Page last updated: 2024-08-25

n-formylglycine and glycine

n-formylglycine has been researched along with glycine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's1 (2.63)18.2507
2000's7 (18.42)29.6817
2010's18 (47.37)24.3611
2020's11 (28.95)2.80

Authors

AuthorsStudies
Inomata, K; Kusano, Y; Yamagata, Y1
Kumar, S; Punekar, NS1
Beringer, M; Rodnina, MV; Sievers, A; Wolfenden, R1
Close, DM; Hole, EO; Nelson, WH; Sagstuen, E; Vågane, R1
Dierks, T; Gande, SL; Mariappan, M; Pringle, TH; Schmidt, B; von Figura, K1
Dierks, T; Gande, SL; Mariappan, M; Radhakrishnan, K; Schmidt, B; von Figura, K1
Ballister, ER; Berger, JM; Bertozzi, CR; Breidenbach, MA; Carlson, BL; Gilmore, SA; King, DS; Skordalakes, E1
Bertozzi, CR; Rush, JS1
Hollfelder, F; Hyvönen, M; Jonas, S; van Loo, B1
Dierks, T; Ennemann, EC; Mariappan, M; Pringle, TH; Radhakrishnan, K; Schmidt, B; Wachs, M1
Denehy, E; Krenske, EH; Williams, SJ1
Engi, P; Knop, M; Lemnaru, R; Seebeck, FP1
Harasink, SM; Khurana, DS; Legido, A; Melvin, JJ; Miskin, C; Wenger, DA1
Christiansen, O; Godtliebsen, IH; Hansen, MB; König, C1
Bai, Y; Gao, R; Jian, H; Li, R; Wang, Y1
Dang, TQ; Jeschke, G; Knop, M; Seebeck, FP1
Knop, M; Meury, M; Seebeck, FP1
Babicz, M; Dierks, T; Jaszczuk, I; Koppenhöfer, D; Lejman, M; Ohlenbusch, A; Radhakrishnan, K; Schlotawa, L; Ługowska, A1
Knop, M; Lemnaru, R; Seebeck, FP1
Chadah, T; Meshach Paul, D; Rajasekaran, R; Senthilkumar, B; Sethumadhavan, R1
Barfield, RM; Rabuka, D1
Fischer, L; Glück, C; Kuhn, A; Leptihn, S; Pfannstiel, J; Reichenberger, K; Seitl, I; Stressler, T; Swietalski, P1
Alam, S; Boschanski, M; Dierks, T; Falck, G; Gerlach, M; Krüger, T; Müller, KM; Sewald, N; Weiland, S1
Bernhard, O; Dierks, T; Mayer, FJ; Radhakrishnan, K; Schlotawa, L; Schmidt, B; Wachs, M1
Dierks, T; Krüger, T; Sewald, N1
Appel, MJ; Bertozzi, CR; Hedman, B; Hodgson, KO; Lafrance-Vanasse, J; Lim, H; Meier, KK; Solomon, EI; Tainer, JA; Tsai, CL1
Barfield, RM; Liu, J; Rabuka, D1
Adang, LA; Ahrens-Nicklas, RC; Radhakrishnan, K; Schlotawa, L1
Adang, LA; Ahrens-Nicklas, R; Friede, T; Gärtner, J; Preiskorn, J; Schiller, S; Schlotawa, L1
Adang, LA; Ahrens-Nicklas, RC; Costin, C; De Castro, M; Dierks, T; Gärtner, J; Groeschel, S; Harzer, K; Kehrer, C; Montgomery, EF; Radhakrishnan, K; Schlotawa, L; Schwartz, IVD; Silva, TO; Staretz-Chacham, O1
Boschanski, M; Dierks, T; Janson, N; Karsten, L; Krüger, T; Müller, KM; Sewald, N1
Chouichit, P; Loprasert, S; Mongkolsuk, S; Sallabhan, R; Whangsuk, W1
Damme, M; Lübke, T1
Alam, S; Boschanski, M; Dierks, T; Falck, G; Gerlach, M; Karsten, L; Krüger, T; Müller, B; Müller, KM; Sewald, N1
Bosis, E; Feldman, MF; Le, NH; Lopez, J; Moon, KH; Salomon, D1
Huang, C; Ji, F; Jia, L; Li, D; Muyldermans, S; Peng, Q; Ren, J; Zang, B1
Bag, J; Barman, S; Bose, M; Moula, G; Pal, K1
Arkona, C; Bergemann, S; Keller, BG; Martos, V; Nawrotzky, E; Rademann, J; Schmieder, P; Song, W; Tiemann, M; Wehrhan, L1

Reviews

4 review(s) available for n-formylglycine and glycine

ArticleYear
Formylglycine-generating enzymes for site-specific bioconjugation.
    Biological chemistry, 2019, 02-25, Volume: 400, Issue:3

    Topics: Glycine; Humans; Models, Molecular; Molecular Structure; Sulfatases

2019
Multiple Sulfatase Deficiency: A Disease Comprising Mucopolysaccharidosis, Sphingolipidosis, and More Caused by a Defect in Posttranslational Modification.
    International journal of molecular sciences, 2020, May-13, Volume: 21, Issue:10

    Topics: Glycine; Humans; Mucopolysaccharidoses; Multiple Sulfatase Deficiency Disease; Mutation; Oxidoreductases Acting on Sulfur Group Donors; Protein Processing, Post-Translational; Sphingolipidoses; Sulfatases

2020
A systematic review and meta-analysis of published cases reveals the natural disease history in multiple sulfatase deficiency.
    Journal of inherited metabolic disease, 2020, Volume: 43, Issue:6

    Topics: Glycine; Humans; Leukodystrophy, Metachromatic; Mucopolysaccharidoses; Multiple Sulfatase Deficiency Disease; Oxidoreductases Acting on Sulfur Group Donors; Protein Processing, Post-Translational; Sulfatases

2020
Lysosomal sulfatases: a growing family.
    The Biochemical journal, 2020, 10-30, Volume: 477, Issue:20

    Topics: Animals; Catalytic Domain; Disease Models, Animal; Endoplasmic Reticulum; Glycine; Humans; Lysosomal Storage Diseases; Lysosomes; Phylogeny; Protein Processing, Post-Translational; Sulfatases

2020

Other Studies

34 other study(ies) available for n-formylglycine and glycine

ArticleYear
Amino acids derivatives synthesis from nitrogen, carbon and water by electric discharges.
    Origins of life, 1981, Volume: 11, Issue:4

    Topics: Amino Acids; Carbon; Chromatography, Gas; Diketopiperazines; Electricity; Glycine; Hydrolysis; Nitrogen; Piperazines; Pressure; Serine; Urea; Water

1981
Inhibition of succinic semialdehyde dehydrogenase by N-formylglycine.
    Journal of enzyme inhibition, 1998, Volume: 13, Issue:5

    Topics: Aldehyde Oxidoreductases; Aspergillus niger; Enzyme Inhibitors; Glycine; Solanum tuberosum; Succinate-Semialdehyde Dehydrogenase

1998
The ribosome as an entropy trap.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, May-25, Volume: 101, Issue:21

    Topics: Binding Sites; Catalysis; Entropy; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Protein Biosynthesis; Protons; Ribosomes; Temperature; Tromethamine; Viscosity; Water

2004
Electron transfer in amino acid.nucleic acid base complexes: EPR, ENDOR, and DFT study of X-irradiated N-formylglycine.cytosine complex crystals.
    The journal of physical chemistry. A, 2006, Jul-20, Volume: 110, Issue:28

    Topics: Amino Acids; Base Pairing; Crystallization; Cytosine; Electron Spin Resonance Spectroscopy; Electron Transport; Glycine; Models, Chemical; Models, Molecular; Molecular Structure; Nucleic Acids; Oxidation-Reduction; Spectrum Analysis

2006
Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.
    The FEBS journal, 2008, Volume: 275, Issue:6

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Computational Biology; Conserved Sequence; Endoplasmic Reticulum; Evolution, Molecular; Glycine; Humans; Molecular Sequence Data; Oxidoreductases Acting on Sulfur Group Donors; Protein Conformation; Protein Sorting Signals; Sulfatases

2008
The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum.
    The Journal of biological chemistry, 2008, Apr-25, Volume: 283, Issue:17

    Topics: Catalysis; Catalytic Domain; Cell Line, Tumor; Cells, Cultured; Endoplasmic Reticulum; Fluorescent Antibody Technique, Indirect; Glycine; Humans; Models, Biological; Oxidoreductases Acting on Sulfur Group Donors; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sulfatases

2008
Function and structure of a prokaryotic formylglycine-generating enzyme.
    The Journal of biological chemistry, 2008, Jul-18, Volume: 283, Issue:29

    Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Glycine; Humans; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Protein Structure, Tertiary; Sequence Alignment; Streptomyces coelicolor; Structural Homology, Protein; Sulfatases

2008
New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo.
    Journal of the American Chemical Society, 2008, Sep-17, Volume: 130, Issue:37

    Topics: Aldehydes; Glycine; Models, Molecular; Muscle Stretching Exercises; Mycobacterium tuberculosis; Peptide Library; Peptides; Recombinant Proteins; Streptomyces coelicolor; Sulfatases

2008
A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium leguminosarum.
    Journal of molecular biology, 2008, Dec-05, Volume: 384, Issue:1

    Topics: Alkaline Phosphatase; Binding Sites; Catalysis; Crystallography, X-Ray; Evolution, Molecular; Glycine; Hydrolysis; Kinetics; Metals; Models, Molecular; Mutagenesis; Mutant Proteins; Phosphoric Diester Hydrolases; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Rhizobium leguminosarum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity; Structural Homology, Protein; Substrate Specificity

2008
Proprotein convertases process and thereby inactivate formylglycine-generating enzyme.
    The Journal of biological chemistry, 2013, Feb-22, Volume: 288, Issue:8

    Topics: Amino Acid Motifs; Animals; Arginine; Binding Sites; Cell Line, Tumor; CHO Cells; Cricetinae; Endoplasmic Reticulum; Enzyme Inhibitors; Furin; Glycine; HEK293 Cells; HeLa Cells; Homeostasis; Humans; Oxidoreductases Acting on Sulfur Group Donors; Plasmids; Proprotein Convertases; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteolysis; Sulfatases; Tyrosine

2013
Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of type I sulfatase inactivation by aryl sulfamates.
    The Journal of organic chemistry, 2014, Mar-07, Volume: 79, Issue:5

    Topics: Binding Sites; Catalysis; Esters; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Models, Theoretical; Sulfatases; Sulfates; Sulfonic Acids; Sulfuric Acid Esters

2014
In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I).
    Chembiochem : a European journal of chemical biology, 2015, Oct-12, Volume: 16, Issue:15

    Topics: Actinobacteria; Biocatalysis; Copper; Glycine; Molecular Structure; Mycobacterium smegmatis; Oxygen; Sulfatases

2015
A Patient With Atypical Multiple Sulfatase Deficiency.
    Pediatric neurology, 2016, Volume: 57

    Topics: Cerebroside-Sulfatase; Child, Preschool; Female; Glycine; Humans; Magnetic Resonance Imaging; Multiple Sulfatase Deficiency Disease; Mutation; White Matter

2016
FALCON: A method for flexible adaptation of local coordinates of nuclei.
    The Journal of chemical physics, 2016, Feb-21, Volume: 144, Issue:7

    Topics: Algorithms; Conotoxins; Coumarins; Glycine; Models, Chemical; Molecular Structure; Oligopeptides; Vibration

2016
Site-Specific, Covalent Immobilization of Dehalogenase ST2570 Catalyzed by Formylglycine-Generating Enzymes and Its Application in Batch and Semi-Continuous Flow Reactors.
    Molecules (Basel, Switzerland), 2016, Jul-11, Volume: 21, Issue:7

    Topics: Aldehydes; Bioreactors; Catalysis; Enzyme Stability; Enzymes, Immobilized; Fermentation; Glycine; Hydrogen-Ion Concentration; Hydrolases; Hydrolysis; Models, Molecular; Molecular Conformation; Silicon Dioxide; Thermodynamics

2016
Copper is a Cofactor of the Formylglycine-Generating Enzyme.
    Chembiochem : a European journal of chemical biology, 2017, Jan-17, Volume: 18, Issue:2

    Topics: Actinobacteria; Biocatalysis; Catalytic Domain; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Glycine; Humans; Kinetics; Molecular Dynamics Simulation; Sulfatases

2017
Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.
    Angewandte Chemie (International ed. in English), 2017, 07-03, Volume: 56, Issue:28

    Topics: Actinobacteria; Binding Sites; Catalysis; Catalytic Domain; Coordination Complexes; Copper; Crystallography, X-Ray; Cysteine; Enzymes; Glycine; Ligands; Metalloproteins; Oxidation-Reduction; Oxygen; Protein Conformation

2017
Expanding the genetic cause of multiple sulfatase deficiency: A novel SUMF1 variant in a patient displaying a severe late infantile form of the disease.
    Molecular genetics and metabolism, 2017, Volume: 121, Issue:3

    Topics: Cells, Cultured; Child, Preschool; Computer Simulation; Enzymes; Glycine; Humans; Ichthyosis; Male; Multiple Sulfatase Deficiency Disease; Mutation, Missense; Oxidoreductases Acting on Sulfur Group Donors; Phenotype; Poland; Protein Processing, Post-Translational; Sulfatases

2017
Mutation of Conserved Residues Increases in Vitro Activity of the Formylglycine-Generating Enzyme.
    Chembiochem : a European journal of chemical biology, 2017, 09-05, Volume: 18, Issue:17

    Topics: Actinobacteria; Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Enzymes; Escherichia coli; Glycine; Humans; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment

2017
Structural distortions due to missense mutations in human formylglycine-generating enzyme leading to multiple sulfatase deficiency.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:13

    Topics: Amino Acid Substitution; Glycine; Humans; Models, Molecular; Molecular Dynamics Simulation; Multiple Sulfatase Deficiency Disease; Mutation, Missense; Oxidoreductases Acting on Sulfur Group Donors; Protein Structure, Secondary; Sulfatases

2018
Leveraging Formylglycine-Generating Enzyme for Production of Site-Specifically Modified Bioconjugates.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1728

    Topics: Aldehydes; Animals; Antibodies, Monoclonal; Catalysis; Cell Line; CHO Cells; Chromatography, Liquid; Cricetulus; Cysteine; Enzymes; Glycine; Humans; Immunoconjugates; Mutagenesis, Site-Directed; Substrate Specificity; Tandem Mass Spectrometry

2018
A natural variant of arylsulfatase from Kluyveromyces lactis shows no formylglycine modification and has no enzyme activity.
    Applied microbiology and biotechnology, 2018, Volume: 102, Issue:6

    Topics: Arylsulfatases; Biotransformation; Cloning, Molecular; Escherichia coli; Gene Expression; Glycine; Kluyveromyces; Mass Spectrometry; Mutant Proteins; Protein Structure, Secondary; Spectrum Analysis

2018
Two-fold Bioorthogonal Derivatization by Different Formylglycine-Generating Enzymes.
    Angewandte Chemie (International ed. in English), 2018, 06-11, Volume: 57, Issue:24

    Topics: Bacteria; Cell Line; Cysteine; Glycine; Humans; Iron-Sulfur Proteins; Methanosarcina; Oxidation-Reduction; Sulfatases

2018
Recognition and ER Quality Control of Misfolded Formylglycine-Generating Enzyme by Protein Disulfide Isomerase.
    Cell reports, 2018, 07-03, Volume: 24, Issue:1

    Topics: Amino Acid Sequence; Disulfides; Endoplasmic Reticulum; Enzyme Stability; Glycine; Humans; Multiple Sulfatase Deficiency Disease; Mutant Proteins; Mutation; Oxidoreductases Acting on Sulfur Group Donors; Peptides; Protein Disulfide-Isomerases; Protein Folding

2018
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-19, Volume: 116, Issue:12

    Topics: Catalysis; Catalytic Domain; Copper; Crystallography, X-Ray; Cysteine; Glycine; Oxidation-Reduction; Oxygen; Sulfatases

2019
Site-Specific Bioconjugation Using SMARTag
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 2033

    Topics: Aldehydes; Glycine; Humans; Immunoconjugates; Oxidoreductases Acting on Sulfur Group Donors; Peptides; Protein Engineering; Protein Processing, Post-Translational; Proteins

2019
Natural history of multiple sulfatase deficiency: Retrospective phenotyping and functional variant analysis to characterize an ultra-rare disease.
    Journal of inherited metabolic disease, 2020, Volume: 43, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Female; Genotype; Glycine; Humans; Infant; Internationality; Leukodystrophy, Metachromatic; Male; Mucopolysaccharidoses; Multiple Sulfatase Deficiency Disease; Mutation; Oxidoreductases Acting on Sulfur Group Donors; Phenotype; Rare Diseases; Retrospective Studies; Sulfatases

2020
Bifunctional Reagents for Formylglycine Conjugation: Pitfalls and Breakthroughs.
    Chembiochem : a European journal of chemical biology, 2020, 12-11, Volume: 21, Issue:24

    Topics: Azides; Cross-Linking Reagents; ErbB Receptors; Fluorescent Dyes; Glycine; Humans; Molecular Structure; Optical Imaging; Tumor Cells, Cultured

2020
A highly sensitive biosensor with a single-copy evolved sensing cassette for chlorpyrifos pesticide detection.
    Microbiology (Reading, England), 2020, Volume: 166, Issue:11

    Topics: Bacterial Proteins; Biosensing Techniques; Chlorpyrifos; Directed Molecular Evolution; Escherichia coli; Glycine; Limit of Detection; Pesticides; Piperazines; Promoter Regions, Genetic; Recombinant Proteins; Sinorhizobium meliloti; Sulfatases; Transcription Factors

2020
Site-Specific Conjugation Strategy for Dual Antibody-Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes.
    Bioconjugate chemistry, 2021, 06-16, Volume: 32, Issue:6

    Topics: Aerobiosis; Ankyrin Repeat; Copper; Enzymes; Fluoresceins; Glycine; Immunoconjugates; Oligopeptides

2021
Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins.
    Journal of bacteriology, 2021, 10-12, Volume: 203, Issue:21

    Topics: Acinetobacter baumannii; Bacterial Proteins; Blotting, Western; Glycine; Models, Molecular; Protein Conformation; Type VI Secretion Systems

2021
Cytoplasmic Expression of Nanobodies with Formylglycine Generating Enzyme Tag and Conversion to a Bio-Orthogonal Aldehyde Group.
    Methods in molecular biology (Clifton, N.J.), 2022, Volume: 2446

    Topics: Aldehydes; Cysteine; Glycine; Single-Domain Antibodies

2022
Oxygen Activation by a Copper Complex with Sulfur-Only Coordination Relevant to the Formylglycine Generating Enzyme.
    Inorganic chemistry, 2022, May-02, Volume: 61, Issue:17

    Topics: Copper; Electron Spin Resonance Spectroscopy; Glycine; Ligands; Oxygen; Sulfur

2022
A Formylglycine-Peptide for the Site-Directed Identification of Phosphotyrosine-Mimetic Fragments.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2022, Oct-12, Volume: 28, Issue:57

    Topics: Acetates; Amino Acids; Binding Sites; Glycine; Molecular Probes; Peptides; Phosphotyrosine

2022