n-methyl-3,4-methylenedioxyamphetamine and 3,4-methylenedioxyamphetamine

n-methyl-3,4-methylenedioxyamphetamine has been researched along with 3,4-methylenedioxyamphetamine in 531 studies

Research

Studies (531)

TimeframeStudies, this research(%)All Research%
pre-1990124 (23.35)18.7374
1990's250 (47.08)18.2507
2000's105 (19.77)29.6817
2010's40 (7.53)24.3611
2020's12 (2.26)2.80

Authors

AuthorsStudies
Hoffman, AJ; Jacob, P; Nichols, DE; Oberlender, RA; Shulgin, AT1
Butler, SG; Cloonan, SM; Corrigan, D; Jørgensen, AM; Keating, JJ; Knox, AJ; Lloyd, DG; Meegan, MJ; Peters, GH; Rai, D; Williams, DC1
Cloonan, SM; Corrigan, D; Kavanagh, PV; Keating, JJ; Meegan, MJ; O'Brien, JE; Williams, DC1
Butler, SG; Cloonan, SM; Keating, JJ; Knox, AJ; McNamara, YM; Meegan, MJ; Peters, GH; Williams, DC1
Arunotayanun, W; Dalley, JW; Gibbons, S; Huang, XP; Iversen, L; Roth, BL; Setola, V; Treble, R1
Glennon, RA2
Goromaru, T; Hashimoto, K; Maeda, H2
Kaskey, GB1
Fahy, T; McGuire, P2
Cunningham, KA; Paris, JM2
Cairns, HS; Cohen, SL; Sarner, M; Screaton, GR; Singer, M; Thrasher, A1
Rudnick, G; Wall, SC1
Campkin, NT; Davies, UM1
Teggin, AF1
Elayan, I; Foltz, RL; Gibb, JW; Hanson, GR; Johnson, M; Lim, HK2
Callaway, CW; Geyer, MA2
Bravo, GL; Grob, CS; Liester, MB; Walsh, RN2
Bell, GM; Fahal, IH; Sallomi, DF; Yaqoob, M1
Henry, JA1
Dawling, S; Henry, JA; Jeffreys, KJ1
Hall, W; Lee, N; Solowij, N1
Lavies, NG; Singarajah, C1
Rittoo, D; Rittoo, DB2
Ellis, SJ1
Larner, AJ2
Geyer, MA; Paulus, MP1
Mazzi, D; Pallanti, S1
Clark, ML; Davies, SE; Gorard, DA1
Chapman, RW; Ryley, NG; Satsangi, J; Shearman, JD; Weatherhead, S1
De Silva, RN; Harries, DP1
Sawyer, J; Stephens, WP1
Nash, JF; Yamamoto, BK1
Azmitia, EC; Berger, UV; Gu, XF1
Lyttle, T; Montagne, M1
Garges, PL; Gordon, CJ; Miller, DB; Rezvani, AH1
Heninger, GR; Krystal, JH; Opsahl, C; Price, LH; Ricaurte, GA1
Bedford Russell, AR; Dawling, S; Schwartz, RH1
Callaway, CW; Geyer, MA; Peng, RY; Rempel, N1
Greer, G1
Lever, JR; Ricaurte, GA; Scheffel, U; Stathis, M1
Glennon, RA; Higgs, R1
McCann, UD; Ricaurte, GA4
Barrett, PJ2
Farfel, GM; Seiden, LS; Vosmer, GL1
Glennon, RA; Higgs, R; Issa, H; Young, R1
Fadayel, GM; Schmidt, CJ; Sullivan, CK; Taylor, VL1
Chei, DM; Foltz, RL; Lim, HK; Zeng, S1
Nakahara, Y; Shimamine, M; Takahashi, K1
Gibb, JW; Hanson, GR; Johnson, M; Mitros, K; Stone, DM; Zobrist, R1
Katz, JL; Martello, AL; Martello, MB; Ricaurte, GA1
Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R1
Katz, JL; Ricaurte, GA; Steele, TD1
Frescas, SP; Johnson, MP; Nichols, DE; Oberlender, R1
Montero, M; Prat, A; Reig, R; Sanz, P1
Winstock, AR1
Colpaert, FC; Millan, MJ1
Pan, HS; Wang, RY2
Gordon, CJ; Miller, DB; O'Callaghan, JP; Watkinson, WP1
Brewster, WK; Johnson, MP; Nichols, DE; Steele, TD; Yim, GK1
Andurkar, S; Clark, CR; DeRuiter, J; Noggle, FT1
Chadwick, IS; Curry, PD; Doran, B; Freemont, AJ; Linsley, A1
Aghajanian, GK; Bradberry, CW; Roth, RH; Sheldon, PW; Sprouse, JS1
Schechter, MD5
Garrett, ER; Marroum, P; Seyda, K1
Dragunow, M; Laverty, R; Logan, B1
Cho, AK; Kumagai, Y; Schmitz, DA; Wickham, KA1
Cho, AK; Fukuto, JM; Kumagai, Y1
Ali, SF; Chang, LW; Slikker, W1
Battaglia, G; de Souza, EB; Kuhar, MJ; Sharkey, J1
Brodkin, J; Nash, JF1
Schifano, F1
Bilsky, EJ; Reid, LD1
Kaminer, Y; Zemishlany, Z1
Azmitia, EC; Park, WK1
Benazzi, F; Mazzoli, M1
Kelly, PA; McBean, DE; Sharkey, J1
Boja, JW; Schechter, MD2
Black, DL; Creighton, FJ; Hyde, CE1
Conarty, PF; Johnson, MP; Nichols, DE1
Aghajanian, GK; Bradberry, CW; Roth, RH; Sprouse, JS3
Rattray, M1
Black, CK; Schmidt, CJ; Taylor, VL2
Foltz, RL; Lim, HK1
Bilsky, EJ; Delconte, JD; Hubbell, CL; Reid, LD1
Gudelsky, GA; Meltzer, HY; Nash, JF2
Cho, AK; Hiramatsu, M1
Goromaru, T; Hashimoto, K2
Gaylor, DW; Slikker, W2
Finnegan, KT; Irwin, I; Langston, JW; Ricaurte, GA1
Arora, RC; Meltzer, HY; Nash, JF; Schreiber, MA1
Ali, SF; Gough, B; Holson, RR; Slikker, W1
Hsu, FL; Yeh, SY1
Dornan, WA; Katz, JL; Ricaurte, GA1
Chang, AS; Cho, AK; DiStefano, E; Hiramatsu, M1
Huang, XM; Johnson, MP; Nichols, DE1
McKenna, DJ; Peroutka, SJ1
Culp, S; De Souza, EB; Zaczek, R1
Brewster, WK; Johnson, MP; Nichols, DE; Oberlender, R; Riggs, RM1
Geyer, MA; Gold, LH; Mandell, AJ; Paulus, MP1
Bravo, G; Grob, C; Walsh, R1
Azmitia, EC; Murphy, RB; Whitaker-Azmitia, PM1
Kimes, AS; London, ED; Ori, C; Wilkerson, G1
Virus, RM; Woolverton, WL; Zacny, JP1
Hekmatpanah, CR; Peroutka, SJ1
Evans, SM; Johanson, CE; Zacny, JP1
Peroutka, SJ; Wagner, J1
Insel, TR; Winslow, JT1
Callaway, CW; Geyer, MA; Wing, LL1
Cho, AK; Hiramatsu, M; Kumagai, Y; Unger, SE1
Schmidt, CJ; Taylor, VL3
Gibb, JW; Hanson, GR; Johnson, M3
Blanke, RV; Fitzgerald, RL; Glennon, RA; Narasimhachari, N; Rosecrans, JA; Yousif, MY1
Abbate, GM; Black, CK; Schmidt, CJ; Taylor, VL3
Gibb, JW; Hanson, GR; Johnson, M; Stone, D1
Nichols, DE; Oberlender, R4
Appel, NM; De Souza, EB; Glennon, RA; Leonhardt, S; Teitler, M1
Berger, UV; Mamounas, LA; Molliver, DC; Molliver, ME; O'Hearn, E; Wilson, MA1
Kehne, JH; Schmidt, CJ1
Battaglia, G; De Souza, EB; Insel, TR1
Lum, JT; Palmer, JR; Piercey, MF1
Nash, JF1
Ricaurte, GA; Scheffel, U1
Fitzgerald, JL; Reid, JJ2
Poland, RE1
Huang, XM; Johnson, MP; Nash, JF; Nichols, DE; Oberlender, R1
Bilsky, EJ; Hubbell, CL; Hui, YZ; Reid, LD1
Lovenberg, W; Schmidt, CJ; Wu, L1
Schmidt, CJ3
Battaglia, G; De Souza, EB; Kuhar, MJ; Molliver, ME; O'Hearn, E; Yeh, SY1
Gibb, JW; Hanson, GR; Stone, DM2
Gibb, JW; Hanson, GR; Stahl, DC; Stone, DM2
Battaglia, G; De Souza, EB; Yeh, SY1
DeLanney, LE; Forno, LS; Irwin, I; Langston, JW; Molliver, ME; Ricaurte, GA; Wilson, MA1
Ali, SF; Bailey, JR; Frith, CH; Newport, GD; Scallet, AC; Slikker, W1
Battaglia, G; De Souza, EB; Kuhar, MJ; Molliver, ME; O'Hearn, E1
DeLanney, LE; Irwin, I; Langston, JW; Ricaurte, GA; Wiener, SG1
Bush, LG; Gibb, JW; Hanson, GR; Johnson, M; Stone, DM1
Battaglia, G; De Souza, EB; Insel, TR; Johannessen, JN; Marra, S1
Gibb, JW; Hanson, GR; Johnson, M; Letter, AA; Merchant, K1
Kleven, MS; Seiden, LS; Woolverton, WL1
Lowy, MT; Meltzer, HY; Nash, JF1
Johnson, MP; Nichols, DE1
Bush, L; Gibb, JW; Hanson, GR; Johnson, M; Letter, A; Merchant, KM; Sonsalla, P1
Heninger, GR; Krystal, JH; Price, LH; Ricaurte, GA2
Aronson, TA; Whitaker-Azmitia, PM1
Peroutka, SJ2
Edwards, G1
Dimpfel, W; Nichols, DE; Spüler, M1
Barrett, JE; Hoffmann, SM; Nader, MA1
Blanke, RV; Fitzgerald, RL; Glennon, RA; Rosecrans, JA1
Laverty, R; Logan, BJ1
Gold, LH; Hubner, CB; Koob, GF1
Spanos, LJ; Yamamoto, BK2
London, ED; Wilkerson, G1
Hekmatpanah, CR; McKenna, DJ; Peroutka, SJ1
Cho, AK; Hiramatsu, M; Kameyama, T; Maeda, Y; Nabeshima, T1
Li, AA; Marek, GJ; Seiden, LS; Vosmer, G1
Finnegan, KT; Irwin, I; Langston, JW; Skratt, JJ1
Gold, LH; Koob, GF2
Chiodo, LA; Freeman, AS; Kelland, MD1
Cho, AK; Gazzara, RA; Howard, SG; Takeda, H1
Battaglia, G; De Souza, EB1
Culp, S; De Souza, EB; Hurt, S; Zaczek, R1
Ricaurte, GA1
Champney, TH; Frye, GD; Matthews, RT1
Glennon, RA; Misenheimer, BR1
Nichols, DE; Steele, TD; Yim, GK2
Boja, JW; Crisp, T; Schechter, MD; Stafinsky, JL1
Ali, SF; Gollamudi, R; Kolta, M; Leakey, JE; Lipe, G; Lopez, M; Newport, G; Slikker, W; Webb, P1
Ali, SF; Bailey, JR; Holson, RR; Hong, JS; Kolta, MG; McMillan, DE; Paule, MG; Scallet, AC; Scalzo, FM; Slikker, W1
Geyer, MA; Gold, LH; Koob, GF2
Cabrera, T; Hamilton, ME; Hata, N; Lorens, SA1
Whitaker-Azmitia, PM1
Greer, G; Strassman, RJ1
Mack, RB1
Gehlert, DR; Lovenberg, W; Schmidt, CJ; Wu, L1
Glennon, RA; Lyon, RA; Titeler, M1
Bakalar, JB; Grinspoon, L1
Beck, J; Morgan, PA1
Brady, JF; Cho, AK; Di Stefano, EW1
Johanson, CE; Kamien, JB; Schuster, CR; Woolverton, WL1
Balster, RL; Beardsley, PM; Harris, LS1
Evans, SM; Johanson, CE1
Hoffman, AJ; Johnson, MP; Nichols, DE1
Bost, RO; Dowling, GP; McDonough, ET1
Levin, JA; Lovenberg, W; Schmidt, CJ1
Davis, WM; Hatoum, HT; Waters, IW1
Griffiths, RR; Lamb, RJ1
Gibb, JW; Hanson, GR; Johnson, M; Stone, DM2
Commins, DL; Schuster, CR; Seiden, LS; Virus, RM; Vosmer, G; Woolverton, WL1
Mastropaolo, J; Thompson, DM; Winsauer, PJ1
Glennon, RA; Little, PJ; Rosecrans, JA; Yousif, M1
Rumack, BH; Smilkstein, MJ; Smolinske, SC1
DeLanney, LE; Finnegan, KF; Irwin, I; Langston, JW; Nichols, DE; Ricaurte, GA1
Brown, C; Osterloh, J1
Gibb, JW; Hanson, GR; Johnson, M; Letter, AA; Merchant, KM; Stone, DM1
Mokler, DJ; Robinson, SE; Rosecrans, JA1
Peroutka, SJ; Ricaurte, GA; Wang, SS1
Chang, LW; Doblin, R; Frith, CH; Hamm, J; Lattin, DL; Walls, RC1
Boja, JW; Kulmala, HK; Schechter, MD1
Glennon, RA; Rosecrans, JA1
Heym, J; Jacobs, BL1
Barnes, DM3
Alrazi, J; Jaffe, JH; Verebey, K1
Jacobson, AE1
Gibb, JW; Hanson, GR; Merchant, KM; Stone, DM1
Glennon, RA; Patrick, G; Yousif, M1
DeLanney, LE; Irwin, I; Langston, JW; Ricaurte, GA1
Fitzgerald, RL; Poklis, A; Ramos, JM1
Appler, WD; Beck, DC1
Bost, RO1
Finnegan, KT; Irwin, I; Langston, JW; Peroutka, SJ; Ricaurte, GA; Ritchie, LD1
Bird, M; Hubner, CB; Kornetsky, C; Rassnick, S1
Battaglia, G; Brooks, BP; De Souza, EB; Kulsakdinun, C1
Appel, JB; Callahan, PM1
Nencini, P; Seiden, LS; Woolverton, WL1
Ali, SF; Frith, CH; Holson, RR; Lipe, GW; Scallet, AC; Slikker, W1
Laverty, R; Logan, BJ; Sanderson, WD; Yee, YB1
Peroutka, SJ; Pierce, PA1
Bush, L; Gibb, JW; Hanson, GR; Letter, AA; Merchant, KM1
Harris, H; Newman, H; Peroutka, SJ1
Anderson, GM; Glennon, RA; Rosecrans, JA; Young, R1
Borne, RF; Davis, WM1
Cirimele, V; Kintz, P; Mangin, P; Tracqui, A1
Colado, MI; Green, AR1
McCann, UD; Ricaurte, GA; Ridenour, A; Shaham, Y1
Colado, MI; Green, AR; Williams, JL1
Hatzidimitriou, G; Katz, JL; Martello, AL; Ricaurte, GA; Scanzello, CR1
Colado, MI; Green, AR; Murray, TK1
Hashimoto, K1
Baum, I; Cadet, JL; Carlson, E; Epstein, C; Ladenheim, B1
Brodkin, JD; Gudelsky, GA; Nash, JF; Nichols, DE; Roth, BL1
Barrios-Zambrano, L; Bronson, ME; Clark, CR; DeRuiter, J; Jiang, W; Newland, MC1
Cowie, JS; Oon, MC; Renton, RJ1
Allen, RP; McCann, UD; Ricaurte, GA1
Blyth, AS; Dougall, JR; Kennedy, BW; Nimmo, SM; Tullett, WM1
Hewitson, H; Logan, AS; O'Keefe, N; Stickle, B1
Atrens, DM; Christie, MJ; Jackson, DM; Lin, HQ; McGregor, IS2
Rudnick, G; Schuldiner, S; Steiner-Mordoch, S; Wall, SC; Yelin, R1
Henry, JA; Maxwell, DL; Polkey, MI1
George, WJ; Michel, RE; Rege, AB1
Coakley, JH; Ferguson, C; Hinds, CJ; Skinner, R; Watson, JD1
de Olmos, JS; Haykal-Coates, N; Jensen, KF; Miller, DB; O'Callaghan, J; Olin, J1
Cho, AK; Hiramatsu, M; Kumagai, Y; Patel, N1
Connolly, MJ; Manchanda, S1
Evans, RJ; Hughes, JC; McCabe, M1
Cho, AK; Hiratsuka, A; Kumagai, Y; Lin, LY; Narimatsu, S; Oguri, K; Suzuki, T; Yamada, H; Yoshimura, H1
Dart, JK; O'Neill, D1
Kessel, B1
Fadayel, GM; Schmidt, CJ; Sullivan, CK1
Lee, JW1
Harvey, JA; Romano, AG1
Padkin, A1
Clark, JC; Forrest, AR; Galloway, JH; Marsh, ID; Strachan, GA1
Cho, AK; Chu, TY; Ellis, SW; Hiratsuka, A; Lennard, MS; Lin, LY; Schmitz, DA; Tucker, GT; Woods, HF1
Carr, AA; Fadayel, GM; Humphreys, TM; Kehne, JH; Kettler, HJ; McCloskey, TC; Padich, RA; Schmidt, CJ; Sorensen, SM; Taylor, VL1
Arends, JW; Oranje, WA; Stockbrügger, RW; vd Wurff, A; von Pol, P; Zeijen, RN1
Azmitia, EC; Kramer, K; Whitaker-Azmitia, PM1
McCann, UD; Ricaurte, GA; Steele, TD1
Bronson, ME; Clark, CR; DeRuiter, J; Jiang, W1
Cuomo, MJ; Dyment, PG; Gammino, VM1
Dasgupta, A; Thompson, WC1
Fogelson, L; Gordon, CJ1
Marona-Lewicka, D; Nichols, DE1
Borchardt, D; Gouzoulis, E; Hermle, L1
Castañeda, E; Robinson, TE; Whishaw, IQ1
Campkin, NJ; Davies, UM1
Stone, RJ1
Tehan, B1
Galligan, P; Meagher, D; Williams, H1
Calder, L; Clikeman, J; Finnegan, KT; Karler, R; Wei, S1
Castagna, F; Ferrara, SD; Frison, G; Giorgetti, R; Tedeschi, L1
de Man, RA; Tjen, HS; Wilson, JH1
Goromaru, T; Hashimoto, K; Hirai, K; Maeda, H1
Fitzgerald, RL; Hall, KV; Poklis, A; Saady, JJ1
Drew, S; Levine, AJ; Rees, GM1
Barrett, PJ; Taylor, GT1
Callaway, CW; Geyer, MA; Rempel, NL1
Cadier, MA; Clarke, JA1
Miller, DB; O'Callaghan, JP1
Morano, RA; Plank, SM; Spies, C; Walker, FB1
Schwartz, RH1
Azmitia, EC; Gu, XF1
Webb, C; Williams, V1
Brodkin, J; Malyala, A; Nash, JF1
Duxbury, AJ1
Cox, DE1
Hatzidimitriou, G; Markowska, AL; Olton, DS; Ricaurte, GA; Wenk, GL; Wlos, J1
Foltz, RL; Lim, HK; Su, Z1
Lindefors, N; Series, H1
Bush, LG; Gibb, JW; Hanson, GR; Johnson, M1
Böning, J; Wodarz, N1
Gordon, CJ; Watkinson, WP1
Blaschke, G; Bohn, G; Bohn, M1
Huang, X; Nichols, DE1
Grant, R; Rothwell, PM1
Bell, D; Gledhill, JA; Henry, JA; Moore, DF1
Baker, GB; Coutts, RT; Hegadoren, KM1
Cho, AK; Chu, T; DiStefano, EW; Kumagai, Y1
Clark, JC; Forrest, AR; Milroy, CM1
Cox, DE; Williams, KR1
Brown, ER; Jarvie, DR; Simpson, D1
Fineschi, V; Masti, A1
Tucker, G1
Kauert, G; Röhrich, J1
Bourquin, D; Bracher, K; Brenneisen, R; Helmlin, HJ; Vonlanthen, D1
Kronstrand, R1
Gouzoulis-Mayfrank, E; Hermle, L; Kovar, KA; Sass, H1
Fierro, MF; Moore, KA; Mozayani, A; Poklis, A1
Barni Comparini, I; Centini, F; Masti, A1
Cirimele, V; Kintz, P1
Kikura, R; Mieczkowski, T; Nakahara, Y; Tagliaro, F1
Barrio Anta, G; de la Fuente de Hoz, L; Rodríguez Arenas, MA; Sánchez Payá, J; Vicente Orta, J1
Brenneisen, R; Lanz, M; Thormann, W1
Murthy, BV; Roberts, NB; Wilkes, RG1
Baker, LE; Taylor, MM1
Hall, AP1
Sadeghipour, F; Veuthey, JL1
Dirnhofer, R; Keller, T; Miki, A; Regenscheit, P; Schneider, A; Tsuchihashi, H1
Tretter, F1
Kovar, KA1
Krieg, JC; Mennel, HD; Schäfer, T; Schlegel, J; Stumm, G; Vedder, H; Würz, C1
Camí, J; de la Torre, R; Farré, M; Mas, M; Ortuño, J; Roset, PN; Segura, J1
Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E1
Felgenhauer, N; Zilker, T1
Cody, JT; Hensley, D1
Centini, F; Fineschi, V; Mazzeo, E; Turillazzi, E1
Atterwill, CK; Davenport-Jones, JE; Fox, RM; Walker, TM1
Brenneisen, R; Camí, J; de la Torre, R; Farré, M; Mas, M; Ortuño, J; Roset, PN; Segura, J1
Aguirre, N; Barrionuevo, M; Del Río, JD; Lasheras, B1
Allen, DL; Oliver, JS1
Krogh, M; Rasmussen, KE; Ugland, HG1
Connor, TJ; Kelly, JP; Leonard, BE1
Dulawa, SC; Geyer, MA; Hen, R; Scearce-Levie, KA1
Dawson, M; Kannangara, GS; Lee, GS; Taylor, RC; Wilson, MA1
Clauwaert, KM; De Leenheer, AP; De Letter, EA; Lambert, WE; Van Bocxlaer, JF; Van Calenbergh, S1
Backofen, U; Hoffmann, W; Lunte, CE; Matysik, FM1
Brunnenberg, M; Kovar, KA1
Bo, J; Huang, Z; Liu, W; Shen, B; Shen, M; Xiang, P; Yan, W1
Boland, G; Kelly, JP; O'Boyle, KM; O'Loinsigh, ED1
Campíns-Falcó, P; Herráez-Hernández, R; Verdú-Andrés, J1
Bai, F; Jones, DC; Lau, SS; Monks, TJ2
de la Torre, R; Farré, M; Navarro, M; Ortuño, J; Pichini, S; Roset, PN; Segura, J1
Clauwaert, KM; De Leenheer, AP; Van Bocxlaer, JF1
Brehm, G; Sägmüller, B; Schneider, S; Schwarze, B1
Bai, F; Lau, SS; Miller, RT; Monks, TJ1
Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; O'Shea, E1
Clauwaert, KM; De Leenheer, AP; De Letter, EA; Lambert, WE; Piette, MH; Van Bocxlaer, JF1
Dams, R; De Leenheer, AP; De Letter, EA; Lambert, WE; Mortier, KA; Van Calenbergh, S1
Camí, J; de la Torre, R; Farré, M; Hernández-López, C; Joglar, J; Llebaria, A; Mas, M; Ortuño, J; Pizarro, N; Pujadas, M; Roset, PN; Segura, J1
Barnett, DA; Ells, B; Guevremont, R; McCooeye, MA; Mester, Z; Purves, RW1
Carter, JF; Murray, M; Sleeman, R; Titterton, aE1
Kovar, KA; Mayerhofer, A; Meyer, A; Schmidt, WJ2
Clauwaert, KM; Craeymeersch, ME; Dams, R; De Letter, EA; Espeel, MF; Lambert, WE; Mortier, KA; Piette, MH1
Banks, ML; Cook, VJ; Mills, EM; Sprague, JE1
Cole, JC; Sumnall, HR1
Cooper, DP; De Boeck, G; De Bruijn, EA; Maes, RA; Morris, M; Samyn, N; Wood, M1
Blough, B; Glennon, RA; Grande-Allen, KJ; Hufeisen, SJ; Roth, BL; Rothman, RB; Setola, V; Vesely, I1
Kovar, KA; Lebsanft, HB; Mayerhofer, A; Schmidt, WJ1
Huang, Z; Zhang, S1
García-Repetto, R; Giménez, MP; Jurado, C; Menéndez, M; Moreno, E; Soriano, T1
Cleary, L; Docherty, JR1
Easton, N; Fry, J; Kingston, S; Marsden, CA; O'Shea, E; Watkins, A1
Cobain, K; Corkery, J; Ghodse, AH; Jambert-Gray, R; Martinotti, G; Oyefeso, A; Schifano, F1
Dumasia, MC1
Boothby, LA; Chronister, CW; Doering, PL; Goldberger, BA; McCusker, RR; Merves, ML; Murray, RA1
Haefeli, WE; Ketabi-Kiyanvash, N; Mikus, G; Weiss, J1
Horn, CK; Klette, KL; Stout, PR1
Parrott, AC1
Bouche, MP; De Letter, EA; Lambert, WE; Piette, MH; Van Bocxlaer, JF1
Katagi, M; Miki, A; Shima, N; Tsuchihashi, H1
Jones, DC; Lau, SS; Monks, TJ1
Freudenmann, RW; Spitzer, M1
Bassetto, F; Castagna, F; Dall'Olio, G; Marchioro, L; Plebani, M; Tedeschi, L1
da Costa, JL; da Matta Chasin, AA1
Hugel, J; Kalasinsky, KS; Kish, SJ1
Jacobs, A; Jemionek, J; Lesser, D; Paul, BD; Searles, DA1
De Boeck, G; Laloup, M; Maes, V; Ramaekers, J; Samyn, N; Tilman, G; Wallemacq, P1
Chung, H; Han, E; Kim, E; Lee, J; Lim, M; Park, Y; Yang, W1
Concheiro, M; Cruz, A; de Castro, A; López-Rivadulla, M; Quintela, O1
Hatzidimitriou, G; Irvine, RJ; McCann, UD; Mechan, A; Ricaurte, GA; Yuan, J1
de Boeck, G; Kraemer, T; Lamers, CT; Maurer, HH; Peters, FT; Riedel, WJ; Samyn, N1
Grubwieser, P; Libiseller, K; Pavlic, M; Rabl, W2
Huang, YS; Lin, CH; Liu, JT; Tsai, CC1
Harkin, A; Kerans, A; McNamara, R; O'Neill, B1
Carney, B; Gillespie, J; Mc Fadden, K; O'Driscoll, D1
Bexis, S; Docherty, JR1
Corkery, J; Deluca, P; Ghodse, AH; Oyefeso, A; Schifano, F1
Jeng, W; Parman, T; Ramkissoon, A; Wells, PG1
Johansen, SS; Olsen, KH; Rasmussen, LB1
Abraham, TT; Huestis, MA; Pirnay, SO1
Crean, RD; Davis, SA; Katner, SN; Lay, CC; Taffe, MA; Von Huben, SN1
Nakashima, K; Nakashima, MN; Tomita, M; Wada, M2
Lin, DL; Liu, HC; Liu, RH1
Abraham, TT; Huestis, MA; Lowe, RH; Pirnay, SO1
Martins, LF; Ramaekers, JG; Samyn, N; Wennig, R; Yegles, M1
de la Torre, R; Di Giovannandrea, R; Jurado, C; Langohr, K; Pacifici, R; Pichini, S; Pujadas, M; Ventura, M; Ventura, R; Zuccaro, P1
Kłys, M; Rojek, S; Rzepecka-Woźniak, E; Woźniak, K1
Bach, S; Ben Hamida, S; Cassel, JC; de Vasconcelos, AP; Jones, BC; Kelche, C; Lazarus, C; Plute, E; Tracqui, A1
Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Dirnagl, U; Fernandes, E; Ferreira, LM; Lobo, AM; Macedo, C; Meisel, A; Remião, F1
Cody, JT; Phelix, CF; Valtier, S1
Kamata, H; Katagi, M; Nemoto, N; Sakuma, T; Shima, N; Tsuchihashi, H1
Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA2
Eddington, ND; Upreti, VV1
Carter, JF; de Korompay, A; Hill, JC; NicDaeid, N; Sleeman, R1
Andersson, M; Beck, O; Gustavsson, E; Stephanson, N1
Huestis, MA; Kolbrich, EA; Lowe, RH1
Inoue, H; Iwata, YT; Kanamori, T; Kuwayama, K; Miyaguchi, H; Tsujikawa, K; Yoshida, T1
Jones, AW1
Ishii, H; Nakagawa, Y; Ogata, A; Suzuki, T; Tayama, S1
Cheong, JC; In, MK; Kim, JY; Kim, MK; Lee, JI1
Aasim, WR; Gan, SH; Tan, SC1
Beck, O; Bruhn, JG; El-Seedi, HR; Shulgin, AT; Stephanson, N1
Sun, J; Wang, C; Xu, X; You, T1
Bafile, E; Compagnone, D; Curini, R; D'Ascenzo, G; Romolo, FS; Sergi, M1
Meyer, JS; Piper, BJ; Vancollie, VE1
Cassel, JC; de Vasconcelos, AP; Hamida, SB; Jones, BC; Kelche, C; Lazarus, C; Szwarc, E; Tracqui, A1
Cheong, JC; In, MK; Jin, C; Kim, JY; Ko, BJ; Lee, SK; Yoo, HH1
Huestis, MA; Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA1
Choodum, A; Kanatharana, P; Smith, NW; Thavarungkul, P1
Black, DL; Caplan, YH; Cawthon, B; Cone, EJ; Moser, F; Robert, T1
Huestis, MA; Kolbrich, EA; Maurer, HH; McCann, UD; Mueller, M; Peters, FT; Ricaurte, GA1
Maurer, HH; Meyer, MR1
Hashimoto, H; Inoue, H; Iwata, YT; Kanamori, T; Kuwayama, K; Miyaguchi, H; Tachi, N; Tsujikawa, K; Uetake, N; Watanabe, S1
Maurer, HH; Meyer, MR; Peters, FT1
Felim, A; Largeron, M; Maurer, HH; McCann, UD; Mueller, M; Neudörffer, A; Peters, FT; Ricaurte, GA; Yuan, J1
Boy, RG; Henseler, J; Mattern, R; Ramaekers, JG; Skopp, G1
Debray, M; Declèves, X; Fonsart, J; Hirt, D; Menet, MC; Noble, F; Scherrmann, JM1
Cadet, JL; Huestis, MA; Ladenheim, B; Scheidweiler, KB1
Abraham, TT; Barnes, AJ; Goodwin, RS; Gorelick, DA; Huestis, MA; Kolbrich Spargo, EA; Lowe, RH; Milman, G; Pirnay, SO1
In, MK; Kim, JY; Lee, JI; Shin, SH1
Bastos, ML; Branco, P; Carmo, H; Carvalho, F; da Silva, DG; de Pinho, PG; Ferreira, L; Pontes, H; Remião, F1
Kaizaki, A; Numazawa, S; Tanaka, S; Tsujikawa, K; Yoshida, T1
Bastos, Mde L; Capela, JP; Carvalho, F; Dirnagl, U; Fernandes, E; Meisel, A; Ruscher, K; Wieloch, T1
Blacik, LJ; Kazarian, CM; Ntamack, AG; Romberg, RW; Snyder, JJ; Welsh, ER1
Inoue, H; Miyaguchi, H1
Inoue, H; Iwata, YT; Kanamori, T; Kuwayama, K; Mikuma, T; Miyaguchi, H; Tsujikawa, K1
Chen, BH; Chen, PH; Lee, HH; Lee, JF; Lin, SY1
Brenneisen, R; Grouzmann, E; Hoener, MC; Huwyler, J; Hysek, CM; Ineichen, M; Liechti, ME; Simmler, LD1
Hondebrink, L; Meulenbelt, J; van den Berg, M; van Kleef, RG; Westerink, RH1
Dickson, AJ; Holler, JM; Lyons, TP; Vorce, SP1
Hondebrink, L; Meijer, M; Meulenbelt, J; Rietjens, SJ; Westerink, RH1
Brugger, R; Bruggisser, M; Donzelli, M; Grouzmann, E; Hoener, MC; Hysek, CM; Liechti, ME; Simmler, LD1
Aaron, C; Freeman, S; Hedge, M; Leonard, K; Warrick, BJ; Wilson, J1
Almeida, B; Barenys, M; Boix, N; Flick, B; Joglar, J; Klug, S; Llobet, JM1
Baker, DR; Kasprzyk-Hordern, B1
Galceran, MT; Huerta-Fontela, M; Pineda, O; Ventura, F1
Donzelli, M; Grouzmann, E; Hoener, MC; Huwyler, J; Hysek, CM; Krähenbühl, S; Liechti, ME; Nicola, VG; Simmler, LD; Vischer, N1
Hermans, E; Hondebrink, L; Meulenbelt, J; Tan, S; van Kleef, RG; Westerink, RH1
Carmo, H; Carvalho, F; da Silva, DD; Silva, E1
Baumann, MH; Concheiro, M; Huestis, MA; Marrone, GF; Rothman, RB; Scheidweiler, KB1
Barbosa, DJ; Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R1
Cholanians, AB; Herndon, JM; Lau, SS; Monks, TJ1
Baumann, MH; Blough, BE; Goldberg, SR; Schindler, CW; Tella, SR; Thorndike, EB1
Baumgartner, MR; Hysek, CM; Kraemer, T; Liechti, ME; Madry, MM; Steuer, AE1
Covaci, A; Kinyua, J; Mardal, M; Meyer, MR; Miserez, B; Ramin, P; Van Nuijs, AL1
Bagnall, J; Evans, SE; Kasprzyk-Hordern, B1
Liechti, ME; Meyer Zu Schwabedissen, HE; Prestin, K; Schmid, Y; Vizeli, P1
Benzenhöfer, U; Passie, T1
Chao, YY; Chen, BH; Lee, CW; Lee, HH; Shen, JH; Shiea, J1
Krotulski, AJ; Logan, BK; Mohr, ALA; Papsun, DM1
Edwards, QA; Garner-O'Neale, LD; Kulikov, SM; Metcalfe, CD; Sultana, T; Yargeau, V1
Blanes, L; Bordin, DM; de Campos, EG; De Martinis, BS; Doble, P; Ishikawa, AA1
Burgueño, MJ; Castro, MÁ; Mateos-Campos, R; Sánchez, S1
Cui, J; Liu, W; Shen, B; Shen, M; Wang, X; Xiang, P; Zhang, S; Zhuo, Y1
Almeida, D; Castro, AL; Franco, JM; Sousa, L; Tarelho, S; Teixeira, HM1
Heifets, BD; Malenka, RC1
Bade, R; Gerber, C; Nguyen, L; Pandopulos, AJ; White, JM1
Carasek, E; de Oliveira, TF; Eller, S; Merib, J; Oenning, AL; Scheid, C1
Hudson, M; McDonnell, JM; Pollard, C; Royall, PG; Wolff, K1
Lee, WM; Li, CK; Wong, GF1
Ducret, P; Hoener, MC; Kolaczynska, KE; Liechti, ME; Luethi, D; Trachsel, D1
Coulter, C; Garnier, M; Moore, C1
Doucette, W; Wight, J1
Cruz, SL; Paz-Ramos, MI; Violante-Soria, V1
Beradinelli, D; Berretta, P; Busardò, FP; Chankvetadze, B; Di Giorgi, A; Farkas, T; Farre, M; Lo Faro, AF; Papaseit, E; Poyatos, L; Sprega, G; Takaishvili, N; Tini, A1
Kostick, KM; Schensul, JJ1

Reviews

35 review(s) available for n-methyl-3,4-methylenedioxyamphetamine and 3,4-methylenedioxyamphetamine

ArticleYear
Neurotoxic amphetamine analogues: effects in monkeys and implications for humans.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Central Nervous System; Designer Drugs; Haplorhini; Humans; Hydroxyindoleacetic Acid; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxins; Rats; Species Specificity

1992
[MDMA ("ecstasy"): a currently used drug in Spain].
    Revista clinica espanola, 1991, Volume: 188, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Chemical Phenomena; Chemistry; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Spain; Substance-Related Disorders

1991
Biogenic amines as biomarkers for neurotoxicity.
    Biomedical and environmental sciences : BES, 1991, Volume: 4, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Amines; Biomarkers; Female; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Reserpine

1991
["Ecstasy" and "ice": the return of the amphetamines].
    Harefuah, 1991, Jun-16, Volume: 120, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Substance-Related Disorders

1991
Ecstasy: towards an understanding of the biochemical basis of the actions of MDMA.
    Essays in biochemistry, 1991, Volume: 26

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; Humans; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Receptors, Neurotransmitter; Serotonin

1991
Neurochemistry and neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
    Journal of neurochemistry, 1990, Volume: 54, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Designer Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Cell Surface; Serotonin

1990
MDMA: historical perspectives.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1990
Neurotoxicity of MDMA and related compounds: anatomic studies.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Structure-Activity Relationship

1990
Neurotoxicity of MDMA: neurochemical effects.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Amines; Brain; Designer Drugs; Hydroxydopamines; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Oxidopamine; Serotonin

1990
Neurotoxic effect of MDMA on brain serotonin neurons: evidence from neurochemical and radioligand binding studies.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; Dopamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxins; Serotonin; Species Specificity

1990
Structure-activity relationships of MDMA-like substances.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Structure-Activity Relationship

1989
Acute and long-term neurochemical effects of methylenedioxymethamphetamine in the rat.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Time Factors

1989
Effects of MDMA and MDA on brain serotonin neurons: evidence from neurochemical and autoradiographic studies.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Autoradiography; Brain Chemistry; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Serotonin

1989
Characterization of brain interactions with methylenedioxyamphetamine and methylenedioxymethamphetamine.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Brain Chemistry; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1989
Studies of MDMA-induced neurotoxicity in nonhuman primates: a basis for evaluating long-term effects in humans.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Primates

1989
Toxicity of MDA (3,4-methylenedioxyamphetamine) considered for relevance to hazards of MDMA (Ecstasy) abuse.
    Alcohol and drug research, 1987, Volume: 7, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Humans; Lethal Dose 50; N-Methyl-3,4-methylenedioxyamphetamine; Species Specificity; Substance-Related Disorders

1987
Serotonergic mechanisms of hallucinogenic drug effects.
    Monographs in neural sciences, 1987, Volume: 13

    Topics: 3,4-Methylenedioxyamphetamine; Action Potentials; Animals; Brain; Hallucinogens; Lysergic Acid Diethylamide; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Serotonin

1987
Biological evaluation of compounds for their physical dependence potential and abuse liability. X. Drug testing programs of the Committee on Problems of Drug Dependence, Inc. (1986).
    NIDA research monograph, 1987, Volume: 76

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Appetite Depressants; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Meptazinol; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotics; Substance-Related Disorders

1987
Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place?
    Anaesthesia, 1993, Volume: 48, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Blood Coagulation Disorders; Dancing; Dantrolene; Designer Drugs; Female; Fever; Heat Exhaustion; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Renal Insufficiency; Rhabdomyolysis; Substance-Related Disorders

1993
Pharmacokinetic approaches to the study of drug action and toxicity.
    NIDA research monograph, 1993, Volume: 136

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1993
Contribution of serotonin neurotoxins to understanding psychiatric disorders: the role of 5-HT2 receptors in schizophrenia and antipsychotic activity.
    International clinical psychopharmacology, 1993, Volume: 8 Suppl 2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Dopamine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Serotonin; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists

1993
XTC-induced hepatitis.
    The Netherlands journal of medicine, 1994, Volume: 44, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Biopsy; Chemical and Drug Induced Liver Injury; Designer Drugs; Female; Humans; Jaundice; N-Methyl-3,4-methylenedioxyamphetamine

1994
3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans.
    Addiction (Abingdon, England), 1994, Volume: 89, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Brain; Designer Drugs; Dopamine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin

1994
[Ecstasy--effects and toxicity. Distinct risks but uncertain long-term hazards].
    Lakartidningen, 1993, Aug-11, Volume: 90, Issue:32-33

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Humans; Immunohistochemistry; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Risk Factors; Time Factors

1993
Caveats regarding the use of the laboratory rat as a model for acute toxicological studies: modulation of the toxic response via physiological and behavioral mechanisms.
    Toxicology, 1993, Jul-11, Volume: 81, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Animals, Laboratory; Behavior, Animal; Body Temperature; Body Temperature Regulation; Chlorphenamidine; Dose-Response Relationship, Drug; Heart Rate; N-Methyl-3,4-methylenedioxyamphetamine; Nickel; Ozone; Rats; Telemetry

1993
[Entactogenic drugs "ecstasy" (MDMA), "eve" (MDE) and other ring-substituted methamphetamine derivatives. A new class of substances among illegal designer drugs?].
    Der Nervenarzt, 1996, Volume: 67, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders

1996
Distribution of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) stereoisomers in a fatal poisoning.
    Forensic science international, 1996, Dec-02, Volume: 83, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cocaine; Fatal Outcome; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Stereoisomerism; Tissue Distribution

1996
Chemistry and pharmacology of hallucinogens, entactogens and stimulants.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Central Nervous System Stimulants; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methylenedioxyamphetamine; Structure-Activity Relationship

1998
[Poisoning with amphetamines and designer drugs].
    Der Internist, 1999, Volume: 40, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Drug Overdose; Humans; Illicit Drugs; Internal Medicine; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin Syndrome; Substance-Related Disorders

1999
Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Animals; Behavior, Animal; Brain; Deoxyepinephrine; Glutathione; Hallucinogens; Humans; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Rats; Serotonin Agents

2001
Altered states: the clinical effects of Ecstasy.
    Pharmacology & therapeutics, 2003, Volume: 98, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Brain; Clinical Trials as Topic; Cognition Disorders; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

2003
The Neuropsychopharmacology and Toxicology of 3,4-methylenedioxy-N-ethyl-amphetamine (MDEA).
    CNS drug reviews, 2004,Summer, Volume: 10, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Drug Administration Schedule; Drug Interactions; Europe; Hallucinogens; Humans; Illicit Drugs; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Neurotoxins; North America

2004
The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity.
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Blood-Brain Barrier; Catechols; Hallucinogens; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Reactive Oxygen Species; Sulfides

2004
MDA, MDMA, and other "mescaline-like" substances in the US military's search for a truth drug (1940s to 1960s).
    Drug testing and analysis, 2018, Volume: 10, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Drug Evaluation, Preclinical; Hallucinogens; Humans; Mescaline; Military Personnel; N-Methyl-3,4-methylenedioxyamphetamine; United States; World War II

2018
Amphetamine-type Stimulants: Novel Insights into their Actions and use Patterns.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2023, Volume: 75, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Central Nervous System Stimulants; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine

2023

Trials

12 trial(s) available for n-methyl-3,4-methylenedioxyamphetamine and 3,4-methylenedioxyamphetamine

ArticleYear
Second thoughts on 3,4-methylenedioxymethamphetamine (MDMA) neurotoxicity.
    Archives of general psychiatry, 1990, Volume: 47, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Clinical Trials as Topic; Designer Drugs; Humans; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Research Design; Substance-Related Disorders

1990
Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1994, Volume: 10, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Analysis of Variance; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Illicit Drugs; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Pain; Pain Measurement; Personality Tests; Prolactin; Serotonin

1994
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Deoxyepinephrine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Ion Exchange Resins; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards

1996
Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxymethamphetamine in humans.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Area Under Curve; Body Temperature; Cardiovascular System; Cross-Over Studies; Double-Blind Method; Hallucinogens; Hemodynamics; Human Growth Hormone; Humans; Hydrocortisone; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurosecretory Systems; Prolactin; Pupil

1999
Non-linear pharmacokinetics of MDMA ('ecstasy') in humans.
    British journal of clinical pharmacology, 2000, Volume: 49, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Area Under Curve; Blood Pressure; Cross-Over Studies; Deoxyepinephrine; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Hallucinogens; Humans; Hydrogen-Ion Concentration; Male; Metabolic Clearance Rate; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pilot Projects; Time Factors

2000
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.
    Journal of analytical toxicology, 2002, Volume: 26, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Deoxyepinephrine; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection

2002
Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid.
    Forensic science international, 2005, Oct-04, Volume: 153, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; ROC Curve; Saliva; Sensitivity and Specificity; Substance Abuse Detection

2005
The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA ("ecstasy") in humans.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Hallucinogens; Heart Rate; Humans; Male; Morpholines; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Reboxetine; Young Adult

2011
Effects of the α₂-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic alpha-2 Receptor Agonists; Adult; Affect; Blood Pressure; Body Temperature; Brain; Clonidine; Consciousness; Cross-Over Studies; Double-Blind Method; Drug Interactions; Emotions; Epinephrine; Female; Heart Rate; Humans; Male; Mental Processes; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Young Adult

2012
Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Biological Transport; Duloxetine Hydrochloride; Female; Humans; Laboratories; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Placebo Effect; Receptors, Adrenergic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thiophenes

2012
Evaluation of drug incorporation into hair segments and nails by enantiomeric analysis following controlled single MDMA intakes.
    Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Hair; Humans; Illicit Drugs; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Nails; Stereoisomerism; Substance Abuse Detection

2016
Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Cross-Sectional Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Double-Blind Method; Female; Genotype; Hallucinogens; Healthy Volunteers; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pharmacogenetics; Polymorphism, Genetic; Time Factors; Young Adult

2017

Other Studies

484 other study(ies) available for n-methyl-3,4-methylenedioxyamphetamine and 3,4-methylenedioxyamphetamine

ArticleYear
Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: representatives of a novel therapeutic class.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: Adult; Animals; Butylamines; Dioxoles; Discrimination Learning; Female; Generalization, Stimulus; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Psychotropic Drugs; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1986
Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Topics: Amphetamines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Phenethylamines; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Sulfur

2009
Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.
    Bioorganic & medicinal chemistry, 2010, Jun-01, Volume: 18, Issue:11

    Topics: Amphetamines; Cell Line; Cell Line, Tumor; Cells, Cultured; Humans; Methamphetamine; Neurons; Phenethylamines; Sulfur

2010
Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Alkenes; Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Molecular Structure; Nitro Compounds; Serotonin; Serotonin Plasma Membrane Transport Proteins

2011
An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.
    Bioorganic & medicinal chemistry letters, 2013, Jun-01, Volume: 23, Issue:11

    Topics: Allyl Compounds; HEK293 Cells; Humans; Indoles; Magnetic Resonance Spectroscopy; Molecular Conformation; Propylamines; Protein Binding; Psychotropic Drugs; Receptors, Serotonin; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Tryptamines

2013
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine.
    European journal of pharmacology, 1992, Sep-01, Volume: 228, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Quipazine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

1992
Possible interaction between an MAOI and "ecstasy".
    The American journal of psychiatry, 1992, Volume: 149, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Coma; Delirium; Designer Drugs; Drug Interactions; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Phenelzine; Serotonin; Substance-Related Disorders

1992
Flashbacks following MDMA.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Hallucinations; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Paranoid Disorders; Psychoses, Substance-Induced; Substance-Related Disorders

1992
Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA).
    Brain research bulletin, 1992, Volume: 28, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Immunoenzyme Techniques; Male; Microinjections; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin

1992
Hyperpyrexia and rhabdomyolysis after MDMA ("ecstasy") abuse.
    Lancet (London, England), 1992, Mar-14, Volume: 339, Issue:8794

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Fever; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rhabdomyolysis

1992
The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-01, Volume: 89, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biological Transport; Blood Platelets; Cattle; Cell Membrane; Cell-Free System; Chromaffin Granules; Designer Drugs; Humans; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Potassium; Serotonin

1992
Another death from Ecstacy.
    Journal of the Royal Society of Medicine, 1992, Volume: 85, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Death, Sudden; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Ecstasy--a dangerous drug.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1992, Apr-18, Volume: 81, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amitriptyline; Brain Ischemia; Depressive Disorder; Designer Drugs; Female; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Tranylcypromine

1992
Effects of 3,4-dihydroxymethamphetamine and 2,4,5-trihydroxymethamphetamine, two metabolites of 3,4-methylenedioxymethamphetamine, on central serotonergic and dopaminergic systems.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Injections, Intraventricular; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase

1992
Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat.
    European journal of pharmacology, 1992, Apr-07, Volume: 214, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Fluoxetine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains

1992
Phenomenology and sequelae of 3,4-methylenedioxymethamphetamine use.
    The Journal of nervous and mental disease, 1992, Volume: 180, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Combined Modality Therapy; Designer Drugs; Emotions; Female; Humans; Interpersonal Relations; Male; Mental Disorders; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Perception; Psychotherapy; Research Design; Substance-Related Disorders

1992
The MDMA-neurotoxicity controversy: implications for clinical research with novel psychoactive drugs.
    The Journal of nervous and mental disease, 1992, Volume: 180, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Combined Modality Therapy; Designer Drugs; Humans; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Nervous System Diseases; Psychotherapy; Research Design; Serotonin; Substance-Related Disorders; Synaptic Transmission

1992
Acute renal failure after ecstasy.
    BMJ (Clinical research ed.), 1992, Jul-04, Volume: 305, Issue:6844

    Topics: 3,4-Methylenedioxyamphetamine; Acute Kidney Injury; Adult; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Ecstasy and the dance of death.
    BMJ (Clinical research ed.), 1992, Jul-04, Volume: 305, Issue:6844

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders; Time Factors

1992
Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")
    Lancet (London, England), 1992, Aug-15, Volume: 340, Issue:8816

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Female; Humans; Infant; Male; Morbidity; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Recreational MDMA use in Sydney: a profile of 'Ecstacy' users and their experiences with the drug.
    British journal of addiction, 1992, Volume: 87, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Arousal; Australia; Designer Drugs; Euphoria; Female; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Pilot Projects; Substance-Related Disorders

1992
An overdose of ecstasy. A role for dantrolene.
    Anaesthesia, 1992, Volume: 47, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Dantrolene; Humans; Intensive Care Units; Intermittent Positive-Pressure Ventilation; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Complications of "ecstasy" misuse.
    Lancet (London, England), 1992, Sep-19, Volume: 340, Issue:8821

    Topics: 3,4-Methylenedioxyamphetamine; Anesthesia; Emergencies; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Complications of "ecstasy" misuse.
    Lancet (London, England), 1992, Sep-19, Volume: 340, Issue:8821

    Topics: 3,4-Methylenedioxyamphetamine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Complications of "ecstasy" misuse.
    Lancet (London, England), 1992, Sep-19, Volume: 340, Issue:8821

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Isomerism; Male; Mathematics; Models, Neurological; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1992
MDMA (Ecstasy) precipitation of panic disorder.
    Biological psychiatry, 1992, Jul-01, Volume: 32, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Agoraphobia; Alcohol Drinking; Amitriptyline; Arousal; Fluvoxamine; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Panic Disorder; Recurrence; Substance Withdrawal Syndrome; Tranylcypromine

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designer Drugs; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Chest Pain; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Cerebrovascular Disorders; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1992
Misuse of ecstasy.
    BMJ (Clinical research ed.), 1992, Aug-01, Volume: 305, Issue:6848

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Seizures; Substance-Related Disorders

1992
Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine.
    Brain research, 1992, May-29, Volume: 581, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Analysis of Variance; Animals; Aspartic Acid; Corpus Striatum; Designer Drugs; Dialysis; Dopamine; Glutamates; Kinetics; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Rats; Rats, Wistar; Reference Values; Taurine; Time Factors

1992
The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine.
    European journal of pharmacology, 1992, May-14, Volume: 215, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cocaine; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes

1992
Drugs, music, and ideology: a social pharmacological interpretation of the Acid House Movement.
    The International journal of the addictions, 1992, Volume: 27, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Humans; Leisure Activities; Lysergic Acid Diethylamide; Mass Media; Music; N-Methyl-3,4-methylenedioxyamphetamine; Social Behavior; Substance-Related Disorders; United Kingdom

1992
Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Brain; Drug Interactions; Drug Tolerance; Indoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

1992
Attenuation of alcohol consumption by MDMA (ecstasy) in two strains of alcohol-preferring rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Alcohol Drinking; Animals; Body Temperature; Drinking Behavior; Eating; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Species Specificity

1992
Chronic 3,4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function?
    The American journal of drug and alcohol abuse, 1992, Volume: 18, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cognition Disorders; Depressive Disorder; Female; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Serotonin; Substance-Related Disorders; Wechsler Scales

1992
Accidental ingestion of 'Ecstasy' (3,4-methylenedioxymethylamphetamine).
    Archives of disease in childhood, 1992, Volume: 67, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Chlormethiazole; Heart Rate; Humans; Infant; Male; N-Methyl-3,4-methylenedioxyamphetamine; Poisoning; Seizures

1992
Serotonin 5-HT1-like receptors mediate hyperactivity in rats induced by 3,4-methylenedioxymethamphetamine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists

1992
Ecstasy and the dance of death.
    BMJ (Clinical research ed.), 1992, Sep-26, Volume: 305, Issue:6856

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Humans; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine

1992
Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine but not by 2-hydroxy-4,5-methylenedioxymethamphetamine or 2-hydroxy-4,5-methylenedioxyamphetamine.
    European journal of pharmacology, 1992, Oct-20, Volume: 221, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1992
Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors.
    Neuropharmacology, 1992, Volume: 31, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain; Brain Chemistry; Down-Regulation; Half-Life; Iodine Radioisotopes; Kinetics; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin

1992
Investigation of MDMA-related agents in rats trained to discriminate MDMA from saline.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Discrimination, Psychological; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

1992
MDMA ("ecstasy") and panic disorder: induction by a single dose.
    Biological psychiatry, 1992, Nov-15, Volume: 32, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Alprazolam; Anxiety Disorders; Arousal; Designer Drugs; Dose-Response Relationship, Drug; Humans; Imipramine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Panic; Panic Disorder; Recurrence

1992
Ecstasy and dantrolene.
    BMJ (Clinical research ed.), 1992, Nov-14, Volume: 305, Issue:6863

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1992
The N-methyl-D-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine, 3,4-methylenedioxymethamphetamine and p-chloroamphetamine.
    Brain research, 1992, Nov-06, Volume: 595, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dizocilpine Maleate; Hippocampus; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; N-Methylaspartate; p-Chloroamphetamine; Rats; Serotonin

1992
Further studies on N-methyl-1(3,4-methylenedioxyphenyl)-2-aminopropane as a discriminative stimulus: antagonism by 5-hydroxytryptamine3 antagonists.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Discrimination, Psychological; Dopamine Antagonists; Generalization, Stimulus; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists

1992
5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine.
    European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Dialysis; Dopamine; Fluorobenzenes; Haloperidol; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Antagonists

1992
Comparative investigation of disposition of 3,4-(methylenedioxy)methamphetamine (MDMA) in the rat and the mouse by a capillary gas chromatography-mass spectrometry assay based on perfluorotributylamine-enhanced ammonia positive ion chemical ionization.
    Journal of pharmaceutical and biomedical analysis, 1992, Volume: 10, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Ammonia; Animals; Dopamine; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; Mice; Mice, Inbred Strains; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Species Specificity

1992
[Studies on the identification of psychotropic substances (VII). Preparation and various analytical data of standard references of some hallucinogens, 3,4-methylenedioxyamphetamine (MDA), 3,4- methylenedioxymethamphetamine (MDMA) and 5-methoxy-3,4- methyl
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1990, Issue:108

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Spectrophotometry

1990
Effect of flunarizine and nimodipine on the decrease in tryptophan hydroxylase activity induced by methamphetamine and 3,4-methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Diltiazem; Drug Interactions; Enzyme Induction; Flunarizine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Serotonin; Tryptophan Hydroxylase

1992
Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dopamine; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Paroxetine; Piperidines; Saimiri; Serotonin; Serotonin Antagonists

1992
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1992
Evaluation of the neurotoxicity of N-methyl-1-(4-methoxyphenyl)-2-aminopropane (para-methoxymethamphetamine, PMMA).
    Brain research, 1992, Sep-04, Volume: 589, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Hallucinogens; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Rats, Sprague-Dawley; Serotonin; Structure-Activity Relationship

1992
Effects of benzylpiperazine derivatives on the neurotoxicity of 3,4-methylenedioxymethamphetamine in rat brain.
    Brain research, 1992, Sep-11, Volume: 590, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Wistar; Serotonin

1992
Chronic paranoid psychosis after misuse of MDMA ("ecstasy")
    BMJ (Clinical research ed.), 1991, Mar-23, Volume: 302, Issue:6778

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paranoid Disorders; Substance-Related Disorders

1991
Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA).
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Brain; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Indans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship

1991
Chronic paranoid psychosis after misuse of MDMA.
    BMJ (Clinical research ed.), 1991, May-11, Volume: 302, Issue:6785

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paranoid Disorders; Psychoses, Substance-Induced; Substance-Related Disorders

1991
Methylenedioxymethamphetamine induces spontaneous tail-flicks in the rat via 5-HT1A receptors.
    European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reflex; Serotonin; Serotonin Antagonists; Tail

1991
MDMA: further evidence that its action in the medial prefrontal cortex is mediated by the serotonergic system.
    Brain research, 1991, Jan-25, Volume: 539, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cerebral Cortex; Electrophysiology; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Stereoisomerism; Stereotaxic Techniques

1991
The action of (+/-)-MDMA on medial prefrontal cortical neurons is mediated through the serotonergic system.
    Brain research, 1991, Mar-08, Volume: 543, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 5-Hydroxytryptophan; alpha-Methyltyrosine; Analysis of Variance; Animals; Cerebral Cortex; Designer Drugs; Dopamine; Electrophysiology; Fenclonine; Levodopa; Male; Methyltyrosines; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Inbred Strains; Reference Values; Serotonin

1991
Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autonomic Nervous System; Body Temperature; Body Temperature Regulation; Electrocardiography; Heart Rate; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Regional Blood Flow; Tail; Telemetry

1991
Assessment of the role of alpha-methylepinine in the neurotoxicity of MDMA.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Amines; Brain Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Electrochemistry; Injections, Intraventricular; Male; Mice; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Species Specificity

1991
Methods for the analysis of 1-(3,4-methylenedioxyphenyl)-2-butanamine and N-methyl-1-(3,4-methylenedioxyphenyl)-2-propanamine (MDMA).
    Journal of chromatographic science, 1991, Volume: 29, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, Liquid; Forensic Medicine; N-Methyl-3,4-methylenedioxyamphetamine

1991
Ecstasy, 3-4 methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia.
    Journal of the Royal Society of Medicine, 1991, Volume: 84, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Designer Drugs; Disseminated Intravascular Coagulation; Female; Fever; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1991
In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements.
    Journal of neuroscience methods, 1991, Volume: 36, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Electrophysiology; In Vitro Techniques; Male; Microchemistry; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1991
Effect of MDMA neurotoxicity upon its conditioned place preference and discrimination.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Choice Behavior; Conditioning, Classical; Designer Drugs; Discrimination Learning; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Rats; Rats, Inbred Strains; Sodium Chloride

1991
High performance liquid chromatographic assays of the illicit designer drug "Ecstasy", a modified amphetamine, with applications to stability, partitioning and plasma protein binding.
    Acta pharmaceutica Nordica, 1991, Volume: 3, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Blood Proteins; Chromatography, High Pressure Liquid; Designer Drugs; Drug Stability; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1991
3,4-Methylenedioxymethamphetamine induces Fos-like proteins in rat basal ganglia: reversal with MK 801.
    European journal of pharmacology, 1991, Mar-25, Volume: 206, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Basal Ganglia; Caudate Nucleus; Corpus Striatum; Dizocilpine Maleate; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Olfactory Bulb; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Putamen; Rats

1991
Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations. Participation of different cytochrome P450 isozymes in the demethylenation reaction.
    Biochemical pharmacology, 1991, Aug-08, Volume: 42, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Gas Chromatography-Mass Spectrometry; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Phenobarbital; Rabbits

1991
Determination of the mechanism of demethylenation of (methylenedioxy)phenyl compounds by cytochrome P450 using deuterium isotope effects.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cytochrome P-450 Enzyme System; Deuterium; Hydroxides; Hydroxyl Radical; Isotopes; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rabbits; Substrate Specificity

1991
Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain; Dopamine; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Time Factors

1991
Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluoxetine; Ketanserin; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Serotonin

1991
Chronic atypical psychosis associated with MDMA ("ecstasy") abuse.
    Lancet (London, England), 1991, Nov-23, Volume: 338, Issue:8778

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Chronic Disease; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Substance-Related Disorders

1991
MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Conditioning, Operant; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropanes

1991
5-HT, MDMA (ecstasy), and nimodipine effects on 45Ca-uptake into rat brain synaptosomes.
    Annals of the New York Academy of Sciences, 1991, Volume: 635

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Calcium; Calcium Radioisotopes; N-Methyl-3,4-methylenedioxyamphetamine; Nimodipine; Rats; Serotonin; Synaptosomes

1991
Psychiatric illness associated with "ecstasy".
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Depressive Disorder; Humans; Infant; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced

1991
Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy").
    Psychopharmacology, 1991, Volume: 105, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Deoxyglucose; Glucose; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1991
Possible serotonergic and dopaminergic mediation of the N-ethyl-3,4-methylenedioxyamphetamine discriminative stimulus.
    European journal of pharmacology, 1991, Sep-24, Volume: 202, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Discrimination Learning; Fenclonine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1991
'Ecstasy' psychosis and flashbacks.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Delusions; Euphoria; Female; Humans; Male; Mental Recall; N-Methyl-3,4-methylenedioxyamphetamine; Neurocognitive Disorders

1991
Lasting neuropsychiatric sequelae of (+-)methylenedioxymethamphetamine ('ecstasy') in recreational users.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Anxiety Disorders; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Psychometrics; Psychoses, Substance-Induced; Substance-Related Disorders

1991
[3H]monoamine releasing and uptake inhibition properties of 3,4-methylenedioxymethamphetamine and p-chloroamphetamine analogues.
    European journal of pharmacology, 1991, Jul-23, Volume: 200, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Regression Analysis; Reserpine; Serotonin; Synaptosomes

1991
Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Fluoxetine; Microchemistry; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Secretory Rate; Serotonin; Tryptophan

1991
L-DOPA potentiation of the serotonergic deficits due to a single administration of 3,4-methylenedioxymethamphetamine, p-chloroamphetamine or methamphetamine to rats.
    European journal of pharmacology, 1991, Oct-02, Volume: 203, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Synergism; Fenfluramine; Hippocampus; Levodopa; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Nervous System Diseases; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin

1991
In vivo formation of aromatic hydroxylated metabolites of 3,4-(methylenedioxy)methamphetamine in the rat: identification by ion trap tandem mass spectrometric (MS/MS and MS/MS/MS) techniques.
    Biological mass spectrometry, 1991, Volume: 20, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Animals; Brain Chemistry; Injections, Subcutaneous; Liver; Male; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1991
MDMA produces a conditioned place preference and elicits ejaculation in male rats: a modulatory role for the endogenous opioids.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Conditioning, Operant; Defecation; Ejaculation; Endorphins; Male; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropanes; Urination

1991
Effect of 3,4-methylenedioxymethamphetamine on 3,4-dihydroxyphenylalanine accumulation in the striatum and nucleus accumbens.
    Journal of neurochemistry, 1990, Volume: 54, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Serotonin; Serotonin Antagonists

1990
Enantiomeric differences in the effects of 3,4-methylenedioxymethamphetamine on extracellular monoamines and metabolites in the striatum of freely-moving rats: an in vivo microdialysis study.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Electrochemistry; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1990
Reduction of in vivo binding of [3H]paroxetine in mouse brain by 3,4-methylenedioxymethamphetamine.
    Neuropharmacology, 1990, Volume: 29, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydroxyindoleacetic Acid; Injections, Intravenous; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Serotonin; Serotonin Antagonists

1990
Risk assessment for neurotoxic effects.
    Neurotoxicology, 1990,Summer, Volume: 11, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Axons; Designer Drugs; Female; Hippocampus; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Rats, Inbred Strains; Risk; Serotonin

1990
Aminergic metabolites in cerebrospinal fluid of humans previously exposed to MDMA: preliminary observations.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Biogenic Amines; Designer Drugs; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Reference Values; Substance-Related Disorders

1990
Effect of 3,4-methylenedioxymethamphetamine on [3H]paroxetine binding in the frontal cortex and blood platelets of rats.
    Biochemical pharmacology, 1991, Jan-01, Volume: 41, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Blood Platelets; Frontal Lobe; Hydroxyindoleacetic Acid; Ketanserin; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Time Factors; Tritium

1991
Reduction of [3H]6-nitroquipazine-labelled 5-hydroxytryptamine uptake sites in rat brain by 3,4-methylenedioxymethamphetamine.
    Fundamental & clinical pharmacology, 1990, Volume: 4, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Binding Sites; Brain; Drug Interactions; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Quipazine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tritium

1990
Lack of neurotoxicity after intra-raphe micro-injections of MDMA ("ecstasy").
    NIDA research monograph, 1990, Volume: 105

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Immunohistochemistry; Indoles; Male; Microinjections; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin

1990
Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Electrochemistry; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin

1991
The neurochemical and stimulatory effects of putative metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in rats.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Central Nervous System Stimulants; Cerebral Cortex; Deoxyepinephrine; Dopamine; Epinephrine; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nordefrin; Rats; Rats, Inbred Strains; Serotonin

1991
The effects of repeated administration of MDMA on the expression of sexual behavior in the male rat.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Corpus Striatum; Ejaculation; Hippocampus; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin; Sexual Behavior, Animal

1991
A pharmacokinetic analysis of 3,4-methylenedioxymethamphetamine effects on monoamine concentrations in brain dialysates.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Biological Availability; Brain Chemistry; Corpus Striatum; Dialysis; Dopamine; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Isomerism; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin

1991
Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA) analogue.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Brain; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Indans; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin

1991
Intrasynaptosomal sequestration of [3H]amphetamine and [3H]methylenedioxyamphetamine: characterization suggests the presence of a factor responsible for maintaining sequestration.
    Journal of neurochemistry, 1990, Volume: 54, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Brain; Cell Fractionation; Designer Drugs; Digitonin; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Synaptosomes; Thermodynamics

1990
Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA).
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Catecholamines; Cerebral Cortex; Hippocampus; Indans; Lysergic Acid Diethylamide; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Psychotropic Drugs; Rats; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1990
Application of entropy measures derived from the ergodic theory of dynamical systems to rat locomotor behavior.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Dextroamphetamine; Male; Mathematics; Models, Neurological; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Reference Values

1990
MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2(+)-dependent toxicity linked to release.
    Brain research, 1990, Feb-26, Volume: 510, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cells, Cultured; Embryo, Mammalian; Fluoxetine; Ketanserin; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Serotonin

1990
Central action of psychomotor stimulants on glucose utilization in extrapyramidal motor areas of the rat brain.
    Brain research, 1990, Mar-26, Volume: 512, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cocaine; Designer Drugs; Glucose; Male; Movement; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Rats; Rats, Inbred F344

1990
Tolerance and cross-tolerance to 3,4-methylenedioxymethamphetamine (MDMA), methamphetamine and methylenedioxyamphetamine.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Tolerance; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1990
5-hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents.
    European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synaptosomes

1990
3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Electrophysiology; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Serotonin; Tryptophan

1990
Three-choice discrimination among (+)-amphetamine, fenfluramine and saline in pigeons.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Columbidae; Discrimination, Psychological; Female; Fenfluramine; Generalization, Stimulus; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Chloride

1990
Neurochemistry and neurotoxicity of substituted amphetamines.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Fenfluramine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin

1990
Serotonergic modulation of rat pup ultrasonic vocal development: studies with 3,4-methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Ultrasonics; Vocalization, Animal

1990
Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; Fluoxetine; Gait; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin

1990
Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyepinephrine; Glutathione; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1990
Reversal of the acute effects of 3,4-methylenedioxymethamphetamine by 5-HT uptake inhibitors.
    European journal of pharmacology, 1990, May-31, Volume: 181, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Fluoxetine; Indenes; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase

1990
Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine.
    European journal of pharmacology, 1990, May-31, Volume: 181, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Brain; Catecholamines; Hydroxydopamines; Indoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Oxidopamine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Substantia Nigra; Tryptophan Hydroxylase

1990
Neurochemical basis of neurotoxicity.
    Neurotoxicology, 1990,Summer, Volume: 11, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Designer Drugs; Dopamine; Glutamates; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Nervous System Diseases; Serotonin

1990
Identification of metabolites of 3,4-methylenedioxymethamphetamine in rats.
    Drug and alcohol dependence, 1990, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Gas Chromatography-Mass Spectrometry; Inactivation, Metabolic; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1990
Selective 5-hydroxytryptamine2 receptor antagonists protect against the neurotoxicity of methylenedioxymethamphetamine in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Brain; Cerebral Cortex; Dopamine; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase

1990
Structure-activity relationships of MDMA and related compounds: a new class of psychoactive drugs?
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Conditioning, Operant; Discrimination, Psychological; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1990
Receptor pharmacology of MDMA and related hallucinogens.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Designer Drugs; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Ketanserin; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin

1990
Effects of MDMA ('ecstasy') on firing rates of serotonergic, dopaminergic, and noradrenergic neurons in the rat.
    Brain research, 1990, Sep-03, Volume: 526, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Action Potentials; Animals; Designer Drugs; Dopamine; Electrodes, Implanted; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin

1990
(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hallucinogens; Indans; Learning; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1990
Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis.
    Life sciences, 1990, Volume: 47, Issue:26

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin

1990
Paroxetine as an in vivo indicator of 3,4-methylenedioxymethamphetamine neurotoxicity: a presynaptic serotonergic positron emission tomography ligand?
    Brain research, 1990, Sep-10, Volume: 527, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Ligands; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synapses; Tomography, Emission-Computed; Tritium

1990
Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Cerebral Cortex; Corpus Striatum; Haloperidol; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists

1990
Chloral hydrate anesthesia antagonizes the neurotoxicity of 3,4-methylenedioxymethamphetamine.
    European journal of pharmacology, 1990, Nov-27, Volume: 191, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Anesthesia; Animals; Cerebral Cortex; Chloral Hydrate; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Premedication; Rats; Rats, Inbred Strains; Serotonin

1990
Effects of methylenedioxymethamphetamine on the release of monoamines from rat brain slices.
    European journal of pharmacology, 1990, Nov-27, Volume: 191, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Female; Hippocampus; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin

1990
Diminished corticotropin and enhanced prolactin responses to 8-hydroxy-2(di-n-propylamino)tetralin in methylenedioxymethamphetamine pretreated rats.
    Neuropharmacology, 1990, Volume: 29, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Drug Interactions; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Rats; Rats, Inbred Strains; Reference Values; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Behavioral, biochemical and neurotoxicological actions of the alpha-ethyl homologue of p-chloroamphetamine.
    European journal of pharmacology, 1990, Nov-20, Volume: 191, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Biological Transport, Active; Brain; Discrimination Learning; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin

1990
Methylenedioxymethamphetamine's capacity to establish place preferences and modify intake of an alcoholic beverage.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Alcohol Drinking; Animals; Body Weight; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1990
Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue.
    European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Time Factors

1986
Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cerebral Cortex; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Time Factors

1987
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Brain Chemistry; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium

1987
Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats.
    Neuropharmacology, 1987, Volume: 26, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Corpus Striatum; Hippocampus; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Species Specificity; Time Factors; Tryptophan Hydroxylase

1987
The effects of amphetamine-like designer drugs on monoaminergic systems in rat brain.
    NIDA research monograph, 1987, Volume: 76

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase

1987
MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biological Transport, Active; Brain; Dose-Response Relationship, Drug; Guinea Pigs; Hydroxyindoleacetic Acid; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Regeneration; Neurons; Rats; Rats, Inbred Strains; Serotonin; Species Specificity

1988
(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates.
    JAMA, 1988, Jul-01, Volume: 260, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dose-Response Relationship, Drug; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Macaca fascicularis; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Fibers; Neurons; Raphe Nuclei; Saimiri; Serotonin

1988
Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA).
    Toxicology and applied pharmacology, 1988, Volume: 94, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Amphetamines; Animals; Brain; Brain Chemistry; Dopamine; Female; Hydroxyindoleacetic Acid; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Species Specificity

1988
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Axons; Catecholamines; Cell Survival; Diencephalon; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurotoxins; Rats; Rats, Inbred Strains; Serotonin; Staining and Labeling; Telencephalon

1988
5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates.
    Brain research, 1988, Dec-06, Volume: 474, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cebidae; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Serotonin

1988
Direct central effects of acute methylenedioxymethamphetamine on serotonergic neurons.
    European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cerebral Cortex; Hydroxyindoleacetic Acid; In Vitro Techniques; Infusions, Parenteral; Injections; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Tryptophan Hydroxylase; Tumor Cells, Cultured

1988
Glucocorticoids and 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity.
    European journal of pharmacology, 1989, Feb-28, Volume: 161, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adrenalectomy; Amphetamines; Animals; Cerebral Cortex; Corticosterone; Glucocorticoids; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase

1989
3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Norepinephrine; Serotonin

1989
Effects of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine isomers on central serotonergic, dopaminergic and nigral neurotensin systems of the rat.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotensin; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Substantia Nigra; Tryptophan Hydroxylase

1988
Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys.
    Brain research, 1989, May-29, Volume: 488, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Macaca; Macaca mulatta; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin

1989
Selective reduction of striatal type II glucocorticoid receptors in rats by 3,4-methylenedioxymethamphetamine (MDMA).
    European journal of pharmacology, 1989, Apr-12, Volume: 163, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Androstanols; Animals; Corpus Striatum; Corticosterone; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Serotonin

1989
Neurotoxic effects of the alpha-ethyl homologue of MDMA following subacute administration.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Brain Chemistry; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1989
Effects of amphetamine analogs on central nervous system neuropeptide systems.
    NIDA research monograph, 1989, Volume: 94

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Dynorphins; Extrapyramidal Tracts; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neuropeptides; Neurotensin; Rats; Rats, Inbred Strains; Substance P

1989
Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Preliminary observations.
    Archives of general psychiatry, 1989, Volume: 46, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Infusions, Intravenous; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Serotonin; Substance-Related Disorders; Tryptophan

1989
"Ecstasy" (MDMA)-induced panic.
    The American journal of psychiatry, 1989, Volume: 146, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Depressive Disorder; Fear; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Panic

1989
'Ecstasy': a human neurotoxin?
    Archives of general psychiatry, 1989, Volume: 46, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Nervous System Diseases; Substance-Related Disorders

1989
Blasted with ennui.
    BMJ (Clinical research ed.), 1989, Jan-21, Volume: 298, Issue:6667

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1989
In vitro reactivation of rat cortical tryptophan hydroxylase following in vivo inactivation by methylenedioxymethamphetamine.
    Journal of neurochemistry, 1989, Volume: 53, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Enzyme Activation; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors; Tryptophan Hydroxylase

1989
Hallucinogenic and stimulatory amphetamine derivatives: fingerprinting DOM, DOI, DOB, MDMA, and MBDB by spectral analysis of brain field potentials in the freely moving rat (Tele-Stereo-EEG).
    Psychopharmacology, 1989, Volume: 98, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Central Nervous System Stimulants; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electroencephalography; Evoked Potentials; Hallucinogens; Injections, Intraperitoneal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred F344; Telemetry

1989
Behavioral effects of (+-) 3,4-methylenedioxyamphetamine (MDA) and (+-) 3,4-methylenedioxymethamphetamine (MDMA) in the pigeon: interactions with noradrenergic and serotonergic systems.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Metergoline; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Reinforcement Schedule; Serotonin; Sympathetic Nervous System

1989
Stereochemistry of the metabolism of MDMA to MDA.
    Life sciences, 1989, Volume: 45, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biotransformation; Female; Gas Chromatography-Mass Spectrometry; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1989
Ecstasy abuse.
    The New Zealand medical journal, 1989, Aug-23, Volume: 102, Issue:874

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; New Zealand; Substance-Related Disorders

1989
Effect of MK-801 on the decrease in tryptophan hydroxylase induced by methamphetamine and its methylenedioxy analog.
    European journal of pharmacology, 1989, Jun-20, Volume: 165, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tryptophan Hydroxylase

1989
A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Desipramine; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Oxidopamine; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Septal Nuclei

1989
Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Designer Drugs; Dose-Response Relationship, Drug; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Time Factors

1989
MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin.
    European journal of pharmacology, 1989, Aug-29, Volume: 167, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Dialysis; Electrophysiology; Fluoxetine; In Vitro Techniques; Male; Mesencephalon; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Passive Cutaneous Anaphylaxis; Raphe Nuclei; Rats; Serotonin; Stereoisomerism; Time Factors

1989
Effects of methylenedioxymethamphetamine on local cerebral glucose utilization in the rat.
    Neuropharmacology, 1989, Volume: 28, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Autoradiography; Blood Pressure; Brain Chemistry; Brain Stem; Glucose; Heart Rate; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred F344; Stereotyped Behavior

1989
Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat.
    Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Corpus Striatum; Designer Drugs; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nervous System Diseases; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reserpine; Serotonin

1989
The effect of optical isomers of 3,4-methylenedioxymethamphetamine (MDMA) on stereotyped behavior in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism; Stereotyped Behavior; Time Factors

1989
Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled behavior of rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Conditioning, Psychological; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Serotonin; Time Factors

1989
The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) in rats.
    Neuroscience letters, 1989, Nov-06, Volume: 105, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Calcium; Dextrorphan; Male; Morphinans; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1989
MDMA produces stimulant-like conditioned locomotor activity.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1989
(+/-)-3,4-Methylenedioxymethamphetamine-induced changes in the basal activity and pharmacological responsiveness of nigrostriatal dopamine neurons.
    European journal of pharmacology, 1989, Oct-04, Volume: 169, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Apomorphine; Biogenic Amines; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Quinpirole; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra

1989
Inhibition of dopamine release by methylenedioxymethamphetamine is mediated by serotonin.
    European journal of pharmacology, 1989, Sep-13, Volume: 168, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin

1989
Effects of (+-)3,4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Haloperidol; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors

1989
Stimulus effects of N-monoethyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDE) and N-hydroxy-1-(3,4-methylenedioxyphenyl)-2-aminopropane (N-OH MDA) in rats trained to discriminate MDMA from saline.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1989
MDMA transiently alters biogenic amines and metabolites in mouse brain and heart.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Heart; Male; Mice; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Serotonin

1989
The antinociceptive effects of 3,4-methylenedioxymethamphetamine (MDMA) in the rat.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analgesics; Animals; Dose-Response Relationship, Drug; Male; Methysergide; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Pain; Rats; Rats, Inbred Strains; Receptors, Serotonin

1989
Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA.
    Neurotoxicology, 1989,Fall, Volume: 10, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biotransformation; Brain Chemistry; Cerebral Cortex; Dealkylation; Female; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Phenobarbital; Proadifen; Proteins; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1989
Behavioral and neurochemical effects of orally administered MDMA in the rodent and nonhuman primate.
    Neurotoxicology, 1989,Fall, Volume: 10, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; beta-Endorphin; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Female; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Reaction Time; Reflex, Startle; Sex Factors

1989
Psychostimulant properties of MDMA.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Arousal; Brain; Designer Drugs; Dose-Response Relationship, Drug; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Receptors, Dopamine; Receptors, Serotonin

1989
Comparison of the behavioral and neurochemical effects of 5,7-DHT, MDMA and D,L-fenfluramine.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Amphetamines; Animals; Arousal; Behavior, Animal; Brain; Designer Drugs; Dihydroxytryptamines; Fenfluramine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1989
Responses to i.v. L-tryptophan in MDMA users.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Receptors, Serotonin; Substance-Related Disorders; Tryptophan

1989
MK-801 attenuates the methamphetamine induced decreased in tryptophan hydroxylase activity.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Anticonvulsants; Brain; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Serotonin; Tryptophan Hydroxylase

1989
Depression to ecstasy. The Neuropharmacology of Serotonin sponsored by the New York Academy of Sciences, New York, NY, USA, July 10-13, 1989.
    The New biologist, 1989, Volume: 1, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Mapping; Depression; Humans; Mental Disorders; Migraine Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Neuronal Plasticity; Pain; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sex Factors; Sleep; Structure-Activity Relationship

1989
Information on "Ecstasy".
    The American journal of psychiatry, 1985, Volume: 142, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Drug and Narcotic Control; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Psychotherapy; United States

1985
A bit on the Wilde side: MDMA abuse.
    North Carolina medical journal, 1985, Volume: 46, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Drama; Famous Persons; Hallucinogens; Humans; Literature; Literature, Modern; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1985
Evidence for specific methylenedioxymethamphetamine (ecstasy) binding sites in the rat brain.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Binding Sites; Binding, Competitive; Brain; Dextroamphetamine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1985
3,4-Methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Male; Molecular Conformation; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship

1986
Discriminative profile of MDMA.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Apomorphine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Fenfluramine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Receptors, Dopamine; Receptors, Serotonin

1986
The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain.
    European journal of pharmacology, 1986, Aug-22, Volume: 128, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine 3-Monooxygenase

1986
Can drugs be used to enhance the psychotherapeutic process?
    American journal of psychotherapy, 1986, Volume: 40, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Awareness; Female; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Mental Disorders; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Psychotherapy; Self Disclosure

1986
Designer drug confusion: a focus on MDMA.
    Journal of drug education, 1986, Volume: 16, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Drug and Narcotic Control; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Terminology as Topic; United States

1986
Spectral and inhibitory interactions of (+/-)-3,4-methylenedioxyamphetamine (MDA) and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) with rat hepatic microsomes.
    Life sciences, 1986, Oct-20, Volume: 39, Issue:16

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Kinetics; Male; Methamphetamine; Methimazole; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; NADP; Oxidoreductases, N-Demethylating; Rats; Spectrophotometry

1986
The effects of (+/-)-methylenedioxymethamphetamine and (+/-)-methylenedioxyamphetamine in monkeys trained to discriminate (+)-amphetamine from saline.
    Drug and alcohol dependence, 1986, Volume: 18, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Avoidance Learning; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Food; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine

1986
Self-administration of methylenedioxymethamphetamine (MDMA) by rhesus monkeys.
    Drug and alcohol dependence, 1986, Volume: 18, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cocaine; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; Self Administration

1986
Discriminative stimulus properties of (+/-)-3,4-methylenedioxymethamphetamine and (+/-)-3,4-methylenedioxyamphetamine in pigeons.
    Drug and alcohol dependence, 1986, Volume: 18, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Columbidae; Discrimination Learning; Discrimination, Psychological; N-Methyl-3,4-methylenedioxyamphetamine

1986
Effects of the enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices.
    European journal of pharmacology, 1986, Dec-16, Volume: 132, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Caudate Nucleus; Dopamine; Hippocampus; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1986
'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA.
    JAMA, 1987, Mar-27, Volume: 257, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Accidents; Adolescent; Adult; Amphetamines; Arrhythmias, Cardiac; Asthma; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Heart Diseases; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1987
In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain.
    Biochemical pharmacology, 1987, Mar-01, Volume: 36, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Citalopram; Corpus Striatum; Dopamine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1987
Self-injection of d,1-3,4-methylenedioxymethamphetamine (MDMA) in the baboon.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cocaine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Papio; Self Administration

1987
A comparison of the neurotoxic potential of methylenedioxyamphetamine (MDA) and its N-methylated and N-ethylated derivatives.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1987
Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Somatosensory Cortex; Synaptosomes; Tissue Distribution

1987
Effects of phencyclidine, ketamine and MDMA on complex operant behavior in monkeys.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Erythrocebus patas; Ketamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Reinforcement, Psychology

1987
The effect of MDMA ("Ecstasy") and its optical isomers on schedule-controlled responding in mice.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; N-Methyl-3,4-methylenedioxyamphetamine; Reinforcement Schedule; Stereoisomerism; Structure-Activity Relationship

1987
A case of MAO inhibitor/MDMA interaction: agony after ecstasy.
    Journal of toxicology. Clinical toxicology, 1987, Volume: 25, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Drug Interactions; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Phenelzine

1987
Acute administration of methylenedioxymethamphetamine: comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs.
    European journal of pharmacology, 1987, Apr-07, Volume: 136, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Cerebral Cortex; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Synaptosomes

1987
Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Biological Transport; Corpus Striatum; Depression, Chemical; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dopamine; Hippocampus; Hypothalamus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Synaptosomes

1987
3,4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin

1987
Multiple severe complications from recreational ingestion of MDMA ('Ecstasy')
    JAMA, 1987, Aug-14, Volume: 258, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Female; Fever; Hallucinations; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1987
MDMA as a discriminative stimulus: isomeric comparisons.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Discrimination Learning; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism; Time Factors

1987
Effects of amphetamine analogs on neurotensin concentrations in rat brain.
    European journal of pharmacology, 1987, Jun-12, Volume: 138, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotensin; Rats; Rats, Inbred Strains

1987
(+/-)3,4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats.
    European journal of pharmacology, 1987, Jun-19, Volume: 138, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Cerebral Cortex; Dopamine; Hippocampus; Hypothalamus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1987
[3H]3,4-methylenedioxymethamphetamine (MDMA) interactions with brain membranes and glass fiber filter paper.
    European journal of pharmacology, 1987, Jun-26, Volume: 138, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cell Membrane; Filtration; In Vitro Techniques; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Radioligand Assay; Rats; Serotonin; Tritium

1987
Toxicity of methylenedioxymethamphetamine (MDMA) in the dog and the rat.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Body Weight; Brain; Dogs; Eating; Female; Male; N-Methyl-3,4-methylenedioxyamphetamine; Organ Size; Rats; Rats, Inbred Strains; Substance-Related Disorders

1987
Behavioral suppression following 3,4-methylenenedioxymethamphetamine.
    Life sciences, 1987, Sep-14, Volume: 41, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Dextroamphetamine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats

1987
The effect of MDA and MDMA ("Ecstasy") isomers in combination with pirenpirone on operant responding in mice.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Drug Combinations; Isomerism; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Serotonin Antagonists

1987
Incidence of recreational use of 3,4-methylenedimethoxymethamphetamine (MDMA, "ecstasy") on an undergraduate campus.
    The New England journal of medicine, 1987, Dec-10, Volume: 317, Issue:24

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; California; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Students; Substance-Related Disorders

1987
Behavioral effects of N-ethyl-3,4-methylenedioxyamphetamine (MDE; "EVE").
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Legislation, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Time Factors; United States

1987
Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Ketanserin; Kinetics; Male; Methiothepin; N-Methyl-3,4-methylenedioxyamphetamine; Piperonyl Butoxide; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase

1987
New data intensify the agony over ecstasy.
    Science (New York, N.Y.), 1988, Feb-19, Volume: 239, Issue:4842

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Haplorhini; Humans; Legislation, Drug; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Neurons; Psychotherapy; Rats; Serotonin; Substance-Related Disorders

1988
Legal limbo for ecstasy.
    Science (New York, N.Y.), 1988, Feb-19, Volume: 239, Issue:4842

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Humans; Legislation, Drug; N-Methyl-3,4-methylenedioxyamphetamine; Psychotherapy; Substance-Related Disorders

1988
The complications of 'ecstasy' (MDMA)
    JAMA, 1988, Mar-18, Volume: 259, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1988
Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat.
    Neuropharmacology, 1987, Volume: 26, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Tryptophan Hydroxylase

1987
Ecstasy returns to Schedule I.
    Science (New York, N.Y.), 1988, Apr-01, Volume: 240, Issue:4848

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Legislation, Drug; N-Methyl-3,4-methylenedioxyamphetamine

1988
Stimulus properties of 1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDA) analogs.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Dextroamphetamine; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1988
Methysergide potentiates the hyperactivity produced by MDMA in rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Drug Synergism; Male; Methysergide; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin

1988
Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration.
    Brain research, 1988, Apr-12, Volume: 446, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Amphetamines; Animals; Brain; Drug Administration Schedule; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Organ Specificity; Saimiri; Serotonin

1988
MDMA and MDA cross reactivity observed with Abbott TDx amphetamine/methamphetamine reagents.
    Clinical chemistry, 1988, Volume: 34, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Amphetamines; Cross Reactions; Female; Fluorescence Polarization; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reagent Kits, Diagnostic

1988
View from the Nation's Capital. DEA considers relaxing restrictions on medical use of marijuana.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Cannabis; Dronabinol; Drug and Narcotic Control; Humans; N-Methyl-3,4-methylenedioxyamphetamine; United States; United States Food and Drug Administration

1988
3,4-Methylenedioxymethamphetamine (MDMA) and other amphetamine derivatives.
    Journal of forensic sciences, 1988, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Alcoholic Intoxication; Amphetamines; Automobile Driving; Cause of Death; Chemical Phenomena; Chemistry; Female; Forensic Medicine; Humans; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyamphetamine

1988
The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat.
    European journal of pharmacology, 1988, Mar-29, Volume: 148, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Caudate Nucleus; Consciousness; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains

1988
Orally administered MDMA causes a long-term depletion of serotonin in rat brain.
    Brain research, 1988, Apr-26, Volume: 447, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Amphetamines; Animals; Brain; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Time Factors

1988
Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Body Temperature; Corticosterone; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists

1988
The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Brain; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred F344; Reward

1988
Drug discrimination studies with MDMA and amphetamine.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship

1988
Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites.
    European journal of pharmacology, 1988, Apr-27, Volume: 149, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Receptors, Drug

1988
Differences in the stimulus properties of 3,4-methylenedioxyamphetamine and 3,4- methylenedioxymethamphetamine in animals trained to discriminate hallucinogens from saline.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Hallucinogens; Lysergic Acid Diethylamide; Male; Mescaline; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1988
Enhancement of morphine-induced analgesia after repeated injections of methylenedioxymethamphetamine.
    Brain research, 1988, Aug-02, Volume: 457, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analgesia; Animals; Body Weight; Catecholamines; Central Nervous System; Drug Interactions; Male; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Pain; Rats; Rats, Inbred Strains; Serotonin

1988
Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; alpha-Methyltyrosine; Amphetamines; Animals; Brain; Dopamine; Hydroxydopamines; Male; Methyltyrosines; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Serotonin; Tryptophan Hydroxylase

1988
Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Time Factors

1988
Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: application to methylenedioxymethamphetamine.
    Neurotoxicology, 1988,Fall, Volume: 9, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Axons; Caudate Nucleus; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Rats; Rats, Inbred Strains; Serotonin; Tyrosine 3-Monooxygenase

1988
Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity.
    European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Dopamine; Male; Methoxyhydroxyphenylglycol; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Norepinephrine; Rats; Species Specificity

1988
Ring-substituted amphetamine interactions with neurotransmitter receptor binding sites in human cortex.
    Neuroscience letters, 1988, Dec-19, Volume: 95, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Cerebral Cortex; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Neurotransmitter

1988
Characterization of methamphetamine effects on the striatal-nigral dynorphin system.
    European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dynorphins; Hydroxydopamines; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Oxidopamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical

1988
Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1988, Volume: 1, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Behavior; Designer Drugs; Humans; Interviews as Topic; N-Methyl-3,4-methylenedioxyamphetamine; Personality; Substance-Related Disorders; Surveys and Questionnaires

1988
Advantages and disadvantages of a rapid method to train drug discrimination.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methods; N-Methyl-3,4-methylenedioxyamphetamine; Rats

1988
Serotonergic-dopaminergic mediation of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination, Psychological; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Time Factors

1988
Discriminative stimulus properties of MDA analogs.
    Biological psychiatry, 1982, Volume: 17, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1982
Pharmacologic investigation of compounds related to 3,4-methylenedioxyamphetamine (MDA).
    Substance and alcohol actions/misuse, 1984, Volume: 5, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Phenobarbital; Phenoxybenzamine; Propranolol

1984
Simultaneous determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in human hair by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, Aug-04, Volume: 670, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance-Related Disorders

1995
A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 4-Butyrolactone; Animals; Brain; Chlormethiazole; Designer Drugs; Dizocilpine Maleate; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Ondansetron; Pentobarbital; Rats; Serotonin

1994
Modeling for risk assessment of neurotoxic effects.
    Risk analysis : an official publication of the Society for Risk Analysis, 1994, Volume: 14, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Confidence Intervals; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Haplorhini; Hydroxyindoleacetic Acid; Male; Maximum Allowable Concentration; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reference Values; Risk Factors; Serotonin; Species Specificity

1994
The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype.
    British journal of pharmacology, 1995, Volume: 115, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature Regulation; Brain; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Fever; Humans; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Phenotype; Proadifen; Quinidine; Rats; Rectum; Serotonin; Serotonin Agents; Sex Factors; Tritium

1995
Serotonergic recovery after (+/-)3,4-(methylenedioxy) methamphetamine injury: observations in rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Axons; Brain Chemistry; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin

1993
5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Rats; Serotonin

1993
Effects of benzylpiperazine derivatives on the acute effects of 3,4-methylenedioxymethamphetamine in rat brain.
    Neuroscience letters, 1993, Apr-02, Volume: 152, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Desipramine; Hydroxyindoleacetic Acid; Imipramine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptosomes

1993
CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA).
    Brain research, 1994, Aug-29, Volume: 655, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Female; Humans; Injections, Intraperitoneal; Male; Mice; Mice, Transgenic; N-Methyl-3,4-methylenedioxyamphetamine; Oxygen Consumption; Sex Characteristics; Superoxide Dismutase; Superoxides

1994
Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors.
    Neuroscience letters, 1994, Aug-15, Volume: 177, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; 3T3 Cells; Animals; Cells, Cultured; Fibroblasts; Hydrolysis; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Phosphatidylinositols; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship

1994
Behavioral and developmental effects of two 3,4-methylenedioxymethamphetamine (MDMA) derivatives.
    Drug and alcohol dependence, 1994, Volume: 36, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Abnormalities, Drug-Induced; Animals; Appetitive Behavior; Arousal; Body Weight; Brain; Chick Embryo; Designer Drugs; Discrimination Learning; Dose-Response Relationship, Drug; Liver; Male; N-Methyl-3,4-methylenedioxyamphetamine; Organ Size; Rats; Structure-Activity Relationship

1994
A study of the precursors, intermediates and reaction by-products in the synthesis of 3,4-methylenedioxymethylamphetamine and its application to forensic drug analysis.
    Forensic science international, 1993, Volume: 60, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Drug and Narcotic Control; England; Forensic Medicine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1993
Persistent effects of (+/- )3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on human sleep.
    Sleep, 1993, Volume: 16, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Electroencephalography; Female; Humans; Male; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Polysomnography; Psychiatric Status Rating Scales; Respiration; Serotonin; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Substance-Related Disorders

1993
Drug-induced hyperthermia.
    Anaesthesia, 1993, Volume: 48, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Fluoxetine; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Remoxipride; Thioridazine

1993
Survival following 'Ecstasy' ingestion with a peak temperature of 42 degrees C.
    Anaesthesia, 1993, Volume: 48, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Body Temperature; Dantrolene; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1993
Comparison of conditioned taste aversions produced by MDMA and d-amphetamine.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Avoidance Learning; Designer Drugs; Dextroamphetamine; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Taste

1993
Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters.
    Molecular pharmacology, 1993, Volume: 44, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Blood Platelets; Carrier Proteins; Cattle; Cell Membrane; Chromaffin Granules; Fenfluramine; Humans; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; p-Chloroamphetamine; Reserpine; Serotonin; Serotonin Plasma Membrane Transport Proteins

1993
MDMA-like stimulus effects of alpha-ethyltryptamine and the alpha-ethyl homolog of DOM.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; alpha-Methyltyrosine; Animals; Central Nervous System Stimulants; Dextroamphetamine; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Generalization, Stimulus; Male; Methyltyrosines; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Tryptamines; Tyrosine 3-Monooxygenase

1993
Hyponatraemia and catatonic stupor after taking "ecstasy".
    BMJ (Clinical research ed.), 1993, Nov-27, Volume: 307, Issue:6916

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Catatonia; Designer Drugs; Female; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine; Unconsciousness

1993
High-pressure liquid chromatography/electrochemical detection method for monitoring MDA and MDMA in whole blood and other biological tissues.
    Journal of neuroscience methods, 1993, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Electrochemistry; Evaluation Studies as Topic; N-Methyl-3,4-methylenedioxyamphetamine

1993
Mapping toxicant-induced nervous system damage with a cupric silver stain: a quantitative analysis of neural degeneration induced by 3,4-methylenedioxymethamphetamine.
    NIDA research monograph, 1993, Volume: 136

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Silver Staining

1993
Cerebral infarction in association with Ecstasy abuse.
    Postgraduate medical journal, 1993, Volume: 69, Issue:817

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cerebral Infarction; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1993
Intracranial haemorrhage associated with ingestion of 'ecstasy'.
    Archives of emergency medicine, 1993, Volume: 10, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cerebral Hemorrhage; Craniotomy; Designer Drugs; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neurologic Examination; Tomography, X-Ray Computed

1993
Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Designer Drugs; Enzyme Induction; Female; Isoenzymes; Kinetics; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Phenobarbital; Rats; Rats, Sprague-Dawley; Stereoisomerism

1994
Methylenedioxyamphetamine ('Ecstasy') associated keratopathy.
    Eye (London, England), 1993, Volume: 7 ( Pt 6)

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Chloramphenicol; Corneal Diseases; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1993
Hyponatraemia after ingestion of ecstasy.
    BMJ (Clinical research ed.), 1994, Feb-05, Volume: 308, Issue:6925

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Humans; Hyponatremia; N-Methyl-3,4-methylenedioxyamphetamine

1994
Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine.
    Journal of neurochemistry, 1994, Volume: 62, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluorobenzenes; Homovanillic Acid; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin

1994
Catatonic stupor after "ecstasy".
    BMJ (Clinical research ed.), 1994, Mar-12, Volume: 308, Issue:6930

    Topics: 3,4-Methylenedioxyamphetamine; Catatonia; Designer Drugs; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1994
MDMA enhances associative and nonassociative learning in the rabbit.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Association Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Female; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nictitating Membrane; Physical Stimulation; Rabbits; Stimulation, Chemical

1994
Contrasting effects of dopaminergic blockade on MDMA and d-amphetamine conditioned taste aversions.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Avoidance Learning; Benzazepines; Dextroamphetamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Salicylamides; Taste

1994
Treating MDMA ('Ecstasy') toxicity.
    Anaesthesia, 1994, Volume: 49, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Poisoning

1994
A fatal overdose with 3,4-methylenedioxyamphetamine derivatives.
    Forensic science international, 1994, Volume: 64, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Cannabinoids; Cannabis; Designer Drugs; Drug Overdose; Fatal Outcome; Humans; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Postmortem Changes; Substance-Related Disorders

1994
The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6).
    Biochemical pharmacology, 1994, Mar-29, Volume: 47, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; N-Methyl-3,4-methylenedioxyamphetamine; NADP; Saccharomyces cerevisiae; Transfection

1994
In vitro release of [3H]5-hydroxytryptamine from fetal and maternal brain by drugs of abuse.
    Brain research. Developmental brain research, 1994, Mar-18, Volume: 78, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Cocaine; Designer Drugs; Female; Fenfluramine; In Vitro Techniques; Maternal-Fetal Exchange; N-Methyl-3,4-methylenedioxyamphetamine; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Substance-Related Disorders; Synaptosomes

1994
Effects of designer drugs on the chicken embryo and 1-day-old chicken.
    Brain research bulletin, 1994, Volume: 34, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Animals, Newborn; Body Weight; Chick Embryo; Chickens; Designer Drugs; Dextroamphetamine; Embryonic and Fetal Development; Female; Models, Biological; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Water

1994
Increasing use of "Ecstasy" (MDMA) and other hallucinogens on a college campus.
    Journal of American college health : J of ACH, 1994, Volume: 42, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cross-Sectional Studies; Designer Drugs; Hallucinogens; Humans; Louisiana; N-Methyl-3,4-methylenedioxyamphetamine; Students; Substance-Related Disorders; Surveys and Questionnaires; Universities

1994
Microwave-induced rapid preparation of fluoro-derivatives of amphetamine, methamphetamine, and 3,4-methylenedioxymethamphetamine for GC-MS confirmation assays.
    Clinical chemistry, 1994, Volume: 40, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Calibration; Designer Drugs; Fluorides; Gas Chromatography-Mass Spectrometry; Methamphetamine; Microwaves; N-Methyl-3,4-methylenedioxyamphetamine; Phentermine

1994
Metabolic and thermoregulatory responses of the rat maintained in acrylic or wire-screen cages: implications for pharmacological studies.
    Physiology & behavior, 1994, Volume: 56, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acclimatization; Animals; Body Temperature Regulation; Dose-Response Relationship, Drug; Energy Metabolism; Housing, Animal; Male; Methylmethacrylate; Methylmethacrylates; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Stainless Steel; Water Loss, Insensible

1994
Behavioral effects of the highly selective serotonin releasing agent 5-methoxy-6-methyl-2-aminoindan.
    European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Discrimination Learning; Dose-Response Relationship, Drug; Indans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stereoisomerism

1994
A case of toxic psychosis induced by 'eve' (3,4-methylene-dioxyethylam-phetamine)
    Archives of general psychiatry, 1993, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Substance-Related Disorders

1993
Effects of cortical serotonin depletion induced by 3,4-methylenedioxymethamphetamine (MDMA) on behavior, before and after additional cholinergic blockade.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Atropine; Behavior, Animal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prosencephalon; Random Allocation; Rats; Rats, Sprague-Dawley; Serotonin

1993
Treatment of 'ecstasy' overdose with dantrolene.
    Anaesthesia, 1993, Volume: 48, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Drug Overdose; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1993
'Ecstasy' misuse--overdose or normal dose?
    Anaesthesia, 1993, Volume: 48, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Drug Overdose; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1993
Treatment of 'ecstasy' overdose with dantrolene.
    Anaesthesia, 1993, Volume: 48, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Drug Overdose; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1993
Ecstasy and dantrolene.
    BMJ (Clinical research ed.), 1993, Jan-09, Volume: 306, Issue:6870

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Drug Overdose; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1993
M.D.M.A. ("Ecstasy"); a case of possible drug-induced psychosis.
    Irish journal of medical science, 1993, Volume: 162, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Designer Drugs; Humans; Ireland; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Time Factors

1993
Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Cortex; Flunarizine; Haloperidol; Hippocampus; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nifedipine; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Stereotyped Behavior; Verapamil

1993
Dantrolene and 'ecstasy' overdose.
    Anaesthesia, 1993, Volume: 48, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Dantrolene; Designer Drugs; Fever; Humans; N-Methyl-3,4-methylenedioxyamphetamine

1993
Simultaneous identification of amphetamine and its derivatives in urine using HPLC-UV.
    International journal of legal medicine, 1993, Volume: 105, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Treatment Centers; Substance-Related Disorders; Ultraviolet Rays

1993
[Acute liver failure caused by methylenedioxymethamphetamine ('ecstasy')].
    Nederlands tijdschrift voor geneeskunde, 1993, Apr-03, Volume: 137, Issue:14

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Designer Drugs; Female; Humans; Liver Failure, Acute; N-Methyl-3,4-methylenedioxyamphetamine

1993
Interactions of methylenedioxymethamphetamine with monoamine transmitter release mechanisms in rat brain slices.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Biogenic Monoamines; Brain; Calcium; Electric Stimulation; Female; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Pargyline; Rats; Rats, Sprague-Dawley; Reserpine

1993
Drug effects on distribution of [3H]3,4-methylenedioxymethamphetamine in mice.
    European journal of pharmacology, 1993, Apr-01, Volume: 228, Issue:5-6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Drug Interactions; Injections, Intravenous; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Tissue Distribution

1993
EMIT-d.a.u. monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA).
    Forensic science international, 1993, Volume: 59, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Cross Reactions; Designer Drugs; Gas Chromatography-Mass Spectrometry; Immunoassay; Injections, Intravenous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Sensitivity and Specificity; Stereoisomerism

1993
'Ecstasy' induced pneumomediastinum.
    Journal of the Royal Society of Medicine, 1993, Volume: 86, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Designer Drugs; Humans; Male; Mediastinal Emphysema; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1993
'Ecstasy' ingestion: a case report of severe complications.
    Journal of the Royal Society of Medicine, 1993, Volume: 86, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Acute Kidney Injury; Adult; Amphetamine; Designer Drugs; Disseminated Intravascular Coagulation; Humans; Liver; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rhabdomyolysis; Substance-Related Disorders

1993
Serotonin1B receptor activation mimics behavioral effects of presynaptic serotonin release.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Caffeine; Designer Drugs; Dopamine Agents; Dose-Response Relationship, Drug; Fluoxetine; Indoles; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Receptor Agonists; Synapses

1993
Ecstasy and Whizz at a rave resulting in a major burn plus complications.
    Burns : journal of the International Society for Burn Injuries, 1993, Volume: 19, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Burns; Designer Drugs; Drug Overdose; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1993
The interactions of MK-801 with the amphetamine analogues D-methamphetamine (D-METH), 3,4-methylenedioxymethamphetamine (D-MDMA) or D-fenfluramine (D-FEN): neural damage and neural protection.
    Annals of the New York Academy of Sciences, 1993, May-28, Volume: 679

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biomarkers; Brain; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Female; Fenfluramine; Glial Fibrillary Acidic Protein; Hippocampus; Methamphetamine; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxins

1993
Fatal intoxication involving etryptamine.
    Journal of forensic sciences, 1993, Volume: 38, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Tryptamines

1993
Point-counterpoint. A reader writes: speed, ice, and ecstasy.
    Pediatrics in review, 1993, Volume: 14, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adolescent Behavior; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1993
Integrative transporter-mediated release from cytoplasmic and vesicular 5-hydroxytryptamine stores in cultured neurons.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Stem; Carrier Proteins; Cells, Cultured; Clorgyline; Female; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurons; Nimodipine; p-Chloroamphetamine; Pregnancy; Rats; Rats, Sprague-Dawley; Reserpine; Selegiline; Serotonin; Serotonin Plasma Membrane Transport Proteins

1993
Ecstasy intoxication: appreciation of complications and the role of dantrolene.
    Anaesthesia, 1993, Volume: 48, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Dantrolene; Designer Drugs; Fever; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1993
Effect of acute monoamine depletion on 3,4-methylenedioxymethamphetamine-induced neurotoxicity.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; alpha-Methyltyrosine; Animals; Axons; Biogenic Monoamines; Brain Chemistry; Designer Drugs; Dialysis; Dopamine; Fenclonine; Male; Methyltyrosines; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nervous System Diseases; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Stereotaxic Techniques; Tyrosine 3-Monooxygenase

1993
Ecstasy--dental implications.
    British dental journal, 1993, Jul-10, Volume: 175, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Carbonated Beverages; Dental Caries; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sucrose; Tooth Erosion; Xerostomia

1993
'Rave' to the grave.
    Forensic science international, 1993, Volume: 60, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Substance-Related Disorders; Suicide

1993
Reinforcing subjective effects of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: clinical evidence.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Arousal; Designer Drugs; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Female; Fluoxetine; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Reinforcement, Psychology; Substance-Related Disorders

1993
3,4-Methylenedioxymethamphetamine, serotonin and memory.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Desipramine; Immunohistochemistry; Learning; Male; Memory; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Scopolamine; Serotonin

1993
Stereoselective disposition: enantioselective quantitation of 3,4-(methylenedioxy) methamphetamine and three of its metabolites by gas chromatography/electron capture negative ion chemical ionization mass spectrometry.
    Biological mass spectrometry, 1993, Volume: 22, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Gas Chromatography-Mass Spectrometry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

1993
Effects of ritanserin on the 3,4-methylenedioxymethamphetamine-induced decrease in striatal serotonin concentration and on the increase in striatal neurotensin and dynorphin A concentrations.
    Biochemical pharmacology, 1993, Aug-17, Volume: 46, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Designer Drugs; Dynorphins; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotensin; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin

1993
["Ecstasy"-induced psychotic depersonalization syndrome].
    Der Nervenarzt, 1993, Volume: 64, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Combined Modality Therapy; Depersonalization; Designer Drugs; Dose-Response Relationship, Drug; Female; Fluvoxamine; Humans; Lorazepam; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Suicide; Suicide Prevention

1993
Synthesis markers in illegally manufactured 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine.
    International journal of legal medicine, 1993, Volume: 106, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, Gas; Chromatography, Thin Layer; Designer Drugs; Drug and Narcotic Control; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Magnetic Resonance Spectroscopy; N-Methyl-3,4-methylenedioxyamphetamine

1993
5-HT2 receptor-mediated potentiation of dopamine synthesis and central serotonergic deficits.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hippocampus; Hydrazines; Indans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Cerebral venous sinus thrombosis induced by 'ecstasy'.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Female; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sinus Thrombosis, Intracranial

1993
Subarachnoid haemorrhage associated with MDMA abuse.
    Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; N-Methyl-3,4-methylenedioxyamphetamine; Subarachnoid Hemorrhage

1993
Analysis of the enantiomers of 3,4-methylenedioxy-N-ethylamphetamine (MDE, "Eve") and its metabolite 3,4-methylenedioxyamphetamine (MDA) in rat brain.
    Journal of pharmacological and toxicological methods, 1995, Volume: 34, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, Gas; Designer Drugs; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

1995
Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion.
    Biochemical pharmacology, 1996, Mar-22, Volume: 51, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Dose-Response Relationship, Drug; Female; Hallucinogens; Male; Methylation; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Serotonin; Sex Factors; Species Specificity; Stereoisomerism

1996
Pathology of deaths associated with "ecstasy" and "eve" misuse.
    Journal of clinical pathology, 1996, Volume: 49, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Brain; Humans; Liver; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1996
"ADAM' or "EVE'?--a toxicological conundrum.
    Forensic science international, 1996, Jan-12, Volume: 77, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine; Female; Homicide; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1996
Use of drugs at 'raves'.
    Scottish medical journal, 1995, Volume: 40, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Catha; Central Nervous System Stimulants; Dancing; Designer Drugs; Female; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Plant Extracts; Scotland; Substance-Related Disorders; Surveys and Questionnaires

1995
Fatal poisoning by MDMA (ecstasy) and MDEA: a case report.
    International journal of legal medicine, 1996, Volume: 108, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Capillaries; Designer Drugs; Drug Overdose; Fluorescent Antibody Technique; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Kidney Tubules; Lung; Myoglobinuria; N-Methyl-3,4-methylenedioxyamphetamine; Poisoning; Pulmonary Embolism

1996
Adam and Eve make love. Analysis of the enantiomers of 3,4-methylenedioxy-N-ethylamphetamine (MDE, "Eve") and its metabolite 3,4-methylenedioxyamphetamine (MDA) in rat brain.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Stereoisomerism

1996
Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers.
    International journal of legal medicine, 1996, Volume: 108, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Accidents, Traffic; Amphetamine; Cocaine; Crime; Designer Drugs; Dronabinol; Expert Testimony; Gas Chromatography-Mass Spectrometry; Hair; Heroin Dependence; Humans; Illicit Drugs; Marijuana Abuse; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Opioid-Related Disorders; Psychotropic Drugs; Sensitivity and Specificity

1996
Identification of N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) in urine from drug users.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Calibration; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Serotonin; Substance-Related Disorders; Sweden

1996
Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by headspace/solid phase micro-extraction (SPME) and GC/MS.
    Forensic science international, 1996, Dec-27, Volume: 83, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine

1996
Interlaboratory comparison of quantitative determination of amphetamine and related compounds in hair samples.
    Forensic science international, 1997, Jan-17, Volume: 84, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Central Nervous System Stimulants; France; Gas Chromatography-Mass Spectrometry; Germany; Hair; Hallucinogens; Humans; Laboratories; Male; N-Methyl-3,4-methylenedioxyamphetamine; Quality Control; Spain; Substance Abuse Detection; United States

1997
Hair analysis for drug abuse. XV. Disposition of 3, 4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA abuse.
    Forensic science international, 1997, Jan-17, Volume: 84, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Lactates; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Substance Abuse Detection; Substance-Related Disorders

1997
[Epidemiology of designer drug use in Spain].
    Medicina clinica, 1997, Jan-18, Volume: 108, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Cocaine; Designer Drugs; Female; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Spain; Substance-Related Disorders

1997
Enantioselective determination of 3,4-methylene-dioxymethamphetamine and two of its metabolites in human urine by cyclodextrin-modified capillary zone electrophoresis.
    Electrophoresis, 1997, Volume: 18, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Cyclodextrins; Dopamine; Electrophoresis, Capillary; Humans; Methamphetamine; Molecular Conformation; N-Methyl-3,4-methylenedioxyamphetamine

1997
Biochemical implications of ecstasy toxicity.
    Annals of clinical biochemistry, 1997, Volume: 34 ( Pt 4)

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Creatine Kinase; Creatinine; Hemoglobins; Humans; Isoenzymes; Liver Function Tests; Male; N-Methyl-3,4-methylenedioxyamphetamine; Renal Insufficiency; Substance-Related Disorders; Urea

1997
Assessment of the MDA and MDMA optical isomers in a stimulant-hallucinogen discrimination.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cocaine; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Food; Generalization, Psychological; Hallucinogens; Lysergic Acid Diethylamide; Male; Mescaline; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Stereoisomerism

1997
Ecstasy: creatinine kinase.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Creatine Kinase; Dantrolene; Designer Drugs; Fever; Humans; Multiple Organ Failure; Muscle Relaxants, Central; Muscle, Skeletal; N-Methyl-3,4-methylenedioxyamphetamine; Paraplegia

1997
Sensitive and selective determination of methylenedioxylated amphetamines by high-performance liquid chromatography with fluorimetric detection.
    Journal of chromatography. A, 1997, Nov-07, Volume: 787, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Tablets

1997
Detection of designer drugs in human hair by ion mobility spectrometry (IMS).
    Forensic science international, 1998, Jun-08, Volume: 94, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Forensic Medicine; Hair; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion; Substance-Related Disorders

1998
[Entactogenic drugs "ecstasy" (MDMA), "eve" (MDE) and other ring-substituted methamphetamine derivatives. A new class of substances among illegal designer drugs?].
    Der Nervenarzt, 1997, Volume: 68, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Risk Factors

1997
Amphetamines induce apoptosis and regulation of bcl-x splice variants in neocortical neurons.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Alternative Splicing; Amphetamines; Animals; Apoptosis; bcl-X Protein; Dextroamphetamine; DNA Fragmentation; Gene Expression Regulation; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neocortex; Neurons; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

1999
The acute effect in rats of 3,4-methylenedioxyethamphetamine (MDEA, "eve") on body temperature and long term degeneration of 5-HT neurones in brain: a comparison with MDMA ("ecstasy").
    Pharmacology & toxicology, 1999, Volume: 84, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Fever; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Paroxetine; Rats; Serotonin; Time Factors; Visual Cortex

1999
Simultaneous determination of amphetamine, methamphetamine, methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methylenedioxyethylamphetamine (MDEA) enantiomers by GC-MS.
    Journal of analytical toxicology, 1999, Volume: 23, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection; Time Factors; Urine

1999
Adam (MDMA) and Eve (MDEA) misuse: an immunohistochemical study on three fatal cases.
    Forensic science international, 1999, Sep-30, Volume: 104, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Disseminated Intravascular Coagulation; Fatal Outcome; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Myoglobinuria; N-Methyl-3,4-methylenedioxyamphetamine; Rhabdomyolysis

1999
The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.
    Cell biology and toxicology, 1999, Volume: 15, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biomarkers; Brain; Brain Diseases; Cytosol; Deoxyepinephrine; Dose-Response Relationship, Drug; Fetus; Glial Fibrillary Acidic Protein; Glutathione; L-Lactate Dehydrogenase; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin; Serotonin Agents; Spheroids, Cellular

1999
Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Avoidance Learning; Carrier Proteins; Designer Drugs; Frontal Lobe; Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins

2000
The use of supercritical fluid extraction for the determination of amphetamines in hair.
    Forensic science international, 2000, Jan-10, Volume: 107, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Reference Values; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

2000
Automated determination of 'Ecstasy' and amphetamines in urine by SPME and capillary gas chromatography after propylchloroformate derivatisation.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 19, Issue:3-4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Esters; Evaluation Studies as Topic; Formates; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection

1999
An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats.
    Immunopharmacology, 2000, Volume: 46, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Concanavalin A; Cytokines; Female; Fenfluramine; Immunity; Leukocyte Count; Lipopolysaccharides; Lymphocyte Activation; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Agents

2000
Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice.
    Psychopharmacology, 2000, Volume: 149, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reflex, Startle; Serotonin; Serotonin Agents; Serotonin Antagonists

2000
High-resolution solid state 13C nuclear magnetic resonance spectra of 3,4-methylenedioxyamphetamine hydrochloride and related compounds and their mixtures with lactose.
    Solid state nuclear magnetic resonance, 2000, Volume: 16, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Carbon Isotopes; Crystallization; Ephedrine; Hydrogen Bonding; Lactose; Magnetic Resonance Spectroscopy; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solutions; Stereoisomerism

2000
Determination of the designer drugs 3, 4-methylenedioxymethamphetamine, 3,4-methylenedioxyethylamphetamine, and 3,4-methylenedioxyamphetamine with HPLC and fluorescence detection in whole blood, serum, vitreous humor, and urine.
    Clinical chemistry, 2000, Volume: 46, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Humans; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Substance Abuse Detection; Vitreous Body

2000
Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection.
    Fresenius' journal of analytical chemistry, 2000, Volume: 367, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Acetonitriles; Amphetamines; Cocaine; Electrophoresis, Capillary; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Substance Abuse Detection

2000
Stereospecific analysis of ecstasy-like N-ethyl-3,4-methylenedioxyamphetamine and its metabolites in humans.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Feb-10, Volume: 751, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity

2001
[Analysis of MDMA and its metabolites in urine by GC and GC/MS].
    Fa yi xue za zhi, 1998, Volume: 14, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Lactates; N-Methyl-3,4-methylenedioxyamphetamine

1998
Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Brain; Dopamine; Fever; Locomotion; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin; Serotonin Agents

2001
Sensitive determination of methylenedioxylated amphetamines by liquid chromatography.
    The Analyst, 2001, Volume: 126, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Liquid; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine

2001
Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase.
    Chemical research in toxicology, 2001, Volume: 14, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Cutaneous; Animals; Brain; Endothelium; Enzyme Inhibitors; gamma-Glutamyltransferase; Humans; Isoxazoles; Male; Models, Molecular; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents

2001
Usefulness of saliva for measurement of 3,4-methylenedioxymethamphetamine and its metabolites: correlation with plasma drug concentrations and effect of salivary pH.
    Clinical chemistry, 2001, Volume: 47, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Lactates; Male; N-Methyl-3,4-methylenedioxyamphetamine; Saliva; Substance Abuse Detection

2001
Stability study of the designer drugs "MDA, MDMA and MDEA" in water, serum, whole blood, and urine under various storage temperatures.
    Forensic science international, 2001, Dec-15, Volume: 124, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Designer Drugs; Drug Stability; Drug Storage; Forensic Medicine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Water

2001
Application of SERS spectroscopy to the identification of (3,4-methylenedioxy)amphetamine in forensic samples utilizing matrix stabilized silver halides.
    The Analyst, 2001, Volume: 126, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spectrum Analysis, Raman

2001
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Fever; Hallucinogens; Hippocampus; Male; Methysergide; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Remoxipride; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2002
Distribution study of 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine in a fatal overdose.
    Journal of analytical toxicology, 2002, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Chromatography, High Pressure Liquid; Fatal Outcome; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Spectrometry, Mass, Electrospray Ionization; Vitreous Body

2002
Determination of paramethoxyamphetamine and other amphetamine-related designer drugs by liquid chromatography/sonic spray ionization mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Chromatography, High Pressure Liquid; Designer Drugs; Forensic Medicine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2002
Quantitation of amphetamine, methamphetamine, and their methylenedioxy derivatives in urine by solid-phase microextraction coupled with electrospray ionization-high-field asymmetric waveform ion mobility spectrometry-mass spectrometry.
    Analytical chemistry, 2002, Jul-01, Volume: 74, Issue:13

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Central Nervous System Stimulants; Hallucinogens; Humans; Indicators and Reagents; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2002
Isotopic characterisation of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethylamphetamine (ecstasy).
    The Analyst, 2002, Volume: 127, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Drug and Narcotic Control; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Magnetic Resonance Spectroscopy; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity

2002
Ecstasy counteracts catalepsy in rats, an anti-parkinsonian effect?
    Neuroscience letters, 2002, Sep-27, Volume: 330, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Animals; Catalepsy; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley

2002
Rewarding effects of the optical isomers of 3,4-methylenedioxy-methylamphetamine ('Ecstasy') and 3,4-methylenedioxy-ethylamphetamine ('Eve') measured by conditioned place preference in rats.
    Neuroscience letters, 2002, Sep-27, Volume: 330, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Hallucinogens; Isomerism; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Social Isolation

2002
Immunohistochemical demonstration of the amphetamine derivatives 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) in human post-mortem brain tissues and the pituitary gland.
    International journal of legal medicine, 2003, Volume: 117, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Brain; Chromatography, High Pressure Liquid; Fatal Outcome; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pituitary Gland; Substance Abuse Detection; Tissue Distribution

2003
Hypothalamic-pituitary-thyroid axis and sympathetic nervous system involvement in hyperthermia induced by 3,4-methylenedioxymethamphetamine (Ecstasy).
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic alpha-Antagonists; Animals; Drug Interactions; Fever; Hypophysectomy; Hypothalamo-Hypophyseal System; Male; Muscle, Skeletal; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Pindolol; Prazosin; Rats; Rats, Sprague-Dawley; Rectum; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Thyroid Gland; Thyroxine

2003
Development of a rapid and sensitive method for the quantitation of amphetamines in human plasma and oral fluid by LC-MS-MS.
    Journal of analytical toxicology, 2003, Volume: 27, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ephedrine; Humans; Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Saliva; Substance Abuse Detection

2003
3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro.
    Molecular pharmacology, 2003, Volume: 63, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cell Division; Cells, Cultured; COS Cells; Fenfluramine; Heart Valve Diseases; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Norfenfluramine; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Agents

2003
Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Citalopram; Dopamine; Fenclonine; Functional Laterality; Hallucinogens; Male; Medial Forebrain Bundle; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2003
Confirmation of amphetamine, methamphetamine, MDA and MDMA in urine samples using disk solid-phase extraction and gas chromatography-mass spectrometry after immunoassay screening.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Jul-25, Volume: 792, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Gas Chromatography-Mass Spectrometry; Immunoassay; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine

2003
Tissue concentrations of MDMA and its metabolite MDA in three fatal cases of overdose.
    Forensic science international, 2003, Aug-12, Volume: 135, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Drug Overdose; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Tissue Distribution

2003
Actions of amphetamine derivatives and cathinone at the noradrenaline transporter.
    European journal of pharmacology, 2003, Aug-22, Volume: 476, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Alkaloids; Amphetamines; Animals; Cerebral Cortex; Cocaine; Competitive Bidding; Fluoxetine; In Vitro Techniques; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Wistar; Symporters

2003
Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
    Brain research, 2003, Oct-17, Volume: 987, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Cytochrome P-450 CYP2D6; Deoxyepinephrine; Female; Glutathione; Humans; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism

2003
Death rates from ecstasy (MDMA, MDA) and polydrug use in England and Wales 1996-2002.
    Human psychopharmacology, 2003, Volume: 18, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine-Related Disorders; Benzodiazepines; Cannabinoids; Cocaine; Drug Interactions; England; Ethanol; Female; Hallucinogens; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Wales

2003
Identification of some N-hydroxylated metabolites of (+/-)-3,4-methylenedioxymethamphetamine in horse urine by gas chromatography-mass spectrometry.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Animals; Chromatography, Thin Layer; Designer Drugs; Gas Chromatography-Mass Spectrometry; Hallucinogens; Horses; Hydrolysis; Ions; Male; Mass Spectrometry; Models, Chemical; N-Methyl-3,4-methylenedioxyamphetamine; Oxygen; Spectrometry, Mass, Electrospray Ionization

2003
Putting an Ecstasy test kit to the test: harm reduction or harm induction?
    Pharmacotherapy, 2003, Volume: 23, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Tablets

2003
P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine and paramethoxyamphetamine.
    Addiction biology, 2003, Volume: 8, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Amphetamines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Designer Drugs; Dose-Response Relationship, Drug; Drug Interactions; Fluoresceins; Fluorometry; Gene Expression; Genes, MDR; Humans; LLC-PK1 Cells; N-Methyl-3,4-methylenedioxyamphetamine; Swine; Transfection

2003
Evaluation of ephedrine, pseudoephedrine and phenylpropanolamine concentrations in human urine samples and a comparison of the specificity of DRI amphetamines and Abuscreen online (KIMS) amphetamines screening immunoassays.
    Journal of forensic sciences, 2004, Volume: 49, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Ephedrine; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Immunoassay; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Online Systems; Phenylpropanolamine; Reagent Kits, Diagnostic; Substance Abuse Detection; Sympathomimetics

2004
Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purity.
    Psychopharmacology, 2004, Volume: 173, Issue:3-4

    Topics: 3,4-Methylenedioxyamphetamine; Drug Combinations; Drug Contamination; Hallucinogens; History, 20th Century; History, 21st Century; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Tablets

2004
Interpretation of a 3,4-methylenedioxymethamphetamine (MDMA) blood level: discussion by means of a distribution study in two fatalities.
    Forensic science international, 2004, May-10, Volume: 141, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Bile; Chromatography, High Pressure Liquid; Drug Overdose; Forensic Medicine; Hallucinogens; Humans; Kidney; Liver; Lung; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Pituitary Gland; Postmortem Changes; Psoas Muscles; Stomach; Tissue Distribution; Vitreous Body

2004
Application of ORAL.screen saliva drug test for the screening of methamphetamine, MDMA, and MDEA incorporated in hair.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Forensic Medicine; Hair; Humans; Immunoassay; Immunochemistry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reagent Kits, Diagnostic; Saliva; Substance Abuse Detection

2004
Thioether metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine inhibit human serotonin transporter (hSERT) function and simultaneously stimulate dopamine uptake into hSERT-expressing SK-N-MC cells.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biological Transport; Dopamine; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Reactive Oxygen Species; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Transfection; Tumor Cells, Cultured

2004
Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamines; Chromatography, High Pressure Liquid; Clinical Chemistry Tests; Enzyme Multiplied Immunoassay Technique; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Male; Methamphetamine; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Nanostructures; Predictive Value of Tests; Sensitivity and Specificity; Substance-Related Disorders

2004
Determination of MDMA, MDEA and MDA in urine by high performance liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Nov-05, Volume: 811, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

2004
Use of MDA (the "love drug") and methamphetamine in Toronto by unsuspecting users of ecstasy (MDMA).
    Journal of forensic sciences, 2004, Volume: 49, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Canada; Cocaine; Dopamine Uptake Inhibitors; Drug Contamination; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Illicit Drugs; Male; Methamphetamine; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine

2004
Enantiomeric separation and quantitation of (+/-)-amphetamine, (+/-)-methamphetamine, (+/-)-MDA, (+/-)-MDMA, and (+/-)-MDEA in urine specimens by GC-EI-MS after derivatization with (R)-(-)- or (S)-(+)-alpha-methoxy-alpha-(trifluoromethy)phenylacetyl chlor
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Gas; Chromatography, Ion Exchange; Humans; Indicators and Reagents; Methamphetamine; Military Personnel; N-Methyl-3,4-methylenedioxyamphetamine; Quaternary Ammonium Compounds; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Abuse Detection

2004
The prevalence of MDMA/MDA in both hair and urine in drug users.
    Forensic science international, 2005, Aug-11, Volume: 152, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Female; Fluorescence Polarization Immunoassay; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Urinalysis

2005
Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection.
    Forensic science international, 2005, Jun-10, Volume: 150, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Forensic Medicine; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Saliva; Spectrometry, Fluorescence; Substance Abuse Detection

2005
Pharmacokinetic profile of single and repeated oral doses of MDMA in squirrel monkeys: relationship to lasting effects on brain serotonin neurons.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Analysis of Variance; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Electrochemistry; Female; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Protein Binding; Radiopharmaceuticals; Saimiri; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors

2006
Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDMA.
    Clinical chemistry, 2005, Volume: 51, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection; Time Factors

2005
Ecstasy--deadly risk even outside rave parties.
    Forensic science international, 2005, Oct-29, Volume: 153, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Asphyxia; Brain Edema; Cannabinoids; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Heart Ventricles; Hemorrhage; Humans; Hypoxia; Liver; N-Methyl-3,4-methylenedioxyamphetamine; Pulmonary Edema; Shock

2005
Comparison of the use of aqueous and nonaqueous buffers in association with cyclodextrin for the chiral separation of 3,4-methylenedioxymethamphetamine and related compounds.
    Electrophoresis, 2005, Volume: 26, Issue:20

    Topics: 3,4-Methylenedioxyamphetamine; beta-Cyclodextrins; Buffers; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; N-Methyl-3,4-methylenedioxyamphetamine; Solvents; Stereoisomerism

2005
An announced suicide with ecstasy.
    International journal of legal medicine, 2007, Volume: 121, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Austria; Autopsy; Drug Combinations; Drug Overdose; Forensic Toxicology; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Suicide

2007
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Fever; Hallucinogens; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Seizures; Serotonin

2006
Development and application of a high-performance liquid chromatography method using monolithic columns for the analysis of ecstasy tablets.
    Journal of chromatography. A, 2006, Jul-07, Volume: 1120, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical

2006
Effects of MDMA, MDA and MDEA on blood pressure, heart rate, locomotor activity and body temperature in the rat involve alpha-adrenoceptors.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Aorta; Blood Pressure; Body Temperature; Heart Rate; Imidazoles; Indoles; Isoindoles; Male; Motor Activity; Muscle Contraction; Muscle, Smooth; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Time Factors; Vas Deferens

2006
Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994-2003).
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Cause of Death; Crime; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug and Narcotic Control; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Statistics as Topic; United Kingdom

2006
Prostaglandin H synthase-catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Amphetamines; Animals; Aspirin; Brain; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Female; Free Radicals; Methamphetamine; Mice; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Psychomotor Performance; Synapses

2006
Chiral separation and quantification of R/S-amphetamine, R/S-methamphetamine, R/S-MDA, R/S-MDMA, and R/S-MDEA in whole blood by GC-EI-MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Oct-02, Volume: 842, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Gas; Humans; Methamphetamine; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Abuse Detection

2006
Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine.
    Clinical chemistry, 2006, Volume: 52, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Substance Abuse Detection

2006
Effects of (+/-)3,4-methylenedioxymethamphetamine, (+/-)3,4-methylenedioxyamphetamine and methamphetamine on temperature and activity in rhesus macaques.
    Neuroscience, 2006, Oct-13, Volume: 142, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature; Dose-Response Relationship, Drug; Hallucinogens; Macaca mulatta; Male; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Time Factors

2006
A simple and sensitive HPLC-fluorescence method for quantification of MDMA and MDA in blood with 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as a label.
    Biomedical chromatography : BMC, 2006, Volume: 20, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Benzoates; Chromatography, High Pressure Liquid; Fluorescence; Fluorescent Dyes; Humans; Imidazoles; N-Methyl-3,4-methylenedioxyamphetamine; Rats

2006
Distribution of methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) in postmortem and antemortem specimens.
    Journal of analytical toxicology, 2006, Volume: 30, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Diagnosis; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Substance-Related Disorders

2006
Selection and optimization of hydrolysis conditions for the quantification of urinary metabolites of MDMA.
    Journal of analytical toxicology, 2006, Volume: 30, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Dopamine; Forensic Toxicology; Glucuronidase; Hallucinogens; Humans; Hydrochloric Acid; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection

2006
Time-resolved hair analysis of MDMA enantiomers by GC/MS-NCI.
    Forensic science international, 2007, Oct-25, Volume: 172, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Biomarkers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Hair; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Time Factors

2007
Four years' experience in external proficiency testing programs for hair testing of drugs of abuse in Italy (HAIRVEQ) and comparison with the Society of Hair Testing program in 2005.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Clinical Laboratory Techniques; Cocaine; Codeine; False Negative Reactions; False Positive Reactions; Forensic Medicine; Hair; Humans; Italy; Laboratories; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Opioid Peptides; Program Evaluation; Reproducibility of Results; Spain; Statistical Distributions; Substance Abuse Detection; Time Factors

2007
Fatality due to the use of a designer drug MDMA (Ecstasy).
    Legal medicine (Tokyo, Japan), 2007, Volume: 9, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Autopsy; Chromatography, Liquid; Designer Drugs; Fatal Outcome; Hair; Hallucinogens; Humans; Liver; Male; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Poisoning; Substance-Related Disorders

2007
Ethanol-MDMA interactions in rats: the importance of interval between repeated treatments in biobehavioral tolerance and sensitization to the combination.
    Psychopharmacology, 2007, Volume: 192, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Body Temperature; Brain; Central Nervous System Depressants; Drug Interactions; Drug Tolerance; Ethanol; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Long-Evans

2007
Neurotoxicity mechanisms of thioether ecstasy metabolites.
    Neuroscience, 2007, Jun-08, Volume: 146, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Adenosine Triphosphate; Animals; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Deoxyepinephrine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Free Radical Scavengers; Glutathione; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Wistar; Temperature; Time Factors

2007
Sensitive determination of MDMA and its metabolite MDA in rat blood and brain microdialysates by HPLC with fluorescence detection.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Benzoates; Blood Chemical Analysis; Brain Chemistry; Calibration; Chromatography, High Pressure Liquid; Fluorescent Dyes; Imidazoles; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Plasma; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection

2007
Analysis of MDMA and its metabolites in urine and plasma following a neurotoxic dose of MDMA.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biotransformation; Calibration; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Rats; Reproducibility of Results; Toxicology

2007
Direct determination of glucuronide and sulfate of 4-hydroxy-3-methoxymethamphetamine, the main metabolite of MDMA, in human urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-15, Volume: 857, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Calibration; Designer Drugs; Gas Chromatography-Mass Spectrometry; Glucuronides; Hallucinogens; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Sulfates

2007
Validated liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxym
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Calibration; Chromatography, Liquid; Deoxyepinephrine; Hallucinogens; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization

2007
Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Alcohol Oxidoreductases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Caco-2 Cells; Cytochrome P-450 CYP2D6; Cytochrome P450 Family 2; Drug Interactions; Fluoxetine; Humans; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

2008
Supported liquid-liquid extraction of the active ingredient (3,4-methylenedioxymethylamphetamine) from ecstasy tablets for isotopic analysis.
    Journal of chromatography. A, 2008, Jan-18, Volume: 1178, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Illicit Drugs; Isotopes; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results

2008
Direct injection LC-MS/MS method for identification and quantification of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in urine drug testing.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Jan-01, Volume: 861, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry

2008
Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA in human plasma.
    Clinical chemistry, 2008, Volume: 54, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection

2008
Development of an on-site screening system for amphetamine-type stimulant tablets with a portable attenuated total reflection Fourier transform infrared spectrometer.
    Analytica chimica acta, 2008, Feb-04, Volume: 608, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Algorithms; Amphetamines; Caffeine; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Equipment Design; Ketamine; Lactose; N-Methyl-3,4-methylenedioxyamphetamine; Software; Spectroscopy, Fourier Transform Infrared; Substance Abuse Detection; Tablets

2008
Elimination half-lives of benzoylecgonine and MDMA in an apprehended driver.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Automobile Driving; Cocaine; Forensic Toxicology; Half-Life; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection

2008
Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes.
    Archives of toxicology, 2009, Volume: 83, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adenosine Triphosphate; Animals; Cell Death; DNA Damage; Hallucinogens; Hepatocytes; Male; Methamphetamine; Mitochondria, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Phosphorylation; Rats; Rats, Inbred F344; Time Factors

2009
Simultaneous determination of amphetamine-type stimulants and cannabinoids in fingernails by gas chromatography-mass spectrometry.
    Archives of pharmacal research, 2008, Volume: 31, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamine-Related Disorders; Amphetamines; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Marijuana Abuse; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nails; Observer Variation; Reproducibility of Results; Substance Abuse Detection

2008
Development of a simultaneous liquid-liquid extraction and chiral derivatization method for stereospecific GC-MS analysis of amphetamine-type stimulants in human urine using fractional factorial design.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection

2008
Ecstasy analogues found in cacti.
    Journal of psychoactive drugs, 2008, Volume: 40, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Cactaceae; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines

2008
Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethampheta
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Oct-15, Volume: 874, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, Liquid; Deoxyepinephrine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2008
Analysis of amphetamines in urine with liquid-liquid extraction by capillary electrophoresis with simultaneous electrochemical and electrochemiluminescence detection.
    Electrophoresis, 2008, Volume: 29, Issue:19

    Topics: 2,2'-Dipyridyl; 3,4-Methylenedioxyamphetamine; Amphetamines; Electrochemical Techniques; Electrophoresis, Capillary; Female; Humans; Luminescent Measurements; Methamphetamine; Microelectrodes; N-Methyl-3,4-methylenedioxyamphetamine; Organometallic Compounds; Reproducibility of Results; Sensitivity and Specificity

2008
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
    Analytical and bioanalytical chemistry, 2009, Volume: 393, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Body Fluids; Calibration; Chromatography, High Pressure Liquid; Cocaine; Dronabinol; Humans; Illicit Drugs; Ketamine; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors

2009
Development and characterization of a novel animal model of intermittent MDMA ("Ecstasy") exposure during adolescence.
    Annals of the New York Academy of Sciences, 2008, Volume: 1139

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Animals; Anxiety; Behavior, Animal; Body Temperature; Disruptive, Impulse Control, and Conduct Disorders; Humans; Memory; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Young Adult

2008
Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Analysis of Variance; Animals; Brain; Central Nervous System Depressants; Drug Interactions; Ethanol; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Long-Evans; Time Factors

2009
Simultaneous determination of methamphetamine, 3,4-methylenedioxy-N-methylamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, N,N-dimethylamphetamine, and their metabolites in urine by liquid chromatography-electrospray ionization-tandem mass spectrometry
    Archives of pharmacal research, 2008, Volume: 31, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2008
Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxya
    Forensic science international, 2009, Jan-30, Volume: 184, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, Liquid; Deoxyepinephrine; Forensic Toxicology; Hallucinogens; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization

2009
Ecstasy analysis by monolithic materials-capillary electrochromatography.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2009, Volume: 25, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Capillary Electrochromatography; Electroosmosis; Humans; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; N-Methyl-3,4-methylenedioxyamphetamine; Osmolar Concentration; Reproducibility of Results; Tablets; Time Factors

2009
Multiple drug ingestion by ecstasy abusers in the United States.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Drug Contamination; Forensic Toxicology; Hallucinogens; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Substance Abuse Detection; Substance-Related Disorders; United States; Young Adult

2009
Direct comparison of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") disposition and metabolism in squirrel monkeys and humans.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Animals; Brain; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Haplorhini; Humans; Male; Metabolic Networks and Pathways; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Saimiri; Serotonin; Spectrometry, Mass, Electrospray Ionization; Young Adult

2009
Enantioselectivity in the methylation of the catecholic phase I metabolites of methylenedioxy designer drugs and their capability to inhibit catechol-O-methyltransferase-catalyzed dopamine 3-methylation.
    Chemical research in toxicology, 2009, Volume: 22, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Biocatalysis; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cytochrome P-450 Enzyme System; Designer Drugs; Dopamine; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Methylation; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Stereoisomerism

2009
Thermal desorption counter-flow introduction atmospheric pressure chemical ionization for direct mass spectrometry of ecstasy tablets.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Acetaminophen; Diazepam; Diphenhydramine; Mass Spectrometry; Microchemistry; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Pharmaceutical Preparations; Phenethylamines; Substance Abuse Detection; Tablets; Tandem Mass Spectrometry; Volatilization

2009
Investigations on the human hepatic cytochrome P450 isozymes involved in the metabolism of 3,4-methylenedioxy-amphetamine (MDA) and benzodioxolyl-butanamine (BDB) enantiomers.
    Toxicology letters, 2009, Oct-08, Volume: 190, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Antibodies, Monoclonal; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; In Vitro Techniques; Kinetics; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Stereoisomerism

2009
Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Disease Models, Animal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Serotonin

2009
A comparison between experimental and authentic blood/serum ratios of 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Atmospheric Pressure; Chromatography, High Pressure Liquid; Hallucinogens; Hematocrit; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Regression Analysis; Substance Abuse Detection; Tandem Mass Spectrometry

2009
Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA).
    Toxicology and applied pharmacology, 2009, Dec-15, Volume: 241, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Biotransformation; Calibration; Chromatography, Liquid; Female; Hallucinogens; Injections, Intravenous; Male; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Quality Control; Rats; Rats, Sprague-Dawley; Sex Characteristics

2009
Mice lacking multidrug resistance protein 1a show altered dopaminergic responses to methylenedioxymethamphetamine (MDMA) in striatum.
    Neurotoxicity research, 2010, Volume: 18, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin

2010
Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Female; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Young Adult

2009
Rapid and simple determination of psychotropic phenylalkylamine derivatives in human hair by gas chromatography-mass spectrometry using micro-pulverized extraction.
    Forensic science international, 2010, Mar-20, Volume: 196, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Ketamine; Limit of Detection; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection

2010
Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-15, Volume: 878, Issue:9-10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Sensitivity and Specificity

2010
Recreational drugs, 3,4-Methylenedioxymethamphetamine(MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells.
    The Journal of toxicological sciences, 2010, Volume: 35, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Depression, Chemical; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Growth Factor; Neurites; PC12 Cells; Proline; Rats

2010
Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27.
    Brain research, 2011, Jan-25, Volume: 1370

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cells, Cultured; Dendritic Spines; Hallucinogens; HSP27 Heat-Shock Proteins; Molecular Dynamics Simulation; N-Methyl-3,4-methylenedioxyamphetamine; Neocortex; Neurons; Neurotoxins; Rats; Rats, Wistar

2011
Differences in binding affinities of MDA, MDMA, MDEA, Amphetamine, Methamphetamine, and their deuterated analogues to solid-phase extraction cartridges.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Deuterium; Gas Chromatography-Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solid Phase Extraction; Substance Abuse Detection

2011
Determination of amphetamine-type stimulants, cocaine and ketamine in human hair by liquid chromatography/linear ion trap-Orbitrap hybrid mass spectrometry.
    The Analyst, 2011, Sep-07, Volume: 136, Issue:17

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Liquid; Cocaine; Hair; Humans; Illicit Drugs; Ketamine; Limit of Detection; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry

2011
Urinary excretion profiles of N-hydroxy-3,4-methylenedioxymethamphetamine in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Animals; Hydrolysis; Hydroxylation; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

2011
Simultaneous determination of HFBA-derivatized amphetamines and ketamines in urine by gas chromatography-mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Ketamine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solid Phase Extraction; Substance Abuse Detection

2011
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Binding, Competitive; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Membrane Potentials; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Oocytes; Patch-Clamp Techniques; Piperazines; Receptors, GABA-A; Time Factors; Xenopus laevis

2011
Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Central Nervous System Stimulants; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Reproducibility of Results; Substance Abuse Detection; Urinalysis

2010
Methamphetamine, amphetamine, MDMA ('ecstasy'), MDA and mCPP modulate electrical and cholinergic input in PC12 cells.
    Neurotoxicology, 2012, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Amphetamine; Animals; Calcium; Cholinergic Agents; Dose-Response Relationship, Drug; Membrane Potentials; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; PC12 Cells; Piperazines; Potassium Chloride; Rats; Serotonin Receptor Agonists

2012
Lethal serotonin syndrome after methylone and butylone ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Fatal Outcome; Female; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin Syndrome; Young Adult

2012
Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
    Reproductive toxicology (Elmsford, N.Y.), 2012, Volume: 34, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Embryo, Mammalian; Embryonic Development; Female; Hallucinogens; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Rats; Rats, Sprague-Dawley

2012
Estimation of community-wide drugs use via stereoselective profiling of sewage.
    The Science of the total environment, 2012, Apr-15, Volume: 423

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; England; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Prescription Drugs; Sewage; Stereoisomerism; Substance Abuse Detection; Substance-Related Disorders

2012
New chlorinated amphetamine-type-stimulants disinfection-by-products formed during drinking water treatment.
    Water research, 2012, Jun-15, Volume: 46, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Disinfection; Drinking Water; Halogenation; N-Methyl-3,4-methylenedioxyamphetamine; Spain; Spectrometry, Mass, Electrospray Ionization; Water Purification; Water Quality

2012
Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse.
    Neurotoxicology, 2013, Volume: 35

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Humans; Membrane Potentials; N-Methyl-3,4-methylenedioxyamphetamine; Oocytes; Patch-Clamp Techniques; Piperazines; Receptors, GABA-A; Xenopus laevis

2013
Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Biotransformation; Cell Survival; Chemical and Drug Induced Liver Injury; Deoxyepinephrine; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nonlinear Dynamics; Risk Assessment; Temperature; Time Factors

2014
Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin

2014
"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Caspase 3; Cell Death; Cell Differentiation; Cell Line; Deoxyepinephrine; Fever; Glutathione; Humans; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Temperature

2014
Glial cell response to 3,4-(+/-)-methylenedioxymethamphetamine and its metabolites.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 138, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Astrocytes; Cell Proliferation; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Male; Microglia; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sulfides

2014
Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats.
    British journal of pharmacology, 2014, Volume: 171, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular System; Consciousness; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Hallucinogens; Heart Rate; Male; Metabolic Detoxication, Phase I; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Telemetry; Time Factors

2014
Screening for illicit drugs in pooled human urine and urinated soil samples and studies on the stability of urinary excretion products of cocaine, MDMA, and MDEA in wastewater by hyphenated mass spectrometry techniques.
    Drug testing and analysis, 2017, Volume: 9, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Cocaine; Dopamine Uptake Inhibitors; Environmental Pollutants; Humans; Illicit Drugs; Limit of Detection; N-Methyl-3,4-methylenedioxyamphetamine; Soil; Substance Abuse Detection; Wastewater

2017
Enantioselective degradation of amphetamine-like environmental micropollutants (amphetamine, methamphetamine, MDMA and MDA) in urban water.
    Environmental pollution (Barking, Essex : 1987), 2016, Volume: 215

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Biodegradation, Environmental; Kinetics; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Photochemical Processes; Rivers; Sewage; Stereoisomerism; Wastewater; Water; Water Microbiology

2016
Ambient mass spectrometry for rapid diagnosis of psychoactive drugs overdose in an unstable patient.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Consciousness Disorders; Drug Overdose; Emergency Service, Hospital; Humans; Ketamine; Male; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Spectrometry, Mass, Electrospray Ionization

2018
Dibutylone (bk-DMBDB): Intoxications, Quantitative Confirmations and Metabolism in Authentic Biological Specimens.
    Journal of analytical toxicology, 2018, Sep-01, Volume: 42, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Autopsy; Biotransformation; Designer Drugs; Female; Forensic Toxicology; Humans; Liver; Male; Mass Spectrometry; Metabolomics; Microsomes, Liver; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Saliva; Substance Abuse Detection; Urinalysis; Vitreous Body; Young Adult

2018
Contaminants of Emerging Concern in Wastewaters in Barbados, West Indies.
    Bulletin of environmental contamination and toxicology, 2018, Volume: 101, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Androstenedione; Barbados; Caffeine; Chromatography, Liquid; Cocaine; Environmental Monitoring; Estrone; Ibuprofen; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2018
A Gas Chromatography-Mass Spectrometry Method for Toxicological Analysis of MDA, MDEA and MDMA in Vitreous Humor Samples from Victims of Car Accidents.
    Journal of analytical toxicology, 2018, Nov-01, Volume: 42, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Accidents, Traffic; Driving Under the Influence; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; N-Methyl-3,4-methylenedioxyamphetamine; Postmortem Changes; Reproducibility of Results; Vitreous Body

2018
[High-risk drug use: epidemiological pattern through hair testing in the forensic context].
    Revista espanola de salud publica, 2019, Nov-26, Volume: 93

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine; Cannabinoids; Cocaine; Cross-Sectional Studies; Female; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Illicit Drugs; Ketamine; Male; Methadone; Methamphetamine; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Spain; Substance Abuse Detection; Substance-Related Disorders; Young Adult

2019
A Retrospective of Prevalence of Drugs of Abuse by Hair Analysis in Shanghai using LC-MS-MS.
    Journal of analytical toxicology, 2020, Apr-02, Volume: 44, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Central Nervous System Stimulants; China; Chromatography, Liquid; Cocaine; Female; Hair; Hair Analysis; Humans; Illicit Drugs; Male; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Retrospective Studies; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2020
MDMA Intoxication in a Potential Organ Donor with Cardiac Arrest.
    Journal of analytical toxicology, 2020, Dec-12, Volume: 44, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Amphetamine; Drug Overdose; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Heart Arrest; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Tissue Donors

2020
Better living through chemistry: MDMA's prosocial mechanism as a starting point for improved therapeutics.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; N-Methyl-3,4-methylenedioxyamphetamine

2021
What is the drug of choice of young festivalgoers?
    Drug and alcohol dependence, 2020, 11-01, Volume: 216

    Topics: 3,4-Methylenedioxyamphetamine; Australia; Cocaine; Hallucinogens; Holidays; Humans; Illicit Drugs; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Substance-Related Disorders; Wastewater

2020
Application of Homogeneous Liquid-Liquid Microextraction With Switchable Hydrophilicity Solvents to the Determination of MDMA, MDA and NBOMes in Postmortem Blood Samples.
    Journal of analytical toxicology, 2022, Aug-13, Volume: 46, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Liquid Phase Microextraction; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Hydroxide; Solvents; Synthetic Drugs

2022
Development of a point-of-care test for the detection of MDMA in latent fingerprints using surface plasmon resonance and lateral flow technology.
    Drug testing and analysis, 2022, Volume: 14, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Gas Chromatography-Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Point-of-Care Testing; Substance Abuse Detection; Surface Plasmon Resonance; Technology

2022
Qualitative Screening of Amphetamine- and Ketamine-Type Abuse Drugs in Urine Employing Dual Mode Extraction Column by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS).
    Journal of analytical toxicology, 2023, Jan-24, Volume: 46, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Liquid; Ephedrine; Humans; Illicit Drugs; Ketamine; N-Methyl-3,4-methylenedioxyamphetamine; Polymethyl Methacrylate; Pseudoephedrine; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2023
Pharmacological characterization of 3,4-methylenedioxyamphetamine (MDA) analogs and two amphetamine-based compounds: N,α-DEPEA and DPIA.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022, Volume: 59

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Carrier Proteins; Dopamine; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin

2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem

2022
Quantifying the Root-to-Shoot Transfer of 4,4'-Methylenedianiline Using Pressure Chamber and Intact Plant Methods.
    Environmental toxicology and chemistry, 2023, Volume: 42, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amines; Glycine max; N-Methyl-3,4-methylenedioxyamphetamine; Plant Leaves; Plant Roots; Plants

2023
Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids.
    Journal of pharmaceutical and biomedical analysis, 2024, Jan-20, Volume: 238

    Topics: 3,4-Methylenedioxyamphetamine; Amylose; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Stereoisomerism; Tandem Mass Spectrometry

2024
The role of Ecstasy (MDMA) in managing intimacy and conflict in stable relationships.
    Culture, health & sexuality, 2018, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Conflict, Psychological; Female; Humans; Interpersonal Relations; Interviews as Topic; Love; Male; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Sexual Behavior; Substance-Related Disorders; Trust; Young Adult

2018