n-hydroxyphenacetin has been researched along with phenacetin in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (87.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayward, NK; Lavin, MF | 1 |
| Glowinski, IB; King, CM; Vaught, JB | 1 |
| Hanna, PE; Smith, TJ | 1 |
| Kitamura, S; Tatsumi, K | 1 |
| Fischbach, T; Lenk, W | 1 |
| D'Souza, CA; Davies, NW; McLean, S; Veronese, ME | 1 |
| Calder, IC; Creek, MJ; Williams, PJ | 1 |
| Hiratsuka, A; Ishidate, M; Nohmi, T; Watabe, T; Yoshikawa, K | 1 |
| Davies, NW; McLean, S; Veronese, ME | 1 |
| Glowinski, IB; Hayashi, S; Sanderson, ND; Thorgeirsson, SS | 1 |
| Alewood, P; Calder, I; Thorgeirsson, SS; Wirth, PJ | 1 |
| Dybing, E; Thorgeirsson, SS; von Bahr, C; Wirth, PJ | 1 |
| Garner, CD; King, CM; Lee, MS; Linsmaier-Bednar, EM; McGarvey, PB; Vaught, JB; Wang, CY | 1 |
| Gillette, JR; Hinson, JA; Pohl, LR | 1 |
| Kitamura, S; Sugihara, K; Tatsumi, K | 1 |
| Kitamura, S; Ohta, S; Sugihara, K; Tatsumi, K | 1 |
16 other study(ies) available for n-hydroxyphenacetin and phenacetin
| Article | Year |
|---|---|
Inhibition of DNA, RNA and protein synthesis and chromatin alteration by N-hydroxyphenacetin.
Topics: Cell Line; Cell Survival; Chromatin; DNA; DNA Damage; DNA Repair; Humans; Kidney Diseases; Phenacetin; Protein Biosynthesis; RNA | 1987 |
Metabolism of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin by guinea pig liver microsomal enzymes.
Topics: 2-Acetylaminofluorene; Acetyl-CoA Hydrolase; Animals; Binding, Competitive; Chromatography, Gel; Chromatography, High Pressure Liquid; Colorimetry; Female; Guinea Pigs; Hydroxyacetylaminofluorene; In Vitro Techniques; Microsomes, Liver; Phenacetin; RNA, Transfer; Thiolester Hydrolases | 1985 |
N-acetyltransferase multiplicity and the bioactivation of N-arylhydroxamic acids by hamster hepatic and intestinal enzymes.
Topics: 2-Acetylaminofluorene; 4-Aminobenzoic Acid; Acetylation; Acetyltransferases; Acyltransferases; Aminobenzoates; Animals; Biotransformation; Carcinogens; Chromatography, Affinity; Cricetinae; Hydroxyacetylaminofluorene; Intestines; Liver; Male; Mesocricetus; p-Aminoazobenzene; Phenacetin; RNA, Transfer | 1986 |
N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase.
Topics: 2-Acetylaminofluorene; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminobiphenyl Compounds; Animals; Cysteine; Dithiothreitol; Fluorenes; Glutathione; Hydroxamic Acids; Hydroxyacetylaminofluorene; Kinetics; Male; Phenacetin; Rabbits; Serum Albumin, Bovine | 1986 |
The metabolism of N-hydroxyphenacetin in vitro and in vivo.
Topics: Acetaminophen; Animals; Erythrocytes; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Liver; Male; Methemoglobin; Phenacetin; Rabbits; Rats | 1985 |
Formation of reactive metabolites of phenacetin in humans and rats.
Topics: Adult; Animals; Female; Humans; Male; Mass Spectrometry; Phenacetin; Rats | 1985 |
N-hydroxyphenacetinn as a precursor of 3-substituted 4-hydroxyacetanilide metabolites of phenacetin.
Topics: Acetanilides; Oxidation-Reduction; Phenacetin | 1974 |
Mechanism of species differences in N-hydroxyphenacetin mutagenicity: the role of deacetylation by rat and hamster liver microsomes.
Topics: Animals; Biotransformation; Cricetinae; Dealkylation; Male; Mesocricetus; Microsomes, Liver; Mutagenicity Tests; Mutagens; Phenacetin; Rats; Salmonella typhimurium; Species Specificity | 1984 |
Mass spectrometric determination of N-hydroxyphenacetin in urine using multiple metastable peak monitoring following thin-layer chromatography.
Topics: Chromatography, Thin Layer; Drug Stability; Humans; Mass Spectrometry; Methylation; Phenacetin | 1984 |
Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells.
Topics: 2-Acetylaminofluorene; Acyltransferases; Animals; Biotransformation; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Guinea Pigs; Hydroxyacetylaminofluorene; Kinetics; Liver Neoplasms, Experimental; Microsomes, Liver; Phenacetin; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Mutagenicity of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin and their respective deacetylated metabolites in nitroreductase deficient Salmonella TA98FR and TA100FR.
Topics: 2-Acetylaminofluorene; Animals; Ascorbic Acid; Cricetinae; Hydroxyacetylaminofluorene; Male; Mesocricetus; Microsomes, Liver; Mutagenicity Tests; Mutation; Nitro Compounds; Nitroreductases; Oxidoreductases; Phenacetin; Rats; Rats, Inbred Strains; Salmonella | 1982 |
Mechanism of N-hydroxyacetylarylamine mutagenicity in the Salmonella test system: metabolic activation of N-hydroxyphenacetin by liver and kidney fractions from rat, mouse, hamster, and man.
Topics: Acetaminophen; Animals; Ascorbic Acid; Biotransformation; Cricetinae; Humans; Kidney; Kinetics; Liver; Male; Mice; Mutagenicity Tests; Mutagens; Paraoxon; Phenacetin; Rats; Salmonella typhimurium; Species Specificity | 1980 |
Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation.
Topics: Acyltransferases; Amidohydrolases; Animals; Enzyme Activation; Microsomes, Liver; Mutagens; Nucleic Acids; Phenacetin; Rabbits; Rats; RNA, Transfer; Salmonella typhimurium; Sulfates | 1981 |
A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cricetinae; Hydroxamic Acids; Hydroxyacetylaminofluorene; Male; Mesocricetus; Microsomes, Liver; Phenacetin; Spectrophotometry; Structure-Activity Relationship | 1980 |
Reductase activity of aldehyde oxidase toward the carcinogen N-hydroxy-2-acetylaminofluorene and the related hydroxamic acids.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Aldehydes; Aminobiphenyl Compounds; Animals; Carcinogens; Guinea Pigs; Hydroxamic Acids; Hydroxyacetylaminofluorene; Liver; Mice; Oxidation-Reduction; Phenacetin; Rabbits; Rats; Vitamin K | 1994 |
Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood.
Topics: 2-Acetylaminofluorene; Animals; Blood; Carbon Monoxide; Catalase; Erythrocytes; Flavin-Adenine Dinucleotide; Hemoglobins; Hydroxamic Acids; Kinetics; Male; Models, Biological; NADP; Niacinamide; Oxygen; Phenacetin; Rabbits; Rats; Salicylamides; Time Factors | 2000 |