Page last updated: 2024-09-03

n-hydroxy-4-phosphonobutanamide and 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid

n-hydroxy-4-phosphonobutanamide has been researched along with 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid in 3 studies

Compound Research Comparison

Studies
(n-hydroxy-4-phosphonobutanamide)
Trials
(n-hydroxy-4-phosphonobutanamide)
Recent Studies (post-2010)
(n-hydroxy-4-phosphonobutanamide)
Studies
(3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid)
Trials
(3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid)
Recent Studies (post-2010) (3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid)
60350028

Protein Interaction Comparison

ProteinTaxonomyn-hydroxy-4-phosphonobutanamide (IC50)3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid (IC50)
1-deoxy-D-xylulose 5-phosphate reductoisomeraseMycolicibacterium smegmatis MC2 1550.32
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli K-120.0365
1-deoxy-D-xylulose 5-phosphate reductoisomeraseMycobacterium tuberculosis H37Rv1.275

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heidler, P; Klebe, G; Kurz, T; Silber, K1
Grosdemange-Billiard, C; Ponaire, S; Rohmer, M; Tritsch, D; Zinglé, C1
Esque, J; Grosdemange-Billiard, C; Hemmerlin, A; Krebs, F; Munier, M; Rohmer, M; Stote, RH; Tritsch, D1

Other Studies

3 other study(ies) available for n-hydroxy-4-phosphonobutanamide and 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid

ArticleYear
AFMoC enhances predictivity of 3D QSAR: a case study with DOXP-reductoisomerase.
    Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

    Topics: Aldose-Ketose Isomerases; Antimalarials; Binding Sites; Crystallography, X-Ray; Fosfomycin; Ligands; Models, Molecular; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship

2005
Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Enzyme Inhibitors; Fosfomycin; Hydrophobic and Hydrophilic Interactions; Kinetics; Microbial Viability; Multienzyme Complexes; Mycobacterium smegmatis; Organophosphonates; Oxazines; Oxidoreductases; Prodrugs; Xanthenes

2012
Synthesis and biological evaluation of phosphate isosters of fosmidomycin and analogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases.
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Aldose-Ketose Isomerases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Fosfomycin; Molecular Structure; Mycobacterium smegmatis; Phosphates; Structure-Activity Relationship

2017