n-acetyltyramine has been researched along with quinacrine in 2 studies
*Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2. [MeSH]
*Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2. [MeSH]
| Studies (n-acetyltyramine) | Trials (n-acetyltyramine) | Recent Studies (post-2010) (n-acetyltyramine) | Studies (quinacrine) | Trials (quinacrine) | Recent Studies (post-2010) (quinacrine) |
|---|---|---|---|---|---|
| 25 | 0 | 10 | 4,051 | 65 | 289 |
| Protein | Taxonomy | n-acetyltyramine (IC50) | quinacrine (IC50) |
|---|---|---|---|
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | 19.88 | |
| Major prion protein | Mus musculus (house mouse) | 0.0951 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.896 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.964 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.983 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.736 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.28 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 4.5 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.489 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 1.825 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.857 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.255 | |
| Acetylcholinesterase | Homo sapiens (human) | 2.667 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.896 | |
| Histamine H2 receptor | Homo sapiens (human) | 3.535 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 2.065 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.663 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.318 | |
| Aldehyde oxidase 1 | Oryctolagus cuniculus (rabbit) | 10 | |
| Cholinesterase | Equus caballus (horse) | 4.5 | |
| Aldehyde oxidase | Homo sapiens (human) | 3.3 | |
| Cyclic GMP-AMP synthase | Homo sapiens (human) | 7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
2 other study(ies) available for n-acetyltyramine and quinacrine
| Article | Year |
|---|---|
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |