n-methyl-3,4-methylenedioxyamphetamine and s,n,n'-tripropylthiocarbamate

n-methyl-3,4-methylenedioxyamphetamine has been researched along with s,n,n'-tripropylthiocarbamate in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.56)18.7374
1990's3 (4.69)18.2507
2000's25 (39.06)29.6817
2010's31 (48.44)24.3611
2020's4 (6.25)2.80

Authors

AuthorsStudies
Bird, M; Hubner, CB; Kornetsky, C; Rassnick, S1
Amendola, CA; Fishkin, MD; Hubbell, CL; Reid, LD; Tsai, J1
Imel, KM; Obradovic, T; Wheaton, MJ; White, SR1
Atrens, DM; Christie, MJ; Jackson, DM; Lin, HQ; McGregor, IS1
Ashby, CR; Gardner, EL; Horan, B1
Ball, M; Beckett, SR; Fone, KC; Maddocks, L; Swettenham, J; Topham, IA1
Kovar, KA; Mayerhofer, A; Meyer, A; Schmidt, WJ1
Lingford-Hughes, A; Nutt, D1
Cole, JC; Marsden, CA; O'Shea, E; Sumnall, HR1
Cole, JC; Sumnall, HR1
Achat-Mendes, C; Anderson, KL; Itzhak, Y1
de la Torre, R; Kieffer, BL; Maldonado, R; Mendizabal, V; Ortuño, J; Robledo, P1
Achat-Mendes, C; Ali, SF; Itzhak, Y1
Braida, D; Sala, M1
Capuani, EM; Herzig, V; Kovar, KA; Schmidt, WJ1
Canales, JJ; Rodriguez-Alarcón, G; Salvador, A1
Cornish, JL; Hargreaves, GA; Hunt, GE; McGregor, IS1
Aguilar, MA; Daza-Losada, M; Manzanedo, C; Miñarro, J; Ribeiro Do Couto, B; Rodríguez-Arias, M1
Hamon, M; Lanfumey, L; Lesch, KP; Maldonado, R; Renoir, T; Robledo, P; Trigo, JM1
de la Torre, R; Maldonado, R; Panayi, F; Robledo, P; Trigo, JM1
Kindlundh-Högberg, AM; Schiöth, HB; Svenningsson, P1
Cardon, AL; Diller, AJ; Nation, JR; Rocha, A; Valles, R; Wellman, PJ1
Chen, HI; Cherng, CG; Huang, AM; Jen, CJ; Kuo, YM; Liao, CH; Su, SW; Yu, L1
Cheung, BK; Ho, AM; Leung, FY; Loxton, NJ; Stadlin, A; Tam, N; Wan, VL1
Kankaanpää, A; Kurling, S; Seppälä, T1
Hanson, KL; Luciana, M; Sullwold, K1
Ikemoto, S; Liu, ZH; Qin, M; Shin, R1
Duvauchelle, CL; Feduccia, AA1
Ben-Hamida, S; Cassel, JC; de Vasconcelos, AP; Jackisch, R; Jones, BC; Kelche, C; Lazarus, C1
Angstadt, M; Bedi, G; de Wit, H; Phan, KL1
Colado, MI; Izco, M; Lopez-Jimenez, A; Lopez-Moreno, JA; Mayado, A; O'Shea, E; Peraile, I; Torres, E1
Robledo, P1
Maldonado, R; Plaza-Zabala, A; Robledo, P; Viñals, X1
Aguilar, MA; Daza-Losada, M; Maldonado, C; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M1
Carretón, O; Ledent, C; Ruiz-Medina, J; Valverde, O1
Aguilar, MA; Armario, A; Do Couto, BR; Fuentes, S; Gagliano, H; Miñarro, J; Rodríguez-Arias, M1
Albaugh, DL; Baumann, MH; Riley, AL; Rinker, JA; Sink, JR1
Francis, AJ; Smerdon, MJ1
Blanco, E; Casas, M; Cormand, B; Fernàndez-Castillo, N; Maldonado, R; Orejarena, MJ; Ribasés, M; Robledo, P1
Baker, LE; Panos, JJ1
Aguilar, MA; Daza-Losada, M; Guerri, C; Miñarro, J; Nadal, R; Ribeiro Do Couto, B; Rodríguez-Arias, M; Summavielle, T1
Bowen, MT; McGregor, IS1
Costa, G; Fenu, S; Morelli, M; Pinna, A; Plumitallo, A; Simola, N1
Izenwasser, S; Matos, J; Stagg, M; Starosciak, AK; Zakharova, E1
Becker, B; Daumann, J; Gouzoulis-Mayfrank, E; Koester, P; Tittgemeyer, M; Volz, KG; Wagner, D1
Aguilar, MA; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M; Roger-Sánchez, C1
Rodríguez-Árias, M; Valverde, O1
Aguilar, MA; Miñarro, J; Rodríguez-Arias, M; Roger-Sánchez, C3
Aguilar, MA; Arenas, MC; Manzanedo, C; Mateos-García, A; Miñarro, J; Rodriguez-Arias, M; Roger-Sánchez, C1
Aguilar, MA; García-Pardo, MP; Maldonado, C; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M1
Caminer, A; Goodwin, J; Hicks, C; McGregor, IS; Ramos, L1
Aguilar, MA; García-Pardo, MP; Miñarro, J; Rodríguez-Arias, M; Roger-Sánchez, C1
Braida, D; Ponzoni, L; Sala, M1
Aguilar, MA; García-Pardo, MP; Miñarro, J; Rodríguez-Arias, M1
Aguilar, MA; García-Pardo, MP; Miñarro, J1
Carhart-Harris, RL; Gabay, AS; Kempton, MJ; Mazibuko, N; Mehta, MA; Morrison, PD; Nutt, DJ1
Aguilar, MA; Felipo, V; García-Pardo, MP; Llansola, M; Miñarro, J1
Gore, S; Huber, R; Sprague, JE; van Staaden, MJ1
Cardozo Pinto, DF; Heifets, BD; Hoerbelt, P; Malenka, RC; Salgado, JS; Steinberg, EE; Sze, JY; Taylor, MD; Walsh, JJ1
Hirayama, S; Hokazono, M; Iwase, Y; Masukawa, D; Mori, T; Suzuki, T; Udagawa, Y; Uzawa, N1
Braida, D; Brennan, CH; Ponzoni, L; Sala, M; Teh, MT; Torres-Perez, JV1
Aguilar, MA; Calpe-López, C; De la Rubia Ortí, JE; García-Pardo, MP1

Reviews

8 review(s) available for n-methyl-3,4-methylenedioxyamphetamine and s,n,n'-tripropylthiocarbamate

ArticleYear
The effects of methylenedioxymethamphetamine (MDMA, "Ecstasy") on monoaminergic neurotransmission in the central nervous system.
    Progress in neurobiology, 1996, Volume: 49, Issue:5

    Topics: Action Potentials; Animals; Brain; Brain Damage, Chronic; Dopamine; Fever; Guinea Pigs; Haplorhini; Hippocampus; Humans; Hyperkinesis; Hypoglossal Nerve; Illicit Drugs; Motor Neurons; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Nucleus Accumbens; Prefrontal Cortex; Raphe Nuclei; Rats; Reward; Serotonin; Substance-Related Disorders; Synaptic Transmission; Tegmentum Mesencephali

1996
Neurobiology of addiction and implications for treatment.
    The British journal of psychiatry : the journal of mental science, 2003, Volume: 182

    Topics: Behavior, Addictive; Dopamine; Heroin Dependence; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders

2003
The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA).
    Neuroscience and biobehavioral reviews, 2003, Volume: 27, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Carrier Proteins; Conditioning, Psychological; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hallucinogens; Illicit Drugs; Membrane Glycoproteins; Membrane Transport Proteins; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Reward; Serotonin Plasma Membrane Transport Proteins

2003
Endocannabinoids and 3,4-methylenedioxymethamphetamine (MDMA) interaction.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:2

    Topics: Animals; Cannabinoid Receptor Modulators; Cannabis; Drug Interactions; Endocannabinoids; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Reinforcement, Psychology; Reward

2005
Cannabinoids, opioids and MDMA: neuropsychological interactions related to addiction.
    Current drug targets, 2010, Volume: 11, Issue:4

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Addictive; Brain; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Humans; Marijuana Abuse; Mice; Mice, Knockout; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Opioid Peptides; Opioid-Related Disorders; Rats; Receptors, Opioid; Reinforcement, Psychology; Reward

2010
Breaking the loop: oxytocin as a potential treatment for drug addiction.
    Hormones and behavior, 2012, Volume: 61, Issue:3

    Topics: Adaptation, Psychological; Alcoholism; Animals; Drug Tolerance; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Reward; Self Administration; Social Behavior; Social Environment; Substance Withdrawal Syndrome; Substance-Related Disorders

2012
Modulation of 3,4-methylenedioxymethamphetamine effects by endocannabinoid system.
    Current pharmaceutical design, 2013, Volume: 19, Issue:40

    Topics: Amphetamine-Related Disorders; Animals; Cannabinoids; Cannabis; Cognition Disorders; Endocannabinoids; Humans; Marijuana Abuse; N-Methyl-3,4-methylenedioxyamphetamine; Reinforcement, Psychology; Reward; Time Factors

2013
Neurochemical substrates of the rewarding effects of MDMA: implications for the development of pharmacotherapies to MDMA dependence.
    Behavioural pharmacology, 2016, Volume: 27, Issue:2-3 Spec I

    Topics: Animals; Brain; Conditioning, Psychological; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Neurotransmitter; Reward; Substance-Related Disorders

2016

Trials

3 trial(s) available for n-methyl-3,4-methylenedioxyamphetamine and s,n,n'-tripropylthiocarbamate

ArticleYear
Effects of MDMA on sociability and neural response to social threat and social reward.
    Psychopharmacology, 2009, Volume: 207, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Blood Pressure; Brain; Brain Mapping; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Hallucinogens; Heart Rate; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; N-Methyl-3,4-methylenedioxyamphetamine; Oxygen; Pain Measurement; Pattern Recognition, Visual; Photic Stimulation; Reward; Social Behavior; Young Adult

2009
Decision-making in polydrug amphetamine-type stimulant users: an fMRI study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Amphetamines; Brain; Central Nervous System Stimulants; Decision Making; Female; Humans; Magnetic Resonance Imaging; Male; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Young Adult

2013
Psilocybin and MDMA reduce costly punishment in the Ultimatum Game.
    Scientific reports, 2018, 05-29, Volume: 8, Issue:1

    Topics: Adult; Altruism; Community-Based Participatory Research; Decision Making; Emotions; Games, Experimental; Healthy Volunteers; Humans; Interpersonal Relations; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Psilocybin; Psychopharmacology; Punishment; Rejection, Psychology; Reward; Social Behavior; Socialization; Young Adult

2018

Other Studies

53 other study(ies) available for n-methyl-3,4-methylenedioxyamphetamine and s,n,n'-tripropylthiocarbamate

ArticleYear
The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Brain; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred F344; Reward

1988
Naltrindole, a delta-opioid antagonist, blocks MDMA's ability to enhance pressing for rewarding brain stimulation.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:2

    Topics: Animals; Brain; Electric Stimulation; Male; Medial Forebrain Bundle; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reward; Self Stimulation; Serotonin Agents

1996
Serotonergic modulation of 3,4-methylenedioxymethamphetamine (MDMA)-elicited reduction of response rate but not rewarding threshold in accumbal self-stimulation.
    Brain research, 1997, Jan-09, Volume: 744, Issue:2

    Topics: Animals; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Self Stimulation; Sensory Thresholds; Serotonin

1997
Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3, 4-methylenedioxymethamphetamine (MDMA).
    Synapse (New York, N.Y.), 2000, Volume: 35, Issue:2

    Topics: Animals; Appetite; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward

2000
Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity.
    Psychopharmacology, 2002, Volume: 159, Issue:4

    Topics: Age Factors; Animals; Body Temperature; Brain; Dopamine; Exploratory Behavior; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reward; Serotonin; Serotonin Agents; Time Factors

2002
Rewarding effects of the optical isomers of 3,4-methylenedioxy-methylamphetamine ('Ecstasy') and 3,4-methylenedioxy-ethylamphetamine ('Eve') measured by conditioned place preference in rats.
    Neuroscience letters, 2002, Sep-27, Volume: 330, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Hallucinogens; Isomerism; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Social Isolation

2002
Effects of MDMA exposure on the conditioned place preference produced by other drugs of abuse.
    Psychopharmacology, 2003, Volume: 166, Issue:4

    Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Psychological; Drug Interactions; Ethanol; Hallucinogens; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reward

2003
Methylphenidate and MDMA adolescent exposure in mice: long-lasting consequences on cocaine-induced reward and psychomotor stimulation in adulthood.
    Neuropharmacology, 2003, Volume: 45, Issue:1

    Topics: Age Factors; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Male; Methylphenidate; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Psychomotor Performance; Reward; Substance Withdrawal Syndrome; Time Factors; Weight Gain

2003
The rewarding properties of MDMA are preserved in mice lacking mu-opioid receptors.
    The European journal of neuroscience, 2004, Volume: 20, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Avoidance Learning; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Homovanillic Acid; Mice; Mice, Inbred Strains; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Receptors, Opioid, mu; Reward; Species Specificity; Time Factors

2004
Differential effects of amphetamines-induced neurotoxicity on appetitive and aversive Pavlovian conditioning in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:6

    Topics: Amphetamines; Animals; Antimanic Agents; Appetitive Behavior; Avoidance Learning; Central Nervous System Stimulants; Conditioning, Classical; Dopamine; Fenfluramine; Hallucinogens; Lithium Chloride; Male; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Neurotoxicity Syndromes; Receptors, Serotonin; Reinforcement, Psychology; Reward; Serotonin

2005
Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats.
    Addiction biology, 2005, Volume: 10, Issue:3

    Topics: Amphetamine; Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Feeding Behavior; Locomotion; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pyridines; Rats; Rats, Sprague-Dawley; Reward; Serotonin Agents

2005
Rewarding effects of 3,4-methylenedioxymethamphetamine ("Ecstasy") in dominant and subordinate OF-1 mice in the place preference conditioning paradigm.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Agonistic Behavior; Animals; Conditioning, Operant; Corticosterone; Dominance-Subordination; Gene Expression; Genes, fos; Immunohistochemistry; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Serotonin Agents; Social Environment; Stress, Psychological; Testosterone

2007
High ambient temperature increases 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")-induced Fos expression in a region-specific manner.
    Neuroscience, 2007, Mar-16, Volume: 145, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Biomarkers; Body Temperature; Body Temperature Regulation; Brain; Emotions; Fever; Hypothalamus; Limbic System; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward

2007
Rewarding effects and reinstatement of MDMA-induced CPP in adolescent mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:8

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Biogenic Amines; Brain Chemistry; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reinforcement Schedule; Reward

2007
3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice.
    Biological psychiatry, 2007, Sep-15, Volume: 62, Issue:6

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Dopamine; Extracellular Space; Hallucinogens; Injections, Intravenous; Male; Mice; Mice, Knockout; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Prefrontal Cortex; Reinforcement, Psychology; Reward; Self Administration; Serotonin; Serotonin Plasma Membrane Transport Proteins

2007
Behavioural and neurochemical effects of combined MDMA and THC administration in mice.
    Psychopharmacology, 2007, Volume: 195, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Hallucinogens; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Reinforcement, Psychology; Reward; Self Administration

2007
Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain.
    Neurotoxicology, 2007, Volume: 28, Issue:6

    Topics: Age Factors; Aging; Animals; Autoradiography; Behavior, Animal; Brain; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Exploratory Behavior; Impulsive Behavior; Locomotion; Male; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Time Factors

2007
The effects of concurrent administration of +/-3,4-methylenedioxymethamphetamine and cocaine on conditioned place preference in the adult male rat.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 88, Issue:2

    Topics: Animals; Body Weight; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Serotonin

2007
Long-term compulsive exercise reduces the rewarding efficacy of 3,4-methylenedioxymethamphetamine.
    Behavioural brain research, 2008, Feb-11, Volume: 187, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Blotting, Western; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Physical Conditioning, Animal; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward

2008
Impulsivity in Hong Kong-Chinese club-drug users.
    Drug and alcohol dependence, 2008, May-01, Volume: 95, Issue:1-2

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Asian People; Cross-Cultural Comparison; Cross-Sectional Studies; Drive; Exploratory Behavior; Female; Hong Kong; Humans; Illicit Drugs; Impulsive Behavior; Ketamine; Male; Marijuana Abuse; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Personality Inventory; Psychometrics; Punishment; Reproducibility of Results; Reward; Social Environment; Social Facilitation; Substance-Related Disorders

2008
Sub-chronic nandrolone treatment modifies neurochemical and behavioral effects of amphetamine and 3,4-methylenedioxymethamphetamine (MDMA) in rats.
    Behavioural brain research, 2008, May-16, Volume: 189, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Anabolic Agents; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nandrolone; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Serotonin; Statistics, Nonparametric

2008
Reward-related decision-making deficits and elevated impulsivity among MDMA and other drug users.
    Drug and alcohol dependence, 2008, Jul-01, Volume: 96, Issue:1-2

    Topics: Adult; Alcohol Drinking; Amphetamine-Related Disorders; Cognition Disorders; Control Groups; Decision Making; Female; Gambling; Humans; Impulsive Behavior; Male; N-Methyl-3,4-methylenedioxyamphetamine; Personality; Personality Inventory; Reward; Substance-Related Disorders; Surveys and Questionnaires

2008
Intracranial self-administration of MDMA into the ventral striatum of the rat: differential roles of the nucleus accumbens shell, core, and olfactory tubercle.
    Psychopharmacology, 2008, Volume: 198, Issue:2

    Topics: Animals; Behavior, Animal; Dopamine; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Nucleus Accumbens; Olfactory Bulb; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration

2008
Auditory stimuli enhance MDMA-conditioned reward and MDMA-induced nucleus accumbens dopamine, serotonin and locomotor responses.
    Brain research bulletin, 2008, Oct-22, Volume: 77, Issue:4

    Topics: Acoustic Stimulation; Animals; Auditory Perception; Conditioning, Operant; Dopamine; Environment; Hallucinogens; Locomotion; Male; Music; N-Methyl-3,4-methylenedioxyamphetamine; Noise; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Serotonin; Space Perception

2008
Effects of ethanol and ecstasy on conditioned place preference in the rat.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:2

    Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Psychological; Drug Interactions; Ethanol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Long-Evans; Reward; Serotonin Agents

2010
Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice.
    British journal of pharmacology, 2010, Volume: 159, Issue:1

    Topics: Animals; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Piperidines; Protein Kinase C; Protein Kinase Inhibitors; Reward; Time Factors

2010
Effects of repeated MDMA administration on the motivation for palatable food and extinction of operant responding in mice.
    Psychopharmacology, 2010, Volume: 208, Issue:4

    Topics: Animals; Conditioning, Operant; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Extinction, Psychological; Food; Male; Mice; Mice, Inbred Strains; Motivation; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Psychomotor Performance; Radioligand Assay; Radionuclide Imaging; Reinforcement Schedule; Reward; Rotarod Performance Test; Tritium

2010
Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice.
    Behavioral and brain functions : BBF, 2010, Mar-22, Volume: 6

    Topics: Animals; Behavior, Animal; Benzoxazines; Brain Chemistry; Calcium Channel Blockers; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Male; Mice; Mice, Inbred Strains; Morpholines; N-Methyl-3,4-methylenedioxyamphetamine; Naphthalenes; Neuroprotective Agents; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Serotonin Agents

2010
The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:4

    Topics: Animals; Anxiety; Astrocytes; Behavior, Animal; Body Temperature; Central Nervous System Stimulants; Conditioning, Operant; Corpus Striatum; Dopamine; Inflammation Mediators; Mice; Mice, Knockout; Microglia; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration

2011
Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA.
    Physiology & behavior, 2011, Jul-06, Volume: 103, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Outbred Strains; Cerebral Cortex; Choice Behavior; Conditioning, Psychological; Corpus Striatum; Corticosterone; Dopamine; Drug Administration Schedule; Drug Interactions; Ethanol; Extinction, Psychological; Hippocampus; Hydroxyindoleacetic Acid; Illicit Drugs; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Serotonin

2011
Rats preexposed to MDMA display attenuated responses to its aversive effects in the absence of persistent monoamine depletions.
    Psychopharmacology, 2011, Volume: 216, Issue:3

    Topics: Amphetamine-Related Disorders; Animals; Biogenic Monoamines; Caudate Nucleus; Conditioning, Psychological; Dose-Response Relationship, Drug; Frontal Lobe; Male; N-Methyl-3,4-methylenedioxyamphetamine; Putamen; Rats; Rats, Sprague-Dawley; Reward; Taste Perception

2011
Reward sensitivity and outcome expectancies as predictors of ecstasy use in young adults.
    Addictive behaviors, 2011, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Australia; Female; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Punishment; Reinforcement, Psychology; Reward; Substance-Related Disorders; Surveys and Questionnaires; Young Adult

2011
Active and passive MDMA ('ecstasy') intake induces differential transcriptional changes in the mouse brain.
    Genes, brain, and behavior, 2012, Volume: 11, Issue:1

    Topics: Adaptation, Physiological; Age Factors; Animals; Basal Ganglia; Brain; Conditioning, Operant; Drug-Seeking Behavior; Frontal Lobe; Gene Expression Regulation; Hallucinogens; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Raphe Nuclei; Reward; Self Administration; Tissue Distribution; Transcriptome

2012
Modulatory effects of low-dose MDMA on cocaine-induced locomotor activity and place conditioning in rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:3

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Serotonin Agents

2012
Adolescent pre-exposure to ethanol and 3,4-methylenedioxymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug-induced reinstatement.
    Addiction biology, 2012, Volume: 17, Issue:3

    Topics: Animals; Biogenic Amines; Central Nervous System Depressants; Cerebral Cortex; Conditioning, Psychological; Corpus Striatum; Ethanol; Extinction, Psychological; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Serotonin Agents

2012
Pharmacological characterization of 50-kHz ultrasonic vocalizations in rats: comparison of the effects of different psychoactive drugs and relevance in drug-induced reward.
    Neuropharmacology, 2012, Volume: 63, Issue:2

    Topics: Animals; Central Nervous System Stimulants; Male; Methylphenidate; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reward; Vocalization, Animal

2012
Differential alteration of the effects of MDMA (ecstasy) on locomotor activity and cocaine conditioned place preference in male adolescent rats by social and environmental enrichment.
    Psychopharmacology, 2012, Volume: 224, Issue:1

    Topics: Age Factors; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Hallucinogens; Housing, Animal; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Social Environment; Social Isolation

2012
Neurochemical substrates of MDMA reward: effects of the inhibition of serotonin reuptake on the acquisition and reinstatement of MDMA-induced CPP.
    Current pharmaceutical design, 2013, Volume: 19, Issue:40

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin

2013
Involvement of 5-hydroxytryptamine 5-HT₃ serotonergic receptors in the acquisition and reinstatement of the conditioned place preference induced by MDMA.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Animals; Biogenic Amines; Conditioning, Psychological; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Serotonin, 5-HT3; Reward; Spatial Behavior

2013
Effects of risperidone on the acquisition and reinstatement of the conditioned place preference induced by MDMA.
    Brain research bulletin, 2013, Volume: 98

    Topics: Age Factors; Animals; Animals, Newborn; Antipsychotic Agents; Conditioning, Psychological; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Risperidone; Serotonin Plasma Membrane Transport Proteins

2013
Higher sensitivity to the conditioned rewarding effects of cocaine and MDMA in High-Novelty-Seekers mice exposed to a cocaine binge during adolescence.
    Psychopharmacology, 2015, Volume: 232, Issue:1

    Topics: Age Factors; Animals; Cocaine; Conditioning, Psychological; Exploratory Behavior; Male; Maze Learning; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward

2015
Effects of acute social stress on the conditioned place preference induced by MDMA in adolescent and adult mice.
    Behavioural pharmacology, 2014, Volume: 25, Issue:5-6

    Topics: Aging; Animals; Anxiety; Conditioning, Psychological; Corticosterone; Dominance-Subordination; Dose-Response Relationship, Drug; Hallucinogens; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Social Behavior; Space Perception; Stress, Psychological

2014
Cocaine enhances the conditioned rewarding effects of MDMA in adolescent mice.
    Brain research bulletin, 2015, Volume: 113

    Topics: Animals; Biogenic Monoamines; Cocaine; Conditioning, Psychological; Drug Synergism; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward

2015
Oxytocin and MDMA ('Ecstasy') enhance social reward in rats.
    Psychopharmacology, 2015, Volume: 232, Issue:14

    Topics: Animals; Anxiety; Arginine Vasopressin; Conditioning, Operant; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Rats; Rats, Long-Evans; Reward; Serotonin Agents; Social Behavior

2015
Abuse potential of methylenedioxymethamphetamine (MDMA) and its derivatives in zebrafish: role of serotonin 5HT2-type receptors.
    Psychopharmacology, 2016, Volume: 233, Issue:15-16

    Topics: Amphetamines; Animals; Behavior, Animal; Conditioning, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Female; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Serotonin, 5-HT2; Reinforcement, Psychology; Reward; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Zebrafish

2016
Role of nitric oxide pathway in the conditioned rewarding effects of MDMA in mice.
    Behavioural brain research, 2017, 07-14, Volume: 330

    Topics: Animals; Central Nervous System Stimulants; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Hallucinogens; Indazoles; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nitric Oxide; Nitric Oxide Synthase; Reward

2017
Role of AMPA glutamate receptors in the conditioned rewarding effects of MDMA in mice.
    Behavioural brain research, 2018, 07-16, Volume: 347

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine-Related Disorders; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, AMPA; Reward; Spatial Behavior

2018
Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice.
    The European journal of neuroscience, 2019, Volume: 50, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Social Behavior; Stress, Psychological

2019
Synthetic cathinones and their phenethylamine analogues produce distinct psychomotor and reward behavior in crayfish.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Alkaloids; Amphetamines; Animals; Astacoidea; Behavior, Animal; Central Nervous System Sensitization; Central Nervous System Stimulants; Conditioning, Psychological; Male; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines; Reward

2020
Distinct neural mechanisms for the prosocial and rewarding properties of MDMA.
    Science translational medicine, 2019, 12-11, Volume: 11, Issue:522

    Topics: Animals; Brain; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Male; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Receptors, Oxytocin; Receptors, Serotonin; Reward; Serotonin Plasma Membrane Transport Proteins; Social Behavior

2019
Enhancement of the rewarding effects of 3,4-methylenedioxymethamphetamine in orexin knockout mice.
    Behavioural brain research, 2021, 01-01, Volume: 396

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Gyrus Cinguli; Male; Methamphetamine; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Orexins; Reward; Serotonin 5-HT1 Receptor Agonists; Spatial Learning

2021
Increased Response to 3,4-Methylenedioxymethamphetamine (MDMA) Reward and Altered Gene Expression in Zebrafish During Short- and Long-Term Nicotine Withdrawal.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Conditioning, Classical; Female; Gene Expression Regulation; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Receptors, Dopamine; Receptors, Oxytocin; Receptors, Purinergic P1; Reward; RNA, Messenger; Substance Withdrawal Syndrome; Swimming; Time Factors; Zebrafish

2021
Role of acute social stress in the rewarding effects of MDMA in adolescent mice.
    Behavioural brain research, 2021, 07-23, Volume: 410

    Topics: Age Factors; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Social Defeat; Stress, Psychological

2021