n-formylmethionine leucyl-phenylalanine and pentoxifylline

n-formylmethionine leucyl-phenylalanine has been researched along with pentoxifylline in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.81)18.7374
1990's28 (75.68)18.2507
2000's4 (10.81)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carper, HT; Mandell, GL; Sullivan, GW1
Crouch, SP; Fletcher, J1
Bardenheuer, H; Madel, C; Peter, K; Pöch, G; Thiel, M1
Schmid-Schönbein, GW; Wong, PM1
Hiraoka, N; Kitagawa, K; Mori, T; Murata, A; Nishijima, J; Ogawa, M; Oka, Y; Yasuda, T1
Cohen, HJ; Crawford, J; Currie, MS; Jones, A; Padmanabhan, J; Rao, KM1
Carper, HT; Hewlett, EL; Hylton, JB; Linden, J; Mandell, GL; Sullivan, GW1
Banks, SM; Buescher, ES; McIlheran, SM; Vadhan-Raj, S1
Belloc, F; Boisseau, MR; Freyburger, G2
Carper, HT; Mandell, GL; Novick, WJ; Sullivan, GW1
Cohen, HJ; Crawford, J; Currie, MS; Rao, KM1
Augustine, NH; Hill, HR; Morris, E; Newton, JA; Sacchi, F; Shigeoka, AO1
Kreutzer, DL; Sheetz, MP; Wang, WP1
Hand, DL; Hand, WL1
Komiyama, A; Molski, TF; Sha'afi, RI; Yasui, K1
Hansen, PR; Stawski, G1
Bodlaj, R; Glaubitt, SI; Hübner, C; Krombach, F; Lehr, HA; Messmer, K; Münzing, S; Seiffge, D; von Andrian, UH1
Edwards, MJ; Knott, AW; Miller, FN; Nakagawa, K1
Duncker, HP; Koch, T; Möschet, B; Neuhof, H; Schönharting, M; Stein, A; van Ackern, K1
Addison, IE; Carver, JE; Johnson, BV; Khwaja, A; Linch, DC; Pizzey, AR; Roberts, PJ; Yong, KL1
Hammerle, AF; Mayer, N; Micksche, M; Oismüller, C; Steltzer, H1
Antonaci, S; Jirillo, E; Piazzolla, G; Polignano, A; Serrone, M; Tortorella, C1
Paradowski, PT; Pietruszyński, R; Zeman, K1
Arakawa, S; Fujisawa, M; Kamidono, S; Kanzaki, M; Okada, H; Tatsumi, N1
Andrioli, G; Bambara, LM; Bellavite, P; Biasi, D; Bonazzi, ML; Caramaschi, P; Carletto, A; Lussignoli, S1
Clark, SC; Dark, JH; Kirby, JA1
Dunzendorfer, S; Kähler, CM; Reinisch, N; Schratzberger, P; Wiedermann, CJ1
de Koster, BM; Elferink, JG; Huizinga, TW1
Bursten, SL; Chaney, RB; Guidot, DM; Hybertson, BM; Repine, AJ; Repine, JE; Rice, GC; Singer, JW1
Atger, V; Cogny, A; Lenoble, M; Moatti, N; Paul, JL; Surbled, B1
Baj, Z; Czekalska, R; Janiszewska-Drobinska, B; Kosmider, M; Kowalski, J; Pasnik, J; Zeman, K1
Altfelder, F; Craciun, E; Linderkamp, O; Poeschl, JM; Ruef, P; Simon, C1
Coimbra, R; Hoyt, DB; Lall, RN; Lane, T; Loomis, W; Melbostad, H1
Coimbra, R; Deree, J; Grant, M; Hoyt, DB; Lall, R; Melbostad, H1
Coimbra, R; Deree, J; Loomis, WH; Melbostad, H; Putnam, JG1
Bansal, V; Coimbra, R; Costantini, TW; Deree, J; Loomis, WH; Peterson, CY; Putnam, JG; Woon, T1

Trials

2 trial(s) available for n-formylmethionine leucyl-phenylalanine and pentoxifylline

ArticleYear
In vivo modulation of human neutrophil function by pentoxifylline in patients with septic syndrome.
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:3

    Topics: Adult; Humans; Infusions, Intravenous; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Respiratory Burst; Sepsis; Tetradecanoylphorbol Acetate

1995
Pentoxifylline decreases neutrophil respiratory bursts in patients with stable angina.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:2

    Topics: Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Depression, Chemical; Female; Humans; In Vitro Techniques; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999

Other Studies

35 other study(ies) available for n-formylmethionine leucyl-phenylalanine and pentoxifylline

ArticleYear
Pentoxifylline modulates activation of human neutrophils by amphotericin B in vitro.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:2

    Topics: Amphotericin B; Antioxidants; Gene Expression Regulation; Hemolysis; Humans; In Vitro Techniques; Luminescent Measurements; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Pentoxifylline; Superoxides; Xanthines

1992
Effect of ingested pentoxifylline on neutrophil superoxide anion production.
    Infection and immunity, 1992, Volume: 60, Issue:11

    Topics: Administration, Oral; Antigens, CD; CD18 Antigens; Cell Adhesion Molecules; Humans; Lactoferrin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Superoxides; Xanthines; Zymosan

1992
Pentoxifylline does not act via adenosine receptors in the inhibition of the superoxide anion production of human polymorphonuclear leukocytes.
    Biochemical and biophysical research communications, 1991, Oct-15, Volume: 180, Issue:1

    Topics: Adenosine; Dose-Response Relationship, Drug; Drug Combinations; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Purinergic Antagonists; Receptors, Purinergic; Superoxides; Theophylline

1991
Attenuation of spontaneous pseudopod formation in human neutrophils by pentoxifylline.
    Cell biophysics, 1991, Volume: 18, Issue:3

    Topics: Actins; Adult; Complement C5a; Cytoplasm; Dose-Response Relationship, Drug; Endotoxins; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pseudopodia; Receptors, Purinergic; Theophylline; Time Factors

1991
Inhibitory effect of pentoxifylline and prostaglandin E1 on the release of neutrophil elastase from FMLP-stimulated neutrophils.
    Journal of medicine, 1991, Volume: 22, Issue:6

    Topics: Alprostadil; Humans; In Vitro Techniques; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Pentoxifylline

1991
Stimulus-specific effects of pentoxifylline on neutrophil CR3 expression, degranulation, and superoxide production.
    Journal of leukocyte biology, 1990, Volume: 47, Issue:3

    Topics: Adenosine; Cell Degranulation; Cytoskeleton; Glucans; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Receptors, Complement; Receptors, Complement 3b; Superoxides; Tetradecanoylphorbol Acetate; Theobromine

1990
Adenosine and related compounds counteract tumor necrosis factor-alpha inhibition of neutrophil migration: implication of a novel cyclic AMP-independent action on the cell surface.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Sep-01, Volume: 145, Issue:5

    Topics: Actins; Adenosine; Adenosine Deaminase; Cell Movement; Chemotaxis, Leukocyte; Cyclic AMP; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Pentoxifylline; Receptors, Purinergic; Recombinant Proteins; Tumor Necrosis Factor-alpha; Xanthines

1990
Alteration of the functional effects of granulocyte-macrophage colony-stimulating factor on polymorphonuclear leukocytes by membrane-fluidizing agents.
    Infection and immunity, 1990, Volume: 58, Issue:9

    Topics: 1-Butanol; Butanols; Chemotaxis, Leukocyte; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; In Vitro Techniques; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Sarcoma; Superoxides; Theobromine

1990
Flow cytometry analysis of human neutrophils labeled with rhodamine phalloidin: effect of pentoxifylline.
    Biorheology, 1990, Volume: 27, Issue:3-4

    Topics: Actins; Flow Cytometry; Fluorescent Dyes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Stimulation, Chemical

1990
Pentoxifylline inhibits actin polymerization in human neutrophils after stimulation by chemoattractant factor.
    Agents and actions, 1990, Volume: 31, Issue:1-2

    Topics: Actins; Chemotactic Factors; Chemotaxis, Leukocyte; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Humans; In Vitro Techniques; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Octoxynol; Pentoxifylline; Phalloidine; Polyethylene Glycols; Rhodamines; Stimulation, Chemical

1990
Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline.
    Infection and immunity, 1988, Volume: 56, Issue:7

    Topics: Anti-Inflammatory Agents; Calcium; Cell Adhesion; Cell Movement; Culture Media; Cytoplasmic Granules; Cytosol; Free Radicals; Humans; Interleukin-1; Leukocytes, Mononuclear; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Receptors, Formyl Peptide; Receptors, Immunologic; Recombinant Proteins; Superoxides; Theobromine; Tumor Necrosis Factor-alpha

1988
Actin depolymerization and inhibition of capping induced by pentoxifylline in human lymphocytes and neutrophils.
    Journal of cellular physiology, 1988, Volume: 137, Issue:3

    Topics: Actins; Bucladesine; Humans; Immunologic Capping; Lymphocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pertussis Toxin; Polymers; Theobromine; Virulence Factors, Bordetella

1988
Correction of a developmental defect in neutrophil activation and movement.
    The American journal of pathology, 1987, Volume: 128, Issue:2

    Topics: Adenosine Triphosphate; Anesthetics, Local; Cell Movement; Colchicine; Concanavalin A; Cyclic AMP; Fetal Blood; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Mitogen

1987
Polyphosphoinositides as regulators of membrane skeletal stability.
    Kroc Foundation series, 1984, Volume: 16

    Topics: Animals; Chemotaxis, Leukocyte; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphatidylinositols; Rabbits

1984
Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cells.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:7

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Cells, Cultured; Clindamycin; Drug Interactions; Erythromycin; Humans; Macrolides; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phagocytosis; Respiratory Burst; Roxithromycin; Superoxides

1995
Pentoxifylline and CD14 antibody additively inhibit priming of polymorphonuclear leukocytes for enhanced release of superoxide by lipopolysaccharide: possible mechanism of these actions.
    Infection and immunity, 1994, Volume: 62, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Enzyme Activation; GTP-Binding Proteins; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phospholipase D; Superoxides

1994
Neutrophil mediated damage to isolated myocytes after anoxia and reoxygenation.
    Cardiovascular research, 1994, Volume: 28, Issue:4

    Topics: alpha-Macroglobulins; Animals; Antibodies, Monoclonal; Antigens, CD; Arginine; Catalase; CD18 Antigens; Cells, Cultured; Deferoxamine; Histidine; Interleukin-1; L-Lactate Dehydrogenase; Myocardial Reperfusion Injury; Myocardium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Proteins; Rats; Receptors, Leukocyte-Adhesion; Serpins; Superoxide Dismutase

1994
In vitro effects of oxidized low density lipoprotein on CD11b/CD18 and L-selectin presentation on neutrophils and monocytes with relevance for the in vivo situation.
    The American journal of pathology, 1995, Volume: 146, Issue:1

    Topics: 1-Butanol; Adult; Animals; Butanols; CD18 Antigens; Cell Adhesion Molecules; Cells, Cultured; Cricetinae; Female; Flow Cytometry; Fluorescence Polarization; Humans; L-Selectin; Lipoproteins, LDL; Macrophage-1 Antigen; Male; Mesocricetus; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1995
Pentoxifylline inhibits FMLP-induced macromolecular leakage.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 2

    Topics: Animals; Bucladesine; Capillary Permeability; Cell Adhesion; Leukocytes; Macromolecular Substances; Male; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Pentoxifylline; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine

1995
Influence of a pentoxifylline-analogue on the granulocyte-mediated pulmonary mediator release and vascular reaction.
    Circulatory shock, 1993, Volume: 40, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Female; Histamine Release; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pulmonary Artery; Rabbits; Tetradecanoylphorbol Acetate; Thromboxane B2; Vascular Resistance

1993
Pentoxifylline at clinically achievable levels inhibits FMLP-induced neutrophil responses, but not priming, upregulation of cell-adhesion molecules, or migration induced by GM-CSF.
    European journal of haematology, 1993, Volume: 50, Issue:1

    Topics: Antigens, CD; CD11 Antigens; Cell Adhesion Molecules; Chemotaxis, Leukocyte; Cyclic AMP; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Sepharose; Tumor Necrosis Factor-alpha

1993
Lipopolysaccharide-, granulocyte-monocyte colony stimulating factor and pentoxifylline-mediated effects on formyl-methionyl-leucine-phenylalanine-stimulated neutrophil respiratory burst in the elderly.
    Microbios, 1996, Volume: 85, Issue:344

    Topics: Aged; Aged, 80 and over; Aging; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lipopolysaccharides; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Superoxides

1996
Pentoxifylline inhibits tumor necrosis factor alpha-induced priming of human neutrophils.
    Immunology letters, 1996, Volume: 53, Issue:2-3

    Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Pentoxifylline; Phosphodiesterase Inhibitors; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1996
Formation of reactive oxygen species by spermatozoa from asthenospermic patients: response to treatment with pentoxifylline.
    The Journal of urology, 1997, Volume: 157, Issue:6

    Topics: Fertilization; Humans; Infertility, Male; Male; N-Formylmethionine Leucyl-Phenylalanine; Pentoxifylline; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate

1997
Studies of skin-window exudate human neutrophils: increased resistance to pentoxifylline of the respiratory burst in primed cells.
    Inflammation, 1997, Volume: 21, Issue:2

    Topics: Cyclic AMP; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Skin Window Technique; Superoxides; Zymosan

1997
An assay of neutrophil adhesion to fibronectin and its attenuation by pentoxifylline and nitric oxide.
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: Cell Adhesion; Fibronectins; Humans; In Vitro Techniques; Lipopolysaccharides; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentoxifylline

1997
Augmentation of tumor necrosis factor-alpha-induced priming of fMet-Leu-Phe-stimulated neutrophils by pentoxifylline.
    Immunology letters, 1997, Volume: 58, Issue:2

    Topics: Chemotaxis, Leukocyte; Cytoplasmic Granules; Drug Synergism; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Superoxides; Tumor Necrosis Factor-alpha

1997
The effect of pentoxifylline on human neutrophil migration: a possible role for cyclic nucleotides.
    Biochemical pharmacology, 1997, Aug-15, Volume: 54, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Calcium; Cell Movement; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline

1997
Modulating phosphatidic acid metabolism decreases oxidative injury in rat lungs.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Chemotaxis, Leukocyte; Humans; Hydrogen Peroxide; Interleukin-8; Linoleic Acid; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Organ Size; Oxidative Stress; Pentoxifylline; Perfusion; Phosphatidic Acids; Rats; Rats, Sprague-Dawley; Superoxides

1997
Oxidative modification of high-density lipoprotein 3 induced by human polymorphonuclear neutrophils. Protective effect of pentoxifylline.
    European journal of biochemistry, 1999, Volume: 259, Issue:1-2

    Topics: Antioxidants; Apolipoprotein A-I; Dose-Response Relationship, Drug; Humans; Lipoproteins, HDL; Lipoproteins, HDL3; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Pentoxifylline; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Vitamin E

1999
Effect of activators and the phosphodiesterase inhibitors pentoxifylline and enoximone on the deformability of neutrophils in neonates and adults.
    Acta paediatrica (Oslo, Norway : 1992), 2004, Volume: 93, Issue:10

    Topics: Adult; Enoximone; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Infant, Newborn; Interleukin-8; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Tumor Necrosis Factor-alpha

2004
Phosphodiesterase inhibition attenuates stored blood-induced neutrophil activation: a novel adjunct to blood transfusion.
    Journal of the American College of Surgeons, 2006, Volume: 202, Issue:1

    Topics: Blood Preservation; CD11b Antigen; Cell Culture Techniques; Culture Media; Erythrocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Pentoxifylline; Phosphodiesterase Inhibitors; Receptors, Complement 3b; Reference Values; Respiratory Burst

2006
Neutrophil degranulation and the effects of phosphodiesterase inhibition.
    The Journal of surgical research, 2006, Jun-01, Volume: 133, Issue:1

    Topics: Adult; Antigens, CD; Cell Adhesion Molecules; Cell Degranulation; Down-Regulation; GPI-Linked Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Receptors, Complement 3b; Secretory Vesicles

2006
The effects of a novel resuscitation strategy combining pentoxifylline and hypertonic saline on neutrophil MAPK signaling.
    Surgery, 2007, Volume: 142, Issue:2

    Topics: Cell Size; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Pentoxifylline; Saline Solution, Hypertonic

2007
Pentoxifylline modulates p47phox activation and downregulates neutrophil oxidative burst through PKA-dependent and -independent mechanisms.
    Immunopharmacology and immunotoxicology, 2010, Volume: 32, Issue:1

    Topics: Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Humans; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-akt; raf Kinases; ras Proteins; Respiratory Burst

2010