Page last updated: 2024-09-03

n-formylmethionyl-leucyl-phenylalanyl-lysine and n-formylmethionine leucyl-phenylalanine

n-formylmethionyl-leucyl-phenylalanyl-lysine has been researched along with n-formylmethionine leucyl-phenylalanine in 32 studies

Compound Research Comparison

Studies
(n-formylmethionyl-leucyl-phenylalanyl-lysine)
Trials
(n-formylmethionyl-leucyl-phenylalanyl-lysine)
Recent Studies (post-2010)
(n-formylmethionyl-leucyl-phenylalanyl-lysine)
Studies
(n-formylmethionine leucyl-phenylalanine)
Trials
(n-formylmethionine leucyl-phenylalanine)
Recent Studies (post-2010) (n-formylmethionine leucyl-phenylalanine)
36056,71653356

Protein Interaction Comparison

ProteinTaxonomyn-formylmethionyl-leucyl-phenylalanyl-lysine (IC50)n-formylmethionine leucyl-phenylalanine (IC50)
fMet-Leu-Phe receptorHomo sapiens (human)0.02

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's11 (34.38)18.2507
2000's9 (28.13)29.6817
2010's4 (12.50)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Bucknall, RC; Edwards, SW; Ledson, MJ1
Grdisa, M; Vitale, L1
Bender, JG; Chenoweth, DE; Simpson, SJ; Van Epps, DE1
Henderson, LE; Leonard, EJ; Rot, A; Sowder, R1
Allen, RA; Erickson, RW; Jesaitis, AJ1
Mason, MJ; Van Epps, DE1
Falloon, J; Friedman, MM; Gallin, JI; Nath, J; Ohno, Y; Seligmann, BE1
Baehner, RL; Haak, RA; Lafuze, JE; Weisman, SJ1
Gutierrez, L; Maez, D; Saland, LC; Samora, A; Van Epps, DE1
Chenoweth, DE; Lewis, SL; Van Epps, DE1
Aksamit, RR; Cunningham, RE; Harvath, L1
Bailly, S; Chollet-Martin, S; Elbim, C; Gougerot-Pocidalo, MA; Hakim, J1
Johnson, R; Simpson, SJ; Van Epps, DE1
Barrett, JA; Boerman, OC; Corstens, FH; Edwards, DS; Oyen, WJ; van de Ven, MT; van der Laken, CJ; van der Meer, JW1
Babich, JW; Barrow, SA; Fischman, AJ; Graham, W; Tompkins, RG1
Vallabhajosula, S1
Boulay, F; Christophe, T; Milcent, MD; Rabiet, MJ; Tardif, M1
Carter, EA; Fernandez-Del Castillo, C; Fischman, AJ; Hartwig, W; Jimenez, RE; Warshaw, AL; Werner, J1
Bennett, TA; Lynam, E; Neldon, D; Prossnitz, E; Sklar, LA; Vilven, J1
Gamaley, IA; Ischenko, AM; Kirpichnikova, KM; Klyubin, IV; Zhakhov, AV1
Adorjáni, E; Bielik, H; Csekö, C; Fürész, J; Lakatos, S; Németh, K1
Drayer, AL; Fuhler, GM; Hooijenga, F; Vellenga, E1
Bailleul, F; Brunet, C; Daels-Rakotoarison, DA; Dine, T; Gressier, B; Kouakou, G; Luyckx, M; Trotin, F1
Graessler, J; Kopprasch, S; Pietzsch, J1
Heuertz, RM; Potempa, LA; Schneider, GP; Webster, RO1
Bootman, MD; Conway, SJ; Hogg, N; McNeill, E; Roderick, HL1
Dratz, EA; Gripentrog, JM; Jesaitis, AJ; Lord, CI; Miettinen, HM; Mumey, B; Riesselman, M; Stie, J; Taylor, RM1
Chapple, IL; Dias, IH; Dunston, CR; Griffiths, HR; Matthews, JB; Wright, HJ1
Anderson, R; Cockeran, R; Feldman, C; Mutepe, ND; Richards, GA; Steel, HC; Stivaktas, PI; Theron, AJ; Tintinger, GR1
Berton, G; Campa, CC; Fumagalli, L; Germena, G; Hirsch, E; Lowell, CA1
Caltabiano, G; He, HQ; Pardo, L; Troksa, EL; Ye, RD1
Abrahão, O; Rogério, AP; Schmitz Nunes, V1

Other Studies

32 other study(ies) available for n-formylmethionyl-leucyl-phenylalanyl-lysine and n-formylmethionine leucyl-phenylalanine

ArticleYear
Inhibition of neutrophil oxidant secretion by D-penicillamine: scavenging of H2O2 and HOCl.
    Annals of the rheumatic diseases, 1992, Volume: 51, Issue:3

    Topics: Humans; Hydrogen Peroxide; Hypochlorous Acid; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Penicillamine

1992
The fate of human polymorphonuclear leukocyte aminopeptidases upon cell stimulation with phagocytic and chemical stimuli.
    The International journal of biochemistry, 1991, Volume: 23, Issue:9

    Topics: Aminopeptidases; Cell Degranulation; Cell Division; Humans; Isoelectric Focusing; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Tetradecanoylphorbol Acetate; Zymosan

1991
Relationship of chemotactic receptors for formyl peptide and C5a to CR1, CR3, and Fc receptors on human neutrophils.
    Journal of leukocyte biology, 1990, Volume: 47, Issue:6

    Topics: Antibodies, Monoclonal; Complement C3b; Complement C5a; Flow Cytometry; Fluorescent Dyes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Complement; Receptors, Complement 3b; Receptors, Fc; Receptors, Formyl Peptide; Receptors, Immunologic

1990
Staphylococcus aureus tetrapeptide with high chemotactic potency and efficacy for human leukocytes.
    Journal of leukocyte biology, 1989, Volume: 45, Issue:2

    Topics: Amino Acids; Binding, Competitive; Chemotactic Factors; Chemotaxis, Leukocyte; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Receptors, Formyl Peptide; Receptors, Immunologic; Staphylococcus aureus; Thiocyanates

1989
Identification of a human neutrophil protein of Mr 24 000 that binds N-formyl peptides: co-sedimentation with specific granules.
    Biochimica et biophysica acta, 1989, Apr-25, Volume: 991, Issue:1

    Topics: Affinity Labels; Amino Acid Sequence; Azides; Binding, Competitive; Cations, Divalent; Cell Membrane; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Humans; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peptide Hydrolases; Receptors, Formyl Peptide; Receptors, Immunologic; Subcellular Fractions

1989
In vivo neutrophil emigration in response to interleukin-1 and tumor necrosis factor-alpha.
    Journal of leukocyte biology, 1989, Volume: 45, Issue:1

    Topics: Animals; Cell Movement; Complement C5; Complement C5a; Interleukin-1; Mice; Mice, Inbred C3H; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tumor Necrosis Factor-alpha

1989
Separation and function of neutrophil karyogranuloplasts and comparison with cytoplasts and intact cells.
    Inflammation, 1987, Volume: 11, Issue:3

    Topics: Cell Aggregation; Cell Movement; Cell Nucleus; Cell Separation; Cytoplasmic Granules; Humans; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organoids; Osmolar Concentration; Superoxides; Tetradecanoylphorbol Acetate

1987
Effect of vitamin E on FMLP-induced activation of rabbit polymorphonuclear leukocytes.
    Inflammation, 1987, Volume: 11, Issue:3

    Topics: Animals; Cell Adhesion; Cell Separation; Endothelium, Vascular; Male; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Receptors, Cell Surface; Vitamin E

1987
Acute infusion of chemotactic or enkephalin-analog peptides into rat cerebral ventricles: scanning and transmission electron microscopy of leukocyte immigration in vivo.
    Journal of neuroimmunology, 1988, Volume: 18, Issue:3

    Topics: Animals; Cerebral Ventricles; Chemotactic Factors; Chemotaxis, Leukocyte; Enkephalins; Hypothalamus, Middle; Injections; Male; Microscopy, Electron; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Inbred Strains

1988
C5a receptor modulation on neutrophils and monocytes from chronic hemodialysis and peritoneal dialysis patients.
    Clinical nephrology, 1986, Volume: 26, Issue:1

    Topics: Complement C3; Complement C3a; Complement C5; Complement C5a; Flow Cytometry; Humans; Immunoglobulin G; Kidney Failure, Chronic; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Dialysis, Continuous Ambulatory; Receptors, Complement; Renal Dialysis

1986
Assay for chemoattractant binding.
    Methods in molecular biology (Clifton, N.J.), 1994, Volume: 34

    Topics: Amino Acid Sequence; Chemotactic Factors; Flow Cytometry; Fluoresceins; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding

1994
Differential priming effects of proinflammatory cytokines on human neutrophil oxidative burst in response to bacterial N-formyl peptides.
    Infection and immunity, 1994, Volume: 62, Issue:6

    Topics: Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen Peroxide; Interleukins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst

1994
Relationship of C5a receptor modulation to the functional responsiveness of human polymorphonuclear leukocytes to C5a.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Jan-01, Volume: 150, Issue:1

    Topics: Complement C5a; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic

1993
Technetium-99m-labeled chemotactic peptides in acute infection and sterile inflammation.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: Abscess; Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Escherichia coli Infections; Female; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Organotechnetium Compounds; Rabbits; Radionuclide Imaging; Soft Tissue Infections; Staphylococcal Infections; Technetium; Zymosan

1997
Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: Animals; Chemotactic Factors; Erythrocytes; Escherichia coli Infections; Humans; Immunoglobulin G; Indium Radioisotopes; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Organotechnetium Compounds; Pentetic Acid; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Soft Tissue Infections; Technetium; Time Factors; Tissue Distribution

1997
Technetium-99m-labeled chemotactic peptides: specific for imaging infection?
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: Animals; Chemotactic Factors; Escherichia coli Infections; Isotope Labeling; N-Formylmethionine Leucyl-Phenylalanine; Organotechnetium Compounds; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Soft Tissue Infections; Technetium; Tissue Distribution

1997
Isolation and characterization of a variant HL60 cell line defective in the activation of the NADPH oxidase by phorbol myristate acetate.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Dec-15, Volume: 161, Issue:12

    Topics: Androstadienes; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; HL-60 Cells; Humans; Isoenzymes; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella; Wortmannin

1998
Chemotactic peptide uptake in acute pancreatitis: correlation with tissue accumulation of leukocytes.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:2

    Topics: Animals; Ceruletide; Disease Models, Animal; Edema; Histocytochemistry; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nicotinic Acids; Oligopeptides; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Technetium Compounds

1999
Solubilization and display of G protein-coupled receptors on beads for real-time fluorescence and flow cytometric analysis.
    BioTechniques, 2000, Volume: 28, Issue:5

    Topics: Chemotactic Factors; Computer Systems; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Expression; GTP-Binding Proteins; Histidine; Humans; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; Nitrilotriacetic Acid; Organometallic Compounds; Protein Binding; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Silicon Dioxide; Solubility; Spectrometry, Fluorescence; Transfection; U937 Cells

2000
The role of reactive oxygen species in membrane potential changes in macrophages and astrocytes.
    Membrane & cell biology, 2000, Volume: 13, Issue:4

    Topics: Anaphylatoxins; Animals; Astrocytes; Catalase; Cell Membrane; Fluorescent Dyes; Glioblastoma; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured

2000
Azurophil granules are heterogeneous with respect to mobilization induced by different concentrations of fMLP.
    Haematologia, 2001, Volume: 31, Issue:3

    Topics: Calcium; Cell Degranulation; Cytoplasmic Granules; Dose-Response Relationship, Drug; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase

2001
Reduced expression of flavocytochrome b558, a component of the NADPH oxidase complex, in neutrophils from patients with myelodysplasia.
    Experimental hematology, 2003, Volume: 31, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Cytochrome b Group; Female; Gene Expression Regulation, Enzymologic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Middle Aged; Myelodysplastic Syndromes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Reactive Oxygen Species

2003
Effects of a caffeine-free Cola nitida nuts extract on elastase/alpha-1-proteinase inhibitor balance.
    Journal of ethnopharmacology, 2003, Volume: 89, Issue:1

    Topics: alpha 1-Antitrypsin; Caffeine; Calcimycin; Cell Survival; Cola; Enzyme Activators; Free Radical Scavengers; Humans; Hydrogen Peroxide; In Vitro Techniques; Ionophores; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuts; Plant Extracts; Tetradecanoylphorbol Acetate; Type C Phospholipases

2003
The protective effects of HDL and its constituents against neutrophil respiratory burst activation by hypochlorite-oxidized LDL.
    Molecular and cellular biochemistry, 2004, Volume: 258, Issue:1-2

    Topics: Apolipoprotein A-I; Chemotactic Factors; Humans; Hypochlorous Acid; Lipoproteins, HDL; Lipoproteins, LDL; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Oxidation-Reduction; Protective Agents; Reactive Oxygen Species; Respiratory Burst; Zymosan

2004
Native and modified C-reactive protein bind different receptors on human neutrophils.
    The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:2

    Topics: Animals; C-Reactive Protein; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Protein Structure, Quaternary; Rabbits; Receptors, IgG

2005
Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils.
    Cell calcium, 2007, Volume: 41, Issue:2

    Topics: Animals; Calcium Signaling; Calgranulin B; Cells, Cultured; Chemokine CXCL2; Chemokines; Chemotactic Factors; Diglycerides; Estrenes; Homeostasis; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Knockout; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrrolidinones; Type C Phospholipases

2007
C-terminal tail phosphorylation of N-formyl peptide receptor: differential recognition of two neutrophil chemoattractant receptors by monoclonal antibodies NFPR1 and NFPR2.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Aug-15, Volume: 179, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Chemotaxis; CHO Cells; Chromatography, Affinity; Cricetinae; Cricetulus; Epitope Mapping; Epitopes; Fibroblasts; Gene Expression; Humans; Lactoferrin; Lysophospholipids; Mice; Models, Immunological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, Formyl Peptide; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera

2007
Activation of the neutrophil respiratory burst by plasma from periodontitis patients is mediated by pro-inflammatory cytokines.
    Journal of clinical periodontology, 2011, Volume: 38, Issue:1

    Topics: Adult; Case-Control Studies; Chemotactic Factors; Chronic Periodontitis; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation Mediators; Interferon-alpha; Interleukin-8; Luminescence; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Plasma; Recombinant Proteins; Respiratory Burst; Statistics, Nonparametric; Stimulation, Chemical

2011
Calcium-dependent potentiation of the pro-inflammatory functions of human neutrophils by tigecycline in vitro.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:1

    Topics: Adult; Calcium; Cells, Cultured; Cytosol; Human Experimentation; Humans; Immunologic Factors; Minocycline; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tigecycline

2012
Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-01, Volume: 190, Issue:7

    Topics: Animals; Cell Adhesion; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Isoenzymes; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-vav; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; src-Family Kinases; Tumor Necrosis Factors

2013
Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands.
    The Journal of biological chemistry, 2014, Jan-24, Volume: 289, Issue:4

    Topics: Amino Acid Substitution; Humans; Ligands; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; Receptors, CXCR4; Receptors, Formyl Peptide; Receptors, Lipoxin; Structural Homology, Protein; Structure-Activity Relationship

2014
Insights into the Activation Mechanism of the ALX/FPR2 Receptor.
    The journal of physical chemistry letters, 2020, Nov-05, Volume: 11, Issue:21

    Topics: Amino Acid Sequence; Anti-Inflammatory Agents; Cytoplasm; Docosahexaenoic Acids; Glucocorticoids; Humans; Molecular Dynamics Simulation; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction; Static Electricity

2020