n-methyl-3,4-methylenedioxyamphetamine and oxytocin

n-methyl-3,4-methylenedioxyamphetamine has been researched along with oxytocin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (20.00)29.6817
2010's21 (70.00)24.3611
2020's3 (10.00)2.80

Authors

AuthorsStudies
Cowan, DA; Fallon, JK; Forsling, ML; Hutt, AJ; Kicman, AT; Shah, D; Tilbrook, GS1
Aitchison, KJ; Forsling, ML; Hartley, D; Holt, D; Tsapakis, EM; Winstock, AR; Wolff, K1
Arra, M; Emanuele, E; Pesenti, S1
Callaghan, PD; Cornish, JL; Hunt, GE; McGregor, IS; Thompson, MR1
Callaghan, PD; Hunt, GE; McGregor, IS1
Buitelaar, JK; Donders, AR; Dumont, GJ; Hermsen, R; Sweep, FC; Touw, DJ; van der Steen, R; van Gerven, JM; Verkes, RJ1
Arnold, JC; Hunt, GE; Long, LE; McGregor, IS; van Nieuwenhuijzen, PS1
Beringer, K; Broadbear, JH; Tunstall, B1
Callaghan, PD; Cornish, JL; Hunt, GE; McGregor, IS1
Bowen, MT; McGregor, IS1
Domes, G; Hysek, CM; Liechti, ME1
Adnum, L; Lock, J; Parrott, A; Thome, J1
Aitchison, K; Wolff, K1
Caminer, A; Hicks, C; Kassiou, M; Kevin, R; McGregor, IS; Narlawar, R; Ramos, L1
Domes, G; Eisenegger, C; Heinrichs, M; Hysek, CM; Liechti, ME; Preller, KH; Quednow, BB; Schmid, Y; Simmler, LD1
de Wit, H; Jacob, S; Kirkpatrick, MG; Lee, R; Wardle, MC1
Roberts, ID; Way, BM1
de Wit, H; Francis, SM; Jacob, S; Kirkpatrick, MG; Lee, R1
de la Torre, R; Dziobek, I; Farre, M; Kuypers, KP; Ramaekers, JG; Van den Bos, W; Yubero-Lahoz, S1
Crockett, MJ; Hysek, CM; Liechti, ME; Quednow, BB; Schmid, Y; Simmler, LD1
Duthaler, U; Grouzmann, E; Hysek, CM; Liechti, ME; Rickli, A; Schaffner, A; Schmid, Y1
Caminer, A; Goodwin, J; Hicks, C; McGregor, IS; Ramos, L1
de Wit, H; Francis, SM; Jacob, S; Kirkpatrick, MG1
Parrott, AC1
Dolder, PC; Kuypers, KPC; Liechti, ME; Ramaekers, JG1
Baumgartner, MR; Dziobek, I; Kraemer, T; Quednow, BB; Seifritz, E; Treichler, L; Vonmoos, M; Wunderli, MD; Zeller, C1
Liechti, ME; Vizeli, P1
Agurto, C; Baggott, MJ; Bedi, G; Cecchi, GA; Kirkpatrick, M; Norel, R; Ostrand, R; Wardle, MC; Wit, H1
Atila, C; Christ-Crain, M; Eckert, A; Heinrichs, M; Holze, F; Hutter, N; Liechti, ME; Murugesu, R; Rommers, N; Sailer, CO; Varghese, N1
de Wit, H; Lee, R; Lyubomirsky, S; Molla, H1

Reviews

3 review(s) available for n-methyl-3,4-methylenedioxyamphetamine and oxytocin

ArticleYear
From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long-term adverse consequences of drug use?
    British journal of pharmacology, 2008, Volume: 154, Issue:2

    Topics: Adaptation, Physiological; Adaptation, Psychological; Amphetamine-Related Disorders; Animals; Behavior, Addictive; Brain; Central Nervous System Stimulants; Dopamine; Humans; Limbic System; N-Methyl-3,4-methylenedioxyamphetamine; Neuropeptides; Oxytocin; Reinforcement, Psychology; Social Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

2008
Breaking the loop: oxytocin as a potential treatment for drug addiction.
    Hormones and behavior, 2012, Volume: 61, Issue:3

    Topics: Adaptation, Psychological; Alcoholism; Animals; Drug Tolerance; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Reward; Self Administration; Social Behavior; Social Environment; Substance Withdrawal Syndrome; Substance-Related Disorders

2012
Oxytocin, cortisol and 3,4-methylenedioxymethamphetamine: neurohormonal aspects of recreational 'ecstasy'.
    Behavioural pharmacology, 2016, Volume: 27, Issue:8

    Topics: Animals; Hallucinogens; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Pituitary-Adrenal System; Stress, Psychological

2016

Trials

11 trial(s) available for n-methyl-3,4-methylenedioxyamphetamine and oxytocin

ArticleYear
Increased oxytocin concentrations and prosocial feelings in humans after ecstasy (3,4-methylenedioxymethamphetamine) administration.
    Social neuroscience, 2009, Volume: 4, Issue:4

    Topics: Adolescent; Cross-Over Studies; Double-Blind Method; Emotions; Female; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Social Behavior; Young Adult

2009
MDMA enhances "mind reading" of positive emotions and impairs "mind reading" of negative emotions.
    Psychopharmacology, 2012, Volume: 222, Issue:2

    Topics: Adolescent; Adult; Double-Blind Method; Emotions; Empathy; Eye; Facial Expression; Female; Hallucinogens; Humans; Hydrocortisone; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Prospective Studies; Psychomotor Performance; Reaction Time; Young Adult

2012
MDMA enhances emotional empathy and prosocial behavior.
    Social cognitive and affective neuroscience, 2014, Volume: 9, Issue:11

    Topics: Adult; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Emotions; Empathy; Face; Female; Glycopeptides; Hallucinogens; Humans; Interpersonal Relations; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Pattern Recognition, Visual; Social Behavior; Visual Analog Scale; Young Adult

2014
Effects of MDMA and Intranasal oxytocin on social and emotional processing.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:7

    Topics: Administration, Intranasal; Adult; Blood Pressure; Choice Behavior; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Female; Hallucinogens; Heart Rate; Humans; Linear Models; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Social Behavior; Surveys and Questionnaires; Time Factors; Young Adult

2014
Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans.
    Psychoneuroendocrinology, 2014, Volume: 46

    Topics: Administration, Intranasal; Adolescent; Adult; Affect; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Serotonin Agents; Social Behavior; Young Adult

2014
No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT1a receptor activation.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Emotions; Empathy; Female; Humans; Interpersonal Relations; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Pindolol; Placebo Effect; Receptor, Serotonin, 5-HT1A; Substance-Related Disorders; Surveys and Questionnaires; Young Adult

2014
Differential effects of MDMA and methylphenidate on social cognition.
    Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Central Nervous System Stimulants; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Empathy; Epinephrine; Facial Expression; Female; Hallucinogens; Humans; Hydrocortisone; Judgment; Male; Methylphenidate; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Prolactin; Recognition, Psychology; Young Adult

2014
Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:1

    Topics: Adult; Bupropion; Cross-Over Studies; Dopamine; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Drug Interactions; Epinephrine; Female; Heart Rate; Humans; Hydrocortisone; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Oxytocin; Prolactin; Psychotropic Drugs; Young Adult

2015
Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Alleles; Empathy; Female; Genotype; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Polymorphism, Single Nucleotide; Receptors, Oxytocin; Social Behavior; Social Behavior Disorders; Young Adult

2018
Detection of acute 3,4-methylenedioxymethamphetamine (MDMA) effects across protocols using automated natural language processing.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:5

    Topics: Administration, Intranasal; Adult; Double-Blind Method; Female; Humans; Language; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Oxytocin; Psycholinguistics; Psychotropic Drugs; Semantics; Speech; Young Adult

2020
Oxytocin in response to MDMA provocation test in patients with arginine vasopressin deficiency (central diabetes insipidus): a single-centre, case-control study with nested, randomised, double-blind, placebo-controlled crossover trial.
    The lancet. Diabetes & endocrinology, 2023, Volume: 11, Issue:7

    Topics: Arginine; Case-Control Studies; Cross-Over Studies; Diabetes Insipidus, Neurogenic; Diabetes Mellitus; Double-Blind Method; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin

2023

Other Studies

16 other study(ies) available for n-methyl-3,4-methylenedioxyamphetamine and oxytocin

ArticleYear
The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus.
    British journal of pharmacology, 2002, Volume: 135, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Hypothalamus; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Pituitary Hormones, Posterior; Rats; Rats, Wistar; Serotonin Agents; Vasopressins

2002
Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population.
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Arginine Vasopressin; Arousal; Female; Homeostasis; Humans; Illicit Drugs; Inappropriate ADH Syndrome; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Radioimmunoassay; Social Environment; Social Facilitation; Substance-Related Disorders; Water-Electrolyte Balance

2006
Vasopressin and oxytocin as neurohormonal mediators of MDMA (ecstasy) sociosexual behavioural effects.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Arousal; Emotions; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Serotonin; Sexual Behavior; Social Behavior; Vasopressins

2006
A role for oxytocin and 5-HT(1A) receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine ("ecstasy").
    Neuroscience, 2007, May-11, Volume: 146, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Piperazines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior

2007
Residual social, memory and oxytocin-related changes in rats following repeated exposure to γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination.
    Psychopharmacology, 2010, Volume: 212, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Body Weight; Brain; Chromatography, High Pressure Liquid; Emotions; Gene Expression Regulation; Injections, Intraperitoneal; Male; Memory; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Oxytocin; Recognition, Psychology; RNA, Messenger; Social Behavior; Sodium Oxybate; Substance Withdrawal Syndrome; Time Factors

2010
Examining the role of oxytocin in the interoceptive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') using a drug discrimination paradigm in the rat.
    Addiction biology, 2011, Volume: 16, Issue:2

    Topics: Adrenergic Uptake Inhibitors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents, Tricyclic; Brain; Conditioning, Psychological; Cues; Discrimination Learning; Excitatory Amino Acid Antagonists; Female; Hormone Antagonists; Imipramine; Male; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Synaptic Transmission; Vasotocin

2011
MDMA-induced c-Fos expression in oxytocin-containing neurons is blocked by pretreatment with the 5-HT-1A receptor antagonist WAY 100635.
    Brain research bulletin, 2011, Aug-10, Volume: 86, Issue:1-2

    Topics: Animals; Behavior, Animal; Brain; Humans; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Oxytocin; Piperazines; Proto-Oncogene Proteins c-fos; Pyridines; Random Allocation; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists

2011
MDMA can increase cortisol levels by 800% in dance clubbers.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:1

    Topics: Arginine Vasopressin; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Female; Humans; Hydrocortisone; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Oxytocin; Polymorphism, Genetic; Substance-Related Disorders

2013
Reply to 'MDMA can increase cortical levels by 800% in dance clubbers' Parrott et al.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:1

    Topics: Arginine Vasopressin; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Female; Humans; Hydrocortisone; Hyponatremia; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Oxytocin; Polymorphism, Genetic; Substance-Related Disorders

2013
Acute prosocial effects of oxytocin and vasopressin when given alone or in combination with 3,4-methylenedioxymethamphetamine in rats: involvement of the V1A receptor.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:11

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Hallucinogens; Hormone Antagonists; Indoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Pyrrolidines; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Social Behavior; Vasopressins

2013
Using 'hug drugs' to understand affiliative behavior: the value of the social neurochemistry perspective. Commentary on: 'Ecstasy' as a social drug: MDMA preferentially affects responses to emotional stimuli with social content by Wardle, Kirkpatrick, and
    Social cognitive and affective neuroscience, 2014, Volume: 9, Issue:8

    Topics: Emotions; Female; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Social Behavior

2014
Oxytocin and MDMA ('Ecstasy') enhance social reward in rats.
    Psychopharmacology, 2015, Volume: 232, Issue:14

    Topics: Animals; Anxiety; Arginine Vasopressin; Conditioning, Operant; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Rats; Rats, Long-Evans; Reward; Serotonin Agents; Social Behavior

2015
Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration.
    Psychoneuroendocrinology, 2016, Volume: 74

    Topics: Administration, Intranasal; Adolescent; Adult; Autism Spectrum Disorder; Double-Blind Method; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropeptides; Neurotransmitter Agents; Oxytocin; Young Adult

2016
Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:5

    Topics: Adult; Double-Blind Method; Emotions; Empathy; Female; Hallucinogens; Healthy Volunteers; Humans; Interpersonal Relations; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Social Behavior; Young Adult

2017
Social Cognition and Interaction in Chronic Users of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy").
    The international journal of neuropsychopharmacology, 2018, 04-01, Volume: 21, Issue:4

    Topics: Adult; Decision Making; Empathy; Female; Humans; Illicit Drugs; Interpersonal Relations; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Oxytocin; Social Behavior; Social Perception; Young Adult

2018
Drug-induced social connection: both MDMA and methamphetamine increase feelings of connectedness during controlled dyadic conversations.
    Scientific reports, 2023, 09-22, Volume: 13, Issue:1

    Topics: Communication; Emotions; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin

2023