n-cyclopropyl adenosine-5'-carboxamide has been researched along with adenosine-5'-(n-ethylcarboxamide) in 11 studies
| Studies (n-cyclopropyl adenosine-5'-carboxamide) | Trials (n-cyclopropyl adenosine-5'-carboxamide) | Recent Studies (post-2010) (n-cyclopropyl adenosine-5'-carboxamide) | Studies (adenosine-5'-(n-ethylcarboxamide)) | Trials (adenosine-5'-(n-ethylcarboxamide)) | Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide)) |
|---|---|---|---|---|---|
| 14 | 0 | 5 | 1,333 | 4 | 133 |
| Protein | Taxonomy | n-cyclopropyl adenosine-5'-carboxamide (IC50) | adenosine-5'-(n-ethylcarboxamide) (IC50) |
|---|---|---|---|
| Adenosine receptor A3 | Homo sapiens (human) | 0.0097 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.4498 | |
| Adenosine receptor A2a | Homo sapiens (human) | 0.0336 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.0175 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0007 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0513 | |
| Adenosine receptor A1 | Gallus gallus (chicken) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Daly, JW; Kusachi, S; Olsson, RA; Padgett, W; Thompson, RD; Ukena, D | 1 |
| Daly, JW | 1 |
| Bariana, DS; Brondyk, H; Egan, RS; Fung, A; Prasad, RN; Savic, M; Stein, HH; Tietje, K | 1 |
| Fischer, B; Gallo-Rodriguez, C; Ji, XD; Melman, N; Olah, ME; Orlina, J; Pu, Q; Sanders, LH; Siegman, BD; van Galen, PJ | 1 |
| de Zwart, M; IJzerman, AP; Kooijman, H; Kourounakis, A; Link, R; Spek, AL; von Frijtag Drabbe Künzel, JK | 1 |
| Matsuda, A; Minakawa, N; Nakata, H; Saitoh, Y; Umino, T; Yoshioka, K | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Chen, VL; Gao, ZG; Ivanov, AA; Jacobson, KA; Klutz, AM; Wang, B | 1 |
| Abagyan, R; Deflorian, F; Gakh, AA; Gao, ZG; Jacobson, KA; Katritch, V; Phan, K; Stevens, RC; Tosh, DK; Xu, F | 1 |
| Auchampach, JA; Bitant, A; Ciancetta, A; Cui, Z; Gao, ZG; Gavrilova, O; Jacobson, KA; Lieberman, DI; Liu, N; Mannes, P; Mattison, JA; Rao, H; Reitman, ML; Rothwell, AC; Salmaso, V; Tosh, DK; Vaughan, KL | 1 |
| Banerjee, M; Blagg, BSJ; Brackett, CM; Gao, ZG; Jacobson, KA; Jung, YH; Tosh, DK | 1 |
1 review(s) available for n-cyclopropyl adenosine-5'-carboxamide and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
Adenosine receptors: targets for future drugs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1982 |
10 other study(ies) available for n-cyclopropyl adenosine-5'-carboxamide and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors.
Topics: Adenosine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Binding, Competitive; Biological Assay; Blood Platelets; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Coronary Circulation; Dogs; Humans; Ligands; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship | 1986 |
Modification of the 5' position of purine nucleosides. 2. Synthesis and some cardiovascular properties of adenosine-5'-(N-substituted)carboxamides.
Topics: Adenosine; Animals; Female; Hemodynamics; Lethal Dose 50; Male; Mice; Molecular Conformation; Structure-Activity Relationship | 1980 |
Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Molecular Structure; Rats; Receptors, Purinergic P1; Structure-Activity Relationship | 1994 |
5'-N-substituted carboxamidoadenosines as agonists for adenosine receptors.
Topics: Adenosine; Animals; Cell Line; Cerebral Cortex; CHO Cells; Corpus Striatum; Cricetinae; Crystallography, X-Ray; Cyclic AMP; Humans; In Vitro Techniques; Molecular Conformation; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship | 1999 |
Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins.
Topics: Adenosine; Animals; Brain; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship | 2001 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Binding Sites; Computer Simulation; Drug Design; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Receptor, Adenosine A2B; Static Electricity; Stereoisomerism | 2008 |
Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening.
Topics: Adenosine; Animals; Binding Sites; CHO Cells; Cricetinae; Drug Design; Humans; Ligands; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Monte Carlo Method; Protein Binding; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2012 |
Design and in Vivo Characterization of A
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Bridged Bicyclo Compounds; CHO Cells; Cricetulus; Drug Design; HEK293 Cells; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Molecular Structure; Receptor, Adenosine A1; Structure-Activity Relationship | 2019 |
Biological Evaluation of 5'-(
Topics: | 2021 |