n-methylaspartate has been researched along with 6-cyano-7-nitroquinoxaline-2,3-dione in 368 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (3.26) | 18.7374 |
| 1990's | 237 (64.40) | 18.2507 |
| 2000's | 89 (24.18) | 29.6817 |
| 2010's | 27 (7.34) | 24.3611 |
| 2020's | 3 (0.82) | 2.80 |
| Authors | Studies |
|---|---|
| Fedorov, NB; Reymann, KG; Screbitsky, VG | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Manabe, T; Nicoll, RA; Renner, P | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Dudek, FE; Peacock, WJ; Wuarin, JP | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Kelly, JB; Wu, SH | 1 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Czepita, D; Daw, N; Fox, K; Sato, H | 1 |
| Nicklas, WJ; Zeevalk, GD | 2 |
| Weiland, NG | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Flavin, MP; Riopelle, RJ; Yang, Y | 1 |
| Pinnock, RD | 1 |
| Rekling, JC | 1 |
| Dingledine, R; McBain, C | 1 |
| Ault, B; Martin, D; Nadler, JV | 1 |
| Pittaluga, A; Raiteri, M | 2 |
| Cumberbatch, M; King, AE; Lopez-Garcia, JA | 1 |
| Kurusu, R; Sakurai, H; Sano, K; Tsuchiya, T; Tsuda, M | 1 |
| Lanius, RA; Shaw, C | 2 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Evans, PD; Merzon, RM; Reale, V; Villegas, J | 1 |
| Arai, A; Lynch, G; Muller, D | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Hablitz, JJ; Lee, WL | 1 |
| Crane, AM; Driscoll, BF; Law, MJ | 1 |
| Aizenman, E; Lipton, SA; Sucher, NJ | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Frenguelli, BG | 1 |
| Bovolin, P; Costa, E; Grayson, DR; Memo, M | 1 |
| Rosenberg, PA | 1 |
| Houk, JC; Keifer, J | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Choi, DW; Koh, JY | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Turner, DA; Wheal, HV | 1 |
| Lai, YY; Siegel, JM | 1 |
| Eaton, SA; Roberts, WA; Salt, TE | 1 |
| Schmidt, M | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Avoli, M; Hwa, GG | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Esguerra, M; Kwon, YH; Sur, M | 1 |
| Li, J; Smith, SS | 1 |
| Morita, Y; Nishimura, S; Sorimachi, M | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Coenen, AM; Peeters, BW; Ramakers, GM; Vossen, JM | 1 |
| Jean, A; Kessler, JP | 1 |
| Cerne, R; Gerber, G; Randić, M | 1 |
| Christenson, J; Grillner, S | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Guy, N; Ropert, N | 1 |
| Hankins, MW; Ikeda, H | 1 |
| Jacocks, HM; McMahon, PN; Werling, LL | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Kawai, N; Robinson, HP; Sahara, Y | 1 |
| Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N | 1 |
| Arancio, O; MacDermott, AB; Murase, K; Yoshimura, M | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Evans, RH; Long, SK; Siarey, RJ; Smith, DA | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Costa, E; Grayson, DR; Szekely, AM | 1 |
| Hestrin, S; Nicoll, RA; Perkel, DJ; Sah, P | 1 |
| Dudek, FE; van den Pol, AN; Wuarin, JP | 1 |
| Hablitz, JJ; Sutor, B | 1 |
| Aizenman, E; Loring, RH; Rosenberg, PA; White, WF | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Collingridge, GL; Davies, SN | 1 |
| Audinat, E; Gähwiler, BH; Knöpfel, T | 1 |
| Cler, JA; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Kerwin, R; Meldrum, B; Patel, S | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Jahr, CE; Lester, RA; Parker, JD; Quarum, ML; Weber, E | 1 |
| Harris, KM; Miller, RJ | 1 |
| Costa, E; Favaron, M; Guidotti, A; Manev, H | 1 |
| Choi, DW; Hartley, DM | 1 |
| Dubinsky, JM; Rothman, SM; Yamada, KA | 1 |
| Sheardown, MJ | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| Ben-Ari, Y; Cherubini, E; Gho, M; Neuman, RS | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 1 |
| Kauer, JA; Malenka, RC; Nicoll, RA | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Lerma, J; Mellström, B; Naranjo, JR; Paternain, AV | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Fedorov, NB; Reymann, KG | 1 |
| Jahr, CE; Tong, G | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Gyevai, A; Mike, A; Osipenko, O; Vizi, ES | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Bruno, VM; Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP | 1 |
| Madamba, SG; Nie, Z; Siggins, GR | 1 |
| Anderson, DK; Farooqui, AA; Horrocks, LA; Wells, K | 1 |
| Bockaert, J; Fagni, L; Lafon-Cazal, M; Quignard, JF; Rodriguez, J | 1 |
| Oja, SS; Saransaari, P | 2 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Ferreira, IL; Santos, PF | 1 |
| Köhling, R; Lücke, A; Moskopp, D; Speckmann, EJ; Straub, H; Wassmann, H | 1 |
| Dowling, JE; Grant, GB | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Hu, B; Nissen, R; Renaud, LP | 1 |
| Herron, C; Hjelmstad, GO; Malenka, RC; Nicoll, RA; Selig, DK | 1 |
| Hill, JM; Kaufman, MP; Wong, MK | 1 |
| D'Angelo, E; De Filippi, G; Rossi, P; Taglietti, V | 1 |
| Coco, S; Fumagalli, G; Matteoli, M; Verderio, C | 1 |
| Isaacson, JS; Walmsley, B | 1 |
| de Mello, FG; de Mello, MC; Kubrusly, RC; Reis, RA | 1 |
| Michaelis, EK; Michaelis, ML; Ragan, RE; Seah, EE; Xia, Y | 1 |
| Bushey, RM; Larson-Prior, LJ; Morrison, PD; Slater, NT | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Grosche, J; Kettenmann, H; Müller, T; Ohlemeyer, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Choi, DW; Goldberg, MP; Gottlieb, DI; Huettner, JE; Turetsky, DM | 1 |
| Constantine-Paton, M; Hickmott, PW | 1 |
| Greer, RA; Hall, ME; Stewart, JM | 1 |
| Fahey, JM; Lindquist, DG; Miller, LG; Pritchard, GA | 1 |
| Burke, JP; Hablitz, JJ | 2 |
| Churn, SB; DeLorenzo, RJ; Limbrick, D; Sombati, S | 1 |
| Magistretti, PJ; Pellerin, L; Stella, N | 1 |
| Hastings, TG; Reynolds, IJ | 1 |
| Derr-Yellin, E; Nicklas, WJ; Zeevalk, GD | 1 |
| Ni, B; Paul, SM; Weller, M; Wood, KA; Yan, GM | 1 |
| Opitz, T; Pidoplichko, VI; Reymann, KG; Shinozaki, H; Wilsch, VW | 1 |
| Fahey, JM; Miller, LG | 1 |
| Rajdev, S; Reynolds, IJ | 1 |
| Chetkovich, DM; Sweatt, JD | 1 |
| Abercrombie, ED; Keefe, KA; Sved, AF; Zigmond, MJ | 1 |
| López-Colomé, AM; Ortega, A; Romo-de-Vivar, M | 1 |
| Brooks, KJ; Kauppinen, RA | 1 |
| Heinemann, U; Igelmund, P; Leschinger, A; Stabel, J | 1 |
| Chazot, PL; Cik, M; Stephenson, FA | 1 |
| Fan, P; Szerb, JC | 1 |
| Nistri, A; Stocca, G | 1 |
| Puro, DG; Uchihori, Y | 1 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Bernard, J; Massicotte, G; Ohayon, M | 1 |
| Janáky, R; Oja, SS; Saransaari, P; Varga, V | 2 |
| Gallo, V; Mayer, ML; Patneau, DK; Vaccarino, FM | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Dai, X; Douglas, JR; Jordan, LM; Noga, BR | 1 |
| Kessler, JP | 1 |
| D'Angelo, E; Rossi, P; Taglietti, V | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Abercrombie, ED; Keefe, KA; Zigmond, MJ | 1 |
| Trombley, PQ; van den Pol, AN | 1 |
| Tang, CM; Yamada, KA | 1 |
| Buchwald, NA; Cohen, RW; Levine, MS; Radisavljevic, Z; Siviy, SM; Walsh, JP | 1 |
| Childers, WS; Greenough, WT; Weiler, IJ | 1 |
| Cordery, PM; Smith, AL; Thompson, ID | 1 |
| Morishita, W; Sastry, BR; Shew, TR | 1 |
| Karpefors, M; Niu, YP; Wigström, H; Xiao, MY | 2 |
| Benardo, LS | 1 |
| Altemus, KL; Cepeda, C; Colwell, CS; Levine, MS | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Klishin, A; Krishtal, O; Lozovaya, N; Tsintsadze, T | 1 |
| Jedema, HP; Moghddam, B | 1 |
| Avoli, M; Barbarosie, M; Köhling, R; Lopantsev, V; Lücke, A; Nagao, T | 1 |
| Auth, F; DeBoer, P; Moor, E; Westerink, BH | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Dudel, J; Parnas, H; Parnas, I; Ravin, R | 1 |
| Buisson, A; Choi, DW; Yu, SP | 1 |
| Kaneko, A; Sasaki, T | 1 |
| Avoli, M; Lopantsev, V | 1 |
| Andjus, PR; Cherubini, E; Khiroug, L; Nistri, A; Yakel, JL | 1 |
| Bisset, GW; Fairhall, KM | 1 |
| Akerman, KE; Holopainen, I; Janáky, R; Oja, SS; Varga, V | 1 |
| Carvalho, AP; Duarte, CB; Ferreira, IL | 1 |
| Kent, S; Kernahan, SD; Levine, S | 1 |
| Barrios, M; Liljequist, S | 1 |
| Hand, GA; Ordway, GA; Wilson, LB | 1 |
| Hori, Y; Kanda, K | 1 |
| Cumberbatch, MJ; Headley, PM; Herrero, JF | 1 |
| Caine, SB; Swerdlow, NR; Wan, FJ | 1 |
| Bong, GW; Firestein, GS; Rosengren, S | 1 |
| Ogawa, H; Otawa, S; Takagi, K | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Martin, LJ; Northington, FJ; Traystman, RJ | 1 |
| Kombian, SB; Pittman, QJ; Saleh, TM; Zidichouski, JA | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Altermatt, HJ; Arnold, A; Ehrenberger, K; Felix, D; Frenz, M; Pratisto, H; Weber, HP | 1 |
| Cristòfol, RM; Gassó, S; Griffiths, R; Rodríguez-Farré, E; Selema, G | 1 |
| Orrego, F; Riquelme, G; Villanueva, S; Wyneken, U | 1 |
| Durand, GM; Konnerth, A | 1 |
| Bhardwaj, A; Hanley, DF; Ichord, RN; Koehler, RC; Northington, FJ; Traystman, RJ | 1 |
| Basbaum, AI; Liu, H; Mantyh, PW | 1 |
| Belousov, AB; van den Pol, AN | 1 |
| Arnelle, DR; Choi, YB; D'Emilia, DM; Kim, WK; Kumar, S; Lipton, SA; Rayudu, PV; Stamler, JS | 1 |
| McCarthy, KD; Shao, Y | 1 |
| Baudry, M; Bi, X; Gellerman, DM | 1 |
| Frandsen, A; Griffiths, R; Malcolm, C; Meredith, C; Ritchie, L; Rumsby, P; Schousboe, A; Scott, M | 1 |
| Blasi, F; Guerrini, L; Kistler, B; Molteni, A; Wirth, T | 1 |
| Bunnett, NW; Grady, EF; Martínez, V; Marvizón, JC; Mayer, EA | 1 |
| Katz, LC; Roerig, B | 1 |
| Cazevieille, C; Osborne, NN; Safa, R | 1 |
| Arvanov, VL; Wang, RY | 1 |
| Kiehn, O; Kjaerulff, O | 1 |
| de Mello, FG; de Mello, MC; Kubrusly, RC | 1 |
| Aroniadou-Anderjaska, V; Ennis, M; Keller, A; Sheppard, NF; Shipley, MT; Yagodin, S; Zimmer, LA | 1 |
| Baird, DH; Console-Bram, LM; Fitzpatrick-McElligott, SG; McElligott, JG | 1 |
| Compagnone, NA; Mellon, SH | 1 |
| Constantine-Paton, M; Lin, SY | 1 |
| Delaney, SM; Geiger, JD; Shepel, PN | 1 |
| Crill, WE; Schwindt, PC | 1 |
| Beato, M; Bracci, E; Nistri, A | 1 |
| Bywood, PT; Johnson, SM | 1 |
| Farre, C; Jacobson, I; Jardemark, K; Orwar, O; Zare, RN | 1 |
| Baxter, KA; Church, J; McLarnon, JG | 1 |
| Niu, YP; Wigström, H; Xiao, MY | 1 |
| Mifflin, SW; Zhang, J | 1 |
| Elsworth, JD; Punch, LJ; Taylor, JR | 1 |
| Cairns, BE; Hu, JW; Sessle, BJ | 1 |
| DeFazio, T; Hablitz, JJ | 1 |
| Aramakis, VB; Metherate, R | 1 |
| Bongianni, F; Dubuc, R; Grillner, S; Ohta, Y; Vinay, L | 1 |
| Cuénod, M; Do, KQ; Grima, G; Mayer, B; Pfeiffer, S | 1 |
| Chandler, SH; Del Negro, CA | 1 |
| Fernandes, K; Malcangio, M; Tomlinson, DR | 1 |
| Fryer, HJ; Kalb, RG; Knox, RJ; Strittmatter, SM | 1 |
| D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G | 1 |
| LeDoux, JE; Weisskopf, MG | 1 |
| Chvátal, A; Syková, E; Ziak, D | 1 |
| Hargreaves, KM; Jackson, DL | 1 |
| Inoue, T; Murphy, DD; Pozzo-Miller, LD | 1 |
| Paschen, W | 1 |
| Fujisaki, T; Kudoh, M; Shibuki, K; Wakatsuki, H | 1 |
| Arnold, T; Ehrenberger, K; Felix, D; Kleinlogel, S; Oestreicher, E | 1 |
| Olkowski, JL; Slusher, BS; Thomas, AG; Vornov, JJ | 1 |
| Descombes, S; Psarropoulou, C | 1 |
| Chen, J; Li, H; Li, Z; Luo, C; Zheng, J | 1 |
| Chouvet, G; Dugast, C; Schmitt, P; Souliere, F | 1 |
| Bito, H; Deisseroth, K; Mermelstein, PG; Tsien, RW | 1 |
| Hirate, K; Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K; Teramoto, T | 1 |
| Cruise, L; Fuller, G; Ho, LK; Morris, BJ; Veitch, K | 2 |
| Bevilaqua da Rocha, B; de Mattos-Dutra, A; Kommers, T; Meirelles, R; Pessoa-Pureur, R; Wajner, M; Wofchuk, ST | 1 |
| Carlson, GC; Keller, A; Shipley, MT | 1 |
| Benarese, M; Boroni, F; Goffi, F; Pizzi, M; Spano, PF; Valerio, A | 1 |
| Arnold, A; Felix, D; Knipper, M; Oestreicher, E; Zenner, HP | 1 |
| Dong, XP; Wang, DS; Xu, TL | 1 |
| de la Peña, E; Geijo-Barrientos, E | 1 |
| McAllister, AK; Stevens, CF | 1 |
| Addae, JI; Ali, N; Evans, SM; Stone, TW | 1 |
| Maeda, M; Nakai, M | 1 |
| Hirai, H; Launey, T | 1 |
| Alford, S; Schwartz, NE | 1 |
| Adamchik, Y; Baskys, A | 1 |
| Li, YQ; Yang, K | 1 |
| Carbone, S; Moguilevsky, JA; Ponzo, O; Rondina, D; Scacchi, P; Szwarcfarb, B | 1 |
| Caicedo, A; Jafri, MS; Roper, SD | 1 |
| Kolb, JE; Levine, ES | 1 |
| Haga, M; Kinoshita, M; Moriyama, Y; Otsuka, M; Takeda, M; Tsuboi, S; Yamada, H | 1 |
| Chatton, JY; Magistretti, PJ; Marquet, P | 1 |
| Furuya, N; Hirate, K; Kitayama, A | 1 |
| Hashimoto, A; Kanda, J; Oka, T | 1 |
| Billard, JM; Dutar, P; Poindessous-Jazat, F; Potier, B | 1 |
| Dobbertin, A; Gervais, A; Glowinski, J; Mallat, M | 1 |
| Ruan, DY; Sui, L | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Akaike, A; Honda, K; Inoue, R; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Anderson, TR; Andrew, RD; Jarvis, CR | 1 |
| Inoue, N; Nakayama, T; Soga, TM | 1 |
| Onishchenko, NV; Petrov, VI; Sergeyev, VS | 1 |
| Haller, M; Mironov, SL; Richter, DW | 1 |
| Ai, J; Jardemark, KE; Ninan, I; Wang, RY | 1 |
| Cepeda, C; Hurst, RS; Levine, MS; Shumate, LW | 1 |
| Chvátal, A; Jendelová, P; Syková, E; Vargová, L | 1 |
| Huang, L; Pallas, SL | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P | 1 |
| Cartier, L; Infante, C; Motles, E | 1 |
| Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P | 1 |
| Soria, JM; Valdeolmillos, M | 1 |
| Frishman, LJ; Robson, JG; Viswanathan, S | 1 |
| Akaike, N; Carp, JS; Carpenter, DO; Hori, N | 1 |
| Bordey, A; Sontheimer, H | 1 |
| Iino, M; Kakegawa, W; Ozawa, S; Tsuzuki, K | 1 |
| Chai, CY; Hong, LZ | 1 |
| Arendt-Nielsen, L; Chen, J; Mørch, CD; You, HJ | 1 |
| Madden, CJ; Morrison, SF | 1 |
| Benz, B; Binns, KE; Do, KQ; Eaton, SA; Salt, TE | 1 |
| Darbon, P; Legrand, JC; Streit, J | 2 |
| Hu, B; Sun, SG; Tong, ET | 1 |
| Nistri, A; Taccola, G | 1 |
| Kakegawa, W; Kameyama, K; Ozawa, S; Tsuzuki, K; Yoshida, Y | 1 |
| Blitz, DM; Foster, KA; Regehr, WG | 1 |
| Hemby, SE; Joëls, M; Verkuyl, JM | 1 |
| Aarts, M; Arundine, M; Lau, A; Tymianski, M | 1 |
| Feng, GG; Hirokawa, M; Ishikawa, N; Komatsu, T; Kondo, H; Nishiwaki, K; Shimada, Y; Yokochi, T | 1 |
| Bringmann, A; Klaus, C; Reichenbach, A; Rillich, K; Syková, E; Uckermann, O; Ulbricht, E; Vargová, L; Weick, M; Wiedemann, P | 1 |
| Balthazart, J; Cornil, CA; Motte, P; Seutin, V | 1 |
| Kim, K; Lee, KH; Park, JY | 1 |
| Joëls, M; Karst, H; Verkuyl, JM | 1 |
| Hinckley, C; Seebach, B; Ziskind-Conhaim, L | 1 |
| Breitinger, HG; Frermann, D; Hollmann, M; Keller, BU; Paarmann, I; Villmann, C | 1 |
| Anderson, AJ; Garraway, SM; Mendell, LM | 1 |
| Jung, SJ; Kim, DK; Kim, J; Kim, SJ; Kim, YS | 1 |
| Takemoto, Y | 1 |
| Holland, SM; Kishida, KT; Klann, E; Pao, M | 1 |
| Jiang, X; Lipsky, RH; Marini, AM; Mearow, K; Okagaki, P; Tian, F | 1 |
| Chergui, K; Greengard, P; Svenningsson, P | 1 |
| Baig, R; Lacey, MG; Loucif, KC; Stanford, IM; Wilson, CL | 1 |
| Zheng, S; Zuo, Z | 1 |
| Grillner, S; Hill, RH; Tsvyetlynska, NA | 1 |
| Kartelija, G; Radenović, L; Selaković, V | 1 |
| Baillien, M; Ball, GF; Balthazart, J | 1 |
| Cohen, AS; Geddes-Klein, DM; Meaney, DF; Mesfin, MN; Serbest, G | 1 |
| Díaz-Ríos, M; Harris-Warrick, RM; Zhong, G | 1 |
| Choi, HC; Eun, BL; Kim, H; Kim, HJ; Kim, IH; Kim, SK; Lim, JH; Noh, MR; Park, SK; Sun, W | 1 |
| Buonanno, A; Logan, SM; Matta, JA; Partridge, JG; Vicini, S | 1 |
| Blizzard, CA; Chuah, MI; Chung, RS; Dickson, TC; Foster, SS; King, AE; Vickers, JC; West, AK | 1 |
| Bargas, J; Carrillo-Reid, L; Drucker-Colin, R; Galarraga, E; Hernández-Cruz, A; Tapia, D; Tecuapetla, F | 1 |
| Bargas, J; Galarraga, E; Guzman, JN; Lopez-Huerta, VG; Tecuapetla, F | 1 |
| Kass-Simon, G; Scappaticci, AA | 1 |
| Fu, WM; Lin, TH; Tang, CH; Wu, MY; Yang, RS | 1 |
| Chen, GD; Chen, SL; Cheng, CL; Huang, PC; Huang, YH; Kao, YL; Liao, JM; Lin, TB; Peng, HY; Tsai, SJ | 1 |
| Antonov, SM; Dvoretskova, EA; Evstratova, AA; Mironova, EV | 2 |
| Farb, DH; Gibbs, TT; Whittaker, MT | 1 |
| Bennett, MV; Rodenas-Ruano, A; Takayasu, Y; Takeuchi, K; Yang, Y; Zukin, RS | 1 |
| Al-Sarraf, H; Krajci, D; Mohammadi, S; Pavlik, A | 1 |
| Desfeux, A; El Ghazi, F; Gonzalez, BJ; Jégou, S; Laudenbach, V; Legros, H; Marret, S | 1 |
| Gean, PW; Lin, HC; Mao, SC; Su, CL | 1 |
| Martin, LJ; Orser, BA; Paulsen, O; Salter, MW; Vargas-Caballero, M | 1 |
| Abbas, AK; Afanasenkau, D; Huang, FS; Li, R; Wigström, H | 1 |
| Dergacheva, O; Jameson, H; Lovett-Barr, MR; Mendelowitz, D; Wang, X | 1 |
| Han, VZ; Magnus, G; Zhang, Y | 1 |
| Hall, BJ; Patrick, GN; Schwarz, LA | 1 |
| Gong, S; Guo, SY; Jiang, XH; Peng, JM; Tao, J; Wu, GC; Xu, LS; Yu, XM; Zhu, Q | 1 |
| Colledge, WH; d'Anglemont de Tassigny, X; Herbison, AE; Liu, X; Millar, R; Petersen, SL; Porteous, R | 1 |
| Kelley, BG; Luoma, JI; Mermelstein, PG | 1 |
| Moenter, SM; Roland, AV | 1 |
| Catenaccio, V; Jantos, H; Monti, JM; Xavier, S | 1 |
| Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L | 1 |
| Caviedes, A; González, A; Gundelfinger, ED; Kaehne, T; Michea, L; Pancetti, F; Sandoval, R; Smalla, KH; Wyneken, U | 1 |
| Gocel, J; Larson, J | 1 |
| Herbison, AE; Lee, K; Liu, X | 1 |
| Andrechek, E; Hollern, D; Liao, J; Wang, H; Zhou, X | 1 |
| Chen, D; Ding, L; Gao, R; Gao, XY; Kang, YM; Wang, JJ; Zhang, LL; Zhu, GQ | 1 |
| Akbarali, HI; Bowers, MS; Fitting, S; Hauser, KF; Knapp, PE; Marks, WD; Zou, S | 1 |
| Chang, JC; Chang, WP; Chen, IM; Cheng, JK; Chiu, HF; Lin, CH; Lin, CI; Lin, PH | 1 |
| Abreu, AR; Chianca, DA; da Silva, LG; de Abreu, AR; de Menezes, RC; de Souza, AA; Santos, LT | 1 |
| Alaux-Cantin, S; Antol, J; Fedorenko, O; Kervern, M; Naassila, M; Pierrefiche, O; Silvestre de Ferron, B | 1 |
| Hernan, AE; Pehek, EA | 1 |
| Hayashi, Y; Takahashi, M; Tanaka, J | 1 |
| Barberis, A; Cella Zanacchi, F; Das, S; Del Bue, A; Diaspro, A; Nieus, T; Pennacchietti, F; Petrini, EM; Rosillo, C; Tyagarajan, SK; Vascon, S | 1 |
| Araki, K; Higashiyama, S; Inamura, N; Iwakura, Y; Nawa, H; Takei, N; Wang, R | 1 |
| Chen, L; Huang, M; Jiang, B; Li, S; Li, Y; Wang, L; Wang, X; Yang, Y; Zhang, X | 1 |
| Berlin, JR; Nguyen, TD; Rojvirat, CP | 1 |
| Chen, X; Cheng, J; Kong, F; Wang, L; Wu, J; Xia, H; Zhong, L | 1 |
| Jahandideh, A; Jelokhani, M; Vazir, B; Zendehdel, M | 1 |
2 review(s) available for n-methylaspartate and 6-cyano-7-nitroquinoxaline-2,3-dione
| Article | Year |
|---|---|
Quinoxalinediones as excitatory amino acid antagonists in the vertebrate central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Binding, Competitive; Central Nervous System; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Spinal Cord; Structure-Activity Relationship; Vertebrates | 1990 |
Short-term synaptic plasticity: a comparison of two synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Humans; N-Methylaspartate; Neuronal Plasticity; Synapses; Synaptic Transmission | 2004 |
366 other study(ies) available for n-methylaspartate and 6-cyano-7-nitroquinoxaline-2,3-dione
| Article | Year |
|---|---|
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Phenols; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1992 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Synapses; Tetrodotoxin | 1992 |
The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Enkephalins; Functional Laterality; Gene Expression; Hippocampus; Kainic Acid; Kinetics; Male; Microinjections; N-Methylaspartate; Nucleic Acid Hybridization; Protein Precursors; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Single-electrode voltage-clamp analysis of the N-methyl-D-aspartate component of synaptic responses in neocortical slices from children with intractable epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Aging; Bicuculline; Cerebral Cortex; Child; Child, Preschool; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Female; Humans; Infant; Male; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1992 |
Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Bicuculline; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1992 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
NMDA, non-NMDA and glycine receptors mediate binaural interaction in the lateral superior olive: physiological evidence from mouse brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Functional Laterality; Glycine; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Olivary Nucleus; Quinoxalines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
The effect of visual experience on development of NMDA receptor synaptic transmission in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Cats; Darkness; Evoked Potentials; Iontophoresis; Light; N-Methylaspartate; Photic Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Vision, Ocular; Visual Cortex; Visual Perception | 1992 |
NMDA receptors, cellular edema, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Dizocilpine Maleate; Edema; Electron Transport; Glycolysis; Hypoglycemia; Hypoxia; Iodoacetates; Iodoacetic Acid; Ischemia; N-Methylaspartate; Potassium Cyanide; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Tetrodotoxin | 1992 |
Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Binding, Competitive; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Ovariectomy; Progesterone; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
The effect of hypoxia on neurotransmitter phenotype of forebrain cholinergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cell Hypoxia; Cells, Cultured; Choline O-Acetyltransferase; Embryo, Mammalian; Glutamates; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Growth Factors; Neurons; Phenotype; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Interaction between thyrotropin-releasing hormone (TRH) and NMDA-receptor-mediated responses in hypoglossal motoneurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Brain Stem; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1992 |
Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials, Somatosensory; Hippocampus; Hypertonic Solutions; In Vitro Techniques; Kainic Acid; Kinetics; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1992 |
NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Female; Hippocampus; In Vitro Techniques; Manganese; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Zinc | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. III. Changes in the NMDA receptor complex induced by their functional cooperation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1992 |
Antagonism of synaptic potentials in ventral horn neurones by 6-cyano-7-nitroquinoxaline-2,3-dione: a study in the rat spinal cord in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Electric Stimulation; Female; Half-Life; In Vitro Techniques; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Spinal Nerve Roots; Synapses | 1992 |
Stimulation of cultured cerebellar granule cells via glutamate receptors induces TRE- and CRE-binding activities mediated by common DNA-binding complexes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Cyclic AMP; DNA-Binding Proteins; Kainic Acid; Magnesium; Mice; Mice, Inbred ICR; Molecular Sequence Data; N-Methylaspartate; Protein Binding; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1992 |
Characterization and regulation of a high affinity [3H]CNQX labelled AMPA receptor in rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; Muscimol; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Neurotransmitter; Tritium | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
N-methyl-D-aspartate (NMDA) and non-NMDA (metabotropic) type glutamate receptors modulate the membrane potential of the Schwann cell of the squid giant nerve fibre.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Axons; Decapodiformes; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schwann Cells | 1992 |
Factors governing the potentiation of NMDA receptor-mediated responses in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
GABAA and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electricity; Epilepsy; Female; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Buffers; Cells, Cultured; Culture Media; Dizocilpine Maleate; Glutamates; Glutamic Acid; Mesencephalon; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cells, Cultured; Electrophysiology; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Retinal Ganglion Cells | 1991 |
Electrogenic uptake contributes a major component of the depolarizing action of L-glutamate in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport, Active; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synaptic Transmission | 1991 |
Regulation of gamma-aminobutyric acidA receptor subunit expression by activation of N-methyl-D-aspartate-selective glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamates; Glutamic Acid; Molecular Sequence Data; Muscimol; N-Methylaspartate; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger | 1991 |
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Role of excitatory amino acids in mediating burst discharge of red nucleus neurons in the in vitro turtle brain stem-cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Calcium; Cerebellum; Electric Stimulation; In Vitro Techniques; Iontophoresis; Magnesium; Microelectrodes; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Quisqualic Acid; Red Nucleus; Spinal Cord; Turtles | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Line; Cell Survival; Cerebral Cortex; Fetus; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Denervation; Evoked Potentials; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses | 1991 |
Pontomedullary glutamate receptors mediating locomotion and muscle tone suppression.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Female; Kainic Acid; Kinetics; Locus Coeruleus; Male; Medulla Oblongata; Motor Activity; Muscles; N-Methylaspartate; Pons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Mediation of visual responses in the nucleus of the optic tract in cats and rats by excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Evoked Potentials; Evoked Potentials, Visual; Female; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Optic Chiasm; Photic Stimulation; Quinoxalines; Quisqualic Acid; Rats; Receptors, Neurotransmitter | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
NMDA and non-NMDA receptors mediate visual responses of neurons in the cat's lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Visual Perception | 1991 |
GABAB receptor stimulation by baclofen and taurine enhances excitatory amino acid induced phosphatidylinositol turnover in neonatal rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Calcium; Cerebellum; gamma-Aminobutyric Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Receptors, GABA-A; Taurine | 1991 |
N-methyl-D-aspartate and aspartate raise the cytosolic free calcium concentration by acting upon receptors transiently expressed on immature cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Gallopamil; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Purkinje Cells; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
CNQX, a new non-NMDA receptor antagonist, reduces spike wave discharges in the WAG/Rij rat model of absence epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Azasteroids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Female; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Postural Balance; Pregnanediones; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Evidence that activation of N-methyl-D-aspartate (NMDA) and non-NMDA receptors within the nucleus tractus solitarii triggers swallowing.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Facial Nerve; Glutamates; Glutamic Acid; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in rat spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Serotonin; Synapses; Synaptic Transmission; Time Factors | 1991 |
Non-NMDA type excitatory amino acid receptors mediate rod input to horizontal cells in the isolated rat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Dark Adaptation; Membrane Potentials; N-Methylaspartate; Neurons; Photoreceptor Cells; Piperazines; Quinoxalines; Rats; Receptors, Amino Acid | 1991 |
Regulation of [3H]dopamine release from guinea pig striatum by NMDA receptor/channel activators and inhibitors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Glycine; Guinea Pigs; Ion Channels; Magnesium; Male; N-Methylaspartate; Piperazines; Pyrrolidines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1990 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Evoked Potentials; Hippocampus; Ion Channels; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Synapses | 1991 |
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P | 1991 |
Glutamate receptor agonist-induced inward currents in spinal dorsal horn neurons dissociated from the adult rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Ion Channels; Kainic Acid; N-Methylaspartate; Nerve Fibers; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord | 1991 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synapses; Tetrodotoxin | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Action of the anti-ischemic agent ifenprodil on N-methyl-D-aspartate and kainate-mediated excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Animals; Chick Embryo; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperidines; Quinoxalines; Retina | 1990 |
Transcriptional program coordination by N-methyl-D-aspartate-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Gene Expression; Immunoblotting; N-Methylaspartate; Neurons; Phencyclidine; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Transcription Factors; Transcription, Genetic | 1990 |
Excitatory synaptic currents in Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Synapses | 1990 |
Glutamate, the dominant excitatory transmitter in neuroendocrine regulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Calcium; Electric Stimulation; Glutamates; Glutamic Acid; Hypothalamus; Immunohistochemistry; Kainic Acid; Microscopy, Electron; N-Methylaspartate; Neurons; Neurotransmitter Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Second Messenger Systems; Synapses | 1990 |
Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electric Stimulation; Electrodes, Implanted; Evoked Potentials; Horseradish Peroxidase; Iontophoresis; Isoquinolines; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dihydroxyphenylalanine; Evoked Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Responses to excitatory amino acids of Purkinje cells' and neurones of the deep nuclei in cerebellar slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Animals, Newborn; Cells, Cultured; Cerebellar Nuclei; Cerebellum; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Rats | 1990 |
6,7-Dinitroquinoxaline-2,3-dione and 6-nitro,7-cyanoquinoxaline-2,3-dione antagonize responses mediated by N-methyl-D-aspartate and NMDA-associated glycine recognition sites in vivo: measurements of cerebellar cyclic-GMP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; Cyclic AMP; Glycine; Harmaline; Kinetics; Male; Mice; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Serine | 1990 |
Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Autoradiography; Female; Glutamates; Hippocampus; Humans; Kainic Acid; Male; Middle Aged; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; Schizophrenia; Tritium | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Interaction of 6-cyano-7-nitroquinoxaline-2,3-dione with the N-methyl-D-aspartate receptor-associated glycine binding site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Glycine; N-Methylaspartate; Quinoxalines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1989 |
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Biological Transport; Calcium; Cell Survival; Cells, Cultured; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Protein Kinase C; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Quantitative physiological characterization of a quinoxalinedione non-NMDA receptor antagonist.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Kainic Acid; Mathematics; N-Methylaspartate; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Synapses | 1989 |
A new and specific non-NMDA receptor antagonist, FG 9065, blocks L-AP4-evoked depolarization in rat cerebral cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1988 |
6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1988 |
A persistent postsynaptic modification mediates long-term potentiation in the hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Glutamates; Hippocampus; Membrane Potentials; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1988 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Functional kainate-selective glutamate receptors in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Embryo, Mammalian; Hippocampus; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Simultaneous local pressure microejection of excitatory amino acids and field potential recording with a single micropipette in the hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Hippocampus; In Vitro Techniques; Injections, Jet; Iontophoresis; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cytosol; Dizocilpine Maleate; Fetus; Glucose; Glutamic Acid; Glycine; Hypothermia, Induced; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurons | 1994 |
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Naloxone; Nucleus Accumbens; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 1994 |
Excitotoxicity of glutamate and four analogs in primary spinal cord cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acridine Orange; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Ethidium; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Staining and Labeling | 1994 |
Blockade of nitric oxide synthesis by tyrosine kinase inhibitors in neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Oxidoreductases; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Genistein; Isoflavones; Mice; N-Methylaspartate; Neostriatum; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phenols; Protein-Tyrosine Kinases | 1994 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
Taurine release from mouse hippocampal slices: effects of glutamatergic substances and hypoxia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxygen; Potassium; Quisqualic Acid; Taurine | 1994 |
Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Nicotinic Acids; Nipecotic Acids; Oximes; Quisqualic Acid; Retina; Tritium | 1994 |
Changes of extracellular calcium concentration induced by application of excitatory amino acids in the human neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Humans; In Vitro Techniques; Injections; Male; Membrane Potentials; N-Methylaspartate | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
Regulation of spontaneous phasic firing of rat supraoptic vasopressin neurones in vivo by glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Kainic Acid; Male; N-Methylaspartate; Oxytocin; Rats; Receptors, Glutamate; Supraoptic Nucleus; Vasopressins | 1995 |
Independent mechanisms for long-term depression of AMPA and NMDA responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Artifacts; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Pressor responses to stimulation of non-NMDA receptors in the superficial laminae of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Blood Pressure; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Microinjections; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Spinal Cord | 1995 |
Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebellum; Egtazic Acid; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin; Time Factors | 1995 |
Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cells, Cultured; Fetus; Glutamic Acid; Glycine; Hippocampus; Kinetics; Magnesium; N-Methylaspartate; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Synapses; Time Factors | 1995 |
Receptors underlying excitatory synaptic transmission in slices of the rat anteroventral cochlear nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Brain Stem; Cochlear Nucleus; Electric Stimulation; Evoked Potentials; Female; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors | 1995 |
Transient coupling of NMDA receptor with ip3 production in cultured cells of the avian retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Chick Embryo; Cycloleucine; Dizocilpine Maleate; gamma-Aminobutyric Acid; Inositol 1,4,5-Trisphosphate; Kainic Acid; N-Methylaspartate; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Retina; Time Factors | 1995 |
Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Calcium; Cellular Senescence; Cerebellum; Molecular Sequence Data; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Frequency dependent activation of a slow N-methyl-D-aspartate-dependent excitatory postsynaptic potential in turtle cerebellum by mossy fibre afferents.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Cerebellum; Electric Stimulation; Evoked Potentials; N-Methylaspartate; Presynaptic Terminals; Purkinje Cells; Turtles | 1995 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
NMDA-activated currents in Bergmann glial cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cell Membrane; Cerebellum; In Vitro Techniques; Ion Channels; Ketamine; Mice; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Carcinoma, Embryonal; Cell Differentiation; Dizocilpine Maleate; Electrophysiology; Female; Immunohistochemistry; Indicators and Reagents; Ion Channels; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Pregnancy; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tretinoin; Tumor Cells, Cultured | 1993 |
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rana pipiens; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Tetrodotoxin; Thalamus | 1993 |
Effects of L-glutamate, substance P and substance P(1-7) on cardiovascular regulation in the nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reference Values; Stereotaxic Techniques; Substance P | 1993 |
Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Fura-2; Glycine; N-Methylaspartate; Nimodipine; Pregnenolone; Spermine | 1995 |
Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Epilepsy; Evoked Potentials; Humans; Infant, Newborn; N-Methylaspartate; Neurons; Rats; Receptors, Metabotropic Glutamate | 1995 |
Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Aggregation; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Glycine; Hippocampus; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kinetics; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Neurotoxins; Peptides; Phosphorylation; Potassium Chloride; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Modulation of the glutamate-evoked release of arachidonic acid from mouse cortical neurons: involvement of a pH-sensitive membrane phospholipase A2.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amiloride; Ammonium Chloride; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Female; Glutamic Acid; Harmaline; Hydrogen-Ion Concentration; Immunohistochemistry; Kainic Acid; Kinetics; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Phospholipases A; Phospholipases A2; Pregnancy; Time Factors; Tritium | 1995 |
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indomethacin; Kainic Acid; Kinetics; Masoprocol; N-Methylaspartate; Neurons; Nitroarginine; Prosencephalon; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Time Factors | 1995 |
NMDA receptor involvement in toxicity to dopamine neurons in vitro caused by the succinate dehydrogenase inhibitor 3-nitropropionic acid.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Antihypertensive Agents; Cells, Cultured; Dizocilpine Maleate; Dopamine; Mesencephalon; N-Methylaspartate; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antimetabolites; Apoptosis; Cells, Cultured; Cerebellum; Culture Media; Dizocilpine Maleate; DNA; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1994 |
Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Glycine; Hippocampus; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
Interleukin-1 modulates GABAergic and glutamatergic function in brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Calcium; Cells, Cultured; Chick Embryo; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Interleukin-1; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Recombinant Proteins; Spermine; Tumor Necrosis Factor-alpha | 1994 |
Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: effect of chemical ischemia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Nimodipine; Potassium Chloride; Potassium Cyanide; Prosencephalon; Rats; Rats, Sprague-Dawley | 1994 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Stress-induced dopamine release in the neostriatum: evaluation of the role of action potentials in nigrostriatal dopamine neurons or local initiation by endogenous excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Dopamine; Electroshock; Homovanillic Acid; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Psychological; Substantia Nigra; Tetrodotoxin | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Pharmacological and electrographic properties of epileptiform activity induced by elevated K+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Carbachol; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quaternary Ammonium Compounds; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Temperature | 1993 |
Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Cell Death; Cell Line; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Transfection | 1993 |
Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CA1 pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Ammonium Chloride; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1993 |
Modulation by TRH of NMDA-elicited responses of CA1 neurones of the rat hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1994 |
Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Middle Aged; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction | 1993 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
Modulation of the AMPA receptor by phospholipase A2: effect of the antidepressant trimipramine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Drug Synergism; Hippocampus; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Synaptic Membranes; Synaptic Transmission; Trimipramine | 1994 |
Glutamate agonists and [3H]GABA release from rat hippocampal slices: involvement of metabotropic glutamate receptors in the quisqualate-evoked release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Excitatory amino acid receptors in glial progenitor cells: molecular and functional properties.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, Immediate-Early; Glutamic Acid; Immediate-Early Proteins; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Oligodendroglia; Rats; Receptors, Glutamate; Stem Cells; Transcription Factors | 1994 |
Release of [3H]GABA evoked by glutamate agonists from hippocampal slices: effects of dithiothreitol and glutathione.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Dithiothreitol; Dizocilpine Maleate; GABA Agonists; gamma-Aminobutyric Acid; Glutathione; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Magnesium; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tritium | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
The effects of intrathecal administration of excitatory amino acid agonists and antagonists on the initiation of locomotion in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Decerebrate State; Electromyography; Glutamates; Glutamic Acid; Hindlimb; Injections, Spinal; Kainic Acid; Laminectomy; Locomotion; Motor Activity; Muscles; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Spinal Cord; Time Factors | 1993 |
Involvement of excitatory amino acids in the activity of swallowing-related neurons of the ventro-lateral medulla.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Dipeptides; Electric Stimulation; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Different proportions of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Bicuculline; Cerebellum; Cytoplasmic Granules; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kinetics; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons; Neurons, Afferent; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
Glutamate neurons in hypothalamus regulate excitatory transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus; Microscopy, Electron; N-Methylaspartate; Neurites; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
High-affinity kainate binding sites in living slices of rat neocortex: characterization and regulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Veratridine | 1993 |
Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Cell Line; Cells, Cultured; Diazoxide; Diuretics; Electric Stimulation; Evoked Potentials; Hippocampus; Humans; Kainic Acid; Membrane Potentials; Molecular Structure; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Structure-Activity Relationship; Synapses; Time Factors | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
Calcium ion impedes translation initiation at the synapse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cerebral Cortex; Cycloleucine; Depression, Chemical; Gene Expression Regulation; Ionophores; Long-Term Potentiation; N-Methylaspartate; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Biosynthesis; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Ribosomes; RNA, Messenger; Sulfonamides; Synapses | 1996 |
Manufacture and release characteristics of Elvax polymers containing glutamate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Carriers; Drug Implants; Excitatory Amino Acid Antagonists; Ferrets; Molecular Weight; N-Methylaspartate; Piperazines; Polyvinyls; Receptors, Glutamate | 1995 |
Presynaptic actions of glutamate receptor agonists in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1995 |
The complementary nature of long-term depression and potentiation revealed by dual component excitatory postsynaptic potentials in hippocampal slices from young rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
N-methyl-D-aspartate transmission modulates GABAB-mediated inhibition of rat hippocampal pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; N-Methylaspartate; Organophosphorus Compounds; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Cyclopentanes; GABA Agonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microscopy, Video; Motor Activity; N-Methylaspartate; Neostriatum; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reference Values | 1996 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Latent N-methyl-D-aspartate receptors in the recurrent excitatory pathway between hippocampal CA1 pyramidal neurons: Ca(2+)-dependent activation by blocking A1 adenosine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Dizocilpine Maleate; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Models, Neurological; N-Methylaspartate; Picrotoxin; Potassium Chloride; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline; Time Factors | 1995 |
Characterization of excitatory amino acid modulation of dopamine release in the prefrontal cortex of conscious rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Consciousness; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1996 |
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Disease Models, Animal; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists | 1996 |
Septal and hippocampal glutamate receptors modulate the output of acetylcholine in hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Septal Nuclei | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Glutamate depresses release by activating non-conventional glutamate receptors at crayfish nerve terminals.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astacoidea; Axons; Calcium; Cell Membrane; Electric Conductivity; Electric Stimulation; Fura-2; Glutamic Acid; Muscles; N-Methylaspartate; Nerve Endings; Perfusion; Quisqualic Acid; Receptors, Glutamate; Synapses; Time Factors | 1996 |
DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclopropanes; Glycine; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotoxins; Pertussis Toxin; Receptors, Metabotropic Glutamate; Virulence Factors, Bordetella | 1996 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Reverberation of chloride-dependent synaptic potentials in the rat entorhinal cortex in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chloride Channels; Chlorides; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Periodicity; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Changes in intracellular calcium induced by NMDA in cultured rat hippocampal neurons require exogenous glycine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Microscopy, Confocal; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1996 |
Release of vasopressin and oxytocin by excitatory amino acid agonists and the effect of antagonists on release by muscarine and hypertonic saline, in the rat in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diuresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Muscarine; Muscarinic Agonists; N-Methylaspartate; Oxytocin; Rats; Rats, Wistar; Saline Solution, Hypertonic; Urodynamics; Vasoconstrictor Agents; Vasopressins | 1996 |
Endogenous gamma-L-glutamylglutamate is a partial agonist at the N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebellum; Dipeptides; Drug Synergism; Glutamates; Glutamic Acid; Glycine; Magnesium; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Ca2+ influx through glutamate receptor-associated channels in retina cells correlates with neuronal cell death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Cell Death; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuroprotective Agents; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina | 1996 |
Effects of excitatory amino acids on the hypothalamic-pituitary-adrenal axis of the neonatal rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hypothalamo-Hypophyseal System; Kainic Acid; Male; N-Methylaspartate; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Stress, Physiological; Time Factors | 1996 |
Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Carcinogens; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1996 |
Microdialysis of a non-NMDA receptor antagonist into the L7 dorsal horn attenuates the pressor response to static muscle contraction but not passive stretch in cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart Rate; Lidocaine; Lumbosacral Region; Microdialysis; Muscle Contraction; Muscle Spindles; N-Methylaspartate; Reflex; Spinal Cord | 1996 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Postpartum Period; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Studies of synaptic transmission in vivo: indirect versus direct effects of (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid/kainate antagonists on rat spinal sensory responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Iontophoresis; Male; Microelectrodes; N-Methylaspartate; Neurons, Afferent; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord; Synaptic Transmission | 1996 |
The ventral subiculum modulation of prepulse inhibition is not mediated via dopamine D2 or nucleus accumbens non-NMDA glutamate receptor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1996 |
Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Inflammatory Agents; Carrageenan; Catheterization; Central Nervous System; Dexamethasone; Excitatory Amino Acid Antagonists; Inflammation; N-Methylaspartate; Neutrophils; Peroxidase; Phenethylamines; Propionates; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Skin; Spinal Cord; Theobromine | 1996 |
NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Kainic Acid; N-Methylaspartate; Neurons; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Taste | 1995 |
Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Biomarkers; Calcium Channels; Citrulline; Cycloleucine; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Microdialysis; Muscle Proteins; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Tetrodotoxin | 1997 |
Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cholecystokinin; Devazepide; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; Interneurons; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Neurotensin; Patch-Clamp Techniques; Phenylurea Compounds; Pons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin | 1997 |
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1997 |
Experimental erbium laser surgery in the guinea pig cochlea: its use in the study of afferent cochlear neurotransmitters.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Erbium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Laser Therapy; Male; Microelectrodes; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission | 1996 |
Sulphur-containing amino acids modulate noradrenaline release from hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Sulfur; Animals; Calcium; Cobalt; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Magnesium; Male; N-Methylaspartate; Norepinephrine; Organ Culture Techniques; Rats; Rats, Wistar; Sensitivity and Specificity; Stereoisomerism; Tetrodotoxin; Tritium | 1997 |
Effect of glutamate receptor phosphorylation by endogenous protein kinases on electrical activity of isolated postsynaptic densities of rat cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cerebral Cortex; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kainic Acid; Long-Term Potentiation; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses | 1997 |
Long-term potentiation as a mechanism of functional synapse induction in the developing hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electric Stimulation; Evoked Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1996 |
Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrulline; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
NMDA-receptor regulation of substance P release from primary afferent nociceptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Injections, Spinal; N-Methylaspartate; Neurons, Afferent; Nociceptors; Pain; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Presynaptic; Spinal Cord; Substance P | 1997 |
Local synaptic release of glutamate from neurons in the rat hypothalamic arcuate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium Channels; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Models, Neurological; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1997 |
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Responses of Bergmann glia and granule neurons in situ to N-methyl-D-aspartate, norepinephrine, and high potassium.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Animals; Benzoates; Calcium; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fluorescent Dyes; Glycine; N-Methylaspartate; Neuroglia; Neurons; Norepinephrine; Organic Chemicals; Potassium; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1997 |
NMDA receptor-mediated regulation of AMPA receptor properties in organotypic hippocampal slice cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calpain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Molecular Weight; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Tritium | 1997 |
Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1997 |
Glutamate-dependent activation of NF-kappaB during mouse cerebellum development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Antibody Specificity; Cell Nucleus; Cerebellum; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Injections, Intraperitoneal; Mice; Mice, Transgenic; N-Methylaspartate; Neuroprotective Agents; Neurotransmitter Agents; NF-kappa B; Transgenes | 1997 |
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1997 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Hypoxia, Brain; L-Lactate Dehydrogenase; Melatonin; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxygen; Rats; Reactive Oxygen Species | 1997 |
NMDA-induced response in pyramidal neurons of the rat medial prefrontal cortex slices consists of NMDA and non-NMDA components.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Crossed rhythmic synaptic input to motoneurons during selective activation of the contralateral spinal locomotor network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Chlorides; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Glycine Agents; Locomotion; Motor Neurons; N-Methylaspartate; Neural Inhibition; Periodicity; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine; Synaptic Transmission | 1997 |
Aspartate as a selective NMDA receptor agonist in cultured cells from the avian retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Retina | 1998 |
Functional organization of rat olfactory bulb glomeruli revealed by optical imaging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Male; N-Methylaspartate; Olfactory Bulb; Organ Culture Techniques; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Tetrodotoxin | 1998 |
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Calcium; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Fetus; Glycine; Humans; Mice; N-Methylaspartate; Neocortex; Neurites; Neurons; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Steroid 17-alpha-Hydroxylase | 1998 |
Suppression of sprouting: An early function of NMDA receptors in the absence of AMPA/kainate receptor activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Magnesium; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Qa-SNARE Proteins; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Tetrodotoxin; Xenopus | 1998 |
Levels of endogenous adenosine in rat striatum. I. Regulation by ionotropic glutamate receptors, nitric oxide and free radicals.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Corpus Striatum; Dizocilpine Maleate; Free Radicals; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1998 |
Synaptically evoked dendritic action potentials in rat neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Iontophoresis; Male; Motor Cortex; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium Channels; Somatosensory Cortex; Tetrodotoxin | 1998 |
Extracellular K+ induces locomotor-like patterns in the rat spinal cord in vitro: comparison with NMDA or 5-HT induced activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Excitatory Amino Acid Agonists; Locomotion; N-Methylaspartate; Patch-Clamp Techniques; Periodicity; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Synaptic Transmission | 1998 |
Excitatory amino acid-induced degeneration of dendrites of catecholamine neurons in rat substantia nigra.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Catecholamines; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1998 |
Screening of receptor antagonists using agonist-activated patch clamp detection in chemical separations.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Electrophoresis, Capillary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Ion Channels; Mathematics; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Cell Surface | 1998 |
pH modulation of Ca2+ responses and a Ca2+-dependent K+ channel in cultured rat hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Fetus; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Methylamines; N-Methylaspartate; Neurons; Nifedipine; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar | 1998 |
Variability of AMPA and NMDA receptor mediated responses in CA1 pyramidal cells of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
A comparison of the effects of clonidine and CNQX infusion into the locus coeruleus and the amygdala on naloxone-precipitated opiate withdrawal in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Amygdala; Animals; Clonidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Locus Coeruleus; Male; Morphine Dependence; N-Methylaspartate; Naloxone; Narcotic Antagonists; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1998 |
Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Brain Stem; Dose-Response Relationship, Drug; Electromyography; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Jaw; Kainic Acid; Lidocaine; Male; Masseter Muscle; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Nerve | 1998 |
Excitability changes in freeze-induced neocortical microgyria.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain; Cerebral Cortex; Electric Stimulation; Epilepsy; Freezing; Functional Laterality; Humans; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley | 1998 |
Nicotine selectively enhances NMDA receptor-mediated synaptic transmission during postnatal development in sensory neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Critical Period, Psychological; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Somatosensory Cortex; Synaptic Transmission | 1998 |
Spinal inputs from lateral columns to reticulospinal neurons in lampreys.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Isotonic Solutions; Lampreys; Locomotion; Magnesium; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Ringer's Solution; Spinal Cord; Synaptic Transmission | 1998 |
Arginine availability controls the N-methyl-D-aspartate-induced nitric oxide synthesis: involvement of a glial-neuronal arginine transfer.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cerebellum; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1998 |
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei | 1998 |
NMDA receptor activation modulates evoked release of substance P from rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Capsaicin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1998 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Distinct populations of NMDA receptors at subcortical and cortical inputs to principal cells of the lateral amygdala.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amygdala; Animals; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thalamus | 1999 |
Glutamate-, kainate- and NMDA-evoked membrane currents in identified glial cells in rat spinal cord slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Membrane; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroglia; Oligodendroglia; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord | 1998 |
Activation of excitatory amino acid receptors in bovine dental pulp evokes the release of iCGRP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Cattle; Dental Pulp; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Radioimmunoassay; Receptors, Glutamate; Statistics, Nonparametric | 1999 |
Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; N-Methylaspartate; Pyramidal Cells; Rats | 1999 |
Potentiation and depression following stimulus interruption in young rat hippocampi.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Nifedipine; Rats; Rats, Sprague-Dawley; Reference Values | 1999 |
Calcium neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcimycin; Calcium; Cell Survival; Dizocilpine Maleate; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins | 1999 |
Irreversible impairment of inhibitory neurons and nitric oxide release in the neocortex produced by low temperature and hypoxia in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cell Hypoxia; Cold Temperature; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; Male; Muscimol; N-Methylaspartate; Neocortex; Neural Inhibition; Nitric Oxide; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Metabotropic glutamate receptors group I are involved in cochlear neurotransmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Indans; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Carboxypeptidases; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fetus; Glutamate Carboxypeptidase II; Glycine; Methotrexate; N-Methylaspartate; Neurons; Neurotoxins; Organophosphorus Compounds; Potassium Cyanide; Pyrrolidines; Rats | 1999 |
Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Animals, Newborn; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; N-Methylaspartate; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1999 |
Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bee Venoms; Cats; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; N-Methylaspartate; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Regulation of substantia nigra pars reticulata neuronal activity by excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substantia Nigra | 1999 |
Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression; Hippocampus; Ion Channel Gating; N-Methylaspartate; Phosphorylation; Pyramidal Cells; Rats | 2000 |
[The ameliorating effects of a novel NC-1900 on impairments of learning/memory caused by glutamic acid].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Avoidance Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kainic Acid; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Resorcinols | 1999 |
Kainate receptors activate NF-kappaB via MAP kinase in striatal neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcimycin; Calcium; Cells, Cultured; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; Immunohistochemistry; In Vitro Techniques; Ionophores; Kainic Acid; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; NF-kappa B; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Transcription Factor RelA | 2000 |
Methylmalonic and propionic acids increase the in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of young rats through NMDA glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Cytoskeletal Proteins; Glutamic Acid; In Vitro Techniques; Methylmalonic Acid; N-Methylaspartate; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Propionates; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Long-lasting depolarizations in mitral cells of the rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Cell Survival; Choline O-Acetyltransferase; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2000 |
Neurotrophin 3 potentiates glutamatergic responses of IHC afferents in the cochlea in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Carbazoles; Cochlea; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; In Vitro Techniques; Indole Alkaloids; Male; N-Methylaspartate; Nerve Fibers; Neurotrophin 3; Receptor, trkB; Receptor, trkC; Synapses | 2000 |
N-methyl-D-aspartate enhancement of the glycine response in the rat sacral dorsal commissural neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Spinal Cord | 2000 |
Participation of low-threshold calcium spikes in excitatory synaptic transmission in guinea pig medial frontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Frontal Lobe; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; N-Methylaspartate; Potassium Acetate; Pyramidal Cells; Synaptic Transmission | 2000 |
Nonsaturation of AMPA and NMDA receptors at hippocampal synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Iontophoresis; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2000 |
NMDA-induced changes in a cortical network in vivo are prevented by AMPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Nerve Net; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Cerebral cortical muscarinic cholinergic and N-methyl-D-aspartate receptors mediate increase in cortical blood flow elicited by chemical stimulation of periaqueductal gray matter.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Scopolamine; Stimulation, Chemical; Vasodilation; Vasodilator Agents | 2000 |
The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Cell Count; Cell Differentiation; Cells, Cultured; Dendrites; Excitatory Amino Acid Antagonists; Glycine; Intracellular Fluid; N-Methylaspartate; Nitric Oxide; Purkinje Cells; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Physiological activation of presynaptic metabotropic glutamate receptors increases intracellular calcium and glutamate release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Brain Stem; Calcium; Chromones; Cycloleucine; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorometry; Glutamic Acid; Glycine Agents; GTP-Binding Proteins; In Vitro Techniques; Lampreys; Larva; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Neuroprotective Agents; Patch-Clamp Techniques; Presynaptic Terminals; Quisqualic Acid; Receptors, Metabotropic Glutamate; Strychnine; Tetrodotoxin | 2000 |
Glutamate-mediated neuroprotection against N-methyl-D-aspartate toxicity: a role for metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cell Death; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Oligodeoxyribonucleotides, Antisense; Organ Culture Techniques; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Tetrodotoxin | 2000 |
Postsynaptic origin of N-methyl-D-aspartate-induced slow currents in substantia gelatinosa neurons: an in vitro voltage-clamp study in adult rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substantia Gelatinosa | 2000 |
Interrelationships of GABAergic, serotoninergic and excitatory amino acid systems in its regulatory effect on prolactin secretion in prepubertal rats.
Topics: 5-Hydroxytryptophan; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acids; Female; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Kainic Acid; N-Methylaspartate; p-Chloroamphetamine; Prolactin; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serotonin; Sexual Maturation | 2000 |
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds | 2000 |
Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Brain-Derived Neurotrophic Factor; Cell Membrane; Cells, Cultured; Excitatory Amino Acid Antagonists; Guanosine Triphosphate; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Blotting, Northern; Calcium; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gene Expression; Humans; Intracellular Fluid; Kainic Acid; N-Methylaspartate; Photoreceptor Cells, Vertebrate; Receptors, Glutamate; Retinoblastoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
Roles of glutamate receptor subtypes in the development of vestibular compensation after unilateral labyrinthectomy in the guinea pig.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Azepines; Denervation; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ear, Inner; Functional Laterality; Guinea Pigs; Kainic Acid; Male; Muscle Relaxants, Central; N-Methylaspartate; Neuronal Plasticity; Nystagmus, Pathologic; Oxazolidinones; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Time Factors; Vestibular Nerve; Vestibular Nuclei | 2000 |
Effects of N-methyl-D-aspartate, kainate or veratridine on extracellular concentrations of free D-serine and L-glutamate in rat striatum: an in vivo microdialysis study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Perfusion; Rats; Rats, Wistar; Serine; Time Factors; Veratridine | 2000 |
NMDA receptor activation in the aged rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2000 |
Activation of ionotropic glutamate receptors reduces the production of transforming growth factor-beta2 by developing neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta | 2000 |
Impairment of the Ca2+-permeable AMPA/kainate receptors by lead exposure in organotypic rat hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Biological Transport; Calcium; Cobalt; Glutamic Acid; Hippocampus; Lead; N-Methylaspartate; Organ Culture Techniques; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 2000 |
Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Glutamates; Hypothalamo-Hypophyseal System; Kainic Acid; Kinetics; Male; N-Methylaspartate; Organ Culture Techniques; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 2001 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Ischemia; Cortical Spreading Depression; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia; Kynurenic Acid; Male; N-Methylaspartate; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2001 |
Expression and regulation of Na pump isoforms in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cerebellum; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Potassium Radioisotopes; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2001 |
The effect of N-acetyl-L-aspartic acid dilithium salt on dopamine release and synthesis in the rat striatum in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Rats; Rats, Wistar; Time Factors | 2001 |
Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Corpus Striatum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Wortmannin | 2001 |
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Antihypertensive Agents; Diazoxide; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glyburide; Hypoglossal Nerve; Hypoglycemic Agents; Hypoxia; Kainic Acid; Macrolides; Mice; Mitochondrial Swelling; N-Methylaspartate; Optics and Photonics; Organ Culture Techniques; Ouabain; Potassium Channels; Respiratory Center; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 2001 |
Biphasic modulation of NMDA-induced responses in pyramidal cells of the medial prefrontal cortex by Y-931, a potential atypical antipsychotic drug.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Phencyclidine; Piperazines; Prefrontal Cortex; Pyramidal Cells; Rats | 2001 |
Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Glutamate, NMDA, and AMPA induced changes in extracellular space volume and tortuosity in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Chelating Agents; Diffusion; Dizocilpine Maleate; Edema; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Gliosis; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Spinal Cord | 2001 |
NMDA antagonists in the superior colliculus prevent developmental plasticity but not visual transmission or map compression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Mapping; Cricetinae; Electrophysiologic Techniques, Cardiac; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Mesocricetus; N-Methylaspartate; Neuronal Plasticity; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Visual Fields; Visual Pathways; Visual Perception | 2001 |
Effects of metabotropic glutamate receptor agonists and antagonists on D-aspartate release from mouse cerebral cortical and striatal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Metabotropic Glutamate; Tritium | 2001 |
Induction and blockade of epileptic foci by intracerebral injection of glutamatergic agonists and antagonists in frerly moving cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Seizures | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Receptor-activated calcium signals in tangentially migrating cortical cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Calcium; Calcium Signaling; Cell Movement; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA-A Receptor Agonists; Kainic Acid; Male; Muscimol; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Tetrodotoxin | 2002 |
Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques. Macaque photopic sinusoidal flicker ERG.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Electroretinography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Light; Macaca mulatta; Male; N-Methylaspartate; Photic Stimulation; Photoreceptor Cells; Pipecolic Acids; Retina; Tetrodotoxin | 2002 |
Corticospinal transmission to motoneurons in cervical spinal cord slices from adult rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Iontophoresis; Male; Motor Neurons; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission | 2002 |
Modulation of glutamatergic transmission by bergmann glial cells in rat cerebellum in situ.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Communication; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Neuroglia; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium; Synaptic Transmission | 2003 |
Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Immunohistochemistry; Infections; Luminescent Proteins; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, N-Methyl-D-Aspartate; Sindbis Virus; Valine | 2003 |
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves | 2003 |
Role of central NMDA versus non-NMDA receptor in spinal withdrawal reflex in spinal anesthetized rats under normal and hyperexcitable conditions.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Anesthesia; Animals; Bee Venoms; Central Nervous System; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hindlimb; Inflammation; Male; Muscle, Skeletal; N-Methylaspartate; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Spinal Cord Injuries | 2003 |
Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adipose Tissue, Brown; Animals; Bicuculline; Blood Pressure; Body Temperature Regulation; Carbon Dioxide; Dinoprostone; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exhalation; GABA Antagonists; Heart Rate; Male; Microinjections; N-Methylaspartate; Preoptic Area; Prostaglandins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System; Thermogenesis | 2003 |
Release of homocysteic acid from rat thalamus following stimulation of somatosensory afferents in vivo: feasibility of glial participation in synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Homocysteine; Iontophoresis; Kainic Acid; Male; Methionine; N-Methylaspartate; Neuroglia; Physical Stimulation; Piperazines; Rats; Rats, Wistar; Sulfur Isotopes; Synaptic Transmission; Thalamus; Vibrissae | 2004 |
Contributions of NMDA receptors to network recruitment and rhythm generation in spinal cord cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Apamin; Bicuculline; Cells, Cultured; Drug Interactions; Electric Stimulation; Electrodes; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Low micromolar concentrations of 4-aminopyridine facilitate fictive locomotion expressed by the rat spinal cord in vitro.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Locomotion; N-Methylaspartate; Nerve Net; Rats; Rats, Wistar; Spinal Cord | 2004 |
Input- and subunit-specific AMPA receptor trafficking underlying long-term potentiation at hippocampal CA3 synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Count; Cell Line; Cricetinae; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Luminescent Proteins; Models, Neurological; Mossy Fibers, Hippocampal; N-Methylaspartate; Protein Subunits; Protein Transport; Pyramidal Cells; Rats; Receptors, AMPA; Sindbis Virus; Synapses; Synaptic Transmission; Transfection | 2004 |
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Northern; Body Weight; Chronic Disease; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Organ Size; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Time Factors | 2004 |
Vulnerability of central neurons to secondary insults after in vitro mechanical stretch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Brain Injuries; Calpain; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; DNA; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Porphyrins; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Stress, Mechanical; Superoxide Dismutase | 2004 |
A role for L-glutamate ionotropic receptors in the development of rat neurogenic pulmonary edema.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Blood Proteins; Body Fluids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fibrin; Fourth Ventricle; Glutamic Acid; Heart Rate; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proteins; Pulmonary Edema; Rats; Rats, Wistar; Receptors, Glutamate; Vagus Nerve | 2004 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes | 2004 |
Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Coturnix; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Isonicotinic Acids; Kainic Acid; Male; N-Methylaspartate; Neurons; Norepinephrine; Preoptic Area; Pyridazines; Sympathomimetics | 2004 |
NMDA receptor-mediated calcium influx plays an essential role in myoblast fusion.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adaptor Proteins, Signal Transducing; Animals; Calcimycin; Calcium; Carrier Proteins; Cell Differentiation; Cell Fusion; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ionophores; Mice; Myoblasts, Skeletal; N-Methylaspartate; Nerve Tissue Proteins; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Thapsigargin | 2004 |
GABAergic transmission in the rat paraventricular nucleus of the hypothalamus is suppressed by corticosterone and stress.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corticosterone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Synaptic Transmission; Time Factors | 2005 |
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Motor Activity; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 2005 |
Kinetics and subunit composition of NMDA receptors in respiratory-related neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Respiration; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valine | 2005 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Long-term potentiation of silent synapses in substantia gelatinosa neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synapses | 2005 |
Depressor responses to L-proline microinjected into the rat ventrolateral medulla are mediated by ionotropic excitatory amino acid receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Proline; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2005 |
NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcysteine; Animals; Azoles; Blotting, Western; Catalase; Catecholamines; Dopamine Agonists; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Hippocampus; Imidazolines; In Vitro Techniques; Isoindoles; Lysine; Metalloporphyrins; Mice; Mice, Inbred C57BL; N-Methylaspartate; NADPH Oxidases; Neurons; NG-Nitroarginine Methyl Ester; Organoselenium Compounds; Patch-Clamp Techniques; Phosphorylation; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 2005 |
The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Antibodies; Autocrine Communication; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Time Factors; Tyrosine | 2005 |
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Casein Kinase 1 epsilon; Casein Kinase I; Casein Kinase Ialpha; Casein Kinase Idelta; Corpus Striatum; Egtazic Acid; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 2005 |
Functional interconnectivity between the globus pallidus and the subthalamic nucleus in the mouse brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Apamin; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; In Vitro Techniques; Lysine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Net; Neurons; Picrotoxin; Subthalamic Nucleus | 2005 |
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
Role of AMPA receptor desensitization and the side effects of a DMSO vehicle on reticulospinal EPSPs and locomotor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Benzothiadiazines; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Lampreys; Motor Activity; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Neurons; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2005 |
Effects of brain-derived neurotrophic factor (BDNF) on activity mediated by NMDA receptors in rat spinal cord cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Antibodies; Brain-Derived Neurotrophic Factor; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neural Inhibition; Neurons; Organ Culture Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine | 2005 |
Mitochondrial superoxide production and MnSOD activity after exposure to agonist and antagonists of ionotropic glutamate receptors in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Kainic Acid; Mitochondria; N-Methylaspartate; Rats; Receptors, Kainic Acid; Superoxide Dismutase; Superoxides; Time Factors | 2005 |
Rapid control of brain aromatase activity by glutamatergic inputs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Brain; Coturnix; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate | 2006 |
Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytosol; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Antagonists; Gene Expression Regulation; N-Methylaspartate; Neurons; Nimodipine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Thiazoles; Thiazolidines | 2006 |
Intrinsic and functional differences among commissural interneurons during fictive locomotion and serotonergic modulation in the neonatal mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Interneurons; Locomotion; Membrane Potentials; Mice; Mice, Inbred ICR; N-Methylaspartate; Patch-Clamp Techniques; Periodicity; Serotonin; Spinal Cord | 2006 |
Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Cell Hypoxia; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Maze Learning; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Topiramate | 2006 |
Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Time Factors | 2007 |
Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Microtubule-Associated Proteins; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurofilament Proteins; Rats; Receptors, Glutamate; Spinal Cord; Time Factors | 2007 |
Encoding network states by striatal cell assemblies.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Calcium; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Models, Neurological; N-Methylaspartate; Nerve Net; Neural Pathways; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Rats; Rats, Wistar; Substance P | 2008 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
NMDA and GABA B receptors are involved in controlling nematocyst discharge in hydra.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Drug; Epinephrine; Glutamic Acid; Glycine; Hydra; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, GABA-B; Serotonin | 2008 |
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Male; N-Methylaspartate; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Phosphorylation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tibia; Time Factors | 2008 |
Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anal Canal; Anesthesia; Animals; Bicuculline; Electric Stimulation; Electromyography; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gallamine Triethiodide; gamma-Aminobutyric Acid; N-Methylaspartate; Neural Inhibition; Neuromuscular Nondepolarizing Agents; Pelvis; Rats; Rats, Wistar; Reflex; Spinal Cord; Urethra; Urination | 2008 |
[Apoptosis and its receptor selective pathways during neurotoxic action of glutamate].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53 | 2008 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 2009 |
NMDA preconditioning and neuroprotection in vivo: delayed onset of kainic acid-induced neurodegeneration and c-Fos attenuation in CA3a neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Dizocilpine Maleate; Female; Gene Expression; Genes, fos; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2009 |
Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53 | 2009 |
Dual effect of glutamate on GABAergic interneuron survival during cerebral cortex development in mice neonates.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Calcium; Caspase 3; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; N-Methylaspartate; Necrosis; RNA, Small Interfering | 2010 |
Alterations of excitatory transmission in the lateral amygdala during expression and extinction of fear memory.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Behavior, Animal; Cycloserine; Electric Stimulation; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; In Vitro Techniques; Male; Membrane Potentials; Memory; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission | 2010 |
alpha5 Subunit-containing GABA(A) receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Imidazoles; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Knockout; N-Methylaspartate; Neural Inhibition; Neural Pathways; Pyramidal Cells; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Zolpidem | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine | 2010 |
Electrophysiological characteristics of cells in the anterior caudal lobe of the mormyrid cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Biophysics; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Electric Fish; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lysine; Membrane Potentials; Mice; N-Methylaspartate; Nerve Fibers; Patch-Clamp Techniques; Purkinje Cells; Sodium Channel Blockers; Tetrodotoxin | 2010 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Enhanced NMDA receptor NR1 phosphorylation and neuronal activity in the arcuate nucleus of hypothalamus following peripheral inflammation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arcuate Nucleus of Hypothalamus; Blotting, Western; Dizocilpine Maleate; Glutamic Acid; Inflammation; Male; N-Methylaspartate; Phosphorylation; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley | 2011 |
Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Dihydrotestosterone; Enzyme Activation; Estrogens; Female; GABA Antagonists; Glucose; Gonadotropin-Releasing Hormone; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Ovariectomy; Ribonucleotides; Valine | 2011 |
Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Sleep; Sleep Deprivation; Sleep, REM | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Arginine; Bicuculline; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebral Cortex; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Guanylate Cyclase; Hippocampus; Intracellular Fluid; Larva; Male; N-Methylaspartate; Neurons; Nitric Oxide; Post-Synaptic Density; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptosomes; Xenopus | 2011 |
Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Burst firing in gonadotrophin-releasing hormone neurones does not require ionotrophic GABA or glutamate receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Organ Culture Techniques; Receptors, GABA-A; Receptors, Ionotropic Glutamate; Synaptic Potentials; Synaptic Transmission | 2012 |
NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Cell Death; Cell Survival; Cerebral Cortex; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation; Memantine; N-Methylaspartate; Neurons; Nifedipine; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Transcription, Genetic | 2013 |
Superoxide anions in paraventricular nucleus modulate adipose afferent reflex and sympathetic activity in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Adipose Tissue, White; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Cyclic N-Oxides; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Spin Labels; Superoxide Dismutase; Superoxides; Sympathetic Nervous System | 2013 |
Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; AIDS-Associated Nephropathy; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Morphine; N-Methylaspartate; Primary Cell Culture; Receptors, Opioid, mu; Ryanodine; Sodium; Synapses; tat Gene Products, Human Immunodeficiency Virus | 2014 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
Amygdalar neuronal activity mediates the cardiovascular responses evoked from the dorsolateral periaqueductal gray in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Arterial Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; Glutamic Acid; Heart Rate; Male; Microinjections; Muscimol; N-Methylaspartate; Neurons; Periaqueductal Gray; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate | 2015 |
Aberrant NMDA-dependent LTD after perinatal ethanol exposure in young adult rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Central Nervous System Depressants; Electric Stimulation; Ethanol; Excitatory Amino Acid Agents; Female; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2015 |
Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Valine; Ventral Tegmental Area | 2015 |
Glutamatergic modulation of noradrenaline release in the rat median preoptic area.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Preoptic Area; Quisqualic Acid; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2017 |
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; Animals; Carrier Proteins; Cells, Cultured; Computer Simulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Hippocampus; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Peptides; Polymers; Post-Synaptic Density; Receptors, GABA-A; Valine | 2017 |
Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; ADAM17 Protein; Animals; Blotting, Western; Cell Membrane; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamates; Kainic Acid; N-Methylaspartate; Neuregulin-1; Neurons; Prosencephalon; Protein Kinase C; Protein Precursors; Proteolysis; Rats, Sprague-Dawley; Serotonin | 2017 |
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclin-Dependent Kinase 5; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Neurons; Phosphopyruvate Hydratase; Piperidines; Pyridazines; Sensory Deprivation; Visual Cortex; Visual Pathways | 2018 |
Evaluating spatial and network properties of NMDA-dependent neuronal connectivity in mixed cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; N-Methylaspartate; Neurons; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2022 |
Endogenous Cannabinoid Receptors Modulate Plasticity at Immature Synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Endocannabinoids; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Cannabinoid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Dorsal Horn; Synapses | 2022 |
Interactions of Cholecystokinin and Glutamatergic Systems in Feeding Behavior of Neonatal Chickens.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Chickens; Cholecystokinin; Dizocilpine Maleate; Eating; Feeding Behavior; N-Methylaspartate; Receptors, Glutamate | 2022 |