Compounds > n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide

n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide and glycocyamine

n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide has been researched along with glycocyamine* in 1 studies

Other Studies

1 other study(ies) available for n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide and glycocyamine

Article	Year
Determination of creatine and guanidinoacetate by GC-MS: study of their stability in urine at different temperatures. Clinical biochemistry, 2009, Volume: 42, Issue:1-2 Evaluation of a GC-MS method using N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) as the silylating agent for GC-MS. Study of the stability of creatine and guanidinoacetate in urine.. 22 urines were kept at RT, 4 degrees C and -30 degrees C for 15 days.. MTBSTFA produces a single chromatographic peak in contrast with other derivatizing agents. Creatine concentration increases at room temperature (326% on average), and at 4 degrees C (75%). However, detection decreases after freezing (-37%). Guanidinoacetate is stable, but decreases after freezing (-37%). Sonication before analysis is crucial to obtain repetitive results.. A modified GC-MS method has been validated and the conditions for preservation of the urine have been established. Topics: Acetamides; Creatine; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Organosilicon Compounds; Temperature; Trifluoroacetic Acid	2009

Article

Year

Determination of creatine and guanidinoacetate by GC-MS: study of their stability in urine at different temperatures.

Clinical biochemistry, 2009, Volume: 42, Issue:1-2

Evaluation of a GC-MS method using N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) as the silylating agent for GC-MS. Study of the stability of creatine and guanidinoacetate in urine.. 22 urines were kept at RT, 4 degrees C and -30 degrees C for 15 days.. MTBSTFA produces a single chromatographic peak in contrast with other derivatizing agents. Creatine concentration increases at room temperature (326% on average), and at 4 degrees C (75%). However, detection decreases after freezing (-37%). Guanidinoacetate is stable, but decreases after freezing (-37%). Sonication before analysis is crucial to obtain repetitive results.. A modified GC-MS method has been validated and the conditions for preservation of the urine have been established.

Topics: Acetamides; Creatine; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Organosilicon Compounds; Temperature; Trifluoroacetic Acid

2009