n-acetylsphingosine has been researched along with staurosporine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deli, E; Kiss, Z | 1 |
| Hunchuk, N; Li, XB; Wong, K | 1 |
| Dawson, G; Wiesner, DA | 1 |
| Bredesen, DE; Foster, LM; Kayalar, C; Keane, RW; Nonner, D; Ord, T; Reed, JC; Srinivasan, A; Testa, MP; Wang, HG | 1 |
| Igarashi, Y; Nishiyama, K; Ohi, Y; Ozawa, M; Sakakura, C; Shirahama, T; Sweeney, EA; Takemoto, M | 1 |
| Baker, A; Briehl, MM; Payne, CM; Powis, G | 1 |
| Patel, M | 1 |
| Clift, RE; Reiners, JJ | 1 |
| Boustany, RM; Guo, WX; Nikbakht, K; Puranam, KL; Qian, WH | 1 |
| Askew, DJ; Brunner, T; Green, DR; Kuscuoglu, U; Miesfeld, RL | 1 |
| Cho, S; Dawson, G; Dawson, PE | 1 |
| Choi, DW; Goldberg, MP; Hyrc, K; Sheline, C; Wang, XQ; Xiao, AY; Yang, A; Yu, SP | 1 |
| Dawson, G; Dawson, SA; Moskal, JR | 1 |
| Dawson, G; Goswami, R; Kilkus, J; Phillips, G; Singh, D | 1 |
| Altevogt, P; Gast, D; Gutwein, P; Issa, Y; Sanderson, MP; Stoeck, A | 1 |
| Hanck, T; Li, R; Reiser, G; Rohatgi, T | 1 |
| Furuchi, T; Homma, H; Katane, M; Sekine, M; Suzuki, T | 1 |
| Li, R; Reiser, G | 1 |
| Li, R; Reiser, G; Zhu, Z | 1 |
| Faden, AI; Hanscom, M; Piao, CS; Sabirzhanov, B; Stoica, BA | 1 |
| Ford, AL; Gonzales, E; Holtzman, DM; Lee, JM; Lee, KY; West, T; Xiao, Q; Xu, J; Yan, P | 1 |
| Doyle, A; Leanza, L; O'Reilly, P; Szabo, I; Szegezdi, E; Venturini, E; Zoratti, M | 1 |
| Li, R; Reiser, G; Stricker, R; Zhu, Z | 1 |
23 other study(ies) available for n-acetylsphingosine and staurosporine
| Article | Year |
|---|---|
Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Bryostatins; Down-Regulation; Drug Interactions; Ethers, Cyclic; Hydrolysis; Lactones; Macrolides; Mice; Okadaic Acid; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Protein Kinase C; Sphingomyelin Phosphodiesterase; Sphingosine; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
N-acetylsphingosine (C2-ceramide) inhibited neutrophil superoxide formation and calcium influx.
Topics: Alkaloids; Biological Transport, Active; Blood Proteins; Calcium; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Spectrometry, Fluorescence; Sphingosine; Staurosporine; Superoxides | 1995 |
Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway.
Topics: Alkaloids; Animals; Apoptosis; Cells, Cultured; Ceramides; Chick Embryo; DNA Damage; Enzyme Inhibitors; Neurons; Protein Kinase C; Sphingomyelins; Sphingosine; Staurosporine; Time Factors | 1996 |
Activation of CPP32 during apoptosis of neurons and astrocytes.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Astrocytes; Bisbenzimidazole; Caspase 3; Caspases; Cell-Free System; Cells, Cultured; Culture Media, Serum-Free; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Mice; Mice, Inbred Strains; Neurons; Poly(ADP-ribose) Polymerases; Sphingosine; Staurosporine | 1997 |
Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression.
Topics: Androgens; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Male; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Staurosporine | 1997 |
Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo.
Topics: Animals; Apoptosis; Dexamethasone; DNA, Complementary; Enzyme Inhibitors; Humans; Mice; Mice, SCID; Neoplasm Proteins; Sphingosine; Staurosporine; Thapsigargin; Thioredoxins; Transfection; Tumor Cells, Cultured | 1997 |
Inhibition of neuronal apoptosis by a metalloporphyrin superoxide dismutase mimic.
Topics: Animals; Apoptosis; Astrocytes; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Free Radical Scavengers; Metalloporphyrins; Neurons; Rats; Sphingosine; Staurosporine; Superoxide Dismutase | 1998 |
Aryl hydrocarbon receptor regulation of ceramide-induced apoptosis in murine hepatoma 1c1c7 cells. A function independent of aryl hydrocarbon receptor nuclear translocator.
Topics: Animals; Apoptosis; Aryl Hydrocarbon Receptor Nuclear Translocator; DNA-Binding Proteins; Doxorubicin; Liver Neoplasms, Experimental; Mice; Receptors, Aryl Hydrocarbon; Sphingosine; Staurosporine; Transcription Factors; Tumor Cells, Cultured | 1999 |
CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide.
Topics: Apoptosis; Blotting, Western; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Ceramides; Cyclins; Dose-Response Relationship, Drug; Etoposide; Humans; Membrane Glycoproteins; Models, Biological; Molecular Chaperones; Neurodegenerative Diseases; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Sphingosine; Staurosporine; Time Factors; Transfection; Vincristine | 1999 |
Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis.
Topics: Animals; Apoptosis; Caspases; Dexamethasone; Enzyme Inhibitors; fas Receptor; Glucocorticoids; Humans; Mice; Mutagenesis; Sphingosine; Staurosporine; Tumor Cells, Cultured | 1999 |
Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Chromones; Daunorubicin; Enzyme Inhibitors; Etoposide; Humans; Infant; Morpholines; Nerve Degeneration; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Neurons; Nucleic Acid Synthesis Inhibitors; Sphingosine; Staurosporine; Thiolester Hydrolases; Transfection; Tumor Cells, Cultured | 2001 |
Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Intracellular Membranes; Membrane Potentials; Mice; Microscopy, Confocal; Mitochondria; Neurons; Oxidative Stress; Phosphorylation; Precipitin Tests; Pyruvic Acid; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Sphingosine; Staurosporine; Succinic Acid; Time Factors | 2003 |
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death.
Topics: Antineoplastic Agents; beta-D-Galactoside alpha 2-6-Sialyltransferase; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Glioma; Glycoconjugates; Glycosylation; Humans; Morpholines; N-Acetylglucosaminyltransferases; Oligosaccharides; Sialyltransferases; Sphingosine; Staurosporine; Transfection | 2004 |
Ceramide regulation of the tumor suppressor phosphatase PTEN in rafts isolated from neurotumor cell lines.
Topics: Androstadienes; Animals; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 8; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Membrane Microdomains; Oligodendroglioma; PC12 Cells; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Rats; Sphingosine; Staurosporine; Transfection; Tumor Suppressor Proteins; Wortmannin | 2005 |
L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.
Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Female; Humans; Neural Cell Adhesion Molecule L1; Ovarian Neoplasms; Sphingosine; Staurosporine; Transfection | 2007 |
Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death.
Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Animals; Astrocytes; Cell Death; Cell Line; Cells, Cultured; Humans; Immunoprecipitation; Insecta; Protein Binding; Rats; Receptor, PAR-2; Sphingosine; Staurosporine | 2009 |
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells.
Topics: Animals; Apoptosis; Aspartic Acid; Calcimycin; Hydrogen Peroxide; Hypotonic Solutions; Ion Channels; Ionophores; Nitrobenzoates; PC12 Cells; Rats; Sphingosine; Staurosporine; Stereoisomerism; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uric Acid | 2009 |
Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death.
Topics: alpha-Crystallin B Chain; Animals; Astrocytes; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sphingosine; Staurosporine | 2011 |
Specific phosphorylation of αA-crystallin is required for the αA-crystallin-induced protection of astrocytes against staurosporine and C2-ceramide toxicity.
Topics: alpha-Crystallin A Chain; Animals; Astrocytes; Cell Survival; Phosphorylation; Primary Cell Culture; Rats; Rats, Wistar; Sphingosine; Staurosporine | 2012 |
Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Etoposide; Gene Expression Regulation; Green Fluorescent Proteins; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Neural Inhibition; Neuroblastoma; Neurons; Peptide Fragments; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Binding; Rats; Signal Transduction; Sphingosine; Staurosporine; Transfection | 2012 |
Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.
Topics: Alternative Splicing; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; bcl-X Protein; Brain Injuries; CELF1 Protein; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Functional Laterality; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Male; Mice; Neurons; Pregnancy; Rats; RNA Precursors; RNA-Binding Proteins; RNA, Small Interfering; Sphingosine; Staurosporine; Time Factors; Transfection | 2012 |
Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines.
Topics: Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cisplatin; Gene Expression Regulation, Neoplastic; Humans; Kv1.1 Potassium Channel; Kv1.3 Potassium Channel; Mitochondria; Neoplasms; Potassium Channel Blockers; RNA, Messenger; Sphingosine; Staurosporine; Tumor Burden | 2014 |
Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria.
Topics: alpha-Crystallins; Animals; Antimycin A; Astrocytes; Brain; Cell Death; Cell Survival; Cells, Cultured; Escherichia coli; Extracellular Space; MAP Kinase Signaling System; Mitochondria; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Sphingosine; Staurosporine; TOR Serine-Threonine Kinases | 2015 |