n-acetylsphingosine and sphingosine 1-phosphate

n-acetylsphingosine has been researched along with sphingosine 1-phosphate in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (50.00)18.2507
2000's8 (33.33)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Farach-Carson, MC; Karin, NJ; Liu, R1
Coso, OA; Cuvillier, O; Gutkind, S; Kleuser, B; Pirianov, G; Spiegel, S; Vanek, PG1
Igarashi, Y; Nishiyama, K; Ohi, Y; Ozawa, M; Sakakura, C; Shirahama, T; Sweeney, EA; Takemoto, M1
Kaida, T; Kozawa, O; Suzuki, A; Tokuda, H; Uematsu, T1
Cuvillier, O; Rosenthal, DS; Smulson, ME; Spiegel, S1
Hanazawa, S; Ishida, M; Kitano, S; Ozaki, K; Takeda, H; Yasuda, H1
Csaba, G; Kovács, P; Müller, WE1
Barter, PJ; Bert, AG; Cockerill, P; Gamble, JR; Hii, CS; Khew-Goodall, Y; Rye, KA; Vadas, MA; Wang, L; Xia, P1
Kikuchi, S; Moriwaka, F; Shinpo, K; Tashiro, K1
Akimoto, S; Fujino, MA; Hisano, N; Mitsumata, M; Ozaki, Y; Satoh, K; Yatomi, Y1
Dallalio, G; Means, RT; North, M; Worden, BD1
Cuvillier, O; Edsall, L; Kohama, T; Nava, V; Olivera, A; Poulton, S; Spiegel, S1
Channing, DR; Nahorski, SR; Young, KW1
Chung, JH; Eun, HC; Kim, DS; Kim, KH; Kim, SY; Park, KC1
Bhadra, R; Mallick, S; Mandal, SK1
Hatakeyama, D; Kozawa, O; Matsuno, H; Oiso, Y; Tokuda, H; Uematsu, T1
Igarashi, Y; Okazaki, T; Taguchi, Y; Tomimoto, H; Yabu, T; Yamaoka, S1
Boggaram, V; Chandru, H; Sparkman, L1
Chen, YC; Chien, CC; Liau, JS; Shen, SC; Wu, CY; Yang, LY1
Nicol, GD1
Abrahan, CE; Agnolazza, DL; Miranda, GE; Politi, LE; Rotstein, NP1
Asano, S; Hashimoto-Nishimura, M; Hayashi, A; Igarashi, Y; Kigawa, J; Kitatani, K; Kondo, T; Mitsutake, S; Okazaki, T; Takeya, H; Taniguchi, M; Umehara, H1
Chen, L; Geng, X; Guo, L; Li, H; Luo, C; Ma, L; Ou, X; Quan, S; Zeng, W1
Ayub, M; Bae, JS; Jin, HK1

Reviews

1 review(s) available for n-acetylsphingosine and sphingosine 1-phosphate

ArticleYear
Novelty of Sphingolipids in the Central Nervous System Physiology and Disease: Focusing on the Sphingolipid Hypothesis of Neuroinflammation and Neurodegeneration.
    International journal of molecular sciences, 2021, Jul-08, Volume: 22, Issue:14

    Topics: Alzheimer Disease; Central Nervous System; Ceramides; Eicosanoids; Forecasting; Homeostasis; Humans; Inflammation; Lipoxygenase; Lysophospholipids; Membrane Lipids; Models, Biological; Nerve Degeneration; Neurodegenerative Diseases; Neuroglia; Neurons; Parkinson Disease; Phosphotransferases (Alcohol Group Acceptor); Prostaglandin-Endoperoxide Synthases; Sphingolipids; Sphingosine

2021

Other Studies

23 other study(ies) available for n-acetylsphingosine and sphingosine 1-phosphate

ArticleYear
Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellualr stores.
    Biochemical and biophysical research communications, 1995, Sep-14, Volume: 214, Issue:2

    Topics: 3T3 Cells; Animals; Calcium; Fluorescent Dyes; Fura-2; Kinetics; Lysophospholipids; Mice; Osteoblasts; Phosphorylation; Phosphorylcholine; Psychosine; Sphingosine; Structure-Activity Relationship

1995
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate.
    Nature, 1996, Jun-27, Volume: 381, Issue:6585

    Topics: 3T3 Cells; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Ceramides; DNA Damage; Enzyme Activation; fas Receptor; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Signal Transduction; Sphingosine; Tumor Necrosis Factor-alpha

1996
Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression.
    FEBS letters, 1997, Apr-21, Volume: 407, Issue:1

    Topics: Androgens; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Male; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Staurosporine

1997
Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C.
    The Journal of biological chemistry, 1997, Oct-03, Volume: 272, Issue:40

    Topics: 3T3 Cells; Animals; Bridged-Ring Compounds; Choline; Diglycerides; Enzyme Activation; Homeostasis; Inositol Phosphates; Interleukin-6; Kinetics; Lysophospholipids; Mice; Norbornanes; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorylcholine; Protein Kinase C; Sphingosine; Thiocarbamates; Thiones; Tumor Necrosis Factor-alpha; Type C Phospholipases

1997
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes.
    The Journal of biological chemistry, 1998, Jan-30, Volume: 273, Issue:5

    Topics: Apoptosis; Caspase 3; Caspase 6; Caspase 7; Caspases; Cysteine Endopeptidases; Enzyme Activation; fas Receptor; Humans; Jurkat Cells; Lamin Type B; Lamins; Lysophospholipids; Models, Biological; Nuclear Proteins; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sphingosine; T-Lymphocytes; Tetradecanoylphorbol Acetate

1998
Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts.
    FEBS letters, 1998, Jan-30, Volume: 422, Issue:2

    Topics: Actins; Animals; Animals, Newborn; Apoptosis; Bone Resorption; Cells, Cultured; Enzyme Inhibitors; Lysophospholipids; Osteoclasts; Rabbits; Sphingomyelin Phosphodiesterase; Sphingosine

1998
The effects of ceramide and its analogues on the secretion of the mucocyst content of Tetrahymena.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Ceramides; Dibucaine; Female; Fluorescence; Lectins; Lysophospholipids; Mice; Mice, Inbred BALB C; Porifera; Psychosine; Sphingomyelins; Sphingosine; Tetrahymena pyriformis

1998
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Nov-24, Volume: 95, Issue:24

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; E-Selectin; Endothelium, Vascular; Enzyme Activation; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Lysophospholipids; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingomyelins; Sphingosine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1

1998
Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons.
    Brain research, 1999, Feb-20, Volume: 819, Issue:1-2

    Topics: Animals; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Lysophospholipids; Mesencephalon; Neurons; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Time Factors; Tumor Necrosis Factor-alpha

1999
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells.
    Blood, 1999, Jun-15, Volume: 93, Issue:12

    Topics: Acetic Anhydrides; Acylation; Apoptosis; Blood Platelets; Cell Communication; DNA; Endothelium, Vascular; Humans; Lysophospholipids; Microscopy, Fluorescence; Sphingolipids; Sphingosine; Umbilical Veins

1999
Inhibition of human erythroid colony formation by ceramide.
    Experimental hematology, 1999, Volume: 27, Issue:7

    Topics: Apoptosis; Ceramides; Colony-Forming Units Assay; Depression, Chemical; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; fas Receptor; Humans; Interferon-beta; Interferon-gamma; Lysophospholipids; Recombinant Proteins; Sphingomyelin Phosphodiesterase; Sphingosine

1999
Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.
    The Journal of cell biology, 1999, Nov-01, Volume: 147, Issue:3

    Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Division; Cell Line; Cell Survival; Cytosol; DNA; Enzyme Activation; fas Receptor; Humans; Lysophospholipids; Mice; Peptide Hydrolases; Pertussis Toxin; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Recombinant Fusion Proteins; Second Messenger Systems; Sphingosine; Transfection; Virulence Factors, Bordetella

1999
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells.
    European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2

    Topics: Brain Neoplasms; Calcium; Cell Line; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Methacholine Chloride; Muscarinic Agonists; N-Methylscopolamine; Neuroblastoma; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Sphingosine

2000
Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes.
    Cellular signalling, 2002, Volume: 14, Issue:9

    Topics: Adolescent; Cells, Cultured; Chromones; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Lysophospholipids; Melanins; Melanocytes; Microphthalmia-Associated Transcription Factor; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monophenol Monooxygenase; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrones; Sphingosine; Transcription Factors

2002
Human placental lipid induces mitogenesis and melanogenesis in B16F10 melanoma cells.
    Journal of biosciences, 2002, Volume: 27, Issue:3

    Topics: Animals; Cell Division; Cell Size; Cell Survival; Humans; Lipids; Lysophospholipids; Melanins; Melanoma; Mice; Placental Extracts; Sphingolipids; Sphingosine; Tumor Cells, Cultured

2002
Sphingomyelinase amplifies BMP-4-induced osteocalcin synthesis in osteoblasts: role of ceramide.
    Cellular signalling, 2002, Volume: 14, Issue:12

    Topics: Amidohydrolases; Animals; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Cell Line; Ceramidases; Ceramides; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Lysophospholipids; Mice; Mitogen-Activated Protein Kinases; Myristates; Osteoblasts; Osteocalcin; Phosphorylation; Propanolamines; Smad Proteins; Smad1 Protein; Sphingomyelin Phosphodiesterase; Sphingosine; Trans-Activators

2002
Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate.
    Blood, 2005, Jul-01, Volume: 106, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; DNA, Complementary; Embryo, Nonmammalian; Endothelium, Vascular; Eye Abnormalities; Humans; Lysophospholipids; Magnesium; Neuropilin-1; Oligonucleotides, Antisense; Sphingomyelin Phosphodiesterase; Sphingosine; Thalidomide; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2; Zebrafish

2005
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2

    Topics: DNA; Down-Regulation; Gene Expression Regulation; Hepatocyte Nuclear Factor 3-alpha; Humans; Lung Neoplasms; Lysophospholipids; Nuclear Proteins; Promoter Regions, Genetic; Protein Kinases; Pulmonary Surfactant-Associated Protein B; RNA, Messenger; Signal Transduction; Sphingosine; Thyroid Nuclear Factor 1; Transcription Factors; Tumor Cells, Cultured

2006
Activation of telomerase and cyclooxygenase-2 in PDGF and FGF inhibition of C2-ceramide-induced apoptosis.
    Journal of cellular physiology, 2009, Volume: 218, Issue:2

    Topics: Animals; Apoptosis; Cell Survival; Ceramides; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Mice; NIH 3T3 Cells; Phosphorylation; Platelet-Derived Growth Factor; Sphingosine; Telomerase

2009
Nerve growth factor, sphingomyelins, and sensitization in sensory neurons.
    Sheng li xue bao : [Acta physiologica Sinica], 2008, Oct-25, Volume: 60, Issue:5

    Topics: Action Potentials; Animals; Cells, Cultured; Ceramides; Lysophospholipids; Nerve Growth Factor; Patch-Clamp Techniques; Phosphotransferases (Alcohol Group Acceptor); Sensory Receptor Cells; Signal Transduction; Sphingomyelins; Sphingosine

2008
Synthesis of sphingosine is essential for oxidative stress-induced apoptosis of photoreceptors.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:2

    Topics: Animals; Apoptosis; Cells, Cultured; Cytochromes c; Docosahexaenoic Acids; Enzyme Inhibitors; In Situ Nick-End Labeling; Lysophospholipids; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Oxidants; Oxidative Stress; Palmitic Acid; Paraquat; Phosphotransferases (Alcohol Group Acceptor); Photoreceptor Cells, Vertebrate; Rats; Rats, Wistar; Reactive Oxygen Species; Sphingosine

2010
Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway.
    The Journal of biological chemistry, 2012, Nov-16, Volume: 287, Issue:47

    Topics: Animals; Autophagy; Ceramides; CHO Cells; Cricetinae; Cricetulus; Gene Knockdown Techniques; HL-60 Cells; Humans; Lysophospholipids; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Lysosphingolipid; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingosine; TOR Serine-Threonine Kinases

2012
Sphingosine-1-phosphate inhibits ceramide-induced apoptosis during murine preimplantation embryonic development.
    Theriogenology, 2013, Volume: 80, Issue:3

    Topics: Animals; Apoptosis; Blastocyst; Caspases; Embryo Culture Techniques; Embryonic Development; Female; Gene Expression Regulation, Developmental; Lysophospholipids; Mice; Pregnancy; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Tumor Suppressor Protein p53

2013