n-desmethyltrimebutine has been researched along with naloxone in 1 studies
| Studies (n-desmethyltrimebutine) | Trials (n-desmethyltrimebutine) | Recent Studies (post-2010) (n-desmethyltrimebutine) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 11 | 2 | 1 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | n-desmethyltrimebutine (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, D; Guilbaud, G; Kayser, V; Roman, F | 1 |
1 other study(ies) available for n-desmethyltrimebutine and naloxone
| Article | Year |
|---|---|
Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Hindlimb; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Pressure; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Stereoisomerism; Trimebutine | 2000 |