n-acetylsphingosine and okadaic acid

n-acetylsphingosine has been researched along with okadaic acid in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (53.33)18.2507
2000's6 (40.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deli, E; Kiss, Z1
Welsh, N1
Bergstrom, R; Jackson, J; Meisinger, J; Metz, RJ; Patel, S; Vellody, K; Wright, MA; Young, MR1
Birnbaum, MJ; Pittman, RN; Summers, SA; Zhou, H1
Carabillò, M; Di Liberto, D; Giuliano, M; Lauricella, M; Tesoriere, G; Vento, R1
Ammon, HP; Cartus, T; Drews, G; Heurich, RO1
Hatch, GM; Kelly, SL; Xu, FY1
Fahey, AA; Hoffbrand, AV; Lewin, J; Mehta, AB; Mengubas, K; Wickremasinghe, RG1
Cheng, S; Mao, J; Rehder, V1
Lai, MT; Vlahos, CJ; Zinda, MJ1
Balendran, A; Batty, IH; Blair, AS; Downes, CP; Hajduch, E; Hundal, HS; Litherland, GJ1
Aragonés, MD; Catalán, RE; Collado, MP; Fernández, I; Latorre, E1
Ito, M1
Deng, X; Xin, M1
Jun Yoo, S; Jun, EK; Kim, A; Kim, H; Kim, JH; Koh, GY; Moon, JH; Park, G; Soon Baik, C; Taek Lee, H; Yoon, BS; You, S1

Other Studies

15 other study(ies) available for n-acetylsphingosine and okadaic acid

ArticleYear
Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts.
    The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3)

    Topics: 3T3 Cells; Alkaloids; Animals; Bryostatins; Down-Regulation; Drug Interactions; Ethers, Cyclic; Hydrolysis; Lactones; Macrolides; Mice; Okadaic Acid; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Protein Kinase C; Sphingomyelin Phosphodiesterase; Sphingosine; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1992
Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F.
    The Journal of biological chemistry, 1996, Apr-05, Volume: 271, Issue:14

    Topics: Activating Transcription Factor 2; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Ceramides; Cyclic AMP Response Element-Binding Protein; Diglycerides; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Insulin; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Leucine Zippers; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Nitric Oxide Synthase; Okadaic Acid; Oligonucleotides; Proto-Oncogene Proteins c-jun; Rats; Receptors, Interleukin-1; Signal Transduction; Sphingomyelins; Sphingosine; Transcription Factors; Type C Phospholipases

1996
Vitamin D3 and ceramide reduce the invasion of tumor cells through extracellular matrix components by elevating protein phosphatase-2A.
    Invasion & metastasis, 1996, Volume: 16, Issue:6

    Topics: Animals; Blotting, Western; Cholecalciferol; Enzyme Activation; Extracellular Matrix; Humans; Laminin; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2; Sphingosine; Transfection; Vitronectin

1996
Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis.
    The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26

    Topics: Animals; Apoptosis; Cell Membrane Permeability; COS Cells; Enzyme Inhibitors; Motor Neurons; Okadaic Acid; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sphingosine; Tumor Cells, Cultured

1998
Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide.
    Molecular and cellular biochemistry, 1998, Volume: 185, Issue:1-2

    Topics: Apoptosis; Bacterial Proteins; Blotting, Western; Cell Survival; Ceramides; DNA Fragmentation; Humans; Interleukin-1; Nucleosomes; Okadaic Acid; Proteins; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma; Sphingomyelin Phosphodiesterase; Sphingosine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Distribution of protein phosphatases type 1 and 2A in RINm5F cells.
    Regulatory peptides, 1998, Oct-16, Volume: 77, Issue:1-3

    Topics: Animals; Biomarkers; Cell Fractionation; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Enzyme Inhibitors; Heparin; Histone Chaperones; Islets of Langerhans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylase a; Protamines; Proteins; Rats; Sphingosine; Transcription Factors; Tumor Cells, Cultured

1998
N-Acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells.
    The Biochemical journal, 1999, Feb-01, Volume: 337 ( Pt 3)

    Topics: Animals; Cardiolipins; Cell Line; Cell Membrane Permeability; Ceramides; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Enzyme Inhibitors; Ligases; Marine Toxins; Mitochondria, Heart; Myocardium; Nucleotides; Okadaic Acid; Oxazoles; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Rats; Sphingosine; Tumor Necrosis Factor-alpha

1999
Killing of T lymphocytes by synthetic ceramide is by a nonapoptotic mechanism and is abrogated following mitogenic activation.
    Experimental cell research, 1999, May-25, Volume: 249, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Enzyme Activation; Humans; Jurkat Cells; Lymphocyte Activation; Mitogens; Neoplastic Stem Cells; Okadaic Acid; Phytohemagglutinins; Sphingosine; T-Lymphocytes

1999
Filopodial behavior is dependent on the phosphorylation state of neuronal growth cones.
    Cell motility and the cytoskeleton, 2000, Volume: 47, Issue:4

    Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Carrier Proteins; Cells, Cultured; Cerebrosides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Genistein; Growth Cones; Indole Alkaloids; Intracellular Signaling Peptides and Proteins; Models, Biological; Myosin-Light-Chain Kinase; Naphthalenes; Neurons; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pseudopodia; Signal Transduction; Snails; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Vanadates

2000
Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells.
    Biochemical and biophysical research communications, 2001, Feb-02, Volume: 280, Issue:4

    Topics: Androstadienes; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Marine Toxins; Okadaic Acid; Oxazoles; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Serine; Sphingosine; Threonine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Wortmannin

2001
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.
    Diabetologia, 2001, Volume: 44, Issue:2

    Topics: Biological Transport; Cell Line; Cell Membrane; Enzyme Activation; Glucose; Glycogen; Inositol Phosphates; Insulin; Insulin Receptor Substrate Proteins; Muscle, Skeletal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingosine

2001
Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide.
    European journal of biochemistry, 2003, Volume: 270, Issue:1

    Topics: Animals; Brain; Caspase 3; Caspase Inhibitors; Caspases; Ceramides; Endothelin-1; Enzyme Inhibitors; Flavonoids; Hydrolysis; Male; Okadaic Acid; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Phosphoprotein Phosphatases; Plasmalogens; Protein Phosphatase 2; Quinacrine; Rats; Rats, Wistar; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingosine

2003
Insulin or bFGF and C2 ceramide increase newborn rat retinal ganglion cell survival rate.
    Biochemical and biophysical research communications, 2003, Feb-07, Volume: 301, Issue:2

    Topics: Animals; Animals, Newborn; Carbazoles; Cell Separation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Indole Alkaloids; Insulin; Okadaic Acid; Rats; Retinal Ganglion Cells; Signal Transduction; Sphingosine

2003
Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation.
    The Journal of biological chemistry, 2006, Jul-07, Volume: 281, Issue:27

    Topics: Antigens, Polyomavirus Transforming; Apoptosis; bcl-2-Associated X Protein; Catalytic Domain; Cell Line, Tumor; Enzyme Inhibitors; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Protein Conformation; Protein Phosphatase 2; Sphingosine; Structure-Activity Relationship

2006
Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal.
    Stem cells (Dayton, Ohio), 2010, Volume: 28, Issue:5

    Topics: Biomarkers; Cell Differentiation; Cell Division; Cell Line; Culture Media, Conditioned; Down-Regulation; Embryonic Stem Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Okadaic Acid; Pluripotent Stem Cells; Protein Phosphatase 2; Signal Transduction; Sphingosine

2010