Page last updated: 2024-09-03

n-bromoacetylthyroxine and thyroxine

n-bromoacetylthyroxine has been researched along with thyroxine in 16 studies

Compound Research Comparison

Studies
(n-bromoacetylthyroxine)
Trials
(n-bromoacetylthyroxine)
Recent Studies (post-2010)
(n-bromoacetylthyroxine)
Studies
(thyroxine)
Trials
(thyroxine)
Recent Studies (post-2010) (thyroxine)
160038,9891,4106,550

Protein Interaction Comparison

ProteinTaxonomyn-bromoacetylthyroxine (IC50)thyroxine (IC50)
TransthyretinHomo sapiens (human)2.1939
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)5.25
Solute carrier organic anion transporter family member 4C1Homo sapiens (human)8
Bile acid receptorHomo sapiens (human)7.86

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's12 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cahnmann, HJ; Cheng, SY; Robbins, J; Wilchek, M1
Cahnmann, HJ; Fales, HM; Gonçalves, E; Ito, Y; Sokoloski, EA1
Gondou, A; Inada, M; Masaki, H; Mori, Y; Nishikawa, M; Toyoda, N; Yonemoto, T; Yoshimura, M1
Arthur, JR; Beckett, GJ; Choudhury, K; Nicol, F; Peterson, FE; Rae, PW; Smith, AF; Toft, AD; Wu, PS1
Leonard, JL; Safran, M1
Ekenbarger, DM; Farwell, AP; Frank, SJ; Koehrle, J; Leonard, JL1
Hesch, RD; Köhrle, J; Leonard, JL; Rasmussen, UB; Rokos, H1
Braverman, LE; Köhrle, J; Leonard, JL; Safran, M1
Farwell, AP; Leonard, JL1
Korcek, L; Siegel, JS; Tabachnick, M1
Cheng, SY; Erard, F; Robbins, J1
Courtin, F; Esfandiari, A; Gavaret, JM; Lennon, AM; Pierre, M1
Köhrle, J; Schmutzler, C; Schnieders, F; Schreck, R1
Gross, M; Köhrle, J; Oertel, M; Rokos, H1
Farwell, AP; Leonard, JL; Safran, M1
Bartha, T; Harney, JW; Larsen, PR; Salvatore, D1

Other Studies

16 other study(ies) available for n-bromoacetylthyroxine and thyroxine

ArticleYear
Affinity labeling of human serum prealbumin with N-bromoacetyl-L-thyroxine.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Affinity Labels; Amino Acid Sequence; Amino Acids; Humans; Kinetics; Peptide Fragments; Prealbumin; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Thyroxine; Trypsin

1977
Synthesis and properties of N-bromoacetyl-L-thyroxine.
    Analytical biochemistry, 1992, Aug-01, Volume: 204, Issue:2

    Topics: Chemical Phenomena; Chemistry, Physical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet; Thyroxine

1992
Identification of a 27-kilodalton protein with the properties of type I iodothyronine 5'-deiodinase in human thyroid gland.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:3

    Topics: Adenocarcinoma, Papillary; Adenoma; Affinity Labels; Autoradiography; Electrophoresis, Polyacrylamide Gel; Graves Disease; Humans; Iodide Peroxidase; Iodine Radioisotopes; Isoenzymes; Kinetics; Thyroid Gland; Thyroid Neoplasms; Thyroxine

1992
Inter-relationships between selenium and thyroid hormone metabolism in the rat and man.
    Journal of trace elements and electrolytes in health and disease, 1991, Volume: 5, Issue:4

    Topics: Animals; Electrophoresis, Polyacrylamide Gel; Glutathione Peroxidase; Graves Disease; Humans; Hyperthyroidism; Iodine; Kidney; Male; Microsomes; Molecular Weight; Organ Size; Rats; Selenium; Thyroid Gland; Thyroid Hormones; Thyroid Nodule; Thyrotropin; Thyroxine

1991
Characterization of a N-bromoacetyl-L-thyroxine affinity-labeled 55-kilodalton protein as protein disulfide isomerase in cultured glial cells.
    Endocrinology, 1991, Volume: 129, Issue:4

    Topics: Affinity Labels; Animals; Astrocytes; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Isomerases; Microsomes, Liver; Molecular Weight; Peptide Mapping; Protein Disulfide-Isomerases; Thyroxine

1991
Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells.
    The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17

    Topics: Affinity Labels; Animals; Cell Line; Cell Membrane; Detergents; Epithelium; Iodide Peroxidase; Isoenzymes; Kidney Cortex; Kidney Glomerulus; Kinetics; Molecular Weight; Rats; Subcellular Fractions; Thyroxine

1991
Selective affinity labeling of a 27-kDa integral membrane protein in rat liver and kidney with N-bromoacetyl derivatives of L-thyroxine and 3,5,3'-triiodo-L-thyronine.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Affinity Labels; Animals; Carrier Proteins; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Iodine Radioisotopes; Kidney Cortex; Kinetics; Membrane Proteins; Microsomes; Microsomes, Liver; Molecular Weight; Peptide Fragments; Peptide Hydrolases; Peptide Mapping; Radioisotope Dilution Technique; Rats; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Thyroxine; Triiodothyronine

1990
Effect of biological alterations of type I 5'deiodinase activity on affinity labeled membrane proteins in rat liver and kidney.
    Endocrinology, 1990, Volume: 126, Issue:2

    Topics: Affinity Labels; Animals; Fasting; Iodide Peroxidase; Kidney; Male; Membrane Proteins; Methimazole; Microsomes; Microsomes, Liver; Molecular Weight; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine

1990
Identification of a 27-kDa protein with the properties of type II iodothyronine 5'-deiodinase in dibutyryl cyclic AMP-stimulated glial cells.
    The Journal of biological chemistry, 1989, Dec-05, Volume: 264, Issue:34

    Topics: Affinity Labels; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Cerebral Cortex; Iodide Peroxidase; Isoenzymes; Kinetics; Molecular Weight; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine

1989
Evaluation of N-bromoacetyl-L-thyroxine as an affinity label for the thyroxine (T4)-binding site in human T4-binding globulin.
    Endocrinology, 1983, Volume: 113, Issue:6

    Topics: Affinity Labels; Anilino Naphthalenesulfonates; Binding Sites; Binding, Competitive; Fluorescent Dyes; Humans; Protein Binding; Spectrometry, Fluorescence; Thyroxine; Thyroxine-Binding Proteins

1983
Affinity labeling of human serum thyroxine-binding globulin with N-bromoacetyl-L-thyroxine: identification of the labeled amino acid residues.
    Archives of biochemistry and biophysics, 1981, Volume: 206, Issue:1

    Topics: Affinity Labels; Amino Acids; Binding Sites; Binding, Competitive; Humans; Serum Globulins; Thyroxine; Thyroxine-Binding Proteins

1981
12-O-tetradecanoylphorbol 13-acetate and fibroblast growth factor increase the 30-kDa substrate binding subunit of type II deiodinase in astrocytes.
    Journal of neurochemistry, 1994, Volume: 62, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Affinity Labels; Animals; Astrocytes; Cells, Cultured; Fibroblast Growth Factor 1; Growth Substances; Iodide Peroxidase; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Thyroxine; Time Factors

1994
Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:3

    Topics: Adenocarcinoma, Follicular; Affinity Labels; Butyrates; Butyric Acid; Cycloheximide; Dactinomycin; Humans; Iodide Peroxidase; Isoenzymes; Kinetics; Retinoids; Thyroid Neoplasms; Thyroxine; Tretinoin; Triiodothyronine; Tumor Cells, Cultured

1994
Selenium-dependent regulation of type I 5'-deiodinase expression.
    The American journal of clinical nutrition, 1993, Volume: 57, Issue:2 Suppl

    Topics: Affinity Labels; Animals; Cell Line; Glutathione Peroxidase; Iodide Peroxidase; Kidney; Selenium; Selenium Radioisotopes; Swine; Thyroxine

1993
Catalytic activity of type II iodothyronine 5'-deiodinase polypeptide is dependent upon a cyclic AMP activation factor.
    The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27

    Topics: Affinity Labels; Animals; Animals, Newborn; Astrocytes; Binding Sites; Brain; Bucladesine; Catalysis; Cells, Cultured; Chromatography, Gel; Cyclic AMP; Endocytosis; Enzyme Activation; Immunohistochemistry; Iodide Peroxidase; Isoenzymes; Kinetics; Macromolecular Substances; Rats; Thyroxine

1996
Molecular biological and biochemical characterization of the human type 2 selenodeiodinase.
    Endocrinology, 1996, Volume: 137, Issue:8

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; DNA, Complementary; Humans; Iodide Peroxidase; Iodine Radioisotopes; Iodothyronine Deiodinase Type II; Kinetics; Molecular Biology; Molecular Sequence Data; Muscle, Skeletal; Oligonucleotide Probes; Organoselenium Compounds; Selenium Radioisotopes; Thyroxine; Triiodothyronine

1996