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n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine and melatonin

n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine has been researched along with melatonin in 4 studies

*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]

*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]

Compound Research Comparison

Studies
(n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine)
Trials
(n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine)
Recent Studies (post-2010)
(n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine)
Studies
(melatonin)
Trials
(melatonin)
Recent Studies (post-2010) (melatonin)
50023,2681,4519,627

Protein Interaction Comparison

ProteinTaxonomyn-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine (IC50)melatonin (IC50)
MyeloperoxidaseHomo sapiens (human)3
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)3.3323
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0004
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0005
Melatonin receptor type 1AHomo sapiens (human)0.0025
Melatonin receptor type 1BHomo sapiens (human)0.0035

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrieux, J; Guardiola-Lemaitre, B; Howell, HE; Lesieur, D; Morgan, PJ; Pfeiffer, B; Renard, P; Yous, S1
Caignard, DH; Delagrange, P; Depreux, P; Guardiola, B; Howell, HE; Lesieur, D; Mansour, HA; Morgan, P; Pfeiffer, B; Renard, P1
Andrieux, J; Brémont, B; Langlois, M; Mathé-Allainmat, M; Poncet, A; Serraz, I; Shen, S; Sicsic, S1
Chavatte, P; Guillaumet, G; Lesieur, D; Marot, C; Michel, A; Morin-Allory, L; Renard, P; Viaud, MC1

Other Studies

4 other study(ies) available for n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine and melatonin

ArticleYear
Novel naphthalenic ligands with high affinity for the melatonin receptor.
    Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

    Topics: Animals; Melatonin; Naphthalenes; Radioligand Assay; Rats; Receptors, Melatonin; Receptors, Neurotransmitter

1992
Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Acetamides; Animals; Cell Membrane; Colforsin; Cyclic AMP; Iodine Radioisotopes; Ligands; Melatonin; Molecular Structure; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Melatonin; Sheep; Structure-Activity Relationship

1994
Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5

    Topics: Animals; Brain; Chickens; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Molecular Structure; Polycyclic Compounds; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship

1997
Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors.
    Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23

    Topics: Animals; Brain; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reproducibility of Results; Sheep; Structure-Activity Relationship

1998