n-ethoxycarbonyl-7-oxostaurosporine has been researched along with staurosporine in 9 studies
| Studies (n-ethoxycarbonyl-7-oxostaurosporine) | Trials (n-ethoxycarbonyl-7-oxostaurosporine) | Recent Studies (post-2010) (n-ethoxycarbonyl-7-oxostaurosporine) | Studies (staurosporine) | Trials (staurosporine) | Recent Studies (post-2010) (staurosporine) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 6,272 | 58 | 976 |
| Protein | Taxonomy | n-ethoxycarbonyl-7-oxostaurosporine (IC50) | staurosporine (IC50) |
|---|---|---|---|
| Chain A, Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | 0.0003 | |
| Chain X, Tyrosine-protein kinase Lyn | Homo sapiens (human) | 0.0013 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inoko, K; Koyama, M; Miyamoto, K; Takagi, K; Wakusawa, S | 1 |
| Koga, K; Miyamoto, K; Ohshima, T; Takeda, K; Wakusawa, S | 1 |
| Hasegawa, T; Inoko, K; Kajita, S; Koyama, M; Miyamoto, K; Takagi, K; Wakusawa, S | 1 |
| Koga, K; Koga-Takeda, K; Miyamoto, KI; Nomura, M; Ohshima, T | 1 |
| Miyamoto, K; Nomura, M; Sugiura, N | 1 |
| Miyamoto, K; Moritani, S; Nomura, M; Sugiura, N | 1 |
| Miyamoto, K; Nomura, M; Sugiura, N; Yamamoto, H | 1 |
| Choung, SY; Kwon, H | 1 |
| Horita, T; Miyamoto, K; Moritani, S; Suzuki, R; Waki, Y; Yamamoto, S | 1 |
9 other study(ies) available for n-ethoxycarbonyl-7-oxostaurosporine and staurosporine
| Article | Year |
|---|---|
Reversal of vinblastine resistance by a new staurosporine derivative, NA-382, in P388/ADR cells.
Topics: Affinity Labels; Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Division; Cell Line; Cell Membrane; Dihydropyridines; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Leukemia P388; Membrane Glycoproteins; Protein Kinase C; Staurosporine; Vinblastine | 1992 |
Antitumour effects and pharmacokinetics of combination of vinblastine with a staurosporine derivative, NA-382, in P388/ADR-bearing mice.
Topics: Alkaloids; Animals; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Resistance, Multiple; Female; Leukemia P388; Mice; Mice, Inbred Strains; Protein Kinase C; Staurosporine; Tumor Cells, Cultured; Verapamil; Vinblastine | 1995 |
Inhibition of multidrug resistance by a new staurosporine derivative, NA-382, in vitro and in vivo.
Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Female; Humans; In Vitro Techniques; Leukemia P388; Membrane Glycoproteins; Mice; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine | 1993 |
Saturable function of P-glycoprotein as a drug-efflux pump in multidrug-resistant tumour cells.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Leukemia P388; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Rats; Staurosporine; Tumor Cells, Cultured; Vinblastine | 1996 |
A protein kinase C inhibitor NA-382 prolongs the life span of AH66F-bearing rats as well as inhibiting leukocyte function-associated antigen-1 (LFA-1)-dependent adhesion of the cells.
Topics: Alkaloids; Animals; Cell Adhesion; Enzyme Inhibitors; Female; Flow Cytometry; Life Expectancy; Liver Neoplasms, Experimental; Lymphocyte Function-Associated Antigen-1; Protein Kinase C; Rats; Staurosporine; Tumor Cells, Cultured | 1996 |
Inhibition by protein kinase C inhibitor of expression of leukocyte function-associated antigen-1 molecules in rat hepatoma AH66F cells.
Topics: Alkaloids; Animals; Cell Adhesion; DNA Primers; Enzyme Inhibitors; Flow Cytometry; Liver Neoplasms, Experimental; Lymphocyte Function-Associated Antigen-1; Macromolecular Substances; Mesentery; Polymerase Chain Reaction; Protein Kinase C; Rats; Staurosporine; T-Lymphocytes; Tumor Cells, Cultured | 1997 |
Leukocyte function-associated antigen 1-dependent adhesion of rat hepatoma AH66F cells and inhibition by protein kinase C inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies, Monoclonal; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Female; Intercellular Adhesion Molecule-1; Isoquinolines; Liver Neoplasms, Experimental; Lymphocyte Function-Associated Antigen-1; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tumor Cells, Cultured | 1997 |
Induction of differentiation of U-937 cells by 2-chloro-3-amino-1,4-naphthoquinone.
Topics: Alkaloids; Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Isoquinolines; Naphthol AS D Esterase; Naphthoquinones; Nitroblue Tetrazolium; Phagocytosis; Protein Kinase C; Staurosporine; Sulfonamides; Tumor Cells, Cultured | 1997 |
Dual regulation of alkaline phosphatase activity by calcitonin in porcine kidney cells.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Calcitonin; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Kidney; LLC-PK1 Cells; Protein Kinase C; Signal Transduction; Staurosporine; Swine | 1997 |