Compounds > n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide

n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide and 17alpha-ethynylestr-5(10)-ene-3alpha-17beta-diol

n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide has been researched along with 17alpha-ethynylestr-5(10)-ene-3alpha-17beta-diol* in 1 studies

Other Studies

1 other study(ies) available for n-methyl-n-(tert-butyldimethylsilyl)trifluoroacetamide and 17alpha-ethynylestr-5(10)-ene-3alpha-17beta-diol

Article	Year
Suitability of N,O-bis(trimethylsilyl)trifluoroacetamide and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide as derivatization reagents for the determination of the estrogens estrone and 17alpha-ethinylestradiol by gas chromatography-mass spectrome Journal of chromatography. A, 2004, Feb-13, Volume: 1026, Issue:1-2 This paper describes apreviously unreported problem with the use of N,O-bis-(trimethylsilyl)trifluoroacetamide (BSTFA) and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA) to derivatise the natural hormone estrone (E1) and the synthetic estrogen 17alpha-ethinylestradiol (EE2). The resulting trimethylsilyl (TMS) and t-butyldimethylsilyl (TBS) derivatives of EE2 were partially converted to their respective El derivatives. Therefore, these reagents may not be suitable for simultaneous determination of estrogens in environmental samples, which raises questions about the reliability of results from some earlier studies. Topics: Acetamides; Environment; Estrone; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Molecular Structure; Norethynodrel; Organosilicon Compounds; Reproducibility of Results; Trifluoroacetic Acid; Trimethylsilyl Compounds	2004

Article

Year

Suitability of N,O-bis(trimethylsilyl)trifluoroacetamide and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide as derivatization reagents for the determination of the estrogens estrone and 17alpha-ethinylestradiol by gas chromatography-mass spectrome

Journal of chromatography. A, 2004, Feb-13, Volume: 1026, Issue:1-2

This paper describes apreviously unreported problem with the use of N,O-bis-(trimethylsilyl)trifluoroacetamide (BSTFA) and N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA) to derivatise the natural hormone estrone (E1) and the synthetic estrogen 17alpha-ethinylestradiol (EE2). The resulting trimethylsilyl (TMS) and t-butyldimethylsilyl (TBS) derivatives of EE2 were partially converted to their respective El derivatives. Therefore, these reagents may not be suitable for simultaneous determination of estrogens in environmental samples, which raises questions about the reliability of results from some earlier studies.

Topics: Acetamides; Environment; Estrone; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Molecular Structure; Norethynodrel; Organosilicon Compounds; Reproducibility of Results; Trifluoroacetic Acid; Trimethylsilyl Compounds

2004