n-benzyl-1-aminobenzotriazole and 1-aminobenzotriazole

n-benzyl-1-aminobenzotriazole has been researched along with 1-aminobenzotriazole in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bend, JR; Woodcroft, KJ1
Bend, JR; Grimm, SW; Halpert, JR1
Bend, JR; Knickle, LC; Philpot, RM1
Bend, JR; House, AA; Knickle, LC; Webb, CD1
Bend, JR; Webb, CD; Weedon, AC; Woodcroft, KJ; Yao, M1
Bend, JR; Moorthy, B; Parker, KM; Smith, CV; Welty, SE1

Other Studies

6 other study(ies) available for n-benzyl-1-aminobenzotriazole and 1-aminobenzotriazole

ArticleYear
N-aralkylated derivatives of 1-aminobenzotriazole as isozyme-selective, mechanism-based inhibitors of guinea pig hepatic cytochrome P-450 dependent monooxygenase activity.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:9

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Triazoles

1990
Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Activation; Humans; Isoenzymes; Kidney; Kinetics; Liver; Mice; Microsomes, Liver; Phenobarbital; Rabbits; Recombinant Proteins; Steroid Hydroxylases; Triazoles

1995
N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Guinea Pigs; Isoenzymes; Liver; Lung; Male; Phenobarbital; Sensitivity and Specificity; Triazoles

1994
Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Guinea Pigs; Kidney; Male; Microsomes; Microsomes, Liver; Oxidoreductases; Oxygenases; Triazoles

1993
Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Chemical research in toxicology, 1997, Volume: 10, Issue:5

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Lung; Male; Microsomes; Microsomes, Liver; Protein Binding; Triazoles

1997
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Animals; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Hyperoxia; Liver; Male; Microsomes; Oxazines; Oxygen; Pleural Effusion; Protein Isoforms; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Time Factors; Triazoles

2000