n-hydroxyacetaminophen has been researched along with n-acetyl-4-benzoquinoneimine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dahlin, DC; Dybing, E; Holme, JA; Nelson, SD | 1 |
| Corcoran, GB; Horning, EC; Mitchell, JR; Vaishnav, YN | 1 |
| Holme, JA; Hongslo, JK; Rannug, U; Srám, R | 1 |
1 review(s) available for n-hydroxyacetaminophen and n-acetyl-4-benzoquinoneimine
| Article | Year |
|---|---|
International Commission for Protection against Environmental Mutagens and Carcinogens. An evaluation of the genetic toxicity of paracetamol.
Topics: Acetaminophen; Acetates; Acetic Acid; Adult; Aminophenols; Animals; Bacteria; Benzoquinones; Biotransformation; Cell Line; Child; Chromosomes; DNA Damage; DNA Repair; DNA Replication; Female; Humans; Imines; Mutagenicity Tests; Plants; Rats; Rats, Sprague-Dawley; Ribonucleotide Reductases; Rodentia | 1995 |
2 other study(ies) available for n-hydroxyacetaminophen and n-acetyl-4-benzoquinoneimine
| Article | Year |
|---|---|
Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol.
Topics: Acetaminophen; Animals; Benzoquinones; Dose-Response Relationship, Drug; Glutathione; Imines; In Vitro Techniques; Lipid Peroxides; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine.
Topics: Acetaminophen; Animals; Ascorbic Acid; Benzoquinones; Cysteine; Imines; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats | 1980 |