n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride and rasagiline

n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride has been researched along with rasagiline in 2 studies

Compound Research Comparison

Studies (n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride)	Trials (n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride)	Recent Studies (post-2010) (n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride)	Studies (rasagiline)	Trials (rasagiline)	Recent Studies (post-2010) (rasagiline)
6	0	0	535	72	314

Protein Interaction Comparison

Protein	Taxonomy	rasagiline (IC50)
Cholinesterase	Homo sapiens (human)	2.3865
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	1.0029
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	0.2115
Amine oxidase [flavin-containing] A	Homo sapiens (human)	1.088
Acetylcholinesterase	Homo sapiens (human)	0.019
Amine oxidase [flavin-containing] B	Homo sapiens (human)	0.2217

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Finberg, JP; Youdim, MB	1
Miklya, I	1

Other Studies

2 other study(ies) available for n-methyl-n-propargyl-(1-indanyl)-ammonium hydrochloride and rasagiline

Article	Year
MAO type B inhibitors as adjunct to L-dopa therapy. Advances in neurology, 1987, Volume: 45 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkynes; Animals; Brain; Drug Therapy, Combination; Humans; Indans; Isoenzymes; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Selegiline; Structure-Activity Relationship; Tyramine	1987
[A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:1 Topics: Adrenergic Uptake Inhibitors; Animals; Brain Stem; Catecholamines; Clorgyline; Indans; Learning; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Pargyline; Rats; Selegiline; Tetrabenazine	2008

Article

Year

MAO type B inhibitors as adjunct to L-dopa therapy.

Advances in neurology, 1987, Volume: 45

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkynes; Animals; Brain; Drug Therapy, Combination; Humans; Indans; Isoenzymes; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Selegiline; Structure-Activity Relationship; Tyramine

1987

[A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508].

Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:1

Topics: Adrenergic Uptake Inhibitors; Animals; Brain Stem; Catecholamines; Clorgyline; Indans; Learning; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Pargyline; Rats; Selegiline; Tetrabenazine

2008