Page last updated: 2024-09-05

n-demethyltramadol and fluconazole

n-demethyltramadol has been researched along with fluconazole in 1 studies

Compound Research Comparison

Studies
(n-demethyltramadol)
Trials
(n-demethyltramadol)
Recent Studies (post-2010)
(n-demethyltramadol)
Studies
(fluconazole)
Trials
(fluconazole)
Recent Studies (post-2010) (fluconazole)
265189,3437213,664

Protein Interaction Comparison

ProteinTaxonomyn-demethyltramadol (IC50)fluconazole (IC50)
Lanosterol 14-alpha demethylaseCandida albicans SC53140.1296
Cytochrome P450 2C9 Homo sapiens (human)9.21
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.88

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Court, MH; Greene, SA; Grubb, TL; Joo, H; Kukanich, B; Mealey, KL; Perez Jimenez, TE1

Trials

1 trial(s) available for n-demethyltramadol and fluconazole

ArticleYear
Oral Coadministration of Fluconazole with Tramadol Markedly Increases Plasma and Urine Concentrations of Tramadol and the
    Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:1

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Cross-Over Studies; Dogs; Drug Interactions; Female; Fluconazole; Male; Pain; Random Allocation; Tramadol

2019