánchez-Jiménez, A | 1 |
| Lobner, D | 1 |
| Laube, B; Ortinau, S; Zimmermann, H | 1 |
| Aizenman, E; Epstein, PM; Herin, GA; Li, Y; Lu, Y; Rosenberg, PA | 1 |
| Domenici, MR; Frank, C; Grieco, R; Martire, A; Pepponi, R; Pintor, A; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Shahraki, A; Stone, TW | 1 |
| Domenici, MR; Martire, A; Pepponi, R; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Borycz, J; Ciruela, F; Ferré, S; Franco, R; Goldberg, SR; Hockemeyer, J; Lluis, C; Patkar, K; Quarta, D; Solinas, M; Woods, AS | 1 |
| Goto, W; Hara, H; Hirao, M; Ikeda, T; Kobayashi, T; Oku, H; Okuno, T; Sugiyama, T; Yoneda, S | 1 |
| Brambilla, D; Chapman, D; Greene, R | 1 |
| An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
| Chen, JF; Cunha, RA; Domenici, MR; Grò, MC; Martire, A; Pepponi, R; Popoli, P; Rebola, N; Schwarzschild, MA; Tebano, MT | 1 |
| Bose, R; Parkinson, FE; Zamzow, CR | 2 |
| Cunha, RA; Lujan, R; Mulle, C; Rebola, N | 1 |
| Aalkjaer, C; Bek, T; Holmgaard, K; Lambert, JD | 1 |
| Azdad, K; d'Exaerde, Ade K; Dumont, H; Gall, D; Guntz, E; Pastijn, E; Schiffmann, SN; Sosnowski, M | 1 |
| Parkinson, FE; Xiong, W; Zamzow, CR | 1 |
| Bek, T; Holmgaard, K | 1 |
| Delgado, A; Martínez-Romero, B; Miranda, JE; Querejeta, E | 1 |
| Agostinho, PM; Canas, PM; Costenla, AR; Cunha, RA; de Mendonça, A; Diógenes, MJ; Maroco, J; Nogueira, C; Ribeiro, JA; Rodrigues, RJ | 1 |
| Day, M; Plotkin, JL; Surmeier, DJ | 1 |
| Cho, GS; Choi, IY; Choi, WJ; Hwang, S; Jeong, LS; Ju, C; Kim, WK; Lee, HW; Lee, JC | 1 |
| Illes, P; Leichsenring, A; Nörenberg, W; Pesic, M; Servettini, I; Sperlagh, B; Tautenhahn, M | 1 |
| Kaster, MP; Machado, DG; Rodrigues, AL; Santos, AR | 1 |
| Atas, HC; Biber, K; Normann, C; Serchov, T; van Calker, D | 1 |
| Crawford, DC; Jiang, X; Mennerick, S; Taylor, A | 1 |
| Dale, N; Wall, MJ | 1 |
| Nagaoka, T; Nakabayashi, S; Tani, T; Yoshida, A; Yoshioka, T | 1 |
| Boeck, CR; Ciruela, F; Constantino, LC; Gomez-Soler, M; Ludka, FK; Matheus, FC; Pamplona, FA; Prediger, RD; Tasca, CI | 1 |
| Ambrósio, AF; Cordeiro, MF; Elvas, F; Galvao, J; Martins, T; Santiago, AR | 1 |
| Cheng, L; Hou, C; Xiao, L; Yan, N; Zhao, L; Zheng, S | 1 |
| Fisone, G; Gangarossa, G; Onimus, O; Valjent, E | 1 |
| Gonçalves, J; Queiroz, G; Quintas, C | 1 |
3 review(s) available for n-methylaspartate and adenosine
| Article | Year |
|---|---|
Possible mechanisms limiting N-methyl-D-aspartate receptor overactivation and the therapeutic efficacy of N-methyl-D-aspartate antagonists.
Topics: Adenosine; Animals; Brain Ischemia; Calcium; Glutamates; Hydrogen-Ion Concentration; Hypoxia; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Zinc | 1990 |
Intervention with spinal NMDA, adenosine, and NO systems for pain modulation.
Topics: Adenosine; Analgesics; Animals; Humans; Injections, Spinal; N-Methylaspartate; Nitric Oxide; Pain, Postoperative; Spinal Cord | 1995 |
Non-dopaminergic drug treatment of Parkinson's disease.
Topics: Adenosine; Adrenergic alpha-Antagonists; Body Weight; Cholinergic Antagonists; Homocysteine; Humans; Levodopa; Methionine; N-Methylaspartate; Parkinson Disease; Piperidines; Serotonin Receptor Agonists | 2001 |
1 trial(s) available for n-methylaspartate and adenosine
| Article | Year |
|---|---|
The effect of theophylline on essential tremor: the possible role of GABA.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Animals; Cerebral Cortex; Delayed-Action Preparations; Double-Blind Method; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Isoproterenol; Male; Mice; Middle Aged; N-Methylaspartate; Propranolol; Serotonin; Theophylline; Tremor | 1991 |
91 other study(ies) available for n-methylaspartate and adenosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotransformation; Cerebral Cortex; Cyclic AMP; Cycloleucine; Female; Guinea Pigs; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Male; N-Methylaspartate; Receptors, Amino Acid; Receptors, Purinergic; Vasodilator Agents | 1992 |
Adenosine-dependent enhancement by methylxanthines of excitatory synaptic transmission in hippocampus of rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Theophylline | 1992 |
Low-level N-methyl-D-aspartate receptor activation provides a purinergic inhibitory threshold against further N-methyl-D-aspartate-mediated neurotransmission in the cortex.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Male; N-Methylaspartate; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Release of endogenous adenosine and its metabolites by the activation of NMDA receptors in the rat hippocampus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Calcium; Hippocampus; Male; N-Methylaspartate; Perfusion; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Veratridine | 1992 |
Changes in neurotransmitter sensitivity in the mouse neocortical slice following propranolol and theophylline administration.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Isoproterenol; Male; Mice; N-Methylaspartate; Propranolol; Serotonin; Theophylline | 1991 |
NMDA receptor agonists selectively block N-type calcium channels in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Aspartic Acid; Calcium; Calcium Channels; Glutamates; Hippocampus; Kynurenic Acid; Mollusk Venoms; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1991 |
Depression of NMDA-evoked acetylcholine release by endogenous adenosine in striatum slices.
Topics: Acetylcholine; Adenosine; Animals; Corpus Striatum; Female; Hypoxia; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains | 1991 |
Endogenous adenosine release from hippocampal slices: excitatory amino acid agonists stimulate release, antagonists reduce the electrically-evoked release.
Topics: Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Hippocampus; Inosine; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Endogenous glycine modulates N-methyl-D-aspartate-evoked release of adenosine and [3H]noradrenaline from rat cortical slices.
Topics: Adenosine; Animals; Cerebral Cortex; Glycine; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Strychnine | 1991 |
Role of excitatory amino acid receptors in K+- and glutamate-evoked release of endogenous adenosine from rat cortical slices.
Topics: Adenosine; Animals; Aspartic Acid; Calcium; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; N-Methylaspartate; Potassium; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1990 |
Chronic benzodiazepine treatment and cortical responses to adenosine and GABA.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Cerebral Cortex; Clonazepam; Diazepam; Electrodes; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; N-Methylaspartate; Serotonin; Theophylline | 1990 |
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Animals; Calcium; Cerebral Cortex; Dipeptides; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
A comparison of N-methyl-D-aspartate-evoked release of adenosine and [3H]norepinephrine from rat cortical slices.
Topics: Adenosine; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1990 |
Theophylline down-regulates adenosine receptor function.
Topics: Adenosine; Animals; Aspartic Acid; Isoproterenol; Male; Mice; N-Methylaspartate; Receptors, Purinergic; Serotonin; Theophylline | 1990 |
Behavior induced by putative nociceptive neurotransmitters is inhibited by adenosine or adenosine analogs coadministered intrathecally.
Topics: Adenosine; Animals; Aspartic Acid; Behavior, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Spinal; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Pain; Substance P | 1988 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Chronic NMDA receptor stimulation: therapeutic implications of its effect on adenosine A1 receptors.
Topics: Adenosine; Animals; Cerebral Cortex; Hippocampus; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pentostatin; Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Seizures | 1995 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Ionotropic glutamate receptor types leading to adenosine-mediated inhibition of electrically evoked [3H]-noradrenaline release in rabbit brain cortex slices.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Female; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rabbits; Receptors, Glutamate | 1993 |
Is cyclic AMP involved in excitatory amino acid-evoked adenosine release from rat cortical slices?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Excitatory Amino Acids; Male; N-Methylaspartate; Parietal Lobe; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Radioisotopes; Citrulline; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1995 |
Role of adenosine in NMDA receptor modulation in the cerebral cortex of an anoxia-tolerant turtle (Chrysemys picta belli).
Topics: Adenosine; Animals; Calcium; Cerebral Cortex; Female; Fluorometry; Fura-2; Glutamates; Hypoxia, Brain; Male; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Theophylline; Turtles | 1995 |
N-methyl-D-aspartate- and non-N-methyl-D-aspartate-evoked adenosine release from rat cortical slices: distinct purinergic sources and mechanisms of release.
Topics: 5'-Nucleotidase; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Nucleosides; Purines; Rats | 1993 |
The effects of adenosine A3 receptor stimulation on seizures in mice.
Topics: Adenosine; Animals; Clonidine; Drug Interactions; Electroshock; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; p-Methoxy-N-methylphenethylamine; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Seizures | 1995 |
Dopamine-independent and adenosine-dependent mechanisms involved in the effects of N-methyl-D-aspartate on motor activity in mice.
Topics: Adenosine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Motor Activity; N-Methylaspartate; Reserpine; Theophylline | 1995 |
Release of adenosine by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Enkephalins; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Theophylline | 1994 |
Effect of adenosine-induced changes in presynaptic release probability on long-term potentiation in the hippocampal CA1 region.
Topics: Adenosine; Animals; Calcium; Electric Stimulation; Electrophysiology; Guinea Pigs; Hippocampus; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurotransmitter Agents; Presynaptic Terminals; Probability; Reaction Time; Xanthines | 1994 |
Chronic adenosine A1 receptor agonist and antagonist: effect on receptor density and N-methyl-D-aspartate induced seizures in mice.
Topics: Adenosine; Animals; Binding Sites; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Receptors, Purinergic P1; Seizures; Xanthines | 1994 |
Dipyridamole increases oxygen-glucose deprivation-induced injury in cortical cell culture.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dipyridamole; Glucose; Glutamates; Hypoxia, Brain; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Theophylline | 1994 |
The triggering of spreading depression in the chicken retina: a pharmacological study.
Topics: Adenosine; Amino Acids; Animals; Baclofen; Calcium Channel Blockers; Chickens; Depression, Chemical; Excitatory Amino Acid Antagonists; Eye Enucleation; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Retina | 1993 |
NMDA-evoked adenosine release from rat cortex does not require the intermediate formation of nitric oxide.
Topics: Adenosine; Animals; Arginine; Cerebral Cortex; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley | 1993 |
Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice.
Topics: Adenosine; Animals; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Seizures; Survival Rate; Temperature; Xanthines | 1993 |
Combining laser Doppler flowmetry with microdialysis: a novel approach to investigate the coupling of regional cerebral blood flow to neuronal activity.
Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Citrulline; Excitatory Amino Acid Agonists; Hippocampus; Laser-Doppler Flowmetry; Male; Microdialysis; N-Methylaspartate; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 1995 |
Potentiation of excitatory amino acid-evoked adenosine release from rat cortex by inhibitors of adenosine kinase and adenosine deaminase and by acadesine.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoimidazole Carboxamide; Animals; Cerebral Cortex; Drug Synergism; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Ribonucleosides | 1996 |
Regulation of rhythmic movements by purinergic neurotransmitters in frog embryos.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Culture Techniques; Embryo, Nonmammalian; Glutamic Acid; Ion Channel Gating; Motor Neurons; Movement; N-Methylaspartate; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spinal Cord; Suramin; Swimming; Synapses; Theophylline; Xenopus | 1996 |
Enhancement of NMDA-induced increases in levels of endogenous adenosine by adenosine deaminase and adenosine transport inhibition in rat striatum.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1995 |
Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Inflammatory Agents; Carrageenan; Catheterization; Central Nervous System; Dexamethasone; Excitatory Amino Acid Antagonists; Inflammation; N-Methylaspartate; Neutrophils; Peroxidase; Phenethylamines; Propionates; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Skin; Spinal Cord; Theobromine | 1996 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Effect of adenosine and some of its structural analogues on the conductance of NMDA receptor channels in a subset of rat neostriatal neurones.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antihypertensive Agents; Carrier Proteins; Cell Membrane; Ion Channels; Membrane Potentials; Membrane Proteins; N-Methylaspartate; Neostriatum; Neural Conduction; Neurons; Nucleoside Transport Proteins; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1997 |
A comparison of (+/-)epibatidine with NMDA in releasing [3H]noradrenaline and adenosine from slices of rat hippocampus and parietal cortex.
Topics: Adenosine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Norepinephrine; Parietal Lobe; Pyridines; Rats; Rats, Wistar; Tritium | 1997 |
Inhibitory effects of hypoxia and adenosine on N-methyl-D-aspartate-induced pial arteriolar dilation in piglets.
Topics: Adenosine; Animals; Animals, Newborn; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Female; Hypoxia; Immunohistochemistry; Male; N-Methylaspartate; Nitric Oxide; Nitroprusside; Pia Mater; Receptors, N-Methyl-D-Aspartate; Swine; Theophylline; Vasodilator Agents | 1998 |
Effect of protein kinase C activation on N-methyl-D-aspartate-evoked release of adenosine and [3H]Norepinephrine from rat cortical slices.
Topics: Adenosine; Animals; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Indoles; Magnesium; Male; Maleimides; N-Methylaspartate; Norepinephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Levels of endogenous adenosine in rat striatum. I. Regulation by ionotropic glutamate receptors, nitric oxide and free radicals.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Corpus Striatum; Dizocilpine Maleate; Free Radicals; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1998 |
Levels of endogenous adenosine in rat striatum. II. Regulation of basal and N-methyl-D-aspartate-induced levels by inhibitors of adenosine transport and metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Corpus Striatum; Dilazep; Male; N-Methylaspartate; Pentostatin; Rats; Rats, Sprague-Dawley | 1998 |
Co-administration of adenosine kinase and deaminase inhibitors produces supra-additive potentiation of N-methyl-D-aspartate-evoked adenosine formation in cortex.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cerebral Cortex; Deoxyadenosines; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1998 |
Intraspinal injection of adenosine agonists protect against L-NAME induced neuronal loss in the rat.
Topics: Adenosine; Animals; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Injections, Spinal; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Rats; Rats, Long-Evans; Spinal Cord | 1998 |
Factors modulating N-methyl-D-aspartate (NMDA)-induced cerebral vasodilation after hypoxia/ischemia in piglets.
Topics: Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Hypoxia, Brain; Ischemic Attack, Transient; N-Methylaspartate; Nitroprusside; Pia Mater; Swine; Theophylline; Vasodilation | 1998 |
Modulation of long-term potentiation induction in the hippocampus by N-methyl-D-aspartate-mediated presynaptic inhibition.
Topics: Adenosine; Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Phosphoric Monoester Hydrolases; Protein Phosphatase 1; Rats; Receptors, Presynaptic; Tacrolimus | 1999 |
Presynaptic inhibition preferentially reduces in NMDA receptor-mediated component of transmission in rat midbrain dopamine neurons.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Cesium; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Agonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Mesencephalon; N-Methylaspartate; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Adenosine-amino acid interactions in the chick brain: a role in passive avoidance learning.
Topics: Adenosine; Animals; Avoidance Learning; Chickens; Corpus Striatum; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 1999 |
Effect of N-methyl-D-aspartate on motor activity and in vivo adenosine striatal outflow in the rat.
Topics: Adenosine; Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Influence of an extracellular acidosis on excitatory synaptic transmission and long-term potentiation in the CA1 region of rat hippocampal slices.
Topics: Acidosis; Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Cell Membrane; Cerebrospinal Fluid; Electric Stimulation; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sodium Bicarbonate; Sodium-Hydrogen Exchangers; Sulfuric Acids; Synaptic Transmission | 2000 |
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Antihypertensive Agents; Diazoxide; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glyburide; Hypoglossal Nerve; Hypoglycemic Agents; Hypoxia; Kainic Acid; Macrolides; Mice; Mitochondrial Swelling; N-Methylaspartate; Optics and Photonics; Organ Culture Techniques; Ouabain; Potassium Channels; Respiratory Center; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 2001 |
Suppression of presynaptic responses to adenosine by activation of NMDA receptors.
Topics: Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Agonists; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; N-Methylaspartate; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Time Factors; Triazines; Triazoles | 2001 |
Adenosine acting on A1 receptors protects NO-triggered rebound potentiation and LTP in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
Selective muscarinic regulation of functional glutamatergic Schaffer collateral synapses in rat CA1 pyramidal neurons.
Topics: Adenosine; Animals; Carbachol; Cholinergic Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Inhibition; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Muscarinic; Synapses | 2002 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2002 |
ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Nucleotides; Oocytes; Patch-Clamp Techniques; Protein Subunits; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2003 |
Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons.
Topics: Adenosine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Intracellular Space; Male; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pregnancy; Prosencephalon; Purinones; Rats; Rats, Sprague-Dawley; Thionucleotides | 2004 |
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Models, Biological; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Phenethylamines; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Triazines; Triazoles | 2004 |
Blockade of presynaptic adenosine A1 receptor responses by nitric oxide and superoxide in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Deaminase; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Superoxides; Time Factors; Xanthine | 2004 |
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Topics: Adenosine; Animals; Carbazoles; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Indoles; Male; Membrane Potentials; N-Methylaspartate; Phenethylamines; Phenylacetates; Pregnancy; Purinergic P1 Receptor Agonists; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Triazines; Triazoles | 2004 |
Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 2004 |
Adenosine protects cultured retinal neurons against NMDA-induced cell death through A1 receptors.
Topics: Adenosine; Animals; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Cytoprotection; Excitatory Amino Acid Agonists; Female; N-Methylaspartate; Neuroglia; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1; Retina; Trypan Blue | 2004 |
Adenosine mediation of presynaptic feedback inhibition of glutamate release.
Topics: Adenosine; Anesthetics, Local; Animals; Brain Stem; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback, Physiological; Glutamic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Bicuculline; Blotting, Western; Colforsin; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Fluorescent Antibody Technique; GABA Antagonists; Glycine; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenethylamines; Phenylacetates; Pregnancy; Presynaptic Terminals; Pyridines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Synaptophysin; Vesicular Glutamate Transport Protein 1 | 2005 |
The effect of acidosis on adenosine release from cultured rat forebrain neurons.
Topics: Acetates; Acidosis; Adenosine; Amiloride; Analysis of Variance; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Hydrogen-Ion Concentration; Methylamines; Models, Biological; N-Methylaspartate; Neurons; Neuroprotective Agents; Prosencephalon; Purines; Rats; Time Factors; Tritium | 2006 |
Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mossy Fibers, Hippocampal; N-Methylaspartate; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; Synapses; Triazoles | 2008 |
N-methyl-D-aspartic acid causes relaxation of porcine retinal arterioles through an adenosine receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Triphosphate; Animals; Arterioles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrolysis; Muscle, Smooth, Vascular; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Retinal Artery; Swine; Theophylline; Vasodilation | 2008 |
Expression of adenosine A 2A receptors in the rat lumbar spinal cord and implications in the modulation of N-methyl-d-aspartate receptor currents.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Glycine; Lumbosacral Region; Membrane Potentials; N-Methylaspartate; Pain; Patch-Clamp Techniques; Phenethylamines; Posterior Horn Cells; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Substantia Gelatinosa | 2008 |
Adenosine produced by neurons is metabolized to hypoxanthine by astrocytes.
Topics: Adenosine; Animals; Astrocytes; Brain; Cells, Cultured; Coculture Techniques; Excitatory Amino Acid Agonists; Hypoxanthine; N-Methylaspartate; Neurons; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley | 2008 |
N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Inosine; N-Methylaspartate; Neurons; Piperidines; Purines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2009 |
ATP-induced relaxation of porcine retinal arterioles in vitro depends on prostaglandin E synthesized in the perivascular retinal tissue.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arterioles; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; Muscle, Smooth, Vascular; Myography; N-Methylaspartate; Prostaglandins; Prostaglandins E; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Retinal Artery; Swine; Vasodilation | 2010 |
Modulation of the striato-pallidal pathway by adenosine A2a receptors depends on dopaminergic striatal input.
Topics: Action Potentials; Adenosine; Analysis of Variance; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Medial Forebrain Bundle; N-Methylaspartate; Neural Pathways; Neurons; Rats; Rats, Wistar; Receptors, Adenosine A2 | 2010 |
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2011 |
Synaptically driven state transitions in distal dendrites of striatal spiny neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine A2 Receptor Agonists; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Calcium; Calcium Channel Blockers; Corpus Striatum; Dendrites; Dopamine Agents; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mibefradil; Mice; Mice, Transgenic; Microscopy, Confocal; Models, Neurological; N-Methylaspartate; Nerve Net; Neurons; Nickel; Patch-Clamp Techniques; Phenethylamines; Spider Venoms; Synapses; Tetrodotoxin; Time Factors | 2011 |
A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Brain Infarction; Brain Injuries; Brain Ischemia; Cell Movement; Chemokine CCL2; Glucose; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Monocytes; N-Methylaspartate; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; Thionucleosides; Tumor Necrosis Factor-alpha | 2011 |
Purinergic modulation of the excitatory synaptic input onto rat striatal neurons.
Topics: Adenosine; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Synaptic Transmission | 2012 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine.
Topics: Adenosine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Immobilization; Ketamine; Male; Mice; N-Methylaspartate; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Serine; Swimming; Time Factors; Zinc Compounds | 2012 |
Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons.
Topics: Adenosine; Adenosine Deaminase; Animals; Calcium Channels; Cell Survival; Cerebral Cortex; HEK293 Cells; Humans; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptor, Adenosine A1; Tetracycline; Transfection; Up-Regulation; Xanthines | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Biosensing Techniques; CA1 Region, Hippocampal; Electric Stimulation; Exocytosis; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microelectrodes; N-Methylaspartate; Nucleoside Transport Proteins; SNARE Proteins | 2013 |
Autoregulation of retinal blood flow in response to decreased ocular perfusion pressure in cats: comparison of the effects of increased intraocular pressure and systemic hypotension.
Topics: Adenosine; Animals; Cats; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Excitatory Amino Acid Agonists; Female; Homeostasis; Hypotension; Intraocular Pressure; Intravitreal Injections; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Nitric Oxide; Ocular Hypertension; Regional Blood Flow; Retina; Vasodilator Agents | 2014 |
Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Xanthines | 2015 |
Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Animals, Newborn; Apoptosis; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique, Indirect; In Situ Nick-End Labeling; Intravitreal Injections; Male; N-Methylaspartate; Neuroprotection; Optic Nerve Injuries; Organ Culture Techniques; Rats; Rats, Wistar; Receptor, Adenosine A3; Retina; Retinal Degeneration; Retinal Neurons | 2015 |
DZNep protects against retinal ganglion cell death in an NMDA-induced mouse model of retinal degeneration.
Topics: Adenosine; Animals; Cell Count; Cell Death; Disease Models, Animal; Electroretinography; Intravitreal Injections; Male; Mice; N-Methylaspartate; Retinal Degeneration; Retinal Ganglion Cells | 2021 |
Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways.
Topics: Adenosine; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Genes, Immediate-Early; Glutamates; Haloperidol; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Receptors, Dopamine D1; TOR Serine-Threonine Kinases | 2022 |
Involvement of P2Y
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; N-Methylaspartate; Norepinephrine; Rats; Rats, Wistar | 2023 |