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n-butoxyacetic acid and n-butoxyethanol

n-butoxyacetic acid has been researched along with n-butoxyethanol in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.79)18.7374
1990's12 (41.38)18.2507
2000's11 (37.93)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jönsson, AK; Steen, G1
Johanson, G; Johnsson, S1
Ghanayem, BI1
Burka, LT; Ghanayem, BI; Matthews, HB1
Byfält Nordqvist, M; Johanson, G; Kronborg, H; Näslund, PH1
Bartels, MJ; Bormett, GA; Markham, DA1
Araki, T; Masuyama, Y; Morita, Y; Sakai, T1
Bormett, GA; Corley, RA; Ghanayem, BI1
Johanson, G2
Ghanayem, BI; Sullivan, CA1
Birnbaum, LS; Henderson, RF; Medinsky, MA; Sabourin, PJ; Shyr, LJ1
Hennigs, R; Rettenmeier, AW; Wodarz, R1
Banks, C; Corley, RA; Delorme, P; Houle, JM; Markham, DA; Masterman, A1
Ashby, J; Elliott, BM1
Anderson, DJ; Bates, DJ; Burka, LT; Chou, BJ; Dill, JA; Johnson, RE; Lee, KM; Roycroft, JH1
Dartsch, PC; Gfrörer, W; Hildenbrand, S; Schmahl, FW1
Kamendulis, LM; Klaunig, JE; Park, J2
Brown, KK; Butler, MA; Cheever, KL; McLaurin, JL; Shaw, PB1
Jakasa, I; Kezic, S; Krüse, J; Mohammadi, N1
Boatman, RJ; Deisinger, PJ1
Jakasa, I; Kezic, S; Meuling, WJ1
Cocker, J; Franks, SJ; Loizou, GD; Spendiff, MK1
Corthals, SM; Kamendulis, LM; Klaunig, JE1
Mehendale, HM; Palkar, PS; Philip, BK; Reddy, RN1
Traynor, MJ; Wilkinson, SC; Williams, FM1
Dabrowská, L; Dusková, S; Kucera, J; Sperlingová, I; Stránský, V; Tichy, M; Tvrdíková, M1
Cheng, SF; Hung, PC; Liou, SH; Tsai, SW1

Reviews

1 review(s) available for n-butoxyacetic acid and n-butoxyethanol

ArticleYear
Review of the genotoxicity of 2-butoxyethanol.
    Mutation research, 1997, Volume: 387, Issue:2

    Topics: Acetaldehyde; Animals; Ethylene Glycols; Female; Glycolates; Humans; Male; Mutagenicity Tests; Mutagens; Mutation

1997

Trials

1 trial(s) available for n-butoxyacetic acid and n-butoxyethanol

ArticleYear
Physiologically based pharmacokinetics and the dermal absorption of 2-butoxyethanol vapor by humans.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 39, Issue:2

    Topics: Adult; Carbon Isotopes; Ethylene Glycols; Glutamine; Glycolates; Humans; Male; Middle Aged; Occupational Exposure; Skin Absorption; Solvents; Volatilization

1997

Other Studies

27 other study(ies) available for n-butoxyacetic acid and n-butoxyethanol

ArticleYear
n-Butoxyacetic acid, a urinary metabolite from inhaled n-butoxyethanol (Butylcellosolve).
    Acta pharmacologica et toxicologica, 1978, Volume: 42, Issue:5

    Topics: Acetates; Animals; Chromatography, Gas; Ethers; Ethylene Glycols; Glycolates; Hippurates; Male; Mass Spectrometry; Rats; Trimethylsilyl Compounds

1978
Gas chromatographic determination of butoxyacetic acid in human blood after exposure to 2-butoxyethanol.
    Archives of toxicology, 1991, Volume: 65, Issue:5

    Topics: Absorption; Chromatography, Gas; Ethylene Glycols; Glycolates; Humans; Kidney; Male; Metabolic Clearance Rate

1991
Metabolic and cellular basis of 2-butoxyethanol-induced hemolytic anemia in rats and assessment of human risk in vitro.
    Biochemical pharmacology, 1989, May-15, Volume: 38, Issue:10

    Topics: Acetaldehyde; Acetates; Adenosine Triphosphate; Aldehyde Dehydrogenase; Anemia, Hemolytic; Animals; Erythrocytes; Ethanol; Ethylene Glycols; Glycolates; Humans; In Vitro Techniques; Male; Rats; Rats, Inbred F344; Risk

1989
Metabolic basis of ethylene glycol monobutyl ether (2-butoxyethanol) toxicity: role of alcohol and aldehyde dehydrogenases.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Biotransformation; Cyanamide; Deuterium; Ethylene Glycols; Glucuronates; Glycolates; Hematologic Diseases; Male; Pyrazoles; Rats; Rats, Inbred F344; Sulfates

1987
Toxicokinetics of inhaled 2-butoxyethanol (ethylene glycol monobutyl ether) in man.
    Scandinavian journal of work, environment & health, 1986, Volume: 12, Issue:6

    Topics: Acetates; Adult; Benzoates; Ethylene Glycols; Glycolates; Humans; Kinetics; Male; Physical Exertion

1986
Determination of 2-butoxyethanol and butoxyacetic acid in rat and human blood by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, Mar-24, Volume: 665, Issue:2

    Topics: Animals; Carbon Isotopes; Drug Stability; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Glucuronates; Glycolates; Humans; Male; Rats; Rats, Inbred F344; Sulfates

1995
Gaschromatographic determination of butoxyacetic acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol.
    International archives of occupational and environmental health, 1994, Volume: 66, Issue:4

    Topics: Chemical Industry; Chromatography, Gas; Environmental Monitoring; Ethylene Glycols; Glycolates; Humans; Hydrolysis; Occupational Exposure; Semiconductors

1994
Physiologically based pharmacokinetics of 2-butoxyethanol and its major metabolite, 2-butoxyacetic acid, in rats and humans.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:1

    Topics: Administration, Cutaneous; Administration, Inhalation; Administration, Oral; Animals; Body Weight; Computer Simulation; Ethylene Glycols; Glycolates; Hemolysis; Humans; Infusions, Intravenous; Kidney; Liver; Male; Models, Biological; Rats; Rats, Inbred F344; Solubility; Species Specificity; Tissue Distribution

1994
Inhalation toxicokinetics of butoxyethanol and its metabolite butoxyacetic acid in the male Sprague-Dawley rat.
    Archives of toxicology, 1994, Volume: 68, Issue:9

    Topics: Adaptation, Physiological; Administration, Inhalation; Animals; Ethylene Glycols; Glycolates; Male; Rats; Rats, Sprague-Dawley

1994
Assessment of the haemolytic activity of 2-butoxyethanol and its major metabolite, butoxyacetic acid, in various mammals including humans.
    Human & experimental toxicology, 1993, Volume: 12, Issue:4

    Topics: Anemia, Hemolytic; Animals; Cats; Dogs; Erythrocyte Count; Ethylene Glycols; Glycolates; Hematocrit; Hemolysis; Humans; In Vitro Techniques; Male; Papio; Rabbits; Rodentia; Swine

1993
Physiologically based modeling of 2-butoxyethanol disposition in rats following different routes of exposure.
    Environmental research, 1993, Volume: 63, Issue:2

    Topics: Administration, Cutaneous; Administration, Inhalation; Administration, Oral; Animals; Ethylene Glycols; Glycolates; Liver; Models, Biological; Rats; Rats, Inbred F344; Tissue Distribution

1993
Urine butoxyacid acid as a therapeutic guide.
    Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:3

    Topics: Ethylene Glycols; Glycolates; Humans

1993
Determination of butoxyacetic acid and N-butoxyacetyl-glutamine in urine of lacquerers exposed to 2-butoxyethanol.
    International archives of occupational and environmental health, 1993, Volume: 65, Issue:1 Suppl

    Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Ethylene Glycols; Glutamine; Glycolates; Humans; Lacquer; Occupational Exposure

1993
Toxicokinetics of inhaled 2-butoxyethanol and its major metabolite, 2-butoxyacetic acid, in F344 rats and B6C3F1 mice.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:2

    Topics: Administration, Inhalation; Age Factors; Animals; Dose-Response Relationship, Drug; Ethylene Glycols; Female; Glycolates; Male; Metabolic Clearance Rate; Mice; Rats; Rats, Inbred F344; Sex Characteristics; Solvents; Species Specificity; Time Factors

1998
New methods for determination of 2-butoxyethanol, butoxyacetaldehyde and butoxyacetic acid in aqueous systems, with special reference to cell culture conditions.
    Archives of toxicology, 2000, Volume: 74, Issue:2

    Topics: Acetaldehyde; Animal Testing Alternatives; Animals; Cell Culture Techniques; Cells, Cultured; Culture Media, Conditioned; Ethers; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Glycolates; Kidney Tubules, Proximal; Opossums; Oxidation-Reduction; Solvents; Water

2000
Effects of 2-butoxyethanol on hepatic oxidative damage.
    Toxicology letters, 2002, Jan-05, Volume: 126, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Ethylene Glycols; Ferrous Compounds; Glycolates; Hemolysis; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Malondialdehyde; Mice; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin E

2002
Mechanisms of 2-butoxyethanol carcinogenicity: studies on Syrian Hamster Embryo (SHE) cell transformation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:1

    Topics: Animals; Antioxidants; Catechin; Cell Transformation, Neoplastic; Cells, Cultured; Comet Assay; Cricetinae; DNA Damage; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Ethylene Glycols; Female; Ferrous Compounds; Glycolates; Mesocricetus; Mutagens; Pregnancy; Solvents; Vitamin E

2002
Synthesis, characterization, and use of 2-[(2H(9))butoxy]acetic acid and 2-(3-methylbutoxy)acetic acid as an internal standard and an instrument performance surrogate, respectively, for the gas chromatographic-mass spectrometric determination of 2-butoxya
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Jul-25, Volume: 792, Issue:2

    Topics: Calibration; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Reference Standards; Sensitivity and Specificity

2003
Percutaneous absorption of neat and aqueous solutions of 2-butoxyethanol in volunteers.
    International archives of occupational and environmental health, 2004, Volume: 77, Issue:2

    Topics: Adult; Ethylene Glycols; Glycolates; Humans; Male; Middle Aged; Netherlands; Skin Absorption

2004
In vivo metabolism and kinetics of ethylene glycol monobutyl ether and its metabolites, 2-butoxyacetaldehyde and 2-butoxyacetic acid, as measured in blood, liver and forestomach of mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:7

    Topics: Acetaldehyde; Administration, Oral; Animals; Dose-Response Relationship, Drug; Ethylene Glycols; Female; Gastric Mucosa; Glycolates; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Stomach; Tissue Distribution

2004
Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers.
    International archives of occupational and environmental health, 2004, Volume: 77, Issue:8

    Topics: Administration, Cutaneous; Administration, Inhalation; Adult; Ethylene Glycols; Glycolates; Half-Life; Humans; Male; Middle Aged; Skin Absorption

2004
Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol.
    Toxicology letters, 2006, Apr-10, Volume: 162, Issue:2-3

    Topics: Environmental Exposure; Ethylene Glycols; Glycolates; Humans; Models, Biological; Reproducibility of Results; Skin Absorption; Solvents; Urinary Bladder

2006
Mechanisms of 2-butoxyethanol-induced hemangiosarcomas.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 92, Issue:2

    Topics: Acetaldehyde; Animals; Cell Line; Comet Assay; DNA Damage; Endothelial Cells; Erythrocytes; Ethylene Glycols; Ferrous Compounds; Glycolates; Hemangiosarcoma; Hemolysis; Hydrogen Peroxide; Kupffer Cells; Macrophage Activation; Mice; Solvents; Tumor Necrosis Factor-alpha

2006
Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol.
    Toxicology and applied pharmacology, 2007, Nov-15, Volume: 225, Issue:1

    Topics: Aldehyde Dehydrogenase; Animals; Antioxidants; Erythrocytes; Erythropoiesis; Ethylene Glycols; Female; Glycolates; Hematocrit; Hemolysis; Oxidants; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Reticulocytes; Time Factors

2007
Metabolism of butoxyethanol in excised human skin in vitro.
    Toxicology letters, 2008, Apr-01, Volume: 177, Issue:3

    Topics: Ethylene Glycols; Glycolates; Humans; Skin; Skin Absorption

2008
Determination of butoxyacetic acid (biomarker of ethylene glycol monobutyl ether exposure) in human urine candidate reference material.
    Analytical and bioanalytical chemistry, 2010, Volume: 397, Issue:2

    Topics: Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Occupational Exposure; Reference Standards

2010
Biological monitoring of low-level 2-butoxyethanol exposure in decal transfer workers in bicycle manufacturing factories.
    Occupational and environmental medicine, 2011, Volume: 68, Issue:10

    Topics: Adult; Air Pollutants, Occupational; Creatine; Environmental Monitoring; Ethylene Glycols; Female; Glycolates; Hemoglobins; Humans; Industry; Inhalation Exposure; Male; Occupational Exposure; Skin Absorption

2011