n-chlorotaurine has been researched along with taurine in 207 studies
| Studies (n-chlorotaurine) | Trials (n-chlorotaurine) | Recent Studies (post-2010) (n-chlorotaurine) | Studies (taurine) | Trials (taurine) | Recent Studies (post-2010) (taurine) |
|---|---|---|---|---|---|
| 218 | 12 | 55 | 10,301 | 430 | 2,438 |
| Protein | Taxonomy | n-chlorotaurine (IC50) | taurine (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent taurine transporter | Homo sapiens (human) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (4.35) | 18.7374 |
| 1990's | 40 (19.32) | 18.2507 |
| 2000's | 94 (45.41) | 29.6817 |
| 2010's | 54 (26.09) | 24.3611 |
| 2020's | 10 (4.83) | 2.80 |
| Authors | Studies |
|---|---|
| Bozeman, PM; Learn, DB; Thomas, EL | 1 |
| Descamps-Latscha, B; Knight, J; Nguyen, AT; Witko-Sarsat, V | 1 |
| Bilzer, M; Lauterburg, BH | 1 |
| Bonner, JC; Brody, AR; Everitt, JI; Mangum, JB; Moore, LR | 1 |
| Be, RM; Gaginella, TS; Granger, DN; Grisham, MB; Tamai, H; von Ritter, C | 1 |
| Beck-Speier, I; Hinze, H; Leuschel, L; Maier, KL; Matejkova, E; Weber, H | 1 |
| Hampson, F; Shasby, DM | 1 |
| Gaull, GE; Lin, TT; Lin, YY; Sturman, JA; Wright, CE | 1 |
| Lin, YY; Nakanishi, K; Wright, CE; Zagorski, M | 1 |
| Fridovich, I; Mashino, T | 1 |
| Eckmann, CM; Roos, D; Yazdanbakhsh, M | 1 |
| Gaull, GE; Pasantes-Morales, H; Wright, CE | 1 |
| Grisham, MB; Jefferson, MM; Melton, DF; Thomas, EL | 1 |
| Gabig, TG; Lefker, BA; Ossanna, PJ; Weiss, SJ | 1 |
| Bereta, J; Grabowska, A; Marcinkiewicz, J; Stelmaszynska, T | 1 |
| Park, E; Quinn, MR; Schuller-Levis, G; Wright, C | 1 |
| Park, E; Quinn, MR; Schuller-Levis, G | 3 |
| Park, E; Quinn, MR; Schuller-Levis, G; Wright, CE | 1 |
| Hesse, D; Vogt, W | 1 |
| Beckman, JS; Crow, JP; McCord, JM | 1 |
| Ammazzalorso, M; Levis, WR; Nosrati, A; Park, E; Schuller-Levis, GB | 1 |
| Fliss, H; Tatsumi, T | 1 |
| Cantin, AM | 1 |
| Davies, JM; Davies, KJ; Horwitz, DA | 1 |
| Dunford, HB; Marquez, LA | 1 |
| Cohen, MS; Gunther, MR; Mao, J | 1 |
| Fridovich, I; Liu, ZX | 1 |
| Benov, L; Fridovich, I | 1 |
| Kim, C; Park, E; Quinn, MR; Schuller-Levis, G | 1 |
| Jia, JH; Park, E; Quinn, MR; Schuller-Levis, G | 1 |
| Winterton, N | 1 |
| Kemme, M; Saunders, D; Simon, SR; Ying, QL | 1 |
| Cunningham, C; Dixon, HB; Tipton, KF | 1 |
| Gottardi, W; Larcher, C; Nagl, M | 1 |
| Chang, YS; Chung, JK; Jeong, JM; Kim, BK; Kim, C; Kim, YJ; Koh, CS; Lee, MC; Lee, YJ | 1 |
| Alberti, J; Park, E; Quinn, MR; Schuller-Levis, G | 1 |
| McNeil, J; Shabani, F; Tippett, L | 1 |
| Daxecker, F; Gottardi, W; Miller, B; Nagl, M; Ulmer, H | 1 |
| Stanbro, WD | 1 |
| Liu, Y; Park, E; Quinn, MR; Schuller-Levis, G; Tonna-DeMasi, M | 1 |
| Chain, BM; Grabowska, A; Marcinkiewicz, J | 1 |
| Bereta, J; Bryniarski, K; Grabowska, A; Marcinkiewicz, J; Nowak, B | 1 |
| Fille, M; Gottardi, W; Nagl, M; Pfausler, B; Schmutzhard, E | 1 |
| Gottardi, W; Nagl, M | 5 |
| Gottardi, W; Hengster, P; Nagl, M; Semenitz, E | 1 |
| Liu, Y; Quinn, MR; Schuller-Levis, G | 1 |
| Bobek, M; Chain, B; Grabowska, A; Marcinkiewicz, J; Nowak, B; Petrovska, L | 1 |
| Grabowska, A; Janicka, I; Kontny, E; Kowalczewski, J; Kurowska, M; Marcinkiewicz, J; Maśliński, W | 1 |
| Gottardi, W; Nagl, M; Pöttinger, E; Teuchner, B; Ulmer, H | 1 |
| Connolly, DT; Heuvelman, DM; Hope, HR; Jennings, M; Lewis, C; Remsen, EE; Walker, MC | 1 |
| Kettle, AJ; Rothwell, LA; Vile, GF | 1 |
| Gottardi, W; Hengster, P; Hess, MW; Nagl, M; Pfaller, K | 1 |
| Janicka, I; Kontny, E; Kowalczewski, J; Kurowska, M; Marcinkiewicz, J; Maśliński, W; Szczepańska, K | 1 |
| Carr, AC; Frei, B; Hawkins, CL; Stocker, R; Thomas, SR | 1 |
| Levis, WR; Park, E; Park, SY; Quinn, MR; Schuller-Levis, GB | 1 |
| Gottardi, W; Gunkel, AR; Ichiki, H; Nagl, M; Neher, A; Schrott-Fischer, A; Stephan, K | 1 |
| Gottardi, W; Hagleitner, M; Nagl, M | 2 |
| Gottardi, W; Gunkel, A; Lass-Flörl, C; Nagl, M; Neher, A | 1 |
| Fareed, J; Jeske, WP; Kretschmer, V; Schultz, C; Stief, TW; Walenga, J | 1 |
| Barua, M; Liu, Y; Quinn, MR | 1 |
| Liu, Y; Quinn, MR | 1 |
| Jia, J; Park, E; Quinn, MR; Schuller-Levis, G | 1 |
| Inoue, J; Kanayama, A; Miyamoto, Y; Shimizu, M; Sugita-Konishi, Y | 1 |
| Borg-Von Zepelin, M; Fuchs, A; Gruber, A; Lell, CP; Lemberger, EM; Nagl, M; Würzner, R | 1 |
| Kusior, D; Olszowska, E; Olszowski, S; Szneler, E | 1 |
| Chorazy, M; Kontny, E; Marcinkiewicz, J; Maśliński, W | 1 |
| Dziewczopolski, W; Kontny, E; Maślinski, S; Maśliński, W; Rell-Bakalarska, K; Wojtecka-ŁUkasik, E | 1 |
| Biedroń, R; Bobek, M; Chain, BM; Gluszko, P; Kontny, E; Kwaśny-Krochin, B; Marcinkiewicz, J; Maśliński, W | 1 |
| Kontny, E; Kowalczewski, J; Marcinkiewicz, J; Maslinski, W; Rudnicka, W | 1 |
| Mak, P; Marcinkiewicz, J; Olszowska, E; Olszowski, S | 1 |
| Brennan, SO; Chapman, AL; Jordan, TW; Kettle, AJ; Winterbourn, CC | 1 |
| Kontny, E; Marcinkiewicz, J; Maśliński, W | 1 |
| Barua, M; Liu, Y; Quinn, MR; Serban, V | 3 |
| Liu, Y; Quinn, MR; Serban, V | 1 |
| Gottardi, W; Höpfl, R; Nagl, M; Nguyen, VA; Ulmer, H | 1 |
| Park, E; Schuller-Levis, GB | 2 |
| Marcinkiewicz, J | 2 |
| Brown, N; Miller, JM; Mitchell, A; Nagl, M; Neher, A; Prieskorn, D; Schrott-Fischer, A | 1 |
| Burakowski, T; Gujski, M; Krajewska, K; Marton, A; Maslinska, D; Maslinska, S; Wojtecka-Lukasik, E | 1 |
| Appenroth, E; Gstöttner, M; Nagl, M; Neher, A; Reisigl, F; Schindler, M; Stephan, K; Ulmer, H; Wischatta, M | 1 |
| Fuchs, D; Nagl, M; Neurauter, G; Wirleitner, B | 1 |
| Marcinkiewicz, J; Olszanecki, R | 1 |
| Elstner, E; Giese, T; McGrath, MS; Meuer, SC; Schempp, H; Stumm, S | 1 |
| Chapple, IL; Daniel, A; Mainnemare, A; Mégarbane, B; Soueidan, A | 1 |
| Emerson, DK; Knudson, CM; McCormick, ML; Schmidt, JA | 1 |
| Klamt, F; Shacter, E | 1 |
| Aoki, K; Dragosits, E; Gottardi, W; Ishiko, H; Larcher, C; Mizuki, N; Nagl, M; Ohno, S; Schidlbauer, A; Teuchner, B; Ulmer, H | 1 |
| Gujski, M; Maslinska, D; Maslinski, S; Roguska, K; Wojtecka-Lukasik, E | 1 |
| Appenroth, E; Fischer, H; Gotwald, TF; Gschwendtner, A; Gstöttner, M; Kozlov, V; Lass-Flörl, C; Mayr, A; Nagl, M; Neher, A; Ulmer, H | 1 |
| Tarkowski, A; Verdrengh, M | 1 |
| Campa, A; Catalani, LH; Kettle, AJ; Maghzal, GJ; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Bilodeau, G; Cantin, AM; Hanrahan, JW; Liao, J; Ouellet, C | 1 |
| Kim, C; Kim, JW | 1 |
| Bishop, C; Brooks, WM; Dypbukt, JM; Eriksson, H; Kettle, AJ; Thong, B | 1 |
| Peskin, AV; Winterbourn, CC | 1 |
| Hiramatsu, K; Hosako, M; Ogino, T; Okada, S; Omori, M; Ozaki, M | 1 |
| Arnitz, R; Lindner, H; Nagl, M; Neher, A; Ott, HW; Sarg, B | 1 |
| Cheah, FC; Midwinter, RG; Moskovitz, J; Vissers, MC; Winterbourn, CC | 1 |
| Choi, B; Jeon, H; Jung, Y; Kim, H; Kim, YM; Kong, H; Neckers, L; Yang, Y | 1 |
| Czuprynska, K; Gajewski, M; Gujski, M; Maslinska, D; Maslinski, S; Wojtecka-Lukasik, E | 1 |
| Fujimoto, Y; Ikeda, M; Sakuma, S | 1 |
| Arnitz, R; Gstöttner, M; Nagl, M; Neher, A; Ott, HW; Scholtz, AW | 1 |
| Gordon, YJ; Irschick, EU; Nagl, M; Romanowski, EG; Teuchner, B; Yates, KA | 1 |
| Kavanagh, K; Kelly, J; Nagl, M; O'Keeffe, J; Reeves, EP | 1 |
| Cha, YN; Choi, HS; Kim, C | 1 |
| Chorazy-Massalska, M; Kontny, E; Marcinkiewicz, J; Maśliński, W; Rudnicka, W | 2 |
| Gstöttner, M; Gunkel, AR; Nagl, M; Neher, A; Scholtz, A | 1 |
| Choi, HS; Kim, C; Kim, JW | 1 |
| Arnitz, R; Gottardi, W; Nagl, M | 1 |
| Ekremoğlu, M; Erdamar, H; Kurt, Y; Türközkan, N; Yaman, H | 1 |
| Bang, JS; Hong, SJ; Ju, SM; Jung, HS; Kim, C; Kim, KS; Lee, SH; Lee, YA; Park, EK; Yang, HI; Yoo, MC | 1 |
| Kanayama, A; Miyamoto, Y | 1 |
| Ichimura, M; Koide, N; Matsushita, K; Mizushima, T; Ochi, K; Sawa, K; Shinji, T; Shirahige, A; Tanimoto, M; Tanioka, H | 1 |
| Aspöck, H; Fürnkranz, U; Gottardi, W; Köhsler, M; Nagl, M; Walochnik, J | 1 |
| Bereta, M; Biedroń, R; Chorobik, P; Kurnyta, M; Marcinkiewicz, J; Olszanecki, R | 1 |
| Kontny, E; Marcinkiewicz, J; Maśliński, W; Muz, B | 1 |
| Kanayama, A; Miyamoto, Y; Tokunaga, S | 1 |
| Dudani, AK; Fliss, H; Martyres, A | 1 |
| Gottardi, W; Huber, J; Nagl, M; Prokop, W; Scholl-Bürgi, S; Winter, P | 1 |
| Arnitz, R; Gstöttner, M; Kröss, EM; Nagl, M; Neher, A; Schäfer, D | 1 |
| Brecx, M; Bruhn, G; Gottardi, W; Heumann, C; Hoffmann, T; Lorenz, K; Mayer, D; Nagl, M; Netuschil, L; Noack, B; Toutenburg, H | 1 |
| Gottardi, W; Nagl, M; Schmid, E; Teuchner, B; Ulmer, H | 1 |
| Chapman, AL; Davies, MJ; Kettle, AJ; Senthilmohan, R; Skaff, O | 1 |
| Cortijo, J; Martinez-Losa, M; Morcillo, EJ; Piqueras, L; Sanz, MJ | 1 |
| Biedroń, R; Bobek, M; Dulak, J; Józkowicz, A; Kontny, E; Marcinkiewicz, J; Maślinski, W; Olszanecki, R; Walczewska, M | 1 |
| Hosako, M; Ogino, T; Okada, S; Omori, M; Ozaki, M; Than, TA | 1 |
| Cha, YN; Kim, C | 2 |
| Kim, C; Kim, S | 1 |
| Aspöck, H; Fürnkranz, U; Gottardi, W; Matt, U; Nagl, M; Walochnik, J | 1 |
| Calvo, P; Crugeiras, J; Ríos, A | 1 |
| Arnitz, R; Barnickel, L; Geiger, R; Giese, T; Gottardi, W; Hauer, M; Löckinger, A; Nagl, M; Pilch, M; Pinna, A; Prossliner, H; Reinstadler, H; Scholl-Bürgi, S; Sergi, C; Steiner, HJ; Treml, B; Walther, C; Wemhöner, A | 1 |
| Choi, D; Han, J; Hong, S; Joo, K; Jung, Y; Kim, YM; Lee, Y | 1 |
| Klamt, F; Levine, RL; Pariser, A; Shacter, E; Veenstra, TD; Yu, LR; Zdanov, S; Zhang, B; Zhang, Y | 1 |
| Huemer, HP; Irschick, EU; Nagl, M | 1 |
| Chudina, NA; Murina, MA; Petrova, AO; Roshchupkin, DI; Sergienko, VI | 1 |
| Arnhold, J; Flemmig, J; Furtmüller, PG; Kirchner, T; Obinger, C | 1 |
| Agarawal, SR; Cha, YN; Cho, MR; Jang, JS; Kim, C | 1 |
| Ashby, MT; Xulu, BA | 1 |
| Carvalho, DA; Fernandes, JR; Padovan, CZ; Ximenes, VF | 1 |
| Lumassegger, M; Nagl, M; Neher, A; Pototschnig, C | 1 |
| Choi, HM; Jeong, JS; Kim, C; Kim, KS; Oh, DH; Yang, HI; Yoo, MC | 1 |
| Matsukawa, A; Ogino, T; Ozaki, M | 1 |
| Alvarez, B; Bartesaghi, S; Carballal, S; Cuevasanta, E; Denicola, A; Folkes, LK; García-Bereguiaín, MA; Gutiérrez-Merino, C; Möller, MN; Radi, R; Trujillo, M; Wardman, P | 1 |
| Aspöck, H; Duchêne, M; Fürnkranz, U; Gottardi, W; Nagl, M; Walochnik, J | 1 |
| Alvarez, N; Bassiri, M; Belisle, B; Celeri, C; Debabov, D; Khosrovi, B; Najafi, R; Payne, WG; Robson, MC; Wang, L; Xu, P | 1 |
| Cho, IS; Kim, BS; Levis, W; Park, E; Park, SY; Schuller-Levis, G | 1 |
| Cha, YN; Kim, C; Kim, KS; Wang, Y | 1 |
| Geiger, R; Giese, T; Hager, T; Hauer, M; Löckinger, A; Nagl, M; Neumeister, J; Pilch, M; Pinna, A; Pircher, I; Reinstadler, H; Schmidl, E; Scholl-Bürgi, S; Schwienbacher, M; Sergi, C; Treml, B; Willomitzer, C | 1 |
| Marcinkiewicz, J; Walczewska, M | 1 |
| Arnhold, J; Sokolov, AV; Vlasova, II | 1 |
| Anderson, M; Debabov, D; Hammerer-Lercher, A; Jekle, A; Martini, C; Nagl, M; Zuck, M | 1 |
| Holinka, J; Krepler, P; Marian, B; Pilz, M; Vavken, P | 1 |
| Anderson, M; Bechrakis, NE; Debabov, D; Eitzinger, C; Hager, T; Jekle, A; Lutz, M; Nagl, M; Schmid, E; Teuchner, B; Zuck, M | 1 |
| Anderson, M; Debabov, D; Ehrlenbach, S; Eitzinger, C; Gottardi, W; Kremser, L; Lindner, H; Nagl, M; Orth, D | 1 |
| Debabov, D; Gottardi, W; Nagl, M | 1 |
| Choi, HM; Hong, SJ; Ji, HI; Kim, C; Kim, JY; Kim, KS; Kim, SM; Lee, SH; Lee, YA; Song, R; Yang, HI; Yoo, MC | 1 |
| Kang, IS; Kim, C | 3 |
| Machul, A; Marcinkiewicz, J; Mikołajczyk, D; Strus, M; Walczewska, M | 1 |
| Andrade, MF; Azzolini, AE; Kabeya, LM; Lucisano-Valim, YM; Piatesi, F; Polizello, AC | 1 |
| Heyes, DJ; Parsons, BJ; Paterson, AW; Sibanda, S | 1 |
| Aldib, I; Colet, JM; Conotte, R; Dufrasne, F; Elfving, B; Furtmüller, PG; Gelbcke, M; Kauffmann, JM; Nève, J; Obinger, C; Podrecca, M; Prévost, M; Reye, F; Rousseau, A; Sarakbi, A; Soubhye, J; Van Antwerpen, P; Vanhaeverbeek, M; Zouaoui Boudjeltia, K | 1 |
| Cho, IS; Kascsak, RJ; Kim, BS; Park, E; Park, SY; Schuller-Levis, G; Spinner, DS | 1 |
| Friguet, B; Gareil, M; Ladouce, R; Petropoulos, I; Radjei, S; Ugarte, N | 1 |
| Chung, H; Hong, SJ; Ji, HI; Kim, C; Kim, KS; Lee, SH; Lee, YA; Yang, HI; Yoo, MC | 1 |
| Bialecka, A; Marcinkiewicz, J; Pasich, E | 1 |
| Ammann, CG; Coraça-Huber, DC; Fille, M; Hausdorfer, J; Nagl, M; Nogler, M | 2 |
| Kondrashova, KV; Murina, MA; Roshchupkin, DI; Sergienko, VI | 1 |
| Luo, S; Shacter, E; Uehara, H | 1 |
| Donskyi, IS; Kostevich, VA; Kozlov, SO; Panasenko, OM; Rudenko, AO; Sokolov, AV; Vasilyev, VB; Vlasova, II; Zakharova, ET | 1 |
| Cha, YN; Chung, HT; Jang, J; Jin, HO; Joe, Y; Kim, C; Kim, HU; Kim, K; Kim, SH; Kim, W; Lee, HN; Lee, JK; Suh, YG; Surh, YJ | 1 |
| Ciszek-Lenda, M; Jozefowski, S; Kozlowska, A; Marcinkiewicz, J; Surmiak, M; Walczewska, M | 1 |
| Binder, U; Fankhauser, H; Gönül, B; Lackner, M; Mair, C; Nagl, M; Reindl, M | 1 |
| Abu-Soud, HM; Aldhaheri, SR; Andreana, P; Jahanbakhsh, S; Jeelani, R; Khan, S; Kohan-Ghadr, HR; Morris, R; Thakur, M; Yang, Z | 1 |
| Arnitz, R; Lackner, M; Nagl, M | 1 |
| Cha, YN; Chung, HT; Joe, Y; Kim, C; Kim, K; Kim, SH; Kim, W; Suh, YG; Surh, YJ; Zhong, X | 1 |
| Cha, YN; Chung, HT; Jang, JH; Joe, Y; Kim, C; Kim, K; Kim, SH; Kim, W; Suh, YG; Surh, YJ | 1 |
| Arnitz, R; Bellmann-Weiler, R; Maass, M; Maass, V; Nagl, M; Weiss, G | 1 |
| Kavanagh, K; Nagl, M; Sheehan, G | 1 |
| Barardi, CRM; Boff, L; Garcia, LAT; Nagl, M | 1 |
| Grapsa, E; Kyriakopoulos, AM; Marcinkiewicz, J; Nagl, M | 1 |
| Nagl, M; Schaumann, P; Seifarth, C; Teuchner, B; Walochnik, J; Wibmer, ID | 1 |
| Gostner, JM; Hermann, M; Lackner, M; Leiter, H; Messner, P; Nagl, M; Rabensteiner, M; Toepfer, S | 1 |
| Baliou, S; Kyriakopoulos, AM; Spandidos, DA; Zoumpourlis, V | 1 |
| Kang, IS; Kim, C; Kim, DG; Kwon, YM | 1 |
| Dal-Pizzol, F; Dall'igna, DM; Luz, JMD; Michels, M; Vuolo, F | 1 |
| Anich, C; Lackner, M; Nagl, M; Orth-Höller, D | 1 |
| Goetz, JR; Lennon, CW; Wahl, D; Weinberger, J | 1 |
| Banki, Z; Fenner, J; Kremser, L; Lackner, M; Luttick, A; Müllauer, B; Nagl, M; Rössler, A; Sarg, B; Schwarz, C; Stadtmüller, MN; Stoiber, H; Ströhle, J; Tone, P; Volland, A; von Laer, D; Wolff, T | 1 |
| Ito, T; Murakami, S; Nguyen, KH; Schaffer, SW | 1 |
| Kang, IS; Kim, C; Kim, HJ | 1 |
| Andrieu, C; Aussel, L; Barré, R; Collet, JF; Ezraty, B; Gagnot, S; Loiseau, L; Vergnes, A | 1 |
14 review(s) available for n-chlorotaurine and taurine
| Article | Year |
|---|---|
Taurine in human nutrition: overview.
Topics: Animals; Bile Acids and Salts; Cell Membrane; Female; Humans; Inactivation, Metabolic; Milk; Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy; Taurine; Tretinoin | 1985 |
Are organochlorine compounds created in the human body?
Topics: Chlorine; Chlorohydrins; Humans; Hypochlorous Acid; Neutrophils; Taurine | 1997 |
Taurine: new implications for an old amino acid.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Antineoplastic Agents; Carboxy-Lyases; Carrier Proteins; Humans; I-kappa B Kinase; Inflammation Mediators; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; NF-kappa B; Protein Serine-Threonine Kinases; Taurine; Thiadiazines | 2003 |
Prostanoids and MPO-halide system products as a link between innate and adaptive immunity.
Topics: Animals; Humans; Immune System; Immunity, Innate; Peroxidase; Prostaglandins; Taurine | 2003 |
Taurine and its chloramine: modulators of immunity.
Topics: Animals; Carrier Proteins; Humans; Immunity; Membrane Glycoproteins; Membrane Transport Proteins; Models, Animal; Taurine | 2004 |
Hypochlorous acid and taurine-N-monochloramine in periodontal diseases.
Topics: Animals; Cytokines; Enzyme Inhibitors; Humans; Hypochlorous Acid; Inflammation Mediators; Matrix Metalloproteinase Inhibitors; NF-kappa B; Oxidation-Reduction; Periodontitis; Taurine; Transcription Factor AP-1 | 2004 |
Production of reactive oxygen and nitrogen species in phagocytes is regulated by taurine chloramine.
Topics: Animals; Carbon Monoxide; Extracellular Signal-Regulated MAP Kinases; Humans; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase Type II; Phagocytes; Phosphorylation; Protein Transport; Reactive Nitrogen Species; Reactive Oxygen Species; Taurine; Tetradecanoylphorbol Acetate | 2009 |
N-chlorotaurine, a natural antiseptic with outstanding tolerability.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Bacteria; Clinical Trials as Topic; Fungi; Humans; Parasites; Taurine; Viruses | 2010 |
Taurine bromamine (TauBr)--its role in immunity and new perspectives for clinical use.
Topics: Acne Vulgaris; Anti-Infective Agents; Anti-Inflammatory Agents; Clinical Trials as Topic; Eosinophils; Humans; Immunity, Innate; Inflammation; Neutrophils; Propionibacterium acnes; Taurine | 2010 |
[Taurine chloramine and its potential therapeutical application].
Topics: Animals; Humans; Inflammation; Inflammation Mediators; Taurine | 2011 |
N-chloramines, a promising class of well-tolerated topical anti-infectives.
Topics: Animals; Anti-Infective Agents, Local; Bacteria; Chloramines; Chlorine Compounds; Fungi; Halogenation; Humans; Hypochlorous Acid; Taurine; Viruses | 2013 |
Taurine chloramine produced from taurine under inflammation provides anti-inflammatory and cytoprotective effects.
Topics: Animals; Antioxidants; Apoptosis; Chronic Disease; Cytoprotection; Humans; Inflammation; Inflammation Mediators; Macrophage Activation; Macrophages; Neutrophil Activation; Neutrophils; Oxidoreductases; Taurine | 2014 |
N-Chlorotaurine, a Promising Future Candidate for Topical Therapy of Fungal Infections.
Topics: Administration, Inhalation; Administration, Topical; Animals; Anti-Infective Agents, Local; Humans; Mycoses; Taurine | 2018 |
Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review).
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neoplasms; Prognosis; RNA, Long Noncoding; Taurine | 2020 |
11 trial(s) available for n-chlorotaurine and taurine
| Article | Year |
|---|---|
Tolerance of N-chlorotaurine, an endogenous antimicrobial agent, in the rabbit and human eye--a phase I clinical study.
Topics: Adult; Animals; Antiviral Agents; Chi-Square Distribution; Conjunctiva; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Rabbits; Taurine | 1998 |
Tolerance of N-chlorotaurine, a new antimicrobial agent, in infectious conjunctivitis - a phase II pilot study.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Conjunctivitis, Bacterial; Conjunctivitis, Viral; Female; Gram-Positive Bacterial Infections; Haemophilus Infections; Herpes Simplex; Humans; Male; Middle Aged; Ophthalmic Solutions; Pilot Projects; Taurine; Treatment Outcome | 2000 |
Tolerability and efficacy of N-chlorotaurine in comparison with chloramine T for the treatment of chronic leg ulcers with a purulent coating: a randomized phase II study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Chloramines; Chronic Disease; Dermatologic Agents; Double-Blind Method; Drug Evaluation; Female; Humans; Leg Ulcer; Male; Middle Aged; Pain; Taurine; Tosyl Compounds; Treatment Outcome; Wound Healing | 2003 |
Acute otitis externa: efficacy and tolerability of N-chlorotaurine, a novel endogenous antiseptic agent.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Hydrocortisone; Male; Middle Aged; Neomycin; Otitis Media; Polymyxin B; Taurine | 2004 |
Tolerability and efficacy of N-chlorotaurine in epidemic keratoconjunctivitis--a double-blind, randomized, phase-2 clinical trial.
Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Aged; Anti-Bacterial Agents; Antiviral Agents; Child; Disease Outbreaks; Double-Blind Method; Enterovirus; Enterovirus Infections; Female; Gentamicins; Humans; Keratoconjunctivitis; Male; Middle Aged; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Taurine | 2005 |
Tolerability of N-chlorotaurine in chronic rhinosinusitis applied via yamik catheter.
Topics: Adult; Anti-Infective Agents; Catheterization; Chronic Disease; Female; Humans; Male; Middle Aged; Sinusitis; Spectrophotometry; Taurine; Therapeutic Irrigation | 2005 |
Comparison of taurine chloramine and taurine bromamine effects on rheumatoid arthritis synoviocytes.
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Female; Fibroblasts; Humans; Inflammation Mediators; Male; Middle Aged; Neutrophils; Synovial Membrane; Taurine | 2007 |
N-chlorotaurine--a new safe substance for postoperative ear care.
Topics: Adult; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Postoperative Complications; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Taurine; Time Factors; Tympanoplasty | 2007 |
Tolerability of N-chlorotaurine in the bovine mammary gland.
Topics: Animals; Antiviral Agents; Cattle; Female; Mammary Glands, Animal; Milk; Taurine | 2008 |
Effect of N-chlorotaurine mouth rinses on plaque regrowth and plaque vitality.
Topics: Adult; Anti-Infective Agents; Anti-Infective Agents, Local; Bacteria; Chlorhexidine; Colony Count, Microbial; Dental Plaque; Dental Plaque Index; Enzyme Inhibitors; Female; Gingival Hemorrhage; Humans; Male; Mouthwashes; Nitric Oxide Synthase; Periodontal Index; Pigmentation Disorders; Placebos; Protein Serine-Threonine Kinases; Single-Blind Method; Sodium Chloride; Taste Disorders; Taurine; Tongue Diseases; Young Adult | 2009 |
Tolerability of N-chlorotaurine plus ammonium chloride in the rabbit and human eye--a phase 1 clinical study.
Topics: Ammonium Chloride; Animals; Anti-Infective Agents, Local; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Eye; Humans; Ophthalmic Solutions; Pain; Pilot Projects; Rabbits; Taurine; Time Factors | 2008 |
182 other study(ies) available for n-chlorotaurine and taurine
| Article | Year |
|---|---|
Inhibition of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase by dapsone.
Topics: Benzidines; Bromides; Chlorides; Dapsone; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrogen-Ion Concentration; Leukocytes; Oxidation-Reduction; Peroxidase; Peroxidases; Spectrophotometry; Taurine | 1992 |
Pholasin: a new chemiluminescent probe for the detection of chloramines derived from human phagocytes.
Topics: Child; Chloramines; Firefly Luciferin; Free Radicals; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Indicators and Reagents; Luminescent Measurements; Neutrophils; Phagocytes; Taurine | 1992 |
Effects of hypochlorous acid and chloramines on vascular resistance, cell integrity, and biliary glutathione disulfide in the perfused rat liver: modulation by glutathione.
Topics: Animals; Biliary Tract; Chloramines; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Hypochlorous Acid; Liver; Male; Neutrophils; Oxides; Rats; Rats, Inbred Strains; Taurine; Vascular Resistance | 1991 |
Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins.
Topics: alpha-Macroglobulins; Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Lung; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Platelet-Derived Growth Factor; Proteins; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Serum Albumin, Bovine; Taurine | 1990 |
Effects of neutrophil-derived oxidants on intestinal permeability, electrolyte transport, and epithelial cell viability.
Topics: Animals; Body Water; Cell Membrane Permeability; Chloramines; Edetic Acid; Electrolytes; Epithelium; Hydrogen Peroxide; Hypochlorous Acid; Ileum; Inflammation; Intestinal Mucosa; Male; Neutrophils; Oxidation-Reduction; Rats; Rats, Inbred Strains; Taurine | 1990 |
Different selectivities of oxidants during oxidation of methionine residues in the alpha-1-proteinase inhibitor.
Topics: alpha 1-Antitrypsin; Animals; Blood Proteins; Chlorides; Chlorobenzoates; Hydrogen Peroxide; Methionine; Neutrophils; Oxidation-Reduction; Ozone; Pancreatic Elastase; Peroxidase; Swine; Taurine; Xanthine Oxidase | 1989 |
Effects of chlorinated amines on endothelial and epithelial barriers in vitro and ex vivo.
Topics: Albumins; Animals; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Lung; Membrane Potentials; Pulmonary Artery; Swine; Taurine | 1989 |
Taurine scavenges oxidized chlorine in biological systems.
Topics: Amino Acids; Animals; Antioxidants; Cells, Cultured; Humans; Hypochlorous Acid; Lymphocytes; Oxidation-Reduction; Taurine; Zinc | 1985 |
13C-NMR study of taurine and chlorotaurine in human cells.
Topics: Biological Transport; Cells, Cultured; Humans; In Vitro Techniques; Lymphocytes; Magnetic Resonance Spectroscopy; Taurine | 1988 |
NADPH mediates the inactivation of bovine liver catalase by monochloroamine.
Topics: Ammonium Chloride; Animals; Aspergillus niger; Catalase; Cattle; Chloramines; Liver; NADP; Spectrophotometry; Taurine | 1988 |
Killing of schistosomula by taurine chloramine and taurine bromamine.
Topics: Animals; Dose-Response Relationship, Drug; Schistosoma mansoni; Taurine | 1987 |
Evidence for a role of taurine in the in vitro oxidative toxicity of neutrophils toward erythrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Chloromercuribenzoates; Erythrocytes; Glutathione; Humans; NADP; Neutrophils; Oxidation-Reduction; Oxyhemoglobins; p-Chloromercuribenzoic Acid; Taurine | 1985 |
Proton stoichiometry associated with human neutrophil respiratory-burst reactions.
Topics: Cell Fractionation; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Taurine | 1984 |
Taurine chloramine, a product of activated neutrophils, inhibits in vitro the generation of nitric oxide and other macrophage inflammatory mediators.
Topics: Animals; Cells, Cultured; Cytokines; Dinoprostone; Inflammation Mediators; Macrophages; Male; Mice; Mice, Inbred CBA; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Taurine | 1995 |
Taurine protects against oxidant-induced lung injury: possible mechanism(s) of action.
Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Female; Kinetics; Lung Diseases; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Ozone; Rats; Rats, Sprague-Dawley; Taurine; Tumor Necrosis Factor-alpha | 1994 |
Taurine chloramine inhibits production of nitric oxide and TNF-alpha in activated RAW 264.7 cells by mechanisms that involve transcriptional and translational events.
Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Blotting, Western; Cell Line; Mice; Nitric Oxide; Nitric Oxide Synthase; Protein Biosynthesis; Taurine; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1995 |
Taurine chloramine inhibits the synthesis of nitric oxide and the release of tumor necrosis factor in activated RAW 264.7 cells.
Topics: Amino Acid Oxidoreductases; Animals; Biological Transport; Cell Line; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Mice; Nitric Oxide; Nitric Oxide Synthase; Recombinant Proteins; Taurine; Tumor Necrosis Factor-alpha | 1993 |
Oxidants generated by the myeloperoxidase-halide system activate the fifth component of human complement, C5.
Topics: Complement Activation; Complement C5; Electrophoresis, Polyacrylamide Gel; Humans; Hypochlorous Acid; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Taurine | 1994 |
Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite.
Topics: Alcohol Dehydrogenase; Cysteine; Histidine; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Molsidomine; Nitrates; Sulfhydryl Compounds; Taurine; Zinc | 1995 |
Mycobacterial lipoarabinomannan induces nitric oxide and tumor necrosis factor alpha production in a macrophage cell line: down regulation by taurine chloramine.
Topics: Animals; Cell Line; Down-Regulation; Female; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Mycobacterium; Nitric Oxide; Recombinant Proteins; Taurine; Tumor Necrosis Factor-alpha | 1994 |
Hypochlorous acid and chloramines increase endothelial permeability: possible involvement of cellular zinc.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chloramines; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypochlorous Acid; In Vitro Techniques; Lung; Male; Microcirculation; Perfusion; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; Taurine; Thiones; Zinc | 1994 |
Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Animals; Anions; Bronchitis; Cats; Cell Line; Cystic Fibrosis; Dimethyl Sulfoxide; Epithelium; Female; Humans; Hypochlorous Acid; Lung; Male; Reference Values; Smoking; Taurine; Temperature | 1994 |
Inhibition of collagenase activity by N-chlorotaurine, a product of activated neutrophils.
Topics: Animals; Cattle; Collagen; Hypochlorous Acid; Matrix Metalloproteinase Inhibitors; Neutrophils; Taurine | 1994 |
Chlorination of taurine by myeloperoxidase. Kinetic evidence for an enzyme-bound intermediate.
Topics: Animals; Cattle; Chlorides; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Mathematics; Models, Theoretical; Peroxidase; Protein Binding; Spleen; Taurine | 1994 |
Oxidant-scavenging activities of ampicillin and sulbactam and their effects on neutrophil functions.
Topics: Ampicillin; Blood Bactericidal Activity; Free Radical Scavengers; Humans; Luminescent Measurements; Neutrophils; Oxidants; Peroxidase; Sodium Hypochlorite; Sulbactam; Taurine; Zymosan | 1993 |
Negative chemotaxis in Cytophaga johnsonae.
Topics: Chemotaxis; Cytophaga; Hydrogen Peroxide; Hydrogen-Ion Concentration; Nalidixic Acid; Sodium Hypochlorite; Taurine | 1996 |
Escherichia coli exhibits negative chemotaxis in gradients of hydrogen peroxide, hypochlorite, and N-chlorotaurine: products of the respiratory burst of phagocytic cells.
Topics: Animals; Chemotaxis; Escherichia coli; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Mutation; Phagocytes; Respiratory Burst; Taurine | 1996 |
Taurine chloramine inhibits prostaglandin E2 production in activated RAW 264.7 cells by post-transcriptional effects on inducible cyclooxygenase expression.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Isoenzymes; Macrophage Activation; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Taurine | 1996 |
The production of superoxide anion and nitric oxide by cultured murine leukocytes and the accumulation of TNF-alpha in the conditioned media is inhibited by taurine chloramine.
Topics: Animals; Cells, Cultured; Culture Media, Conditioned; Female; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Neutrophils; Nitric Oxide; Nitrites; Superoxides; Taurine; Tumor Necrosis Factor-alpha | 1996 |
Preactivation exposure of RAW 264.7 cells to taurine chloramine attenuates subsequent production of nitric oxide and expression of iNOS mRNA.
Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Inflammation Mediators; Macrophage Activation; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Taurine | 1997 |
Glycosaminoglycans regulate elastase inhibition by oxidized secretory leukoprotease inhibitor.
Topics: Glycosaminoglycans; Heparin; Humans; Inflammation; Kinetics; Leukocyte Elastase; Oxidation-Reduction; Proteinase Inhibitory Proteins, Secretory; Proteins; Recombinant Proteins; Secretory Leukocyte Peptidase Inhibitor; Serine Proteinase Inhibitors; Taurine | 1997 |
Conversion of taurine into N-chlorotaurine (taurine chloramine) and sulphoacetaldehyde in response to oxidative stress.
Topics: Acetaldehyde; Animals; Catalysis; Chlorine; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Luminescent Measurements; Neutrophils; Oxidative Stress; Rats; Respiratory Burst; Spectrometry, Fluorescence; Taurine | 1998 |
Activity of N-chlorotaurine against herpes simplex- and adenoviruses.
Topics: Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; HeLa Cells; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Taurine; Vero Cells | 1998 |
Uptake of taurine and taurine chloramine in murine macrophages and their distribution in mice with experimental inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Humans; Inflammation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Taurine; Turpentine | 1998 |
Taurine chloramine inhibits the production of superoxide anion, IL-6 and IL-8 in activated human polymorphonuclear leukocytes.
Topics: Animals; Cells, Cultured; Chloramines; Female; Humans; Interleukin-6; Interleukin-8; Mice; Mice, Inbred BALB C; Neutrophils; Rats; Rats, Sprague-Dawley; Superoxides; Taurine | 1998 |
The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.
Topics: Animals; Antioxidants; Antirheumatic Agents; Auranofin; Aurothioglucose; Cell Line; Chlorocebus aethiops; Chloroquine; Collagenases; Gold Sodium Thiomalate; Humans; Hypochlorous Acid; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Methotrexate; Neutrophils; Oxidants; Oxidation-Reduction; Penicillamine; Peptide Fragments; Peroxidase; Recombinant Fusion Proteins; Respiratory Burst; Structure-Activity Relationship; Taurine; Tissue Inhibitor of Metalloproteinase-1 | 1998 |
A kinetic model of the myeloperoxidase-hydrogen peroxide-chloride ion system in phagolysosomes.
Topics: Animals; Chlorides; Hydrogen Peroxide; Mammals; Models, Biological; Neutrophils; Oxidative Stress; Peroxidase; Peroxides; Phagosomes; Taurine; Tyrosine | 1998 |
Taurine chloramine inhibits production of nitric oxide and prostaglandin E2 in activated C6 glioma cells by suppressing inducible nitric oxide synthase and cyclooxygenase-2 expression.
Topics: Animals; Blotting, Northern; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Humans; Inflammation Mediators; Isoenzymes; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Taurine; Tumor Cells, Cultured | 1998 |
Modulation of antigen-specific T-cell activation in vitro by taurine chloramine.
Topics: Animals; Antigen-Presenting Cells; Antigens; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Hybridomas; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA; Ovalbumin; T-Lymphocytes; Taurine | 1998 |
Taurine chloramine down-regulates the generation of murine neutrophil inflammatory mediators.
Topics: Animals; Cells, Cultured; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Eicosanoids; Inflammation Mediators; Interleukin-6; Luminescent Measurements; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Nitric Oxide; Superoxides; Taurine; Tumor Necrosis Factor-alpha | 1998 |
Tolerance and bactericidal action of N-chlorotaurine in a urinary tract infection by an omniresistant Pseudomonas aeruginosa.
Topics: Adult; Anti-Bacterial Agents; Cystitis; Drug Tolerance; Humans; Male; Pseudomonas Infections; Taurine; Treatment Outcome; Urinary Tract Infections | 1998 |
Rapid killing of Mycobacterium terrae by N-chlorotaurine in the presence of ammonium is caused by the reaction product monochloramine.
Topics: Ammonium Chloride; Chloramines; Dose-Response Relationship, Drug; Drug Synergism; Nontuberculous Mycobacteria; Taurine; Time Factors | 1998 |
The postantibiotic effect of N-chlorotaurine on Staphylococcus aureus. Application in the mouse peritonitis model.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Disease Models, Animal; Mice; Peritonitis; Staphylococcal Infections; Staphylococcus aureus; Taurine | 1999 |
Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 production is inhibited by taurine chloramine in rat C6 glioma cells.
Topics: Animals; Chemokine CCL4; Chemokine CXCL2; Glioma; Inflammation Mediators; Macrophage Inflammatory Proteins; Monokines; Neuroglia; Rats; RNA, Messenger; Taurine; Tumor Cells, Cultured | 1999 |
Regulation of murine dendritic cell functions in vitro by taurine chloramine, a major product of the neutrophil myeloperoxidase-halide system.
Topics: Animals; Cell Survival; Cells, Cultured; Cytokines; Dendritic Cells; Dose-Response Relationship, Drug; Flow Cytometry; Interferon-gamma; Interleukin-10; Interleukin-2; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Nitrites; Superoxides; T-Lymphocytes; Taurine | 1999 |
Taurine chloramine inhibition of cell proliferation and cytokine production by rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Division; Female; Fibroblasts; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Male; Middle Aged; Synovial Membrane; Taurine; Time Factors | 1999 |
Large-scale purification of myeloperoxidase from HL60 promyelocytic cells: characterization and comparison to human neutrophil myeloperoxidase.
Topics: Benzidines; Blotting, Western; Chromatography, Gel; Dapsone; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme Stability; HL-60 Cells; Humans; Molecular Weight; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Denaturation; Taurine; Ultracentrifugation | 2000 |
Initiation of rapid, P53-dependent growth arrest in cultured human skin fibroblasts by reactive chlorine species.
Topics: Cell Division; Cell Survival; Cells, Cultured; Chloramines; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Dose-Response Relationship, Drug; Fibroblasts; Glycine; Humans; Hypochlorous Acid; Inflammation; Inflammation Mediators; Skin; Taurine; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53 | 2000 |
Bactericidal activity of micromolar N-chlorotaurine: evidence for its antimicrobial function in the human defense system.
Topics: Adult; Anti-Bacterial Agents; Chloramines; Granulocytes; Half-Life; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Microbial Sensitivity Tests; Microscopy, Electron; Oxidants; Staphylococcus aureus; Taurine | 2000 |
The mechanism of taurine chloramine inhibition of cytokine (interleukin-6, interleukin-8) production by rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Aged; Arthritis, Rheumatoid; DNA-Binding Proteins; Female; Fibroblasts; Host Cell Factor C1; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Male; Middle Aged; NF-kappa B; Octamer Transcription Factor-1; Synovial Membrane; Taurine; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic | 2000 |
Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents.
Topics: alpha 1-Antitrypsin; Ascorbic Acid; Chloramines; Female; Free Radicals; Humans; Hypochlorous Acid; In Vitro Techniques; Male; Methionine; Oxidants; Serum Albumin; Sulfhydryl Compounds; Taurine | 2001 |
Regulation of nitric oxide induced by mycobacterial lipoarabinomannan in murine macrophages: effects of interferon-beta and taurine-chloramine.
Topics: Animals; Dose-Response Relationship, Drug; Female; Inflammation Mediators; Interferon Type I; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Mycobacterium; Nitric Oxide; Recombinant Proteins; Taurine | 2000 |
N-chlorotaurine, a novel endogenous antimicrobial agent: tolerability testing in a mouse model.
Topics: Animals; Anti-Infective Agents; Drug Tolerance; Ear, Inner; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Injections; Male; Mice; Mice, Inbred BALB C; Sodium Chloride; Taurine; Trimethyltin Compounds | 2001 |
The influence of plasma on the disinfecting activity of the new antimicrobial agent N-chlorotaurine-sodium in comparison with chloramine T.
Topics: Animals; Antiviral Agents; Bacteria; Cattle; Chloramines; Disinfectants; Halogens; Humans; Microbial Sensitivity Tests; Oxidation-Reduction; Plasma; Taurine; Tosyl Compounds | 2001 |
Enhanced fungicidal activity of N-chlorotaurine in nasal secretion.
Topics: Antifungal Agents; Aspergillus; Candida; Fusarium; Humans; Microbial Sensitivity Tests; Nasal Mucosa; Penicillium; Quaternary Ammonium Compounds; Taurine | 2001 |
Singlet oxygen inhibits agonist-induced P-selectin expression and formation of platelet aggregates.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chloramines; Collagen; Depression, Chemical; Free Radical Scavengers; Gene Expression Regulation; Hemostasis; Humans; Macaca mulatta; Mannitol; Methionine; Neutrophils; Oxidants; Oxidation-Reduction; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteins; Receptors, Thrombin; Respiratory Burst; Singlet Oxygen; Taurine; Tosyl Compounds | 2001 |
Taurine chloramine inhibits inducible nitric oxide synthase and TNF-alpha gene expression in activated alveolar macrophages: decreased NF-kappaB activation and IkappaB kinase activity.
Topics: Animals; Cell Line; Cells, Cultured; Clone Cells; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; I-kappa B Kinase; Immunosuppressive Agents; Inflammation Mediators; Macrophage Activation; Macrophages, Alveolar; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Taurine; Tumor Necrosis Factor-alpha | 2001 |
Chemokine production by rat alveolar macrophages is inhibited by taurine chloramine.
Topics: Animals; Cell Line; Chemokine CCL2; Chemokine CXCL2; Chemokines; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Inflammation Mediators; Macrophages, Alveolar; NF-kappa B; Rats; RNA, Messenger; Taurine; Time Factors | 2002 |
Taurine chloramine attenuates the hydrolytic activity of matrix metalloproteinase-9 in LPS-activated murine peritoneal macrophages.
Topics: Animals; Cells, Cultured; Edetic Acid; Enzyme Inhibitors; Female; Hydrolysis; Inflammation Mediators; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mitogens; Nitrites; Taurine | 2000 |
Taurine chloramine inhibits lymphocyte proliferation and decreases cytokine production in activated human leukocytes.
Topics: Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-2; Interleukin-6; Interleukin-8; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Taurine | 2002 |
Oxidation of Ikappa Balpha at methionine 45 is one cause of taurine chloramine-induced inhibition of NF-kappa B activation.
Topics: Amino Acid Substitution; Cell Line; Chromatography, High Pressure Liquid; DNA-Binding Proteins; Enzyme Inhibitors; Genes, Reporter; Humans; I-kappa B Proteins; Interleukin-8; Jurkat Cells; Kinetics; Luciferases; Mass Spectrometry; Methionine; Mutagenesis, Site-Directed; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotide Probes; Oxidation-Reduction; Recombinant Proteins; Taurine | 2002 |
Impact of N-chlorotaurine on viability and production of secreted aspartyl proteinases of Candida spp.
Topics: Aspartic Acid Endopeptidases; Candida; Microbial Sensitivity Tests; Protease Inhibitors; Taurine | 2002 |
Sulphoacetaldehyde as a product of taurine chloramine peroxidation at site of inflammation.
Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Horseradish Peroxidase; Hydrogen Peroxide; Inflammation; Oxidation-Reduction; Taurine | 2002 |
Taurine chloramine modulates cytokine production by human peripheral blood mononuclear cells.
Topics: Adult; Female; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Middle Aged; Taurine; Tumor Necrosis Factor-alpha | 2002 |
Impaired generation of taurine chloramine by synovial fluid neutrophils of rheumatoid arthritis patients.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Luminescent Measurements; Male; Middle Aged; Neutrophils; Respiratory Burst; Synovial Fluid; Taurine; Zymosan | 2002 |
Effect of taurine chloramine, the product of activated neutrophils, on the development of collagen-induced arthritis in DBA 1/J mice.
Topics: Animals; Arthritis, Experimental; Collagen; Interleukin-6; Macrophages, Peritoneal; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neutrophil Activation; Neutrophils; Nitric Oxide; Peroxidase; Taurine; Tumor Necrosis Factor-alpha | 2002 |
Chemical properties of N-chlorotaurine sodium, a key compound in the human defence system.
Topics: Disinfectants; Drug Stability; Humans; Hydrogen-Ion Concentration; Hydrolysis; Inflammation Mediators; Kinetics; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Taurine | 2002 |
Selective inhibition of cyclooxygenase 2-generated prostaglandin E2 synthesis in rheumatoid arthritis synoviocytes by taurine chloramine.
Topics: Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Humans; Interleukin-1; Isoenzymes; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Synovial Membrane; Taurine | 2003 |
Collagen type II modification by hypochlorite.
Topics: Amino Acids; Animals; Antigen-Antibody Complex; Cartilage; Chickens; Chlorine; Circular Dichroism; Collagen Type II; Enzyme-Linked Immunosorbent Assay; Hypochlorous Acid; Inflammation Mediators; Oxidation-Reduction; Protein Structure, Secondary; Quaternary Ammonium Compounds; Taurine; Tyrosine | 2003 |
Characterization of non-covalent oligomers of proteins treated with hypochlorous acid.
Topics: Amino Acids; Animals; Apoproteins; Chloramines; Dimerization; Hemoglobins; Humans; Hypochlorous Acid; Kinetics; Myoglobin; Oxidants; Proteins; Spectrometry, Mass, Electrospray Ionization; Succinates; Taurine | 2003 |
Anti-inflammatory activities of taurine chloramine: implication for immunoregulation and pathogenesis of rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Inflammation; Mice; Taurine | 2003 |
Taurine chloramine inhibits production of inflammatory mediators and iNOS gene expression in alveolar macrophages; a tale of two pathways: part I, NF-kappaB signaling.
Topics: Animals; Cell Line; Gene Expression Regulation, Enzymologic; Inflammation Mediators; Macrophages, Alveolar; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Rats; Signal Transduction; Taurine | 2003 |
Taurine chloramine inhibits production of inflammatory mediators and iNOS gene expression in alveolar macrophages; a tale of two pathways: part II, IFN-gamma signaling through JAK/Stat.
Topics: Animals; Base Sequence; Cell Line; DNA Probes; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Inflammation Mediators; Interferon-gamma; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Signal Transduction; Taurine; Trans-Activators | 2003 |
Production of nitric oxide by activated microglial cells is inhibited by taurine chloramine.
Topics: Animals; Blotting, Northern; Cell Line; Mice; Microglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Taurine | 2003 |
Production of inflammatory mediators by activated C6 cells is attenuated by taurine chloramine inhibition of NF-kappaB activation.
Topics: Animals; Base Sequence; Cell Line, Tumor; DNA Primers; Inflammation Mediators; NF-kappa B; Rats; Taurine | 2003 |
Tolerability of N-chlorotaurine in the guinea pig middle ear: a pilot study using an improved application system.
Topics: Animals; Anti-Infective Agents; Drug Delivery Systems; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Taurine | 2004 |
Taurine chloramine modifies carrageenin- and casein-induced inflammation in the rat.
Topics: Animals; Carrageenan; Caseins; Inflammation; Inflammation Mediators; Male; Neutrophils; Rats; Rats, Wistar; Taurine | 2004 |
Down-regulatory effect of N-chlorotaurine on tryptophan degradation and neopterin production in human PBMC.
Topics: Cell Survival; Concanavalin A; Down-Regulation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Taurine; Tryptophan; Tryptophan Oxygenase | 2004 |
Taurine chloramine and taurine bromamine induce heme oxygenase-1 in resting and LPS-stimulated J774.2 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Taurine; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Differential effects on innate versus adaptive immune responses by WF10.
Topics: Chlorine; Cytokines; DNA-Binding Proteins; Humans; Immunity, Cellular; Immunity, Innate; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Oxidants; Oxides; T-Lymphocytes; Taurine; Transcription Factor AP-1; Transcription Factors | 2004 |
Taurine monochloramine activates a cell death pathway involving Bax and Caspase-9.
Topics: Animals; B-Lymphocytes; bcl-2-Associated X Protein; Caspase 9; Caspases; Cell Death; Cell Division; Cell Line; Cell Survival; Clone Cells; Inflammation Mediators; Mice; Proto-Oncogene Proteins c-bcl-2; Taurine | 2005 |
Chlorine covers on living bacteria: the initial step in antimicrobial action of active chlorine compounds.
Topics: Bacteria; Chloramines; Chlorine; Chlorine Compounds; Disinfectants; Models, Molecular; Molecular Structure; Oxidation-Reduction; Surface Properties; Taurine; Time Factors; Tosyl Compounds; Triazines | 2005 |
Taurine chloramine, an oxidant derived from neutrophils, induces apoptosis in human B lymphoma cells through mitochondrial damage.
Topics: Anti-Bacterial Agents; Apoptosis; Bongkrekic Acid; Caspase 9; Caspases; Cell Death; Cell Line, Tumor; Cyclosporine; Enzyme Inhibitors; Humans; Indicators and Reagents; Inflammation Mediators; Intracellular Membranes; Lymphoma, B-Cell; Membrane Potentials; Microscopy, Confocal; Mitochondria; Neutrophils; Oxidants; Oxygen; Permeability; Propidium; Sulfhydryl Compounds; Taurine; Time Factors; Valinomycin | 2005 |
Taurine chloramine modifies adjuvant arthritis in rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; beta-N-Acetylhexosaminidases; Histamine; Male; Rats; Rats, Inbred BN; Taurine | 2005 |
Inhibition of septic arthritis by local administration of taurine chloramine, a product of activated neutrophils.
Topics: Animals; Arthritis, Infectious; Cells, Cultured; Disease Models, Animal; Down-Regulation; Female; Inflammation Mediators; Injections, Intra-Articular; Interleukin-6; Lymphocytes; Methicillin Resistance; Mice; Mice, Inbred Strains; Neutrophils; Spleen; Staphylococcal Infections; Staphylococcus aureus; Taurine | 2005 |
Superoxide-dependent oxidation of melatonin by myeloperoxidase.
Topics: Animals; Antioxidants; Catalase; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kynuramine; Liver; Mass Spectrometry; Melatonin; Models, Chemical; Neutrophils; Oxygen; Ozone; Peroxidase; Protein Binding; Superoxides; Taurine; Time Factors; Xanthine Oxidase | 2005 |
Oxidant stress suppresses CFTR expression.
Topics: Adenocarcinoma; Antioxidants; Cell Line, Tumor; Colonic Neoplasms; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Interactions; Epithelial Cells; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; Hydroquinones; Iodine Radioisotopes; Mucins; Oxidants; Oxidative Stress; RNA, Messenger; Taurine | 2006 |
Inhibition of LPS-induced NO production by taurine chloramine in macrophages is mediated though Ras-ERK-NF-kappaB.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytoprotection; DNA; Extracellular Signal-Regulated MAP Kinases; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; ras Proteins; Signal Transduction; Taurine; Transcription Factor AP-1 | 2005 |
N,N-dichlorotaurine: chemical and bactericidal properties.
Topics: Anti-Infective Agents, Local; Bacteria; Buffers; Chloramines; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Potassium; Proteus mirabilis; Sodium; Solutions; Spectrophotometry; Staphylococcus aureus; Taurine; Temperature | 2005 |
A sensitive and selective assay for chloramine production by myeloperoxidase.
Topics: Benzidines; Bromides; Chloramines; Humans; Hypochlorous Acid; Iodides; Neutrophils; Peroxidase; Rhodamines; Sensitivity and Specificity; Taurine | 2005 |
Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Binding, Competitive; Creatine Kinase; Cysteine; Disulfides; Enzyme Inhibitors; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypochlorous Acid; Methionine; Muscles; Oxidants; Oxidation-Reduction; Rabbits; Sulfhydryl Compounds; Taurine | 2006 |
Oxidative modification of IkappaB by monochloramine inhibits tumor necrosis factor alpha-induced NF-kappaB activation.
Topics: Chloramines; Humans; I-kappa B Kinase; I-kappa B Proteins; In Vitro Techniques; Jurkat Cells; Methionine; NF-kappa B; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Taurine; Tumor Necrosis Factor-alpha | 2005 |
Protein sites of attack of N-chlorotaurine in Escherichia coli.
Topics: Acyl-Carrier Protein S-Malonyltransferase; Bacterial Proteins; Chaperonin 60; Cysteine; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Escherichia coli; Oxidation-Reduction; Periplasmic Binding Proteins; Protein Serine-Threonine Kinases; Proteomics; Ribosomal Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfonic Acids; Taurine | 2006 |
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.
Topics: Active Transport, Cell Nucleus; Antioxidants; Cell Membrane Permeability; Chloramines; Glutathione; Glycine; Humans; Hypochlorous Acid; I-kappa B Proteins; Jurkat Cells; Methionine; Neoplasm Proteins; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidants; Oxidation-Reduction; Taurine; Tumor Necrosis Factor-alpha | 2006 |
A molecular mechanism for the anti-inflammatory effect of taurine-conjugated 5-aminosalicylic acid in inflamed colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chromatography, High Pressure Liquid; Colitis; Colon; Dose-Response Relationship, Drug; Humans; Mesalamine; NF-kappa B; Phosphorylation; Rats; Serine; Taurine; Tumor Necrosis Factor-alpha | 2006 |
Taurine-chloramine is a potent antiinflammatory substance.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Histamine; Inflammation; Male; Rats; Reactive Oxygen Species; Taurine | 2006 |
Monochloramine potently inhibits arachidonic acid metabolism in rat platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Blood Platelets; Chloramines; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glutamine; Hypochlorous Acid; Lipoxygenase Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Taurine; Thromboxane B2 | 2006 |
A novel N-chlorotaurine-corticosteroid combination as a preservative-free local disinfectant: influence on the ciliary beat frequency in vitro.
Topics: Androstadienes; Anti-Infective Agents, Local; Cells, Cultured; Cilia; Disinfectants; Dose-Response Relationship, Drug; Drug Combinations; Fluticasone; Humans; In Vitro Techniques; Maximum Tolerated Dose; Mucociliary Clearance; Nasal Mucosa; Sensitivity and Specificity; Taurine | 2006 |
N-chlorotaurine is an effective antiviral agent against adenovirus in vitro and in the Ad5/NZW rabbit ocular model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Infections, Viral; Female; Keratitis; Ophthalmic Solutions; Organophosphonates; Rabbits; Taurine; Viral Plaque Assay; Virus Replication | 2006 |
Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Gliotoxin; Humans; Microbial Sensitivity Tests; Quaternary Ammonium Compounds; Taurine | 2006 |
Taurine chloramine inhibits PMA-stimulated superoxide production in human neutrophils perhaps by inhibiting phosphorylation and translocation of p47(phox).
Topics: Cell Line, Transformed; Cell Line, Tumor; Enzyme Inhibitors; Humans; NADPH Oxidases; Neutrophils; Phosphorylation; Protein Transport; Superoxides; Taurine; Tetradecanoylphorbol Acetate | 2006 |
Taurine chloramine inhibits proliferation of rheumatoid arthritis synoviocytes by triggering a p53-dependent pathway.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Female; Humans; Inhibitor of Apoptosis Proteins; Knee; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Proliferating Cell Nuclear Antigen; RNA, Messenger; Survivin; Synovial Membrane; Taurine; Tumor Suppressor Protein p53 | 2006 |
Taurine chloramine inhibits the production of nitric oxide and superoxide anion by modulating specific mitogen-activated protein kinases.
Topics: Animals; Cell Line; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Macrophages; Mice; Nitric Oxide; Oxidants; p38 Mitogen-Activated Protein Kinases; Superoxides; Taurine; Tetradecanoylphorbol Acetate | 2006 |
N-Chlorotaurine and ammonium chloride: an antiseptic preparation with strong bactericidal activity.
Topics: Ammonium Chloride; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacteria; Chemistry, Pharmaceutical; Chloramines; Drug Combinations; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Taurine; Time Factors; Water | 2007 |
The effect of taurine on polymorphonuclear leukocyte functions in endotoxemia.
Topics: Animals; Endotoxemia; Endotoxins; Guinea Pigs; Male; Neutrophils; Nitric Oxide; Peroxidase; Random Allocation; Taurine | 2007 |
Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta stimulated fibroblast-like synoviocytes.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Interleukin-1beta; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Signal Transduction; Synovial Membrane; Taurine | 2007 |
Apoptosis triggered by phagocytosis-related oxidative stress through FLIPS down-regulation and JNK activation.
Topics: Antiviral Agents; Apoptosis; Blotting, Western; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cell Survival; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kidney; MAP Kinase Kinase Kinase 5; Neutrophils; NF-kappa B; Oxidative Stress; Peroxidase; Phagocytosis; Protein Serine-Threonine Kinases; Taurine; Tumor Necrosis Factor-alpha | 2007 |
Oral administration of taurine improves experimental pancreatic fibrosis.
Topics: Administration, Oral; Animals; Collagen Type I; Diet; Enzyme Inhibitors; Fibrosis; Interleukin-2; Interleukin-6; Male; Matrix Metalloproteinase Inhibitors; Organotin Compounds; Pancreas; Pancreatitis; Rats; Rats, Wistar; Taurine; Transforming Growth Factor beta1; Up-Regulation | 2008 |
Cytotoxic activity of N-chlorotaurine on Acanthamoeba spp.
Topics: Acanthamoeba; Ammonium Chloride; Animals; Anti-Infective Agents, Local; Antiprotozoal Agents; beta-Alanine; Humans; Hydrogen-Ion Concentration; Parasitic Sensitivity Tests; Taurine | 2008 |
The role of heme oxygenase-1 in down regulation of PGE2 production by taurine chloramine and taurine bromamine in J774.2 macrophages.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Heme Oxygenase-1; Macrophages; Mice; Mitogen-Activated Protein Kinase Kinases; Nitric Oxide Synthase Type II; Taurine | 2008 |
Heme oxygenase-1 participates in the anti-inflammatory activity of taurine chloramine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Heme Oxygenase-1; Hemin; Humans; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Structure-Activity Relationship; Taurine | 2008 |
Modification of IkappaBalpha by taurine bromamine inhibits tumor necrosis factor alpha-induced NF-kappaB activation.
Topics: Cell Membrane Permeability; Eosinophils; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; I-kappa B Kinase; Jurkat Cells; NF-kappa B; Oxidation-Reduction; T-Lymphocytes; Taurine; Thiocyanates; Tumor Necrosis Factor-alpha | 2007 |
Short communication: rapid preparation of preventive and therapeutic whole-killed retroviral vaccines using the microbicide taurine chloramine.
Topics: AIDS Vaccines; Animals; Antiviral Agents; Female; HIV Infections; HIV-1; Humans; Immunization Schedule; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Spleen; Taurine; Vaccination; Virus Inactivation; Virus Replication | 2008 |
Antimicrobial activity of dexamethasone and its combination with N-chlorotaurine.
Topics: Anti-Infective Agents; Aspergillus flavus; Aspergillus fumigatus; Bacteria; Dexamethasone; Drug Therapy, Combination; Fungi; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus milleri Group; Taurine | 2008 |
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide.
Topics: Bromates; Bromides; Humans; Neutrophils; Phenylacetates; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase; Superoxides; Taurine | 2009 |
Taurine chloramine inhibits functional responses of human eosinophils in vitro.
Topics: Apoptosis; Calcium; Cells, Cultured; Enzyme Inhibitors; Eosinophil Cationic Protein; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-5; Leukotriene C4; NADPH Oxidases; NF-kappa B; Peroxidase; Phosphoproteins; Respiratory Burst; Superoxides; Taurine | 2009 |
Taurine haloamines and heme oxygenase-1 cooperate in the regulation of inflammation and attenuation of oxidative stress.
Topics: Animals; Carbon Monoxide; Cytokines; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Taurine | 2009 |
Taurine chloramine: a possible oxidant reservoir.
Topics: Ammonium Chloride; Animals; Cell Membrane Permeability; Cells, Cultured; Neutrophils; Oxidants; Rats; Taurine | 2009 |
Taurine chloramine inhibits LPS-induced glucose uptake and glucose transporter 1 expression in RAW 264.7 macropages.
Topics: Animals; Cell Line; Glucose; Glucose Transporter Type 1; Humans; Lipopolysaccharides; Macrophages; Mice; Taurine | 2009 |
N-Chlorotaurine shows high in vitro activity against promastigotes and amastigotes of Leishmania species.
Topics: Ammonium Chloride; Animals; Antiprotozoal Agents; Cell Line; Drug Synergism; Humans; In Vitro Techniques; Leishmania; Leishmania donovani; Leishmania infantum; Macrophages; Monocytes; Parasitic Sensitivity Tests; Taurine | 2009 |
Kinetic and thermodynamic barriers to chlorine transfer between amines in aqueous solution.
Topics: Benzylamines; Chlorine; Dimethylamines; Kinetics; Phase Transition; Solutions; Taurine; Thermodynamics; Water | 2009 |
Tolerability of inhaled N-chlorotaurine in the pig model.
Topics: Administration, Inhalation; Ammonium Chloride; Animals; Anti-Infective Agents, Local; Blood Pressure; Exhalation; Models, Animal; Respiratory Mechanics; Respiratory Mucosa; Swine; Taurine; Tidal Volume | 2009 |
An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Colitis; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; I-kappa B Kinase; Interleukin-1beta; Mesalamine; NF-kappa B; Prodrugs; Taurine | 2009 |
Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin.
Topics: Alanine; Amino Acid Substitution; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Chlorocebus aethiops; Cofilin 1; COS Cells; Cysteine; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Humans; Hydrogen Peroxide; Mitochondria, Liver; Oxidants; Oxidation-Reduction; Plasmids; Rats; Recombinant Proteins; RNA, Small Interfering; Subcellular Fractions; Taurine; Time Factors; Transfection | 2009 |
In vitro prevention of vaccinia and herpesvirus infection spread in explanted human corneas by N-chlorotaurine.
Topics: Antiviral Agents; Cornea; Cytopathogenic Effect, Viral; Herpesvirus 1, Human; Humans; Organ Culture Techniques; Taurine; Vaccinia virus; Virulence | 2010 |
Antiaggregant effect of taurine chloramines in the presence of serum albumin.
Topics: Animals; Chloramines; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Serum Albumin; Taurine | 2009 |
(-)-Epicatechin enhances the chlorinating activity of human myeloperoxidase.
Topics: Catechin; Cyclohexanones; Halogenation; Humans; Peroxidase; Taurine | 2010 |
Taurine chloramine induces heme oxygenase-1 expression via Nrf2 activation in murine macrophages.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Cell Line; Electrophoretic Mobility Shift Assay; Enzyme Induction; Enzyme Inhibitors; Fluoresceins; Glutathione; Heme Oxygenase-1; Macrophages; Mice; NF-E2-Related Factor 2; Nitric Oxide; Phagocytosis; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Taurine; Translocation, Genetic; Up-Regulation | 2010 |
Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite.
Topics: Anti-Infective Agents; Chloramines; Chlorine; Disinfection; Escherichia coli; Humans; Hypochlorous Acid; Macromolecular Substances; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Taurine; Thiocyanates; Trinitrobenzenesulfonic Acid; Ubiquitin | 2010 |
Oxidation of melatonin by taurine chloramine.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hypochlorous Acid; Iodides; Kinetics; Kynuramine; Melatonin; Oxidation-Reduction; Taurine | 2010 |
[Therapy-resistant otitis externa with additional tympanic membrane perforation: local therapy using N-chlorotaurine and dexamethasone].
Topics: Anti-Inflammatory Agents; Dexamethasone; Drug Combinations; Female; Humans; Middle Aged; Otitis Externa; Taurine; Treatment Failure; Treatment Outcome; Tympanic Membrane Perforation | 2010 |
Effect of taurine chloramine on the production of matrix metalloproteinases (MMPs) in adiponectin- or IL-1beta-stimulated fibroblast-like synoviocytes.
Topics: Adiponectin; Arthritis, Rheumatoid; Cell Nucleus; Cells, Cultured; Enzyme Inhibitors; Humans; I-kappa B Proteins; Interleukin-1beta; Isoenzymes; Matrix Metalloproteinases; NF-kappa B; NF-KappaB Inhibitor alpha; Signal Transduction; Synovial Membrane; Taurine | 2010 |
Oxidative stress enhances granulocytic differentiation in HL 60 cells, an acute promyelocytic leukemia cell line.
Topics: CD11b Antigen; Cell Differentiation; Cell Separation; Flow Cytometry; Granulocytes; Heme Oxygenase-1; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Oxidants; Oxidation-Reduction; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Taurine | 2010 |
Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest.
Topics: Catalysis; Drug Evaluation; Hydrogen Peroxide; Hydrogen Sulfide; Hypochlorous Acid; In Vitro Techniques; Nitrogen Dioxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Peroxynitrous Acid; Taurine | 2011 |
In vitro activity of N-chlorotaurine (NCT) in combination with NH4Cl against Trichomonas vaginalis.
Topics: Ammonium Chloride; Antiprotozoal Agents; Cell Survival; Drug Synergism; Humans; Taurine; Trichomonas vaginalis | 2011 |
Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog.
Topics: Animals; Anti-Infective Agents; Cell Line; Drug Stability; Escherichia coli Infections; Hydrogen-Ion Concentration; Mice; Rats; Rats, Sprague-Dawley; Taurine | 2011 |
Taurine chloramine inhibits NO and TNF-α production in zymosan plus interferon-γ activated RAW 264.7 cells.
Topics: Animals; Blotting, Western; Dose-Response Relationship, Drug; Inflammation; Interferon-gamma; Macrophages; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger; Taurine; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 2011 |
Taurine chloramine inhibits osteoclastogenesis and splenic lymphocyte proliferation in mice with collagen-induced arthritis.
Topics: Animals; Arthritis, Experimental; Bone Diseases; Bone Marrow Cells; Cell Proliferation; Lymphocytes; Male; Mice; Mice, Inbred DBA; Osteoclasts; Spleen; Synovial Fluid; Taurine | 2011 |
Tolerability of inhaled N-chlorotaurine in an acute pig streptococcal lower airway inflammation model.
Topics: Administration, Inhalation; Animals; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Colony Count, Microbial; Disease Models, Animal; Streptococcal Infections; Streptococcus pyogenes; Swine; Swine Diseases; Taurine; Treatment Outcome | 2011 |
The free amino acid tyrosine enhances the chlorinating activity of human myeloperoxidase.
Topics: Antioxidants; Cells, Cultured; Halogenation; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Microscopy, Fluorescence; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds; Taurine; Tyrosine | 2012 |
Antimicrobial and anticoagulant activities of N-chlorotaurine, N,N-dichloro-2,2-dimethyltaurine, and N-monochloro-2,2-dimethyltaurine in human blood.
Topics: Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Blood Coagulation; Blood Coagulation Tests; Buffers; Candida albicans; Escherichia coli; Heparin; Humans; In Vitro Techniques; International Normalized Ratio; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Solutions; Taurine; Thrombin | 2012 |
Taurine chloramine induces apoptosis in human osteosarcoma cell lines.
Topics: Acridine Orange; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Separation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hypochlorous Acid; Microscopy, Fluorescence; Osteosarcoma; Taurine; Time Factors | 2012 |
N-chlorotaurine and its analogues N,N-dichloro-2,2-dimethyltaurine and N-monochloro-2,2-dimethyltaurine are safe and effective bactericidal agents in ex vivo corneal infection models.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Cornea; Disease Models, Animal; Eye Infections, Bacterial; Keratitis; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus; Swine; Taurine; Treatment Outcome | 2012 |
N-chlorotaurine, a long-lived oxidant produced by human leukocytes, inactivates Shiga toxin of enterohemorrhagic Escherichia coli.
Topics: Amino Acid Sequence; Animals; Cell Death; Chlorocebus aethiops; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Enterohemorrhagic Escherichia coli; Flow Cytometry; Humans; Kidney Glomerulus; Leukocytes; Mass Spectrometry; Models, Biological; Molecular Sequence Data; Oxidants; Oxidation-Reduction; Protein Binding; Shiga Toxin 2; Taurine; Vero Cells | 2012 |
Active halogen compounds and proteinaceous material: loss of activity of topical anti-infectives by halogen consumption.
Topics: Amines; Animals; Anti-Infective Agents, Local; Bromine; Cattle; Chloramines; Drug Interactions; Halogens; Hydrogen-Ion Concentration; Hypochlorous Acid; Oxidants; Oxidation-Reduction; Peptones; Serum; Taurine; Tosyl Compounds; Triazines | 2013 |
Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes.
Topics: Adipocytes; Adipogenesis; Cell Dedifferentiation; Cell Differentiation; Gene Expression Regulation; Humans; Lipid Metabolism; Organ Specificity; Taurine | 2013 |
Taurine chloramine administered in vivo increases NRF2-regulated antioxidant enzyme expression in murine peritoneal macrophages.
Topics: Animals; Antioxidants; Bone Marrow Cells; Heme Oxygenase-1; Injections, Intraperitoneal; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Taurine | 2013 |
Influence of taurine haloamines (TauCl and TauBr) on the development of Pseudomonas aeruginosa biofilm: a preliminary study.
Topics: Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Deoxyribonucleases; Humans; Kinetics; Microbial Sensitivity Tests; Microbial Viability; Plankton; Pseudomonas aeruginosa; Taurine | 2013 |
3,3',5,5'-Tetramethylbenzidine in hypochlorous acid and taurine chloramine scavenging assays: interference of dimethyl sulfoxide and other vehicles.
Topics: Benzidines; Dimethyl Sulfoxide; Ethanol; Glycerol; Hypochlorous Acid; Oxidation-Reduction; Quercetin; Taurine | 2013 |
Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study.
Topics: Copper; Cytochromes c; Glycosaminoglycans; Kinetics; Photolysis; Superoxides; Taurine | 2013 |
Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors.
Topics: Animals; Carboxylic Acids; Crystallization; Drug Design; Enzyme Inhibitors; Fluorine; Humans; Indicators and Reagents; Indoles; Lipoproteins, LDL; Male; Models, Molecular; Nitrogen; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Sulfur; Taurine | 2013 |
Inflammatory mediators are inhibited by a taurine metabolite in CpG oligodeoxynucleotide and IFN-r activated macrophage cell line.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation Mediators; Interferon-gamma; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oligodeoxyribonucleotides; RNA, Messenger; Taurine; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha | 2013 |
Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells.
Topics: Gene Knockdown Techniques; HEK293 Cells; Humans; Methionine Sulfoxide Reductases; Oxidants; Oxidative Stress; Protein Interaction Maps; Proteome; RNA Interference; Taurine | 2013 |
Taurine chloramine modulates the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes.
Topics: Adipocytes; Adipokines; Cell Differentiation; Cells, Cultured; Humans; Inflammation; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship; Taurine | 2013 |
[Efficacy of taurine haloamines and chlorhexidine against selected oral microbiome species].
Topics: Anti-Infective Agents, Local; Anti-Inflammatory Agents; Chlorhexidine; Dental Caries; Dental Plaque; Drug Interactions; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Microbiota; Periodontitis; Porphyromonas gingivalis; Sodium Hypochlorite; Streptococcus mutans; Taurine | 2013 |
Bactericidal activity of N-chlorotaurine against biofilm-forming bacteria grown on metal disks.
Topics: Anti-Bacterial Agents; Biofilms; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Taurine | 2014 |
Inhibition of plasma coagulation and platelet aggregation with structural analogs of taurine chloramine.
Topics: Blood Coagulation; Blood Platelets; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Taurine | 2014 |
Taurine chloramine-induced inactivation of cofilin protein through methionine oxidation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Substitution; Binding Sites; Dithiothreitol; Humans; Methionine; Methionine Sulfoxide Reductases; Models, Molecular; Oxidation-Reduction; Phosphorylation; Protein Binding; Taurine | 2014 |
Influence of poly-N-acetylglucosamine in the extracellular matrix on N-chlorotaurine mediated killing of Staphylococcus epidermidis.
Topics: Acetylglucosamine; Biofilms; Extracellular Matrix; Staphylococcus epidermidis; Taurine | 2014 |
Kinetic method for assaying the halogenating activity of myeloperoxidase based on reaction of celestine blue B with taurine halogenamines.
Topics: Bromides; Ceruloplasmin; Coloring Agents; Enzyme Assays; Enzyme Inhibitors; Halogenation; HL-60 Cells; Humans; Kinetics; Neutrophils; Oxazines; Peroxidase; Taurine | 2015 |
Taurine Chloramine Stimulates Efferocytosis Through Upregulation of Nrf2-Mediated Heme Oxygenase-1 Expression in Murine Macrophages: Possible Involvement of Carbon Monoxide.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carbon Monoxide; Cytoskeletal Proteins; Disease Models, Animal; Heme Oxygenase-1; Humans; Inflammation; Jurkat Cells; Kelch-Like ECH-Associated Protein 1; Macrophages; Macrophages, Peritoneal; Mice; NF-E2-Related Factor 2; Phagocytosis; Taurine; Up-Regulation; Zymosan | 2015 |
Taurine Chloramine, a Taurine Metabolite from Activated Neutrophils, Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression.
Topics: Animals; Cells, Cultured; Down-Regulation; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Neutrophil Activation; Neutrophils; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Taurine | 2015 |
Impact of Taurine on Innate and Adaptive Immunity as the Result of HOCl Neutralization.
Topics: Adaptive Immunity; Albumins; alpha 1-Antitrypsin; Animals; Antibody Formation; Hypochlorous Acid; Immunity, Innate; Inflammation; Mice; Mice, Inbred CBA; Ovalbumin; Oxidation-Reduction; Protein Processing, Post-Translational; Taurine | 2015 |
N-Chlorotaurine Exhibits Fungicidal Activity against Therapy-Refractory Scedosporium Species and Lomentospora prolificans.
Topics: Ammonium Chloride; Animals; Anti-Infective Agents, Local; Antifungal Agents; Cell Membrane; Cell Membrane Permeability; Cell Wall; Chloramines; Hyphae; Larva; Microbial Sensitivity Tests; Moths; Scedosporium; Spores, Fungal; Taurine | 2015 |
Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase.
Topics: Chlorides; Enzyme Assays; Enzyme Inhibitors; Humans; Kinetics; Leukocytes; Mesna; Models, Chemical; Peroxidase; Solutions; Taurine | 2017 |
Taurine chloramine potentiates phagocytic activity of peritoneal macrophages through up-regulation of dectin-1 mediated by heme oxygenase-1-derived carbon monoxide.
Topics: Animals; Candida albicans; Carbon Monoxide; Cells, Cultured; Enzyme Inhibitors; Heme Oxygenase-1; Lectins, C-Type; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Phagocytosis; PPAR gamma; Taurine; Up-Regulation | 2018 |
Role of heme oxygenase-1 in potentiation of phagocytic activity of macrophages by taurine chloramine: Implications for the resolution of zymosan A-induced murine peritonitis.
Topics: Animals; Antioxidants; Heme Oxygenase-1; Inflammation; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Peritonitis; Phagocytes; Phagocytosis; RAW 264.7 Cells; Taurine; Up-Regulation; Zymosan | 2018 |
The endogenous antiseptic N-chlorotaurine irreversibly inactivates Chlamydia pneumoniae and Chlamydia trachomatis.
Topics: Anti-Infective Agents, Local; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila Infections; Chlamydophila pneumoniae; Humans; Taurine | 2018 |
Exposure to N-chlorotaurine induces oxidative stress responses in Aspergillus fumigatus.
Topics: Amino Acids; Aspergillus fumigatus; Chromatography, High Pressure Liquid; Fungal Proteins; Gliotoxin; Humans; Mycelium; Oxidative Stress; Permeability; Proteomics; Ribosomal Proteins; Spores, Fungal; Taurine | 2019 |
Inactivation of Adenovirus in Water by Natural and Synthetic Compounds.
Topics: Adenoviridae Infections; Adenoviruses, Human; Disinfectants; Disinfection; Fresh Water; Grape Seed Extract; Humans; Sulfonamides; Taurine; Virus Inactivation | 2019 |
Swift Cure of a Chronic Wound Infected With Multiresistant
Topics: Administration, Topical; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents; Chronic Disease; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Kidney Failure, Chronic; Lower Extremity; Prognosis; Risk Assessment; Staphylococcal Infections; Taurine; Wound Healing; Wound Infection | 2019 |
N-chlorotaurine Inactivates Acanthamoeba and Candida albicans in the Porcine Ex Vivo Corneal Infection Model.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Animals; Anti-Infective Agents; Candida albicans; Candidiasis; Cornea; Eye Infections, Fungal; Eye Infections, Parasitic; Models, Biological; Swine; Taurine | 2019 |
Taurine Chloramine Inhibits Osteoclastic Differentiation and Osteoclast Marker Expression in RAW 264.7 Cells.
Topics: Animals; Cell Differentiation; Mice; Osteoclasts; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Taurine; Transcription Factors | 2019 |
Microbicidal activity of N-chlorotaurine can be enhanced in the presence of lung epithelial cells.
Topics: Anti-Infective Agents; Antifungal Agents; Candida albicans; Cells, Cultured; Cystic Fibrosis; Epithelial Cells; Exophiala; Lung; Pseudomonas aeruginosa; Staphylococcus aureus; Taurine | 2020 |
Taurine chloramine selectively regulates neutrophil degranulation through the inhibition of myeloperoxidase and upregulation of lactoferrin.
Topics: Animals; Cell Degranulation; Cell Survival; Extracellular Traps; Lactoferrin; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Taurine; Tetradecanoylphorbol Acetate | 2020 |
Taurine Chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats.
Topics: Animals; Cell Survival; Cells, Cultured; Cytokines; Lymphocytes; Rats; Sepsis; Spleen; Taurine | 2020 |
N-chlorotaurine, a potent weapon against multiresistant bacteria.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Taurine | 2021 |
Reactive Chlorine Species Reversibly Inhibit DnaB Protein Splicing in Mycobacteria.
Topics: Chloramines; Chlorine; DNA Replication; DnaB Helicases; Gene Expression Regulation, Bacterial; Hypochlorous Acid; Inteins; Mycobacterium leprae; Mycobacterium smegmatis; Oxidants; Oxidation-Reduction; Protein Splicing; Reactive Oxygen Species; Taurine | 2021 |
N-chlorotaurine is highly active against respiratory viruses including SARS-CoV-2 (COVID-19)
Topics: COVID-19 Drug Treatment; Humans; Influenza A Virus, H3N2 Subtype; Respiratory Syncytial Viruses; Respiratory Tract Infections; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Taurine | 2022 |
Examination of Taurine Chloramine and Taurine on LPS-Induced Acute Pulmonary Inflammatory in Mice.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; COVID-19; Interleukin-6; Lipopolysaccharides; Mice; Taurine | 2022 |
Taurine Chloramine Inhibits Leukocyte Migration by Suppressing Actin Polymerization and Extracellular Signal-Regulated Kinase.
Topics: Actins; Animals; Extracellular Signal-Regulated MAP Kinases; Inflammation; Lipopolysaccharides; Mammals; Neutrophils; Nitric Oxide; Polymerization; Taurine | 2022 |
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Hypochlorous Acid; Salmonella typhimurium; Taurine | 2023 |