n-acetyltryptophan and tryptophan

n-acetyltryptophan has been researched along with tryptophan in 82 studies

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199028 (34.15)18.7374
1990's7 (8.54)18.2507
2000's18 (21.95)29.6817
2010's25 (30.49)24.3611
2020's4 (4.88)2.80

Authors

AuthorsStudies
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H1
Hupe, D; Hupe, L; Johnson, LL; Nordan, I; Ye, QZ1
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H1
Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M1
Goldman, S; Henrottin, J; Laurent, S; Lemaire, C; Luxen, A; Plenevaux, A; Sapunaric, F; Van den Eynde, B; Zervosen, A1
Austin, JE; Fraenkel-Conrat, H1
Gaudemer, A; Mikros, E; Perrèe-Fauvet, M; Verchére-Bèaur, C1
Ashwood-Smith, MJ; Edwards, RG; Hollands, P1
Drozdz, R; Naskalski, JW; Sznajd, J1
Shechter, Y1
Bässler, KH; Musil, HE; Neuhäuser-Berthold, M; Schneider, R1
Narasimhan, S; Vithayathil, PJ1
Reuge, C1
Kuznetsova, IM; Turoverov, KK1
Baert, E; D'Hoore, W; De Leenheer, AP; Lefevere, MF; Nelis, HJ1
Muszkat, KA; Wismontski-Knittel, T1
Bridger, WH; Broderick, PA1
Finlayson, JS; Yu, MW2
Finlayson, JS; Ross, PD; Shrake, A2
Brown, GM; Burns, TG; Snieckus, V; Szechtman, H1
Brodersen, R; Ebbesen, F1
Doucet, D; Rambourg, P; Saint-Blancard, J1
Doucet, D; Labrude, P; Larcher, D; Le Graët, D; Rambourg, P; Saint-Blancard, J; Sévérac, P1
Anzai, M; Fujita, Y; Inoue, G; Inui, M; Nishimoto, T1
Endo, Y1
Hartman, RF; Kaptein, R; Pouwels, PJ; Rose, SD1
Craven, BM; He, XM1
Anderson, WL; Parikh, I; Shechter, Y1
Bazin, M; Mazière, JC; Morlière, P; Patterson, LK; Santus, R1
Fischer, L; Peissker, F1
Balny, C; Lange, R; Ruan, K; Tian, S1
Arakawa, T; Kita, Y1
Koch, TH; Meisenheimer, KM; Meisenheimer, PL1
Andrade, SM; Costa, SM1
de Groot, H; Fuchs, A; Kirsch, M1
Kierdaszuk, B; Włodarczyk, J1
COON, MJ; HOWE, EE; LAMBERT, GF; ROSE, WC1
EDMONDS, EJ; LANGNER, RR2
ERSPAMER, V; GLASSER, A; NOBILI, MB1
PUCHALSKI, C; SHAVEL, J; VONSTRANDTMANN, M1
Calhoun, LA; Embleton, J; King, RR; Lawrence, CH1
Friesen, MD; Gilibert, I; Mower, HF; Ohshima, H; Sawa, T; Suzuki, T1
Abdoul-Carime, H; Gohlke, S; Illenberger, E1
Anraku, M; Kragh-Hansen, U; Maruyama, T; Otagiri, M; Tsurusaki, Y; Watanabe, H1
Cernak, I; Cruz, MI; Donkin, JJ; Nimmo, AJ; Vink, R1
Kirsch, M; Lehnig, M1
Görner, H1
Kiryutin, AS; Morozova, OB; Yurkovskaya, AV1
ALBANESE, AA; DAVIS, VI; LEIN, M1
Blumbergs, PC; Cernak, I; Donkin, JJ; Nimmo, AJ; Vink, R1
Andersen, A; Kongsgaard, UE; Olsen, H; Reine, PA; Thøgersen, AK1
Akaike, T; Hiroyama, S; Ishima, Y; Kai, T; Kragh-Hansen, U; Maruyama, T; Otagiri, M; Sawa, T1
Helps, SC; Thornton, E; Turner, RJ; Vink, R1
Goetze, A; Gruenert, J; Klammt, S; Koball, S; Liebe, S; Mitzner, S; Reisinger, E; Stange, J; Stiffel, M; Strube, S1
Fang, L; Hu, P; Parti, R1
Thornton, E; Vink, R1
Carthew, HL; Vink, R; Ziebell, JM1
Guo, X; Hassanali, A; Kao, YT; Liu, Z; Song, QH; Wang, L; Yang, Y; Zhong, D1
Ghabriel, MN; Harford-Wright, E; Lewis, KM; Vink, R1
Lu, R; Yu, A; Yuan, S; Zhang, Y1
Corrigan, F; Hassall, MM; Thornton, E; Vink, R1
Anraku, M; Hirayama, F; Iohara, D; Ishima, Y; Kouno, Y; Kragh-Hansen, U; Maruyama, T; Okayama, Y; Otagiri, M; Yamasaki, K1
Daniel, AG; Farrell, NP; Ma, ES1
Leonard, AV; Thornton, E; Vink, R1
Turner, RJ; Vink, R1
Ivanov, KL; Pravdivtsev, AN; Vieth, HM; Yurkovskaya, AV1
Baranov, S; Chen, Y; Fotinos, A; Kristal, BS; Li, W; Sinha, B; Tu, Y; Wang, X; Wu, Q; Zhou, EW; Zhu, Y1
Friedlander, RM; Jiang, J; Li, W; Mao, LL; Sirianni, AC; Sugarbaker, P; Wang, X; Zeng, J; Zhang, X; Zhou, S1
Bernazar, L; Cañete, Á; Carathanassis, N; De la Fuente, JR; Díaz-Hernández, D; Saitz, C1
Sherin, PS; Sormacheva, ED; Tsentalovich, YP1
Arora, D; Basu Mallik, S; Fernandes, J; Mudgal, J; Nampoothiri, M; Pai, KSR; Rao, CM1
Baldassarre, M; Bartolini, M; Bertucci, C; Naldi, M; Tedesco, D; Tramarin, A1
Dion, MZ; Leiske, D; Salisbury, CM; Sharma, VK; Zuch de Zafra, CL1
Gulhar, R; Jialal, I; Shim, K1
Agarwal, P; Kumar, R; Raisuddin, S; Singh, D1
Chu, SH; Clish, C; Costenbader, KH; Cui, J; Deane, KD; Edison, JD; Feser, ML; Karlson, EW; Kelmenson, LB; Lasky-Su, J; Lu, B; Mewshaw, EA; Moss, L; Sparks, JA; Speyer, CB; Tedeschi, SK1
Bird, GH; Cohen, DT; Dhe-Paganon, S; Engen, JR; Guerra, RM; Harvey, EP; Hauseman, ZJ; Huhn, AJ; Lee, S; Luccarelli, J; Newman, CE; Rettenmaier, TJ; Seo, HS; Walensky, LD; Wales, TE; Wells, JA1
Chan, W; Chu, J; Doshi, N; Giddings, J; Graf, T; Hu, M; Kannan, A; Kei, P; Liu, W; Luis, L; Ritchie, K; Shieh, I; Sreedhara, A; Taing, R; Wu, A1

Trials

1 trial(s) available for n-acetyltryptophan and tryptophan

ArticleYear
Infusions of albumin increase free fraction of naproxen in healthy volunteers: a randomized crossover study.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:4

    Topics: Adult; Albumins; Anti-Inflammatory Agents, Non-Steroidal; Caprylates; Cross-Over Studies; Female; Half-Life; Humans; Immunohistochemistry; Indicators and Reagents; Infusions, Intravenous; Male; Middle Aged; Naproxen; Pharmaceutic Aids; Treatment Outcome; Tryptophan; Young Adult

2010

Other Studies

81 other study(ies) available for n-acetyltryptophan and tryptophan

ArticleYear
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste

1987
A recombinant human stromelysin catalytic domain identifying tryptophan derivatives as human stromelysin inhibitors.
    Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Catalysis; Escherichia coli; Humans; Matrix Metalloproteinase 3; Metalloendopeptidases; Molecular Sequence Data; Peptide Fragments; Recombinant Proteins; Tryptophan

1994
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
    Genomics, 2002, Volume: 79, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis

2002
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
    Nature chemical biology, 2009, Volume: 5, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction

2009
N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase.
    ACS medicinal chemistry letters, 2015, Mar-12, Volume: 6, Issue:3

    Topics:

2015
Tryptophan analogues form adducts by cooperative reaction with aldehydes and alcohols or with aldehydes alone: possible role in ethanol toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Sep-15, Volume: 89, Issue:18

    Topics: Acetaldehyde; Ethanol; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet; Tryptophan

1992
Structural studies of metalloporphyrins. Part XIa: Complexes of water-soluble zinc(II) porphyrins with amino acids: influence of ligand-ligand interactions on the stability of the complexes.
    Journal of inorganic biochemistry, 1990, Volume: 40, Issue:2

    Topics: Amino Acids; Anions; Cations; Chemical Phenomena; Chemistry, Physical; Drug Stability; Electrochemistry; Magnetic Resonance Spectroscopy; Metalloporphyrins; Molecular Structure; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine; Zinc

1990
The use of Albuminar 5 as a medium supplement in clinical IVF.
    Human reproduction (Oxford, England), 1989, Volume: 4, Issue:6

    Topics: Caprylates; Female; Fertilization in Vitro; Humans; Male; Serum Albumin; Tryptophan

1989
Action of myeloperoxidase-hydrogen peroxide-chloride system on the egg white lysozyme.
    Acta biochimica Polonica, 1988, Volume: 35, Issue:4

    Topics: Acetylcysteine; Chlorides; Cystine; Egg White; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Methionine; Muramidase; Peroxidase; Tryptophan

1988
Selective oxidation and reduction of methionine residues in peptides and proteins by oxygen exchange between sulfoxide and sulfide.
    The Journal of biological chemistry, 1986, Jan-05, Volume: 261, Issue:1

    Topics: Adrenocorticotropic Hormone; Chemical Phenomena; Chemistry; Chloramines; Dimethyl Sulfoxide; Hydrochloric Acid; Methionine; Oxidation-Reduction; Proteins; Spectrophotometry; Sulfides; Sulfoxides; Tosyl Compounds; Tryptophan

1986
[Evaluation of N-acetyl-L-tryptophan in long-term intravenous administration in growing rats].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:4

    Topics: Amino Acids; Animals; Body Weight; Long-Term Care; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Tryptophan

1988
A new reaction of o-benzoquinone with N-acetyl-DL-tryptophan (a 3-substituted indole) & characterisation of the product.
    Indian journal of biochemistry & biophysics, 1986, Volume: 23, Issue:4

    Topics: Benzoquinones; Chemical Phenomena; Chemistry; Quinones; Tryptophan

1986
[Determination of N-acetyl tryptophan in albumin solutions. Use of a F.P.L.C. method].
    Revue francaise de transfusion et immuno-hematologie, 1986, Volume: 29, Issue:6

    Topics: Albumins; Chromatography, High Pressure Liquid; Humans; Solutions; Tryptophan

1986
What causes the variation of polarization degree across the emission spectrum of proteins?
    Biophysical chemistry, 1986, Volume: 24, Issue:3

    Topics: Animals; Asparaginase; Dipeptides; Humans; Kinetics; Luminescent Measurements; Polarography; Proteins; Spectrometry, Fluorescence; Trypsin; Tryptophan

1986
Chromatographic determination of N-acetyl-DL-tryptophan and octanoic acid in human albumin solutions.
    Journal of chromatography, 1985, Oct-04, Volume: 333, Issue:2

    Topics: Albumins; Caprylates; Chromatography, Gas; Chromatography, Liquid; Drug Stability; Humans; Time Factors; Tryptophan

1985
Reactivities of tyrosine, histidine, tryptophan, and methionine in radical pair formation in flavin triplet induced protein nuclear magnetic polarization.
    Biochemistry, 1985, Sep-24, Volume: 24, Issue:20

    Topics: Flavins; Histidine; Kinetics; Magnetic Resonance Spectroscopy; Methionine; Oligopeptides; Photolysis; Proteins; Tryptophan; Tyrosine

1985
A comparative study of the effect of L-tryptophan and its acetylated derivative N-acetyl-L-tryptophan on rat muricidal behavior.
    Biological psychiatry, 1984, Volume: 19, Issue:1

    Topics: Aggression; Agonistic Behavior; Animals; Dose-Response Relationship, Drug; Humans; Male; Rats; Reaction Time; Tryptophan

1984
Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:1

    Topics: Albumins; Caprylates; Chromatography, Gas; Humans; Spectrophotometry, Ultraviolet; Tryptophan

1984
Thermal stability of human albumin measured by differential scanning calorimetry. II. Effects of isomers of N-acetyltryptophanate and tryptophanate, pH, reheating, and dimerization.
    Vox sanguinis, 1984, Volume: 47, Issue:1

    Topics: Calorimetry, Differential Scanning; Hot Temperature; Humans; Hydrogen-Ion Concentration; Protein Conformation; Protein Denaturation; Serum Albumin; Stereoisomerism; Tryptophan

1984
Stabilization of human albumin by caprylate and acetyltryptophanate.
    Vox sanguinis, 1984, Volume: 47, Issue:1

    Topics: Anions; Caprylates; Fatty Acids; Hot Temperature; Humans; Polymers; Protein Conformation; Protein Denaturation; Serum Albumin; Stereoisomerism; Tryptophan

1984
Thermal stability of human albumin measured by differential scanning calorimetry. I. Effects of caprylate and N-acetyltryptophanate.
    Vox sanguinis, 1984, Volume: 47, Issue:1

    Topics: Calorimetry, Differential Scanning; Caprylates; Fatty Acids; Hot Temperature; Humans; Protein Conformation; Protein Denaturation; Serum Albumin; Tryptophan

1984
Behavioral effects of 5-hydroxy-N-acetyltryptophan, a putative synthetic precursor of N-acetylserotonin.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:4-6

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1982
Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:1

    Topics: Bilirubin; Caprylates; Drug Stability; Female; Humans; Infant; Infant, Newborn; Jaundice, Neonatal; Male; Phototherapy; Serum Albumin; Tryptophan

1982
[Lyophilization protection of hemoglobin by N-acetyltryptophan].
    Revue francaise de transfusion et immuno-hematologie, 1982, Volume: 25, Issue:5

    Topics: Biological Transport; Blood Preservation; Desiccation; Freeze Drying; Glucose; Hemoglobins; Humans; Methemoglobin; Oxyhemoglobins; Tryptophan

1982
[Value of N-acetyltryptophan as a protector of hemoglobin during cryodesiccation].
    Annales pharmaceutiques francaises, 1982, Volume: 40, Issue:6

    Topics: Chemical Phenomena; Chemistry; Freeze Drying; Hemoglobins; Tryptophan

1982
Utilization of N-acetyl-L-tryptophan given intravenously to unrestrained adult rats.
    Journal of nutritional science and vitaminology, 1980, Volume: 26, Issue:4

    Topics: Adipose Tissue; Amino Acids; Animals; Injections, Intravenous; Male; Nitrogen; Rats; Tryptophan; Tryptophan Oxygenase

1980
In vivo deacetylation of N-acetyl amino acids by kidney acylases in mice and rats. A possible role of acylase system in mammalian kidneys.
    Biochimica et biophysica acta, 1980, Feb-21, Volume: 628, Issue:1

    Topics: Aging; Amidohydrolases; Animals; Histidine; Kidney; Kinetics; Liver; Mice; Rats; Tissue Distribution; Tryptophan

1980
Photo-CIDNP study of pyrimidine dimer splitting. II: Reactions involving pyrimidine radical anion intermediates.
    Photochemistry and photobiology, 1995, Volume: 61, Issue:6

    Topics: Anions; Chemical Phenomena; Chemistry, Physical; Free Radicals; Photochemistry; Photolysis; Photosensitizing Agents; Pyrimidine Dimers; Pyrimidines; Tryptophan

1995
Internal vibrations of a molecule consisting of rigid segments. I. Non-interacting internal vibrations.
    Acta crystallographica. Section A, Foundations of crystallography, 1993, Jan-01, Volume: 49 ( Pt 1)

    Topics: Adenosine; Benzamides; Chemical Phenomena; Chemistry, Physical; Hydrazines; Molecular Structure; Nitriles; Thermodynamics; Trinitrobenzenes; Tryptophan; X-Ray Diffraction

1993
Quantitation of methionyl peptides in nanomole quantities by a fluorometric method.
    Analytical biochemistry, 1978, Volume: 91, Issue:2

    Topics: Indicators and Reagents; Methionine; Oligopeptides; Peptides; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Tryptophan

1978
Intra and intermolecular charge effects on the reaction of the superoxide radical anion with semi-oxidized tryptophan in peptides and N-acetyl tryptophan.
    Free radical research, 1998, Volume: 29, Issue:5

    Topics: Amino Acid Sequence; Anions; Cetrimonium; Cetrimonium Compounds; DNA; Electrochemistry; Micelles; Oxidation-Reduction; Peptides; Pulse Radiolysis; Sodium Dodecyl Sulfate; Superoxides; Tryptophan

1998
Crosslinking of imprinted proteases to maintain a tailor-made substrate selectivity in aqueous solutions.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:10

    Topics: Chymotrypsin; Cross-Linking Reagents; Endopeptidases; Enzymes, Immobilized; Kinetics; Protease Inhibitors; Solutions; Substrate Specificity; Subtilisins; Tryptophan; Water

1999
Pressure effects on tryptophan and its derivatives.
    Biochemical and biophysical research communications, 2000, Mar-24, Volume: 269, Issue:3

    Topics: Ethanol; Glycerol; Hydrogen-Ion Concentration; Peptides; Pressure; Spectrometry, Fluorescence; Tryptophan

2000
Stabilizing effects of caprylate and acetyltryptophanate on heat-induced aggregation of bovine serum albumin.
    Biochimica et biophysica acta, 2000, Jun-15, Volume: 1479, Issue:1-2

    Topics: Animals; Caprylates; Cattle; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Serum Albumin, Bovine; Tryptophan

2000
Nucleoprotein photo-cross-linking using halopyrimidine-substituted RNAs.
    Methods in enzymology, 2000, Volume: 318

    Topics: Base Sequence; Bromouracil; Capsid; Capsid Proteins; Cross-Linking Reagents; Electrons; Electrophoresis, Polyacrylamide Gel; Kinetics; Models, Chemical; Molecular Sequence Data; Nucleic Acid Conformation; Nucleoproteins; Protein Binding; Pyrimidines; RNA; RNA-Binding Proteins; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays; Uridine; Water

2000
The location of tryptophan, N-acetyltryptophan and alpha-chymotrypsin in reverse micelles of AOT: a fluorescence study.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:4

    Topics: Animals; Cattle; Chymotrypsin; Dioctyl Sulfosuccinic Acid; Micelles; Spectrometry, Fluorescence; Surface-Active Agents; Tryptophan; Water

2000
Regiospecific nitrosation of N-terminal-blocked tryptophan derivatives by N2O3 at physiological pH.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Buffers; Cysteine; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitrogen Isotopes; Nitrogen Oxides; Nitrosation; Phosphates; S-Nitrosothiols; Tryptophan

2003
Interpretation of fluorescence decays using a power-like model.
    Biophysical journal, 2003, Volume: 85, Issue:1

    Topics: Computer Simulation; Fluorescence; Formycins; Half-Life; Light; Models, Chemical; Spectrometry, Fluorescence; Tryptophan; Tyrosine

2003
The amino acid requirements of man. VIII. The metabolic availability of the optical isomers of acetyltryptophan.
    The Journal of biological chemistry, 1955, Volume: 212, Issue:1

    Topics: Isomerism; Nitrogen; Tryptophan

1955
The digestion and absorption of acetyltryptophan.
    The Journal of biological chemistry, 1956, Volume: 223, Issue:1

    Topics: Digestion; Intestines; Tryptophan

1956
Absorption studies on tryptophan and acetyltryptophan.
    The Journal of biological chemistry, 1956, Volume: 223, Issue:1

    Topics: Gastrointestinal Tract; Research; Tryptophan

1956
The fate of 5-hydroxy-N-acetyltryptophan and 5-acetoxy-N-acetyltryptophan in the rat organism.
    Archives of biochemistry and biophysics, 1961, Volume: 93

    Topics: 5-Hydroxytryptophan; Animals; Rats; Tryptophan

1961
ACYLTRYPTAMINES. 3. 5-ACETYLTRYPTOPHAN AND RELATED COMPOUNDS.
    Journal of medicinal chemistry, 1964, Volume: 7

    Topics: Antihypertensive Agents; Blood Pressure; Chemistry, Pharmaceutical; Dogs; Indoles; Pharmacology; Research; Tryptamines; Tryptophan

1964
More chemistry of the thaxtomin phytotoxins.
    Phytochemistry, 2003, Volume: 64, Issue:6

    Topics: Bacterial Toxins; Indoles; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Piperazines; Streptomyces; Tryptophan

2003
Nitration and nitrosation of N-acetyl-L-tryptophan and tryptophan residues in proteins by various reactive nitrogen species.
    Free radical biology & medicine, 2004, Sep-01, Volume: 37, Issue:5

    Topics: Chromatography, High Pressure Liquid; Nitrates; Nitrosation; Nitroso Compounds; Peroxynitrous Acid; Proteins; Reactive Nitrogen Species; Tryptophan

2004
Degradation of N-acetyl tryptophan by low-energy (<12 eV) electrons.
    Journal of the American Chemical Society, 2004, Sep-29, Volume: 126, Issue:38

    Topics: Electrons; Proteins; Radiobiology; Tryptophan

2004
Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress.
    Biochimica et biophysica acta, 2004, Oct-01, Volume: 1702, Issue:1

    Topics: Calorimetry, Differential Scanning; Caprylates; Circular Dichroism; Drug Stability; Hot Temperature; Humans; In Vitro Techniques; Ligands; Oxidation-Reduction; Oxidative Stress; Serum Albumin; Tryptophan

2004
A substance P antagonist increases brain intracellular free magnesium concentration after diffuse traumatic brain injury in rats.
    Journal of the American College of Nutrition, 2004, Volume: 23, Issue:5

    Topics: Animals; Brain Injuries; Homeostasis; Magnesium; Magnesium Deficiency; Magnetic Resonance Spectroscopy; Male; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Substance P; Tryptophan

2004
15N-CIDNP investigations during tryptophan, N-acetyl-L-tryptophan, and melatonin nitration with reactive nitrogen species.
    Free radical research, 2007, Volume: 41, Issue:5

    Topics: Magnetic Resonance Spectroscopy; Melatonin; Molecular Structure; Nitrates; Nitrogen; Peroxynitrous Acid; Photochemistry; Reactive Nitrogen Species; Tryptophan

2007
Electron transfer from aromatic amino acids to triplet quinones.
    Journal of photochemistry and photobiology. B, Biology, 2007, Sep-25, Volume: 88, Issue:2-3

    Topics: Amino Acids, Aromatic; Anthraquinones; Benzoquinones; Electron Transport; Free Radicals; Halogens; Hydrogen Peroxide; Indoles; Kinetics; Methylation; Naphthoquinones; Oxidation-Reduction; Oxygen; Quinones; Spectrum Analysis; Tryptophan; Tyrosine; Ultraviolet Rays

2007
Electron transfer between guanosine radicals and amino acids in aqueous solution. II. Reduction of guanosine radicals by tryptophan.
    The journal of physical chemistry. B, 2008, Mar-06, Volume: 112, Issue:9

    Topics: 2,2'-Dipyridyl; Algorithms; Electron Transport; Free Radicals; Guanosine; Guanosine Monophosphate; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Photochemistry; Protons; Tryptophan

2008
The utilization of d-amino acids by man; tryptophan and acetyltryptophan.
    The Journal of biological chemistry, 1948, Volume: 172, Issue:1

    Topics: Amino Acids; Antifibrinolytic Agents; Humans; Tryptophan

1948
Substance P is associated with the development of brain edema and functional deficits after traumatic brain injury.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:8

    Topics: Animals; Brain Edema; Brain Injuries; Capillary Permeability; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Magnetic Resonance Imaging; Male; Microscopy, Confocal; Microscopy, Immunoelectron; Motor Activity; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Substance P; Tryptophan

2009
One-step preparation of S-nitrosated human serum albumin with high biological activities.
    Nitric oxide : biology and chemistry, 2010, Sep-15, Volume: 23, Issue:2

    Topics: Animals; Blotting, Western; Caprylates; Circular Dichroism; Cysteine; Cytoprotection; Humans; Liver; Nitric Oxide; Nitrosation; Nitroso Compounds; Oxidation-Reduction; Rats; Reperfusion Injury; S-Nitrosoglutathione; Serum Albumin; Serum Albumin, Human; Sulfhydryl Reagents; Time Factors; Tryptophan

2010
A substance P antagonist improves outcome when administered 4 h after onset of ischaemic stroke.
    Brain research, 2011, Jun-01, Volume: 1393

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Disease Models, Animal; Drug Administration Schedule; Infarction, Middle Cerebral Artery; Male; Neurokinin-1 Receptor Antagonists; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Recovery of Function; Substance P; Time Factors; Tryptophan

2011
Industrial stabilizers caprylate and N-acetyltryptophanate reduce the efficacy of albumin in liver patients.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2011, Volume: 17, Issue:6

    Topics: Aged; Albumins; Blood Volume; Caprylates; Charcoal; Feasibility Studies; Female; Humans; Hypertension, Portal; Infusions, Intravenous; Kidney; Liver Cirrhosis; Male; Middle Aged; Pilot Projects; Treatment Outcome; Tryptophan

2011
Characterization of N-acetyltryptophan degradation products in concentrated human serum albumin solutions and development of an automated high performance liquid chromatography-mass spectrometry method for their quantitation.
    Journal of chromatography. A, 2011, Oct-14, Volume: 1218, Issue:41

    Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Indoles; Reproducibility of Results; Sensitivity and Specificity; Serum Albumin; Tryptophan

2011
Treatment with a substance P receptor antagonist is neuroprotective in the intrastriatal 6-hydroxydopamine model of early Parkinson's disease.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Cells; Dopaminergic Neurons; Inflammation; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Substance P; Substantia Nigra; Tryptophan

2012
Substance P-induced changes in cell genesis following diffuse traumatic brain injury.
    Neuroscience, 2012, Jul-12, Volume: 214

    Topics: Animals; Brain Injuries; Cell Differentiation; Male; Microglia; Neurogenesis; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Tryptophan

2012
Ultrafast dynamics of nonequilibrium electron transfer in photoinduced redox cycle: solvent mediation and conformation flexibility.
    The journal of physical chemistry. B, 2012, Aug-02, Volume: 116, Issue:30

    Topics: Acetonitriles; Dioxanes; Electron Transport; Oxidation-Reduction; Solvents; Thymine; Time Factors; Tryptophan; Water

2012
NK1 receptor antagonists and dexamethasone as anticancer agents in vitro and in a model of brain tumours secondary to breast cancer.
    Anti-cancer drugs, 2013, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Astrocytes; Brain Edema; Brain Neoplasms; Calcium-Binding Proteins; Carcinoma; Cell Line, Tumor; Corpus Striatum; Dexamethasone; Drug Screening Assays, Antitumor; Female; Glial Fibrillary Acidic Protein; Humans; In Vitro Techniques; Male; Mammary Neoplasms, Experimental; Microfilament Proteins; Microglia; Models, Biological; Morpholines; Neoplasm Proteins; Neurokinin-1 Receptor Antagonists; Random Allocation; Rats; Rats, Wistar; Receptors, Neurokinin-1; Tryptophan; Tumor Burden; Tumor Microenvironment

2013
Ultrafast fluorescence quenching dynamics of Atto655 in the presence of N-acetyltyrosine and N-acetyltryptophan in aqueous solution: proton-coupled electron transfer versus electron transfer.
    The journal of physical chemistry. B, 2013, Jun-20, Volume: 117, Issue:24

    Topics: Electron Transport; Electrons; Fluorescence; Fluorescent Dyes; Heterocyclic Compounds, 4 or More Rings; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Molecular Structure; Proflavine; Protons; Solutions; Tryptophan; Tyrosine; Water

2013
The NK1 receptor antagonist N-acetyl-L-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:5

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Time Factors; Tryptophan; Tyrosine 3-Monooxygenase

2014
N-acetyl-l-methionine is a superior protectant of human serum albumin against photo-oxidation and reactive oxygen species compared to N-acetyl-L-tryptophan.
    Biochimica et biophysica acta, 2014, Volume: 1840, Issue:9

    Topics: Free Radical Scavengers; Humans; Methionine; Oxidation-Reduction; Photochemical Processes; Protein Stability; Reactive Oxygen Species; Serum Albumin; Tryptophan

2014
Dinuclear platinum complexes containing planar aromatic ligands to enhance stacking interactions with proteins.
    ChemMedChem, 2014, Volume: 9, Issue:6

    Topics: Amino Acid Sequence; Benzothiazoles; Cell Line, Tumor; Cell Survival; Coordination Complexes; Humans; Kinetics; Ligands; Models, Molecular; Peptides; Platinum; Protein Binding; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Quinolines; Tryptophan; Tumor Suppressor Protein p53

2014
NK1 receptor blockade is ineffective in improving outcome following a balloon compression model of spinal cord injury.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Inflammation; Neurokinin-1 Receptor Antagonists; Protease Inhibitors; Rabbits; Receptors, Neurokinin-1; Spinal Cord Compression; Substance P; Tryptophan

2014
NK1 tachykinin receptor treatment is superior to capsaicin pre-treatment in improving functional outcome following acute ischemic stroke.
    Neuropeptides, 2014, Volume: 48, Issue:5

    Topics: Animals; Capsaicin; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Recovery of Function; Reperfusion Injury; Rotarod Performance Test; Stroke; Tryptophan

2014
Importance of polarization transfer in reaction products for interpreting and analyzing CIDNP at low magnetic fields.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2015, Volume: 254

    Topics: Amino Acids; Electromagnetic Fields; Histidine; Indicators and Reagents; Lasers; Magnetic Resonance Spectroscopy; Spin Labels; Tryptophan; Tyrosine

2015
N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.
    Neurobiology of disease, 2015, Volume: 80

    Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Male; Mice; Mice, Transgenic; Mitochondria; Motor Neurons; Neuroglia; Receptors, Neurokinin-1; Spinal Cord; Superoxide Dismutase; Survival Analysis; Tryptophan

2015
N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2015, Volume: 134, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Caspases; Cell Line; Cytochromes c; Drug Evaluation, Preclinical; Hybrid Cells; Interleukin-1beta; Mice; Mitochondria; Motor Neurons; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Proteasome Endopeptidase Complex; Receptors, Neurokinin-1; Stereoisomerism; Substance P; Tryptophan

2015
Spectral and Kinetic Study of 3-Methylquinoxalin-2-ones Photoreduced by Amino Acids: N-Phenylglycine Radical Chain Reactions and N-Acetyltryptophan Decarboxylation.
    The journal of physical chemistry. A, 2016, 05-12, Volume: 120, Issue:18

    Topics: Amino Acids; Decarboxylation; Glycine; Ketones; Kinetics; Light; Oxidation-Reduction; Quinoxalines; Tryptophan

2016
Dimerization and oxidation of tryptophan in UV-A photolysis sensitized by kynurenic acid.
    Free radical biology & medicine, 2017, Volume: 113

    Topics: alpha-Crystallins; Animals; Cattle; Chemical Fractionation; Dimerization; Electron Transport; Kynurenic Acid; Lens, Crystalline; Oxidation-Reduction; Oxygen; Photolysis; Photosensitizing Agents; Singlet Oxygen; Superoxides; Tryptophan; Ultraviolet Rays

2017
N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:5

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Apoptosis; Behavior, Animal; Brain; Chlorides; Disease Models, Animal; Glutathione; GPI-Linked Proteins; Male; Maze Learning; Memory Disorders; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Spatial Memory; Time Factors; Tryptophan

2018
New insights into the altered binding capacity of pharmaceutical-grade human serum albumin: site-specific binding studies by induced circular dichroism spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162

    Topics: Binding Sites; Caprylates; Chemistry, Pharmaceutical; Circular Dichroism; Dialysis; Hydrogen-Ion Concentration; Protein Binding; Protein Conformation; Protein Stability; Protein Unfolding; Serum Albumin, Human; Structure-Activity Relationship; Tryptophan; Ultrafiltration

2019
Mitigation of Oxidation in Therapeutic Antibody Formulations: a Biochemical Efficacy and Safety Evaluation of N-Acetyl-Tryptophan and L-Methionine.
    Pharmaceutical research, 2018, Oct-02, Volume: 35, Issue:11

    Topics: Amidines; Animals; Antibodies, Monoclonal; Antioxidants; Biological Products; Cell Line, Tumor; Computer Simulation; Drug Compounding; Excipients; Female; Humans; Macaca fascicularis; Male; Methionine; Mutagenicity Tests; Oxidation-Reduction; Protein Conformation; Protein Stability; Rabbits; Tryptophan; Ultraviolet Rays

2018
Exploratory metabolomics of nascent metabolic syndrome.
    Journal of diabetes and its complications, 2019, Volume: 33, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Female; gamma-Aminobutyric Acid; Humans; Inflammation; Male; Metabolic Syndrome; Metabolomics; Middle Aged; Pyrrolidonecarboxylic Acid; Triglycerides; Tryptophan; Waist Circumference

2019
Amelioration of ochratoxin-A induced cytotoxicity by prophylactic treatment of N-Acetyl-L-Tryptophan in human embryonic kidney cells.
    Toxicology, 2020, 01-15, Volume: 429

    Topics: Apoptosis; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Kidney; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Ochratoxins; Oxidative Stress; Tryptophan

2020
Circulating plasma metabolites and risk of rheumatoid arthritis in the Nurses' Health Study.
    Rheumatology (Oxford, England), 2020, 11-01, Volume: 59, Issue:11

    Topics: Adult; Age Factors; Arthritis, Rheumatoid; Body Mass Index; Butyric Acid; Caprylates; Carnitine; Case-Control Studies; Female; Humans; Incidence; Logistic Models; Metabolome; Methionine; Middle Aged; Military Personnel; Nurses; Phosphatidylethanolamines; Prospective Studies; Putrescine; Reproducibility of Results; Risk Factors; Smoking; Spermidine; Tryptophan; United States

2020
Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
    Cell chemical biology, 2020, 06-18, Volume: 27, Issue:6

    Topics: Apoptosis; Disulfides; Dose-Response Relationship, Drug; Humans; Minor Histocompatibility Antigens; Models, Molecular; Molecular Structure; Peptides; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Tryptophan

2020
A Comprehensive Assessment of All-Oleate Polysorbate 80: Free Fatty Acid Particle Formation, Interfacial Protection and Oxidative Degradation.
    Pharmaceutical research, 2021, Volume: 38, Issue:3

    Topics: Antibodies, Monoclonal; Drug Carriers; Drug Compounding; Drug Stability; Fatty Acids, Nonesterified; Hydrolysis; Methionine; Oleic Acid; Oxidation-Reduction; Oxidative Stress; Particle Size; Polysorbates; Tryptophan

2021