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n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione and amphetamine

n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione has been researched along with amphetamine in 1 studies

*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]

*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]

Compound Research Comparison

Studies
(n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione)
Trials
(n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione)
Recent Studies (post-2010)
(n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione)
Studies
(amphetamine)
Trials
(amphetamine)
Recent Studies (post-2010) (amphetamine)
70013,0713291,977

Protein Interaction Comparison

ProteinTaxonomyn-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione (IC50)amphetamine (IC50)
Phenylethanolamine N-methyltransferaseBos taurus (cattle)0.96
Cytochrome P450 2A6Homo sapiens (human)3.5
Cytochrome P450 2A5Mus musculus (house mouse)2.85
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.96
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.96

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beltcheva, I; Stoytchev, T1

Other Studies

1 other study(ies) available for n-aminomethylpiperazine 3,3-diethyl-2,4-pyridinedione and amphetamine

ArticleYear
Central depressive action of two N-aminomethyl derivatives of diethylpyridinedione.
    Acta physiologica et pharmacologica Bulgarica, 1983, Volume: 9, Issue:1

    Topics: Aggression; Amphetamine; Animals; Anticonvulsants; Humans; Male; Mice; Motor Activity; Pentylenetetrazole; Pyridones; Rats; Rats, Inbred Strains; Sleep

1983