n-hydroxy-4-phosphonobutanamide has been researched along with fosmidomycin in 4 studies
*fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source [MeSH]
*fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source [MeSH]
| Studies (n-hydroxy-4-phosphonobutanamide) | Trials (n-hydroxy-4-phosphonobutanamide) | Recent Studies (post-2010) (n-hydroxy-4-phosphonobutanamide) | Studies (fosmidomycin) | Trials (fosmidomycin) | Recent Studies (post-2010) (fosmidomycin) |
|---|---|---|---|---|---|
| 6 | 0 | 3 | 243 | 10 | 116 |
| Protein | Taxonomy | n-hydroxy-4-phosphonobutanamide (IC50) | fosmidomycin (IC50) |
|---|---|---|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycolicibacterium smegmatis MC2 155 | 0.295 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | 0.0334 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis H37Rv | 0.165 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic | Arabidopsis thaliana (thale cress) | 0.1 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli | 0.438 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heidler, P; Klebe, G; Kurz, T; Silber, K | 1 |
| Grosdemange-Billiard, C; Ponaire, S; Rohmer, M; Tritsch, D; Zinglé, C | 1 |
| Esque, J; Grosdemange-Billiard, C; Hemmerlin, A; Krebs, F; Munier, M; Rohmer, M; Stote, RH; Tritsch, D | 1 |
| Bach, TJ; Grosdemange-Billiard, C; Hemmerlin, A; Kuntz, L; Rohmer, M; Tritsch, D; Willem, A | 1 |
4 other study(ies) available for n-hydroxy-4-phosphonobutanamide and fosmidomycin
| Article | Year |
|---|---|
AFMoC enhances predictivity of 3D QSAR: a case study with DOXP-reductoisomerase.
Topics: Aldose-Ketose Isomerases; Antimalarials; Binding Sites; Crystallography, X-Ray; Fosfomycin; Ligands; Models, Molecular; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship | 2005 |
Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents.
Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Enzyme Inhibitors; Fosfomycin; Hydrophobic and Hydrophilic Interactions; Kinetics; Microbial Viability; Multienzyme Complexes; Mycobacterium smegmatis; Organophosphonates; Oxazines; Oxidoreductases; Prodrugs; Xanthenes | 2012 |
Synthesis and biological evaluation of phosphate isosters of fosmidomycin and analogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases.
Topics: Aldose-Ketose Isomerases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Fosfomycin; Molecular Structure; Mycobacterium smegmatis; Phosphates; Structure-Activity Relationship | 2017 |
Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase.
Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Antimalarials; Butyrates; Drug Design; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fosfomycin; Hydroxamic Acids; Microbial Sensitivity Tests; Multienzyme Complexes; NADP; Organophosphonates; Oxidoreductases; Terpenes | 2005 |