n-benzyloxycarbonylprolylprolinal has been researched along with jtp 4819 in 6 studies
| Studies (n-benzyloxycarbonylprolylprolinal) | Trials (n-benzyloxycarbonylprolylprolinal) | Recent Studies (post-2010) (n-benzyloxycarbonylprolylprolinal) | Studies (jtp 4819) | Trials (jtp 4819) | Recent Studies (post-2010) (jtp 4819) |
|---|---|---|---|---|---|
| 39 | 0 | 7 | 25 | 1 | 5 |
| Protein | Taxonomy | n-benzyloxycarbonylprolylprolinal (IC50) | jtp 4819 (IC50) |
|---|---|---|---|
| Prolyl endopeptidase | Rattus norvegicus (Norway rat) | 0.0001 | |
| Prolyl endopeptidase | Sus scrofa (pig) | 0.0002 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Benoist, A; De Nanteuil, G; Hervé, Y; Lepagnol, J; Portevin, B; Rémond, G; Vincent, M | 1 |
| Christiaans, JA; Forsberg, MM; Gynther, J; Jarho, EM; Männistö, PT; Poso, A; Venäläinen, JI; Wallén, EA | 1 |
| Gerber-Lemaire, S; Juillerat-Jeanneret, L; Lawandi, J; Moitessier, N | 1 |
| Airaghi, F; Auclair, K; De Cesco, S; Huskić, I; Kurian, J; Mariaule, G; Mittermaier, A; Moitessier, N; Rocheleau, S; Schiavini, P | 1 |
| Dufresne, C; Hédou, D; Labarre, A; Mittermaier, A; Moitessier, N; Plescia, J; Pousse, ME | 1 |
| Lehtonen, S; Männistö, PT; Puttonen, KA; Raasmaja, A | 1 |
1 review(s) available for n-benzyloxycarbonylprolylprolinal and jtp 4819
| Article | Year |
|---|---|
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.
Topics: Animals; Blood-Brain Barrier; Central Nervous System; Humans; Prolyl Oligopeptidases; Protein Binding; Serine Endopeptidases; Serine Proteinase Inhibitors | 2010 |
5 other study(ies) available for n-benzyloxycarbonylprolylprolinal and jtp 4819
| Article | Year |
|---|---|
New prolyl endopeptidase inhibitors: in vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives.
Topics: Alzheimer Disease; Amino Acid Sequence; Amnesia; Animals; Avoidance Learning; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Conformation; Molecular Sequence Data; Nerve Tissue Proteins; Prolyl Oligopeptidases; Pyrroles; Rats; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship | 1996 |
Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.
Topics: Amides; Animals; Aza Compounds; Brain; Dicarboxylic Acids; In Vitro Techniques; Models, Molecular; Proline; Prolyl Oligopeptidases; Pyrrolidines; Quantitative Structure-Activity Relationship; Serine Endopeptidases; Serine Proteinase Inhibitors; Swine | 2005 |
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.
Topics: Bridged Bicyclo Compounds; Carboxylic Acids; Humans; Isoindoles; Molecular Docking Simulation; Molecular Structure; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Stereoisomerism | 2016 |
Modulating the selectivity of inhibitors for prolyl oligopeptidase inhibitors and fibroblast activation protein-α for different indications.
Topics: Endopeptidases; Enzyme Inhibitors; Humans; Membrane Proteins; Neoplasms; Prolyl Oligopeptidases; Serine Endopeptidases | 2022 |
A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine.
Topics: Actins; Blotting, Western; Cell Line; Cell Survival; Cytarabine; Dipeptides; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Oxidopamine; Prolyl Oligopeptidases; Protease Inhibitors; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Reactive Oxygen Species; Serine Endopeptidases; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2006 |