n-chlorotaurine has been researched along with mocetinostat in 21 studies
| Studies (n-chlorotaurine) | Trials (n-chlorotaurine) | Recent Studies (post-2010) (n-chlorotaurine) | Studies (mocetinostat) | Trials (mocetinostat) | Recent Studies (post-2010) (mocetinostat) |
|---|---|---|---|---|---|
| 218 | 12 | 55 | 21,735 | 390 | 8,606 |
| Protein | Taxonomy | n-chlorotaurine (IC50) | mocetinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.7851 | |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | 0.022 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.57 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.102 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.102 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.3433 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3537 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.6386 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.6725 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.045 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bozeman, PM; Learn, DB; Thomas, EL | 1 |
| Beck-Speier, I; Hinze, H; Leuschel, L; Maier, KL; Matejkova, E; Weber, H | 1 |
| Hesse, D; Vogt, W | 1 |
| Dunford, HB; Marquez, LA | 1 |
| Cohen, MS; Gunther, MR; Mao, J | 1 |
| McNeil, J; Shabani, F; Tippett, L | 1 |
| Stanbro, WD | 1 |
| Connolly, DT; Heuvelman, DM; Hope, HR; Jennings, M; Lewis, C; Remsen, EE; Walker, MC | 1 |
| Biedroń, R; Bobek, M; Chain, BM; Gluszko, P; Kontny, E; Kwaśny-Krochin, B; Marcinkiewicz, J; Maśliński, W | 1 |
| Marcinkiewicz, J | 1 |
| Campa, A; Catalani, LH; Kettle, AJ; Maghzal, GJ; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Bishop, C; Brooks, WM; Dypbukt, JM; Eriksson, H; Kettle, AJ; Thong, B | 1 |
| Ekremoğlu, M; Erdamar, H; Kurt, Y; Türközkan, N; Yaman, H | 1 |
| Kanayama, A; Miyamoto, Y | 1 |
| Cortijo, J; Martinez-Losa, M; Morcillo, EJ; Piqueras, L; Sanz, MJ | 1 |
| Arnhold, J; Flemmig, J; Furtmüller, PG; Kirchner, T; Obinger, C | 1 |
| Arnhold, J; Sokolov, AV; Vlasova, II | 1 |
| Aldib, I; Colet, JM; Conotte, R; Dufrasne, F; Elfving, B; Furtmüller, PG; Gelbcke, M; Kauffmann, JM; Nève, J; Obinger, C; Podrecca, M; Prévost, M; Reye, F; Rousseau, A; Sarakbi, A; Soubhye, J; Van Antwerpen, P; Vanhaeverbeek, M; Zouaoui Boudjeltia, K | 1 |
| Donskyi, IS; Kostevich, VA; Kozlov, SO; Panasenko, OM; Rudenko, AO; Sokolov, AV; Vasilyev, VB; Vlasova, II; Zakharova, ET | 1 |
| Abu-Soud, HM; Aldhaheri, SR; Andreana, P; Jahanbakhsh, S; Jeelani, R; Khan, S; Kohan-Ghadr, HR; Morris, R; Thakur, M; Yang, Z | 1 |
| Kang, IS; Kim, C; Kim, DG; Kwon, YM | 1 |
1 review(s) available for n-chlorotaurine and mocetinostat
| Article | Year |
|---|---|
Prostanoids and MPO-halide system products as a link between innate and adaptive immunity.
Topics: Animals; Humans; Immune System; Immunity, Innate; Peroxidase; Prostaglandins; Taurine | 2003 |
20 other study(ies) available for n-chlorotaurine and mocetinostat
| Article | Year |
|---|---|
Inhibition of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase by dapsone.
Topics: Benzidines; Bromides; Chlorides; Dapsone; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrogen-Ion Concentration; Leukocytes; Oxidation-Reduction; Peroxidase; Peroxidases; Spectrophotometry; Taurine | 1992 |
Different selectivities of oxidants during oxidation of methionine residues in the alpha-1-proteinase inhibitor.
Topics: alpha 1-Antitrypsin; Animals; Blood Proteins; Chlorides; Chlorobenzoates; Hydrogen Peroxide; Methionine; Neutrophils; Oxidation-Reduction; Ozone; Pancreatic Elastase; Peroxidase; Swine; Taurine; Xanthine Oxidase | 1989 |
Oxidants generated by the myeloperoxidase-halide system activate the fifth component of human complement, C5.
Topics: Complement Activation; Complement C5; Electrophoresis, Polyacrylamide Gel; Humans; Hypochlorous Acid; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Taurine | 1994 |
Chlorination of taurine by myeloperoxidase. Kinetic evidence for an enzyme-bound intermediate.
Topics: Animals; Cattle; Chlorides; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Mathematics; Models, Theoretical; Peroxidase; Protein Binding; Spleen; Taurine | 1994 |
Oxidant-scavenging activities of ampicillin and sulbactam and their effects on neutrophil functions.
Topics: Ampicillin; Blood Bactericidal Activity; Free Radical Scavengers; Humans; Luminescent Measurements; Neutrophils; Oxidants; Peroxidase; Sodium Hypochlorite; Sulbactam; Taurine; Zymosan | 1993 |
The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCI) is suppressed by anti-rheumatic drugs.
Topics: Animals; Antioxidants; Antirheumatic Agents; Auranofin; Aurothioglucose; Cell Line; Chlorocebus aethiops; Chloroquine; Collagenases; Gold Sodium Thiomalate; Humans; Hypochlorous Acid; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Methotrexate; Neutrophils; Oxidants; Oxidation-Reduction; Penicillamine; Peptide Fragments; Peroxidase; Recombinant Fusion Proteins; Respiratory Burst; Structure-Activity Relationship; Taurine; Tissue Inhibitor of Metalloproteinase-1 | 1998 |
A kinetic model of the myeloperoxidase-hydrogen peroxide-chloride ion system in phagolysosomes.
Topics: Animals; Chlorides; Hydrogen Peroxide; Mammals; Models, Biological; Neutrophils; Oxidative Stress; Peroxidase; Peroxides; Phagosomes; Taurine; Tyrosine | 1998 |
Large-scale purification of myeloperoxidase from HL60 promyelocytic cells: characterization and comparison to human neutrophil myeloperoxidase.
Topics: Benzidines; Blotting, Western; Chromatography, Gel; Dapsone; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme Stability; HL-60 Cells; Humans; Molecular Weight; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Denaturation; Taurine; Ultracentrifugation | 2000 |
Effect of taurine chloramine, the product of activated neutrophils, on the development of collagen-induced arthritis in DBA 1/J mice.
Topics: Animals; Arthritis, Experimental; Collagen; Interleukin-6; Macrophages, Peritoneal; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neutrophil Activation; Neutrophils; Nitric Oxide; Peroxidase; Taurine; Tumor Necrosis Factor-alpha | 2002 |
Superoxide-dependent oxidation of melatonin by myeloperoxidase.
Topics: Animals; Antioxidants; Catalase; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kynuramine; Liver; Mass Spectrometry; Melatonin; Models, Chemical; Neutrophils; Oxygen; Ozone; Peroxidase; Protein Binding; Superoxides; Taurine; Time Factors; Xanthine Oxidase | 2005 |
A sensitive and selective assay for chloramine production by myeloperoxidase.
Topics: Benzidines; Bromides; Chloramines; Humans; Hypochlorous Acid; Iodides; Neutrophils; Peroxidase; Rhodamines; Sensitivity and Specificity; Taurine | 2005 |
The effect of taurine on polymorphonuclear leukocyte functions in endotoxemia.
Topics: Animals; Endotoxemia; Endotoxins; Guinea Pigs; Male; Neutrophils; Nitric Oxide; Peroxidase; Random Allocation; Taurine | 2007 |
Apoptosis triggered by phagocytosis-related oxidative stress through FLIPS down-regulation and JNK activation.
Topics: Antiviral Agents; Apoptosis; Blotting, Western; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cell Survival; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kidney; MAP Kinase Kinase Kinase 5; Neutrophils; NF-kappa B; Oxidative Stress; Peroxidase; Phagocytosis; Protein Serine-Threonine Kinases; Taurine; Tumor Necrosis Factor-alpha | 2007 |
Taurine chloramine inhibits functional responses of human eosinophils in vitro.
Topics: Apoptosis; Calcium; Cells, Cultured; Enzyme Inhibitors; Eosinophil Cationic Protein; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-5; Leukotriene C4; NADPH Oxidases; NF-kappa B; Peroxidase; Phosphoproteins; Respiratory Burst; Superoxides; Taurine | 2009 |
(-)-Epicatechin enhances the chlorinating activity of human myeloperoxidase.
Topics: Catechin; Cyclohexanones; Halogenation; Humans; Peroxidase; Taurine | 2010 |
The free amino acid tyrosine enhances the chlorinating activity of human myeloperoxidase.
Topics: Antioxidants; Cells, Cultured; Halogenation; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Microscopy, Fluorescence; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds; Taurine; Tyrosine | 2012 |
Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors.
Topics: Animals; Carboxylic Acids; Crystallization; Drug Design; Enzyme Inhibitors; Fluorine; Humans; Indicators and Reagents; Indoles; Lipoproteins, LDL; Male; Models, Molecular; Nitrogen; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Sulfur; Taurine | 2013 |
Kinetic method for assaying the halogenating activity of myeloperoxidase based on reaction of celestine blue B with taurine halogenamines.
Topics: Bromides; Ceruloplasmin; Coloring Agents; Enzyme Assays; Enzyme Inhibitors; Halogenation; HL-60 Cells; Humans; Kinetics; Neutrophils; Oxazines; Peroxidase; Taurine | 2015 |
Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase.
Topics: Chlorides; Enzyme Assays; Enzyme Inhibitors; Humans; Kinetics; Leukocytes; Mesna; Models, Chemical; Peroxidase; Solutions; Taurine | 2017 |
Taurine chloramine selectively regulates neutrophil degranulation through the inhibition of myeloperoxidase and upregulation of lactoferrin.
Topics: Animals; Cell Degranulation; Cell Survival; Extracellular Traps; Lactoferrin; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Taurine; Tetradecanoylphorbol Acetate | 2020 |