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n-epsilon-acetyllysine and lysine

n-epsilon-acetyllysine has been researched along with lysine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199011 (25.58)18.7374
1990's13 (30.23)18.2507
2000's13 (30.23)29.6817
2010's6 (13.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blount, KF; Breaker, RR; Lim, J; Sudarsan, N; Wang, JX1
Barker, HA; Bozler, G; Hensley, C; Ohsugi, M; Robertson, JM1
Bode, R; Schmidt, H1
Large, PJ; Robertson, A1
Gunsalus, RP; Noll, D; Roberts, MF; Robertson, DE; Sowers, KR1
Crane-Robinson, C; Hebbes, TR; Thorne, AW; Turner, CH1
Deutsch, HF; Jabusch, JR1
Blue, WT; Cohen, BN; Wagner, TE1
Perheentupa, J; Rajantie, J; Simell, O1
Dyroff, MC; Neal, RA2
Allfrey, VG; Di Paola, EA; Sterner, R1
Chang, YF; Hernandez, MF1
Duffin, KL; Kane, JF; Kolodziej, EW; Lawson, CQ; Schlittler, MR; Siegel, NR; Smith, CE; Violand, BN1
Henle, T; Klostermeyer, H; Walter, AW1
Cohn, JA; Friguet, B; Szweda, LI; Tsai, L1
Gineitis, A; Jasinskas, A; Jasinskiene, N; Kersulyte, D; Langmore, J; Steponaviciute, D1
Clayton, AL; Crane-Robinson, C; Hebbes, TR; Thorne, AW1
Crowley, JR; d'Avignon, A; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF1
Bausch, JN; Gruber, SC; Patel, ST; Pflumm, MN; Pramanik, B; Tsarbopoulos, A; Wylie, D1
Trivedi, VD1
Anderson, MM; d'Avignon, A; Hazen, SL; Heinecke, JW; Hsu, FF1
Amano, T; Aratani, S; Fujii, R; Fukamizu, A; Hagiwara, M; Inoue, K; Kawahara, K; Maruyama, I; Nakajima, T; Nakata, M; Ohshima, T; Oishi, T; Shibata, M; Soejima, Y; Watanabe, S; Yanai, K1
Jacobson, RH; King, DS; Ladurner, AG; Tjian, R1
Haas, AL; London, RE; Macdonald, JM1
Brosch, G; Hoffmann, K; Jung, M; Loidl, P1
Ciulla, RA; Martin, DD; Roberts, MF; Robinson, PM1
Dyson, HJ; Hudson, BP; Martinez-Yamout, MA; Wright, PE1
Komatsu, Y; Yoshida, M; Yukutake, Y1
DEMAIN, AL; HENDLIN, D; NEWKIRK, JF1
KIM, S; PAIK, WK1
Conn, MT; Misialek, S; Schultz, BE; Tahilramani, R; Tang, J; Wong, L; Wu, J1
Iwabata, H; Komatsu, Y; Yoshida, M1
Fatkins, DG; Jamonnak, N; Wei, L; Zheng, W1
Chin, JW; Neumann, H; Peak-Chew, SY1
Jensen, ON; Trelle, MB1
Cen, Y; French, JB; Sauve, AA1
Huang, Y; Liu, W; Pai, PJ; Russell, DH; Russell, WK; Wan, W1
Cen, Y; Sauve, AA1
Bowman, CM; Christianson, DW; D'Antonio, EL; Genshaft, A; Moser, JA1
Curthoys, NP; Freund, DM; Prenni, JE1
Bierczyńska-Krzysik, A; Mak, P; Piejko, M; Stadnik, D; Szewczak, J1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F1

Other Studies

43 other study(ies) available for n-epsilon-acetyllysine and lysine

ArticleYear
Antibacterial lysine analogs that target lysine riboswitches.
    Nature chemical biology, 2007, Volume: 3, Issue:1

    Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacteria; Gene Expression Regulation, Bacterial; Lysine; Microbial Sensitivity Tests; Molecular Structure; Nucleic Acid Conformation; Regulatory Elements, Transcriptional; RNA, Bacterial

2007
Metabolism of L-beta-lysine in a Pseudomonas: conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by different transaminases.
    Archives of biochemistry and biophysics, 1979, Oct-01, Volume: 197, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Enzyme Induction; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Substrate Specificity; Transaminases

1979
Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa.
    Antonie van Leeuwenhoek, 1992, Volume: 62, Issue:4

    Topics: Candida; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Lysine; Molecular Weight; Transaminases

1992
The route of lysine breakdown in Candida tropicalis.
    FEMS microbiology letters, 1991, Aug-01, Volume: 66, Issue:2

    Topics: Acetates; Acetic Acid; Acetyltransferases; Candida; Glutamates; Glutamic Acid; Kinetics; Lysine; Rhodotorula; Temperature; Transaminases

1991
N epsilon-acetyl-beta-lysine: an osmolyte synthesized by methanogenic archaebacteria.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:23

    Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Euryarchaeota; Glutamates; Lysine; Magnetic Resonance Spectroscopy

1990
A "minimal epitope" anti-protein antibody that recognises a single modified amino acid.
    Molecular immunology, 1989, Volume: 26, Issue:9

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Chromatin; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epitopes; Histones; Immunoblotting; Lysine; Rabbits

1989
Localization of lysines acetylated in ubiquitin reacted with p-nitrophenyl acetate.
    Archives of biochemistry and biophysics, 1985, Volume: 238, Issue:1

    Topics: Acetylation; Amino Acids; Animals; Buffers; Cattle; Chemical Phenomena; Chemistry; Electrophoresis, Disc; High Mobility Group Proteins; Horses; Lysine; Malonates; Nitrophenols; Peptide Fragments; Ubiquitins

1985
Chemically induced gene expression. Manipulation of the transforming ability of simian virus 40 minichromatin by specific chemical hyperacetylation of histones H3 and H4.
    European journal of biochemistry, 1980, Volume: 107, Issue:2

    Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Antigens, Viral, Tumor; Cell Transformation, Viral; Cells, Cultured; Chromatin; Histones; Lysine; Methylcellulose; Mice; Simian virus 40

1980
Oral administration of epsilon N-acetyllysine and homocitrulline in lysinuric protein intolerance.
    The Journal of pediatrics, 1983, Volume: 102, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Citrulline; Female; Humans; Lysine; Male

1983
Studies of the mechanism of metabolism of thioacetamide s-oxide by rat liver microsomes.
    Molecular pharmacology, 1983, Volume: 23, Issue:1

    Topics: Acetamides; Animals; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Lysine; Male; Microsomes, Liver; Models, Chemical; Oxygenases; Rats; Serum Albumin, Bovine; Thioacetamide

1983
Protein side-chain acetylations.
    Methods in enzymology, 1984, Volume: 107

    Topics: Acetylation; Acetyltransferases; Animals; Carbon Isotopes; Carbon Radioisotopes; Cell Nucleus; Chromatography, Ion Exchange; Histones; Indicators and Reagents; Liver; Lysine; Protein Processing, Post-Translational; Proteins; Radioisotope Dilution Technique; Rats; Substrate Specificity; Tritium

1984
In vitro synthesis of L-pipecolate from L-lysine: inconsistent with epsilon-N-acetyl-L-lysine as an obligatory intermediate.
    Biochemical and biophysical research communications, 1980, Apr-14, Volume: 93, Issue:3

    Topics: Animals; Brain; Carbon Radioisotopes; Cytosol; Kidney; Lysine; Male; Mitochondria; Pipecolic Acids; Rats

1980
Identification of the major protein adduct formed in rat liver after thioacetamide administration.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Acetamides; Amino Acids; Animals; Chromatography, Ion Exchange; Gas Chromatography-Mass Spectrometry; Liver; Lysine; Male; Proteins; Rats; Thioacetamide

1981
Isolation of Escherichia coli synthesized recombinant eukaryotic proteins that contain epsilon-N-acetyllysine.
    Protein science : a publication of the Protein Society, 1994, Volume: 3, Issue:7

    Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Escherichia coli; Growth Hormone; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoelectric Point; Lysine; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Swine; Trypsin

1994
A simple method for the preparation of furosine and pyridosine reference material.
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1994, Volume: 198, Issue:1

    Topics: Amino Acids; Chromatography, Ion Exchange; Glucose; Glycosylation; Hot Temperature; Hydrolysis; Lysine; Reference Standards

1994
Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress.
    Archives of biochemistry and biophysics, 1996, Apr-01, Volume: 328, Issue:1

    Topics: Aldehydes; Animals; Cross-Linking Reagents; Glucosephosphate Dehydrogenase; Histidine; Immunochemistry; Lipid Peroxidation; Lysine; Male; Mitochondria, Liver; Models, Chemical; Oxidative Stress; Proteins; Rats; Rats, Inbred F344; Schiff Bases

1996
Turnover of histone acetyl groups during sea urchin early development is not required for histone, heat shock and actin gene transcription.
    Biochimica et biophysica acta, 1997, Mar-20, Volume: 1351, Issue:1-2

    Topics: Acetylation; Actins; Animals; Butyrates; Butyric Acid; Chromatin; Embryo, Nonmammalian; Embryonic Development; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Heat-Shock Proteins; Histone Deacetylase Inhibitors; Histones; Lysine; Sea Urchins; Transcription, Genetic

1997
Chromosomal mapping of core histone acetylation by immunoselection.
    Methods (San Diego, Calif.), 1997, Volume: 12, Issue:1

    Topics: Acetylation; Animals; Antibodies; Chick Embryo; Chromatin; Chromatography, Affinity; Chromosomes; DNA; DNA Probes; Gene Expression Regulation; Globins; Histones; Humans; Lysine; Nucleic Acid Hybridization; Nucleosomes; Platelet-Derived Growth Factor; Tissue Plasminogen Activator; Transcription, Genetic; Tumor Cells, Cultured

1997
p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues.
    The Journal of biological chemistry, 1997, Jul-04, Volume: 272, Issue:27

    Topics: Acetaldehyde; Amino Acids; Animals; Cattle; Chlorides; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Inflammation; Lysine; Magnetic Resonance Spectroscopy; Neutrophils; Peroxidase; Phagocytes; Phenol; Proteins; Schiff Bases; Serum Albumin, Bovine; Tyrosine

1997
Isolation and characterization of an acetylated impurity in Escherichia coli-derived recombinant human interleukin-10 (IL-10) drug substance.
    Pharmaceutical research, 1997, Volume: 14, Issue:6

    Topics: Chromatography, High Pressure Liquid; Drug Contamination; Escherichia coli; Humans; Interleukin-10; Lysine; Mass Spectrometry; Recombinant Proteins

1997
On the role of lysine residues in the bromophenol blue-albumin interaction.
    The Italian journal of biochemistry, 1997, Volume: 46, Issue:2

    Topics: Acetylation; Animals; Bromphenol Blue; Cattle; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Spectrophotometry

1997
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Aldehydes; Amino Acids; Chloramines; Chlorides; Humans; Hypochlorous Acid; Lysine; Mass Spectrometry; Models, Chemical; Neutrophils; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine

1998
Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1999, Dec-20, Volume: 266, Issue:2

    Topics: Acetylation; Antibodies; Butadienes; Cadaver; Cells, Cultured; Coronary Artery Disease; CREB-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Hemagglutinins; Humans; Immunohistochemistry; Lysine; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitriles; Nuclear Proteins; Thrombin; Trans-Activators; Transfection

1999
Structure and function of a human TAFII250 double bromodomain module.
    Science (New York, N.Y.), 2000, May-26, Volume: 288, Issue:5470

    Topics: Acetylation; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; DNA-Binding Proteins; Histone Acetyltransferases; Histones; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; TATA-Binding Protein Associated Factors; Transcription Factor TFIID; Transcription, Genetic

2000
Novel mechanism of surface catalysis of protein adduct formation. NMR studies of the acetylation of ubiquitin.
    The Journal of biological chemistry, 2000, Oct-13, Volume: 275, Issue:41

    Topics: Acetic Anhydrides; Acetylation; Amino Acid Substitution; Aspirin; Carbon Isotopes; Catalysis; Glycation End Products, Advanced; Histidine; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Surface Properties; Ubiquitins

2000
First non-radioactive assay for in vitro screening of histone deacetylase inhibitors.
    Die Pharmazie, 2000, Volume: 55, Issue:8

    Topics: Aminocaproic Acid; Animals; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Liver; Lysine; Rats; Spectrometry, Fluorescence

2000
Switching osmolyte strategies: response of Methanococcus thermolithotrophicus to changes in external NaCl.
    Biochimica et biophysica acta, 2001, Nov-15, Volume: 1524, Issue:1

    Topics: Chromatography, High Pressure Liquid; Glutamates; Intramolecular Transferases; Lysine; Magnetic Resonance Spectroscopy; Methanococcus; Osmolar Concentration; Osmotic Pressure; Potassium; Sodium Chloride; Time Factors

2001
Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
    Journal of molecular biology, 2000, Dec-01, Volume: 304, Issue:3

    Topics: Acetamides; Amino Acid Sequence; Binding Sites; Cell Cycle Proteins; Histamine; Histone Acetyltransferases; Humans; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; p300-CBP Transcription Factors; Peptide Fragments; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Solutions; Static Electricity; Substrate Specificity; Trans-Activators; Transcription Factors

2000
Four different clones of mouse anti-acetyllysine monoclonal antibodies having different recognition properties share a common immunoglobulin framework structure.
    Journal of immunological methods, 2003, Jan-15, Volume: 272, Issue:1-2

    Topics: Acetylation; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Antigens; Base Sequence; Blotting, Western; Cloning, Molecular; Complementarity Determining Regions; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Hybridomas; Immunoglobulin Variable Region; In Vitro Techniques; Kinetics; Lysine; Mice; Molecular Sequence Data; Molecular Structure; Precipitin Tests; Proteins; Sequence Homology, Nucleic Acid

2003
Effect of methionine, norleucine, and lysine derivatives on cephalosporin C formation in chemically defined media.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Acremonium; Cephalosporins; Culture Media; Leucine; Lysine; Methionine; Norleucine

1963
ENZYMIC SYNTHESIS OF EPSILON-N-ACETYL-L-LYSINE.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: Amino Acids; Animals; Calcium; Calcium, Dietary; Carbon Isotopes; Cattle; Citrulline; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Magnesium; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Research; Spectrophotometry; Temperature; Transferases

1964
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases.
    Biochemistry, 2004, Aug-31, Volume: 43, Issue:34

    Topics: Binding Sites; Binding, Competitive; Coumarins; Enzyme Activation; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Isoenzymes; Kinetics; Lysine; Phosphorylation; Recombinant Proteins; Repressor Proteins; Substrate Specificity

2004
Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.
    Proteomics, 2005, Volume: 5, Issue:18

    Topics: Acetylation; Actins; Animals; Antibodies, Monoclonal; Brain Chemistry; Creatine Kinase, MM Form; Cross Reactions; Female; Histones; Horseradish Peroxidase; Hybridomas; Lysine; Methylation; Mice; Muscle Proteins; Muscle, Skeletal; Nerve Tissue Proteins; Organ Specificity; Protein Processing, Post-Translational; Proteomics; Tubulin

2005
N(epsilon)-methanesulfonyl-lysine as a non-hydrolyzable functional surrogate for N(epsilon)-acetyl-lysine.
    Organic & biomolecular chemistry, 2007, Mar-21, Volume: 5, Issue:6

    Topics: Chromatography, High Pressure Liquid; Histone Deacetylases; Humans; Hydrolysis; Lysine; Peptides; Repressor Proteins; Sirtuin 1; Sirtuins

2007
Genetically encoding N(epsilon)-acetyllysine in recombinant proteins.
    Nature chemical biology, 2008, Volume: 4, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Lysine; Methanosarcina barkeri; Models, Molecular; Molecular Conformation; Recombinant Proteins; RNA, Transfer

2008
Utility of immonium ions for assignment of epsilon-N-acetyllysine-containing peptides by tandem mass spectrometry.
    Analytical chemistry, 2008, May-01, Volume: 80, Issue:9

    Topics: Algorithms; Lysine; Peptides; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase.
    Biochemistry, 2008, Sep-23, Volume: 47, Issue:38

    Topics: Acetylation; Animals; Histones; Hydrolysis; Lysine; NAD; NAD+ Nucleosidase; Peptides; Plasmodium falciparum; Protozoan Proteins; Sirtuins

2008
A convenient method for genetic incorporation of multiple noncanonical amino acids into one protein in Escherichia coli.
    Molecular bioSystems, 2010, Volume: 6, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Codon, Terminator; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Green Fluorescent Proteins; Lysine; Models, Molecular; Molecular Sequence Data; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Ribosomal Proteins; Spectrometry, Mass, Electrospray Ionization; Systems Biology

2010
Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches.
    Journal of the American Chemical Society, 2010, Sep-08, Volume: 132, Issue:35

    Topics: Acetylation; Adenosine Diphosphate Ribose; Archaeoglobus fulgidus; Biocatalysis; Computer Simulation; Kinetics; Lysine; NAD; Sirtuin 2

2010
Energetically unfavorable amide conformations for N6-acetyllysine side chains in refined protein structures.
    Proteins, 2013, Volume: 81, Issue:6

    Topics: Amides; Databases, Protein; Isomerism; Lysine; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Thermodynamics

2013
Proteomic profiling of the mitochondrial inner membrane of rat renal proximal convoluted tubules.
    Proteomics, 2013, Volume: 13, Issue:16

    Topics: Animals; Chromatography, Liquid; Kidney Tubules, Proximal; Lysine; Mitochondrial Membranes; Mitochondrial Proteins; Proteome; Proteomics; Rats; Tandem Mass Spectrometry

2013
Isolation and Characterization of Acetylated Derivative of Recombinant Insulin Lispro Produced in Escherichia coli.
    Pharmaceutical research, 2015, Volume: 32, Issue:7

    Topics: Acetylation; Amino Acid Sequence; Chromatography, Ion Exchange; Escherichia coli; Insulin Lispro; Lysine; Molecular Sequence Data; Peptide Fragments; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Technology, Pharmaceutical

2015
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019