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n-benzyloxycarbonylprolylprolinal and n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine

n-benzyloxycarbonylprolylprolinal has been researched along with n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine in 5 studies

Compound Research Comparison

Studies
(n-benzyloxycarbonylprolylprolinal)
Trials
(n-benzyloxycarbonylprolylprolinal)
Recent Studies (post-2010)
(n-benzyloxycarbonylprolylprolinal)
Studies
(n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine)
Trials
(n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine)
Recent Studies (post-2010) (n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine)
39071703

Protein Interaction Comparison

ProteinTaxonomyn-benzyloxycarbonylprolylprolinal (IC50)n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine (IC50)
Prolyl endopeptidaseRattus norvegicus (Norway rat)0.0072
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.13
Prolyl endopeptidaseSus scrofa (pig)0.0297
Prolyl endopeptidaseHomo sapiens (human)0.0847
Prolyl endopeptidaseMus musculus (house mouse)0.0047
Prolyl endopeptidaseBos taurus (cattle)2.1

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arai, H; Ikeda, Y; Kobayashi, N; Nishioka, H; Niwa, S; Tanaka, Y; Torizuka, M; Yamanaka, T; Yoshinaga, K1
Benoist, A; De Nanteuil, G; Hervé, Y; Lepagnol, J; Portevin, B; Rémond, G; Vincent, M1
Christiaans, JA; Forsberg, MM; Gynther, J; Männistö, PT; Venäläinen, JI; Wallén, EA1
Christiaans, JA; Forsberg, MM; Gynther, J; Jarho, EM; Männistö, PT; Poso, A; Venäläinen, JI; Wallén, EA1
Gerber-Lemaire, S; Juillerat-Jeanneret, L; Lawandi, J; Moitessier, N1

Reviews

1 review(s) available for n-benzyloxycarbonylprolylprolinal and n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine

ArticleYear
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Blood-Brain Barrier; Central Nervous System; Humans; Prolyl Oligopeptidases; Protein Binding; Serine Endopeptidases; Serine Proteinase Inhibitors

2010

Other Studies

4 other study(ies) available for n-benzyloxycarbonylprolylprolinal and n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine

ArticleYear
New potent prolyl endopeptidase inhibitors: synthesis and structure-activity relationships of indan and tetralin derivatives and their analogues.
    Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13

    Topics: Animals; Brain; Dogs; In Vitro Techniques; Indans; Magnetic Resonance Spectroscopy; Proline; Prolyl Oligopeptidases; Pyrroles; Serine Endopeptidases; Serine Proteinase Inhibitors; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrahydronaphthalenes

1994
New prolyl endopeptidase inhibitors: in vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives.
    Journal of medicinal chemistry, 1996, Jun-07, Volume: 39, Issue:12

    Topics: Alzheimer Disease; Amino Acid Sequence; Amnesia; Animals; Avoidance Learning; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Conformation; Molecular Sequence Data; Nerve Tissue Proteins; Prolyl Oligopeptidases; Pyrroles; Rats; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship

1996
Dicarboxylic acid bis(L-prolyl-pyrrolidine) amides as prolyl oligopeptidase inhibitors.
    Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20

    Topics: Amides; Animals; Brain; Proline; Prolyl Oligopeptidases; Pyrrolidines; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship; Swine

2002
Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.
    Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

    Topics: Amides; Animals; Aza Compounds; Brain; Dicarboxylic Acids; In Vitro Techniques; Models, Molecular; Proline; Prolyl Oligopeptidases; Pyrrolidines; Quantitative Structure-Activity Relationship; Serine Endopeptidases; Serine Proteinase Inhibitors; Swine

2005