Compounds > n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide
Page last updated: 2024-09-03

n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide and warfarin

n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide has been researched along with warfarin in 5 studies

Compound Research Comparison

Studies
(n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide)		Trials
(n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide)		Recent Studies (post-2010)
(n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide)		Studies
(warfarin)		Trials
(warfarin)		Recent Studies (post-2010) (warfarin)
60136,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomyn-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koida, M; Ogita, K; Tsuru, D; Walter, R; Yoshimoto, T1
De Meester, I; Goossens, F; Scharpé, S; Vanhoof, G1
Cunningham, DF; O'Connor, B2
Grubb, A; Momeni, N; Ryberg, B; Sandberg-Wollheim, M; Yoshimoto, T1

Other Studies

5 other study(ies) available for n-carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide and warfarin

ArticleYear
Post-proline cleaving enzyme. Synthesis of a new fluorogenic substrate and distribution of the endopeptidase in rat tissues and body fluids of man.
    Biochimica et biophysica acta, 1979, Aug-15, Volume: 569, Issue:2

    Topics: Aminohydrolases; Animals; Chemical Phenomena; Chemistry; Coumarins; Endopeptidases; Esterases; Humans; Kidney; Male; Oligopeptides; Prolyl Oligopeptidases; Rats; Serine Endopeptidases; Sheep; Spectrometry, Fluorescence; Tissue Distribution

1979
A sensitive method for the assay of serum prolyl endopeptidase.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1992, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Buffers; Coumarins; Evaluation Studies as Topic; Fluorometry; Humans; Hydrogen-Ion Concentration; Middle Aged; Prolyl Oligopeptidases; Sensitivity and Specificity; Serine Endopeptidases; Substrate Specificity

1992
Identification and initial characterisation of a N-benzyloxycarbonyl-prolyl-prolinal (Z-Pro-prolinal)-insensitive 7-(N-benzyloxycarbonyl-glycyl-prolyl-amido)-4-methylcoumarin (Z-Gly-Pro-NH-Mec)-hydrolysing peptidase in bovine serum.
    European journal of biochemistry, 1997, Mar-15, Volume: 244, Issue:3

    Topics: Animals; Cattle; Coumarins; Dipeptides; Hydrolysis; In Vitro Techniques; Kinetics; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity

1997
A study of prolyl endopeptidase in bovine serum and its relevance to the tissue enzyme.
    The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:1

    Topics: Angiotensin II; Animals; Binding, Competitive; Bradykinin; Cattle; Chloromercuribenzoates; Coumarins; Enzyme Inhibitors; Enzyme Stability; Fluorometry; Gonadotropin-Releasing Hormone; Hydrogen-Ion Concentration; Metals; Molecular Weight; Neuropeptides; p-Chloromercuribenzoic Acid; Prolyl Oligopeptidases; Serine Endopeptidases; Substance P; Substrate Specificity

1998
Factors influencing analysis of prolyl endopeptidase in human blood and cerebrospinal fluid: increase in assay sensitivity.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:6

    Topics: Adult; Clinical Laboratory Techniques; Coumarins; Enzyme Inhibitors; Humans; Middle Aged; Prolyl Oligopeptidases; Reproducibility of Results; Sensitivity and Specificity; Serine Endopeptidases; Solvents; Temperature

2003