n-acetylserotonin has been researched along with melatonin in 247 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (31.58) | 18.7374 |
| 1990's | 66 (26.72) | 18.2507 |
| 2000's | 40 (16.19) | 29.6817 |
| 2010's | 44 (17.81) | 24.3611 |
| 2020's | 19 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Clemens, JA; Crowell, TA; Flaugh, ME; Sawyer, BD | 1 |
| Benatalah, Z; Brémont, B; Dangy-Caye, AL; Delagrange, P; Gaudy, F; Langlois, M; Mathé-Allainmat, M; Renard, P; Shen, S; Sicsic, S | 1 |
| Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Boutin, JA; Calamini, B; Mesecar, AD; Santarsiero, BD | 1 |
| Boersma, YL; Dekker, FJ; Dömling, ASS; Eleftheriadis, N; Wójcik, M; Zwinderman, MRH | 1 |
| Andrade, RB; Bougie, D; Boxer, MB; Brimacombe, KR; Brown, LE; Brown, MK; Burns, NZ; Cha, JK; Cheff, DM; Cheng, K; Clardy, J; Clement, JA; Coussens, NP; Crooks, PA; Cuny, GD; Dillon, C; Dorjsuren, D; Eastman, RT; Ganor, J; Garg, NK; Goess, BC; Grossman, RB; Guha, R; Hall, MD; Henderson, MJ; Huang, R; Hughes, CC; Iannotti, MJ; Inglese, J; Itkin, Z; Jadhav, A; Johnston, JN; Joullie, MM; Karavadhi, S; Kearney, SE; Kinghorn, AD; Kingston, DGI; Klumpp-Thomas, C; Krische, MJ; Kwon, O; Lee, TD; Lynch, C; Maimone, TJ; Majumdar, S; Maloney, KN; Mevers, EE; Michael, S; Mohamed, E; Moreno, J; Morrill, LA; Murphy, BT; Nagorny, P; Olson, DE; Overman, LE; Picazo, E; Porco, JA; Ren, T; Rivas, F; Rohde, JM; Ross, SA; Roth, JS; Sakamuru, S; Sarpong, R; Sharma, I; Shaw, JT; Shen, B; Shen, M; Shi, W; Shinn, P; Simeonov, A; Snyder, JK; Stephenson, CRJ; Sun, W; Susick, RB; Tan, DS; Tang, Y; Taylor, RE; Thomson, RJ; Titus, SA; Verano, AL; Vosburg, DA; Wan, KK; Wu, J; Wuest, WM; Xia, M; Xu, Z; Yasgar, A; Zahoránszky-Kőhalmi, G; Zakarian, A; Zhang, Y; Zhang, YQ; Zhao, J; Zhao, T; Zheng, W; Zuo, Z | 1 |
| Atkinson, BN; Bayle, ED; Fish, PV; Steadman, D; Svensson, F; Vincent, JP; Whiting, P; Willis, NJ; Woodward, HL | 1 |
| Engel, JN; Klein, DC; Martin, JE | 1 |
| Little, JC; Reiter, RJ; Rudeen, PK; Sackman, JW; Waring, PJ | 1 |
| Karbownik, M; Lewiński, A; Wajs, E | 1 |
| Lu, Y; Pang, SF; Yuan, H | 1 |
| Lewiński, A; Sewerynek, E; Szkudliński, M; Wajs, E | 1 |
| Chin, JR | 1 |
| Buzzell, GR; Menendez-Pelaez, A; Reiter, RJ; Rodriguez, C | 1 |
| Anisimov, VN; Bondarenko, LA | 1 |
| Blengio, M; Ferretti, C; Genazzani, E; Ghi, P | 1 |
| Duffy, JD; McIntyre, IM; Oxenkrug, GF; Requintina, PJ | 1 |
| Niles, L | 1 |
| Lewiński, A; Wajs, E | 1 |
| Wainwright, SD | 1 |
| Satoh, T; Shimada, K; Wakabayashi, H | 2 |
| Bylund, DB; Creighton, JA; Paredez, S; Petterborg, LJ; Rudeen, PK | 1 |
| Allen, AE; Nir, I; Pang, SF | 2 |
| Lewiński, A; Pawlikowski, M; Rybicka, I; Szkudliński, M; Wajs, E | 1 |
| Kuchel, GA; Sherman, RL; Zigmond, RE | 1 |
| Flügge, G; Laitinen, JT; Saavedra, JM | 1 |
| Anderson, GF; Blaivas, M; Dragovic, L; Oxenkrug, GF; Riederer, P | 1 |
| Bowman, DC; McNulty, JA; McReynolds, HD | 1 |
| Dragovic, LJ; Marks, BH; Oxenkrug, GF; Yuwiler, A | 1 |
| Daya, S; Welman, AD | 1 |
| Goldman, H; McCauley, R; McIntyre, IM; Murphy, S; Oxenkrug, GF | 1 |
| McIntyre, IM; Oxenkrug, GF | 1 |
| Champney, TH; Craft, CM; Holtorf, AP; Reiter, RJ | 1 |
| McNulty, JA; Prechel, MM; Simmons, WH | 1 |
| Bondarenko, L; Rom-Bugoslavskaja, ES | 1 |
| Brown, GM; Grota, LJ; Psarakis, S | 1 |
| Dakshinamurti, K; Paulose, CS; Siow, YL; Viswanathan, M | 1 |
| Oxenkrug, GF; Reuss, S | 1 |
| Karasek, E; Kunert-Radek, J; Lewiński, A; Pawlikowski, M; Sewerynek, E; Zerek-Mełeń, G | 1 |
| Mitchell, CK; Redburn, DA | 1 |
| Filipowicz, C; McCauley, R; McIntyre, IM; Oxenkrug, GF | 1 |
| Gharib, A; Pacheco, H; Pévet, P; Reynaud, D; Sarda, N; Vivien-Roels, B | 1 |
| Lewiński, A; Sewerynek, E | 2 |
| Forbes, HJ; Morton, DJ | 1 |
| Attanasio, A; Gupta, D; Sato, T; Wake, K | 1 |
| Aizawa, Y; Satoh, T; Shimada, K; Wakabayashi, H | 1 |
| Lewiński, A; Sewerynek, E; Szkudliński, M; Zelazowska, E; Zelazowski, P; Zerek-Mełeń, G | 1 |
| Hill, BT; Shellard, SA; Whelan, RD | 1 |
| Kunert-Radek, J; Lysoń, K; Pawlikowski, M; Stepień, H | 1 |
| Leone, RM; Silman, RE; Young, IM | 1 |
| Callebert, J; Finocchiaro, L; Jallon, JM; Launay, JM | 1 |
| Francis, PL; Leone, AM; McKenzie-Gray, B | 1 |
| Lewiński, A; Sewerynek, E; Szkudliński, M; Zerek-Mełeń, G | 1 |
| Blask, DE; Hill, SM | 1 |
| Oswald, RE; Papke, RL; Podleski, TR | 1 |
| Cairncross, KD; Foley, PB | 1 |
| Francis, PL; Leone, AM; Silman, RE | 1 |
| Brown, GM; Pang, SF; YoungLai, EV | 1 |
| Clifford, J; Pulido, O | 1 |
| Attanasio, A; Gupta, D; Rager, K | 1 |
| Brown, GM; Campbell, L; Grota, LJ; Seggie, J | 1 |
| Pang, SF; Tang, F; Tang, PL | 2 |
| He, ZC; Huang, CY; Ng, MT; Pang, SF | 1 |
| Grady, RK; Klein, DC; Mefford, IN; Namboodiri, MA; Sugden, D | 1 |
| Reiter, RJ | 1 |
| Garrick, NA; Markey, SP; Murphy, DL; Tamarkin, L; Taylor, PA | 1 |
| Bubenik, GA | 1 |
| Francis, P; Leone, RM; Silman, RE; Stovell, P; Young, IM | 1 |
| Yuwiler, A | 1 |
| Brown, GM; Burns, TG; Grota, LJ; Ho, AK | 1 |
| Brown, GM; Chik, CL; Ho, AK; Joshi, MG | 1 |
| Aimoto, T; Chiou, GC; Chiou, LY | 1 |
| Brown, GM; Grota, LJ; Niles, LP; Pulido, O | 1 |
| Frohman, CE; Hryhorczuk, LM; McIntyre, IM; Novak, EA; Oxenkrug, GF | 1 |
| Anderson, GM; Cohen, DJ; Young, JG; Young, SN | 1 |
| Morton, DJ; Potgieter, B | 1 |
| de Paul Lynch, V; Friedman, E; Yocca, FD | 1 |
| Beamish, FW; George, JC; John, TM | 1 |
| Brown, GM; Chambers, JW; Niles, LP; Pang, SF | 1 |
| Cooper, TB; Friedman, E; Yocca, FD | 1 |
| Kaufman, S; Milstien, S | 1 |
| Brown, G; Grota, LJ; Pulido, O | 1 |
| Brown, GM; Niles, LP | 1 |
| Collin, JP; Falcon, J; Geffard, M; Juillard, MT; Seguela, P; Steinbusch, HW | 1 |
| Brown, GM; Chan, MY; Pang, SF; Tang, PL | 1 |
| Chow, PH; Pang, SF; Tso, EC; Wong, TM | 1 |
| Champney, TH; Holtorf, AP; Reiter, RJ; Steger, RW | 1 |
| Leone, RM; Silman, RE | 1 |
| Giulidori, P; Stramentinoli, G | 1 |
| Balemans, MG; Mans, D; Smith, I; Van Benthem, J | 1 |
| Pang, SF; Tang, F | 1 |
| Pang, SF; Tang, PL | 1 |
| Delaage, MA; Geffard, MR; Puizillout, JJ | 1 |
| Brown, GM; Grota, LJ; Pulido, OM | 1 |
| Katoh, S; Sueoka, T; Yamada, S | 1 |
| Chow, PH; Pang, SF; Tang, PL; Yu, HS | 1 |
| Brown, GM; Liu, HW; Pang, SF; Tsui, HW; Yip, MK | 1 |
| Pang, SF; Tang, PL; Yip, MK; Yu, HS | 1 |
| Brown, GM; Pang, SF; Tang, PL; Yu, HS | 1 |
| Balemans, MG; de Reuver, GF; Smith, I | 1 |
| Driscoll, P; Oxenkrug, GF; Requintina, PJ | 1 |
| McIntyre, IM; Oxenkrug, GF; Requintina, PJ; White, K | 1 |
| Chapman, CB; Sitaram, BR; Sitaram, M; Traut, M | 1 |
| Oxenkrug, GF; Requintina, PJ | 4 |
| Oxenkrug, GF; Requintina, PJ; Reuss, S; Riemann, R | 1 |
| Oxenkrug, GF; Requintina, PJ; White, K; Yuwiler, A | 1 |
| Brammer, GL | 1 |
| Behnke, B; Koopmann, K; Krone, W; Müller-Wieland, D | 1 |
| Christon, R; Delton, I; Durand, G; Gazzah, N; Gharib, A; Lagarde, M; Molière, P; Sarda, N | 1 |
| Buchanan, BA; Porter, JK; Stuedemann, JA; Thompson, FN; Tucker, HA | 1 |
| Cairncross, KD; McLeod, SD | 1 |
| Pruski, D; Slominski, A | 1 |
| Andersson, RG; Mårtensson, LG | 1 |
| Akutsu, H; Harumi, T; Matsushima, S | 1 |
| Baker, J; Ermak, G; Gaudet, SJ; Grande, M; Guisti, LW; Rosano, TG; Slominski, A | 1 |
| Castrucci, AM; Filadelfi, AM | 1 |
| Míguez, JM; Pévet, P; Simonneaux, V | 1 |
| Adam, CL; Hannah, LT; Kyle, CE; Williams, LM | 1 |
| Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD | 1 |
| Longoni, B; Marchiafava, P; Pryor, WA | 1 |
| Hattori, A; Itoh, MT; Sumi, Y | 1 |
| Itoh, MT; Nomura, T; Sumi, Y | 1 |
| Brugger, P; Herold, M; Marktl, W | 1 |
| Harumi, T; Matsushima, S | 1 |
| Hayashi, K; Morioka, N; Okatani, Y; Sagara, Y; Watanabe, K | 2 |
| Behl, C; Lezoualc'h, F; Sparapani, M | 1 |
| Garratt, PJ; Pickering, H; Sugden, D; Teh, MT | 1 |
| Barsacchi, R; Carloni, P; Damiani, E; Donato, L; Greci, L; Kusmic, C | 1 |
| Aldegunde, M; Míguez, JM; Recio, J; Sánchez-Barceló, E | 1 |
| Behl, C; Holsboer, F; Post, A | 1 |
| Cole, PA; De Angelis, J; Khalil, EM | 1 |
| Chanut, E; Dkhissi, O; Nguyen-Legros, J; Repérant, J; Trouvin, JH; Versaux-Botteri, C | 1 |
| Afeche, SC; Bartol, I; Canteras, NS; Cipolla-Neto, J; Delagrange, P; Guardiola-Lemaitre, B; Mota, SR; Ribeiro-Barbosa, ER; Skorupa, AL | 1 |
| Calvo, JR; García-Pergañeda, A; Guerrero, JM; Paz Romero, M; Pozo, D; Rafii-El-Idrissi, M | 1 |
| Abuja, PM; Liebmann, PM; Schauenstein, K; Wölfler, A | 1 |
| Amemiya, A; Ishizuka, B; Itoh, MT; Kuribayashi, Y; Sumi, Y | 1 |
| Reiter, RJ; Siu, AW; To, CH | 1 |
| Liburdy, R; Mori, A; Noda, Y; Packer, L | 1 |
| Afanasiev, A; Bachurin, S; Beznosko, B; Lermontova, N; Mukhina, T; Oxenkrug, G; Serkova, T; Shevtzova, E; Vankin, G | 1 |
| Delagrange, P; Kopp, C; Misslin, R; Rettori, M; Vogel, E | 1 |
| Ferreira, ZS; Markus, RP; Mortani Barbosa, EJ | 1 |
| Garcia, JJ; Manchester, LC; Qi, W; Reiter, RJ; Siu, AW; Tan, DX | 1 |
| Calvo, JR; García, JJ; Karbownik, M; Ortiz, GG; Reiter, RJ; Tan, DX | 1 |
| Afeche, SC; Bartol, I; Canteras, NS; Cipolla-Neto, J; Mota, SR; Scialfa, JH; Skorupa, AL; Terra, IM | 1 |
| Arand, M; Friedberg, T; Härtter, S; Hiemke, C; Oesch, F; Wang, X; Weigmann, H | 1 |
| Cole, PA; Ho, AK; Scheibner, KA; Zheng, W | 1 |
| Gitto, E; Karbownik, M; Lewiñski, A; Reiter, RJ | 1 |
| Bachurin, S; Oxenkrug, G; Requintina, P | 1 |
| Dubocovich, ML; Farsky, SH; Lopes, C; Lotufo, CM; Markus, RP | 1 |
| Bondarenko, LA; Gubina-Vakulik, GI | 1 |
| Jing, C; Johansson, O; Kauser, S; McNulty, J; Pisarchik, A; Semak, I; Slominski, A; Slugocki, G; Sweatman, T; Szczesniewski, A; Tobin, DJ; Wortsman, J | 1 |
| Bick, R; Bryant-Thomas, T; Chyan, YJ; Cruz-Sanchez, F; Dubocovich, M; Pappolla, MA; Perry, G; Poeggeler, B; Simovich, MJ; Smith, MA | 1 |
| Burkhardt, S; Dose, A; Hardeland, R; Poeggeler, B; Schoenke, M; Thuermann, S | 1 |
| Castrucci, AM; Souza, AV; Visconti, MA | 1 |
| Kauser, S; Pisarchik, A; Slominski, A; Tobin, DJ; Wortsman, J; Zbytek, B | 1 |
| AXELROD, J; REDFIELD, BG; WEISSBACH, H | 1 |
| AXELROD, J; WEISSBACH, H | 1 |
| Catalá, A; Guajardo, MH; Terrasa, AM | 1 |
| Garcia, CR; Hotta, CT; Markus, RP | 1 |
| Akhisaroglu, M; Arslan, AD; Kurtuncu, M; Manev, H; Uz, T | 1 |
| Ahmed, R; Akhisaroglu, M; Kurtuncu, M; Manev, H; Uz, T | 1 |
| Brocco, MA; Caputto, BL; Carpentieri, AR; Contin, MA; Garbarino-Pico, E; Guido, ME; Panzetta, P; Rosenstein, RE; Sarmiento, MI | 1 |
| Assreuy, J; Avellar, MC; Duma, D; Fernandes, PA; Ferreira, ZS; Markus, RP | 1 |
| Borjigin, J; Liu, T | 2 |
| Jaber, BL; Oxenkrug, GF; Perianayagam, MC | 1 |
| Ayano, E; Kanazawa, H; Kanezawa, M; Kikuchi, A; Morita-Murase, Y; Nagata, Y; Okano, T; Sakamoto, C; Suzuki, Y | 1 |
| Banerjee, S; Chatterji, U; Chaudhuri-Sengupta, S; Maiti, BR; Nag, D; Nag, TC; Saha, I | 1 |
| Catalá, A; Fagali, N | 2 |
| Catalá, A; Leaden, PJ | 1 |
| Behrends, A; Grube, S; Haldar, C; Hardeland, R; Poeggeler, B; Riediger, S | 1 |
| Gesing, A; Karbownik-Lewinska, M | 1 |
| Oxenkrug, GF; Requintina, PJ; Sablin, SO | 1 |
| Afeche, SC; Barbosa, R; Cipolla-Neto, J; Scialfa, JH; Simonneaux, V; Terra, IM | 1 |
| Antonova, M; Korik, E; Semak, I; Slominski, A; Wortsman, J | 1 |
| Catalá, A; Gavazza, M | 1 |
| Dougherty, GG; Kaddurah-Daouk, R; Keshavan, MS; Krishnan, RR; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Rozen, S; Yao, JK | 1 |
| Slominski, AT; Sweatman, TW; Zmijewski, MA | 1 |
| Bieszczad-Bedrejczuk, E; Karowicz-Bilińska, A; Sadowska-Woda, I; Wójcik, N | 1 |
| Chang, Q; Iuvone, PM; Jang, SW; Liu, X; Pradoldej, S; Tosini, G; Ye, K | 1 |
| Back, K; Kang, K; Kim, YS; Lee, K; Park, S | 1 |
| Sewerynek, E; Stuss, M; Wiktorska, JA | 1 |
| Gupta, BB; Singh, KM; Yanthan, L | 1 |
| Amado, D; Cabral, FR; Cavalheiro, EA; Lima, E; Naffah-Mazzacoratti, Mda G | 1 |
| Borjigin, J; Calinescu, AA; Zhang, LS | 1 |
| Calcutt, MW; Carter, MD; Hachey, DL; Malow, BA; Rose, KL | 1 |
| Adamska, I; Kedzierska, U; Majewski, PM; Piesiewicz, A; Skwarlo-Sonta, K; Usarek, M; Zeman, M | 1 |
| Alonso Gómez, AL; Delgado, MJ; Moure, AL; Nisembaum, LG; Tinoco, AB; Valenciano, AI | 1 |
| Coon, SL; Klein, DC; Matsuo, M | 1 |
| Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T | 1 |
| Diss, LB; Fidalgo, S; Patel, BA; Robinson, SD; Wu, Y; Yeoman, MS | 1 |
| Back, K; Byeon, Y; Kim, YS; Lee, HY; Park, S | 1 |
| Hanna, S; Janjetovic, Z; Jarrett, SG; Kim, TK; Nahmias, ZP; Reiter, RJ; Slominski, AT | 1 |
| Anderson, G; Maes, M | 1 |
| Lewczuk, B; Prusik, M; Przybylska-Gornowicz, B; Ziółkowska, N | 2 |
| Back, K; Byeon, Y; Lee, HY; Lee, K | 1 |
| Amsellem, F; Boudebesse, C; Bourgeron, T; Callebert, J; Delorme, R; Drouot, X; Gillberg, C; Goubran-Botros, H; Laouamri, H; Launay, JM; Le Dudal, K; Leboyer, M; Ngo-Nguyen, N; Pagan, C | 1 |
| Jagota, A; Reddy, MY | 1 |
| Anderson, G; Rodriguez, M | 1 |
| Álvarez-Diduk, R; Galano, A; Reiter, RJ; Tan, DX | 1 |
| Choudhury, A; Ganguly, S; Palit, G; Shukla, S; Singh, S | 1 |
| Baallal Jacobsen, SA; Borodina, I; Chen, X; Forster, J; Germann, SM; Harrison, SJ; Jensen, NB; Luo, H; Maury, J; Schneider, K; Stahlhut, SG; Zhu, J | 1 |
| Dickson, EJ; Hille, B; Jung, SR; Koh, DS; Yu, H | 1 |
| Dargenio-Garcia, L; Fernandes, PA; Ferreira, ZS; Markus, RP; Petrilli-Lapa, CL; Souza, Eda S; Souza-Teodoro, LH | 1 |
| Buxaderas, S; Castellari, M; López-Tamames, E; Ribas-Agustí, A; Riu-Aumatell, M; Tudela, R | 1 |
| Ariyannur, PS; Kirmani, BF; Moffett, JR; Namboodiri, AM; Ribeiro, R; Tanaka, M; Wen, J; Zhang, Y | 1 |
| Frühauf, P; Gerner, C; Wolrab, D | 1 |
| Alkozi, HA; Perez de Lara, MJ; Pintor, J; Sánchez-Naves, J | 1 |
| Back, K; Lee, HY; Lee, K | 1 |
| Benabou, M; Bourgeron, T; Callebert, J; Delorme, R; Huguet, G; Leblond, CS; Leboyer, M; Maronde, E; Millot, GA; Pagan, C; Rolland, T | 1 |
| Han, L; He, C; Luo, H | 1 |
| Chakraborty, SB; Chatterjee, A; Chatterji, U; Maiti, BR; Pradhan, D; Saha, I | 1 |
| Dąbrowski, M; Hanuszewska, M; Lewczuk, B; Martniuk, K; Prusik, M; Zielonka, Ł; Ziółkowska, N | 1 |
| Aly, H; Bhattacharya, P; Chiocca, EA; Cui, Y; Fu, J; Jiang, J; Johnson, MD; Lawler, SE; Liu, Y; Luo, C; Ma, H; Reiter, RJ; Rozental, R; Wang, X; Yang, H; Yang, Q; Yao, J; Zhang, X; Zhou, S | 1 |
| Coon, SL; Holtzclaw, L; Kelley, MW; Kelly, MC; Klein, DC; Mays, JC; Rath, MF | 1 |
| Su, S; Wang, S; Wang, W; Ye, L; Yu, H | 1 |
| Anderson, G | 3 |
| Bussi, IL; de la Iglesia, HO; Hague, C; Hille, B; Koh, DS; Lee, BH | 1 |
| Janjetovic, Z; Kim, TK; Kleszczyński, K; Li, W; Lin, Z; Postlethwaite, A; Reiter, RJ; Semak, I; Skobowiat, C; Slominski, AT; Steketee, JD; Sweatman, T; Tobin, DJ | 1 |
| Číž, M; Lojek, A; Vašíček, O | 1 |
| Beltran, G; Carrasco-Galán, F; Cerezo-López, AB; Fernández-Cruz, E; García-Parrilla, MC; Morcillo-Parra, MÁ; Torija, MJ; Troncoso, AM; Valero, E | 1 |
| Babyak, MA; Boyle, SH; Georgiades, A; Grichnik, K; Kaddurah-Daouk, R; Kuhn, CM; Matson, SA; Matson, WR; Mirjankar, N; Reavis, ZW; Sarangi, S; Siegler, IC; Stafford-Smith, M; Suarez, EC; Williams, RB | 1 |
| Chen, S; Feng, X; Li, Z; Mou, Z; Reiter, RJ; Yao, Z; Zhang, J; Zhang, R; Zhang, X; Zhao, D | 1 |
| Back, K; Choi, GH; Lee, K | 1 |
| Hanuszewska-Dominiak, M; Lewczuk, B; Martyniuk, K | 2 |
| Gong, X; Hu, L; Li, Y; Liu, Y; Ma, F; Yang, S; Yue, H; Zhang, J; Zhou, K | 1 |
| Ferreira, ZS; Markus, RP; Muxel, SM; Quiles, CL; Sousa, KS; Trevisan, IL | 1 |
| Klein, DC | 1 |
| Heo, G; Im, E; Jeong, S; Ju, S; Jung, Y; Kang, C; Kim, J; Lee, J; Park, S; Yoo, JW; Yoon, IS | 1 |
| Guo, XD; Kang, JH; Kang, XW; Wang, YD | 1 |
| Borjigin, J; Fukami, T; Huang, Z; Konishi, K; Li, Y; Sakai, Y; Tashiro, K | 1 |
| Guido, ME; Marchese, NA; Rios, MN | 1 |
12 review(s) available for n-acetylserotonin and melatonin
| Article | Year |
|---|---|
[Factors stimulating and/or inhibiting the growth processes in the adrenal cortex. II. The role of the renin-angiotensin system, tissue growth factors, pineal indole amines and the nervous system].
Topics: Adrenal Cortex; Adrenergic Fibers; Atrial Natriuretic Factor; Growth Inhibitors; Growth Substances; Humans; In Vitro Techniques; Melatonin; Prostaglandins; Renin-Angiotensin System; Serotonin; Somatostatin | 1991 |
Interrelationships of DNA cycles and melatonin synthesis.
Topics: Animals; Arylamine N-Acetyltransferase; Biological Clocks; Cells, Cultured; Chickens; Choline; Circadian Rhythm; DNA Replication; Fibroblasts; Melatonin; Norepinephrine; Pineal Gland; Rats; Serotonin; Tryptophan; Uridine | 1991 |
Action spectra, dose-response relationships, and temporal aspects of light's effects on the pineal gland.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Darkness; Dose-Response Relationship, Radiation; Hibernation; Light; Mammals; Melatonin; Pigment Epithelium of Eye; Pineal Gland; Serotonin; Spectrum Analysis; Suprachiasmatic Nucleus; Time Factors | 1985 |
N-Acetylserotonin in the central nervous system.
Topics: Acetyltransferases; Animals; Brain; Chickens; Epitopes; Fluorescent Antibody Technique; Immune Sera; Immunoenzyme Techniques; Indoles; Melatonin; Pineal Gland; Rats; Retina; Serotonin; Tryptophan Hydroxylase | 1984 |
Circadian regulation of pineal gland rhythmicity.
Topics: Animals; Circadian Clocks; CLOCK Proteins; Cryptochromes; Gene Expression Regulation; Humans; Melatonin; Photoperiod; Pineal Gland; Serotonin | 2012 |
Local melatonin regulates inflammation resolution: a common factor in neurodegenerative, psychiatric and systemic inflammatory disorders.
Topics: Humans; Inflammation; Melatonin; Mental Disorders; Neurodegenerative Diseases; Serotonin | 2014 |
Multiple sclerosis: the role of melatonin and N-acetylserotonin.
Topics: Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunologic Factors; Immunosuppressive Agents; Interferon-beta; Lithium Compounds; Melatonin; Multiple Sclerosis; Nootropic Agents; Serotonin; Valproic Acid | 2015 |
The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health.
Topics: Animals; Brain Injuries; Humans; Liver Diseases; Melatonin; Neuroprotective Agents; Osteoporosis; Oxidative Stress; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Regeneration; Serotonin; Sleep | 2019 |
Breast cancer: Occluded role of mitochondria N-acetylserotonin/melatonin ratio in co-ordinating pathophysiology.
Topics: Animals; Breast Neoplasms; Female; Humans; Melatonin; Mitochondria; Oxidative Stress; Serotonin | 2019 |
Integrating Pathophysiology in Migraine: Role of the Gut Microbiome and Melatonin.
Topics: Astrocytes; Dysbiosis; Gastrointestinal Microbiome; Humans; Melatonin; Migraine Disorders; Mitochondria; Neuroglia; Serotonin | 2019 |
Tumor Microenvironment and Metabolism: Role of the Mitochondrial Melatonergic Pathway in Determining Intercellular Interactions in a New Dynamic Homeostasis.
Topics: Brain-Derived Neurotrophic Factor; Homeostasis; Humans; Melatonin; Mitochondria; Neoplasms; Reactive Oxygen Species; Tumor Microenvironment | 2022 |
Neuroprotective Effects of N-acetylserotonin and Its Derivative.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Humans; Melatonin; Neuroprotection; Neuroprotective Agents; Serotonin | 2023 |
235 other study(ies) available for n-acetylserotonin and melatonin
| Article | Year |
|---|---|
Synthesis and evaluation of the antiovulatory activity of a variety of melatonin analogues.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Melatonin; Ovulation; Rats; Serotonin; Structure-Activity Relationship | 1979 |
Synthesis of 2-amido-2,3-dihydro-1H-phenalene derivatives as new conformationally restricted ligands for melatonin receptors.
Topics: Amides; Animals; Ligands; Magnetic Resonance Spectroscopy; Melanocytes; Melanophores; Melatonin; Molecular Conformation; Molecular Structure; Polycyclic Compounds; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Xenopus laevis | 1996 |
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi | 1998 |
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Topics: Binding Sites; Crystallography, X-Ray; Humans; Kinetics; Melatonin; Models, Molecular; Molecular Structure; Protein Binding; Quinone Reductases; Thermodynamics | 2008 |
Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Topics: | 2018 |
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.
Topics: Binding Sites; Catalytic Domain; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Esterases; Humans; Molecular Dynamics Simulation; Small Molecule Libraries; Wnt Signaling Pathway | 2021 |
Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin, and 5-methoxytryptamine.
Topics: 5-Methoxytryptamine; Age Factors; Animals; Gonadotropin-Releasing Hormone; In Vitro Techniques; Indoles; Luteinizing Hormone; Melatonin; Pituitary Gland; Rats; Rats, Inbred Strains; Secretory Rate; Serotonin | 1977 |
The effects of pineal indoles given late in the light period on reproductive organs and pituitary prolactin levels in male golden hamsters.
Topics: Animals; Body Weight; Cricetinae; Genitalia, Male; Indoles; Light; Male; Melatonin; Mesocricetus; Organ Size; Periodicity; Pineal Gland; Pituitary Gland; Prolactin; Serotonin; Testis | 1977 |
Effects of pineal-derived indolic compounds and of certain neuropeptides on the growth processes in the thyroid gland.
Topics: Animals; DNA; Indoles; Male; Melatonin; Mitosis; Neuropeptides; Pineal Gland; Rats; Rats, Wistar; Serotonin; Thymidine; Thyroid Gland; Thyrotropin; Vasoactive Intestinal Peptide | 1992 |
Binding characteristics and regional distribution of [125I]iodomelatonin binding sites in the brain of the human fetus.
Topics: Binding, Competitive; Brain; Brain Chemistry; Fetus; Humans; Hypothalamus; Indoles; Melatonin; Neurotransmitter Agents; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin | 1991 |
Determination of six indolic compounds, including melatonin, in rat pineal using high-performance liquid chromatography with serial fluorimetric-electrochemical detection.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Spectrometry, Fluorescence; Tryptophan | 1990 |
Indole and porphyrin content of the Syrian hamster harderian glands during the proestrous and estrous phases of the estrous cycle.
Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Cricetinae; Estrus; Female; Harderian Gland; Hydroxyindoleacetic Acid; Indoles; Melatonin; Mesocricetus; Porphyrins; Serotonin | 1991 |
[Effects of an epiphyseal peptide preparation epithalamin on serotonin metabolism in the pineal gland of rats].
Topics: 5-Methoxytryptamine; Animals; Cattle; Hydroxyindoleacetic Acid; Male; Melatonin; Peptides; Pineal Gland; Rats; Serotonin; Time Factors | 1990 |
Differential effects of indolepyruvic acid and 5-hydroxytryptophan on indole metabolism in the pineal gland of the rat during the light-dark cycle.
Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Electrochemistry; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1990 |
The response of the pineal melatonin biosynthesis to the selective MAO-A inhibitor, clorgyline, in young and middle-aged rats.
Topics: Aging; Animals; Clorgyline; Hydroxyindoleacetic Acid; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Melatonin interaction with the benzodiazepine-GABA receptor complex in the CNS.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Melatonin; Muscimol; Prosencephalon; Rats; Receptors, GABA-A; Serotonin; Synaptosomes | 1991 |
Effects of melatonin on [3H]-thymidine incorporation into DNA of rat thyroid lobes in vitro.
Topics: Animals; DNA Replication; Dose-Response Relationship, Drug; Drug Interactions; Kinetics; Male; Melatonin; Organ Culture Techniques; Rats; Rats, Inbred Strains; Serotonin; Thymidine; Thyroid Gland; Thyrotropin; Tritium | 1991 |
Effects of diazepam administration on melatonin synthesis in the rat pineal gland in vivo.
Topics: Acetylserotonin O-Methyltransferase; Brain; Catecholamines; Diazepam; Melatonin; Pineal Gland; Serotonin | 1991 |
Effects of adrenergic blockers or bicuculline on diazepam induced changes in rat pineal melatonin synthesis in vivo and in vitro.
Topics: Acetylserotonin O-Methyltransferase; Animals; Bicuculline; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Male; Melatonin; Phenoxybenzamine; Pineal Gland; Propranolol; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Effects of light and an alpha-2-adrenergic agonist on serotonin N-acetyltransferase activity in chick pineal gland.
Topics: Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Brimonidine Tartrate; Chickens; Circadian Rhythm; Melatonin; Photic Stimulation; Pineal Gland; Quinoxalines; Receptors, Adrenergic, alpha; Serotonin; Signal Transduction | 1990 |
The effect of environmental photoperiodicity on indole rhythms and locomotor activity in sighted and eye covered chickens.
Topics: Adaptation, Physiological; Animals; Chickens; Circadian Rhythm; Melatonin; Motor Activity; Photic Stimulation; Pineal Gland; Retina; Sensory Deprivation; Serotonin | 1991 |
Influence of pineal indoleamines on the mitotic activity of gastric and colonic mucosa epithelial cells in the rat: interaction with omeprazole.
Topics: Analysis of Variance; Animals; Colon; Gastric Mucosa; Intestinal Mucosa; Male; Melatonin; Mitosis; Omeprazole; Polyethylene Glycols; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Recovery of function following unilateral denervation, but not unilateral decentralization, of the pineal gland as indicated by measurements of pineal melatonin content and urinary melatonin metabolites.
Topics: Animals; Arylamine N-Acetyltransferase; Central Nervous System; Circadian Rhythm; Denervation; Electrophysiology; Male; Melatonin; Nerve Endings; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Sympathectomy, Chemical | 1990 |
Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Calcium Chloride; Cations, Divalent; Cerebral Ventricles; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium Chloride; Male; Melatonin; Rats; Rats, Inbred Strains; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin; Thionucleotides | 1990 |
Circadian rhythms of human pineal melatonin, related indoles, and beta adrenoreceptors: post-mortem evaluation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Child; Child, Preschool; Circadian Rhythm; Female; Humans; Indoles; Infant; Male; Melatonin; Middle Aged; Pineal Gland; Postmortem Changes; Receptors, Adrenergic, beta; Serotonin; Time Factors | 1990 |
Pineal gland free amino acids and indoles during postnatal development of the rat: correlations in individual glands.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; Glutamates; Indoles; Melatonin; Pineal Gland; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Taurine | 1990 |
Effect of cocaine on rat pineal melatonin synthesis in vivo and in vitro.
Topics: Animals; Arousal; Arylamine N-Acetyltransferase; Circadian Rhythm; Cocaine; Culture Techniques; Dose-Response Relationship, Drug; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Pineal gland as a model to elucidate the primary mode of action of alpha-methyldopa: alpha-methyldopa induces an increase in the synthesis of N-acetylserotonin and melatonin levels by the rat pineal gland.
Topics: Animals; Isoproterenol; Male; Melatonin; Methyldopa; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Effect of superior cervical ganglionectomy on melatonin stimulation by specific MAO-A inhibition.
Topics: Animals; Clorgyline; Ganglia, Sympathetic; Hydroxyindoleacetic Acid; Male; Melatonin; Monoamine Oxidase Inhibitors; Pineal Gland; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1985 |
Stress-induced synthesis of melatonin: possible involvement of the endogenous monoamine oxidase inhibitor (tribulin).
Topics: Animals; Cold Temperature; Hydroxyindoleacetic Acid; Hydroxytryptophol; Isatin; Lorazepam; Male; Melatonin; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin; Stress, Physiological; Tryptophan | 1985 |
Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Cricetinae; Diabetes Mellitus, Experimental; Hydroxyindoleacetic Acid; Insulin; Kinetics; Male; Melatonin; Mesocricetus; Pineal Gland; Rats; Serotonin; Species Specificity; Tryptophan | 1986 |
Correlations of serotonin and its metabolites in individual rat pineal glands over light:dark cycles and after acute light exposure.
Topics: Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Hydroxyindoleacetic Acid; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Seasonal peculiarities of thyroxine influence on the way of serotonin metabolism in the pineal gland of the rat.
Topics: 5-Methoxytryptamine; Animals; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Seasons; Serotonin; Thyroxine | 1987 |
Analgesia induced by N-acetylserotonin in the central nervous system.
Topics: Analgesia; Animals; Cerebral Ventricles; Immune Sera; Injections, Intraperitoneal; Injections, Intraventricular; Male; Melatonin; Morphine; Naloxone; Pain Measurement; Palliative Care; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Pineal indoleamine metabolism in pyridoxine-deficient rats.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Circadian Rhythm; Hydroxyindoleacetic Acid; Isoproterenol; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Vitamin B 6 Deficiency | 1988 |
Chemical sympathectomy and clorgyline-induced stimulation of rat pineal melatonin synthesis.
Topics: 5-Hydroxytryptophan; Animals; Clorgyline; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Sympathectomy, Chemical | 1989 |
Influence of melatonin and N-acetylserotonin on the cyclic AMP concentration in the rat thyroid lobes incubated in vitro.
Topics: Animals; Cyclic AMP; Male; Melatonin; Organ Culture Techniques; Rats; Rats, Inbred Strains; Serotonin; Thyroid Gland; Thyrotropin | 1989 |
Darkness stimulates rapid synthesis and release of melatonin in rat retina.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dark Adaptation; Diffusion; Glutamates; Glutamic Acid; Light; Melatonin; Rats; Rats, Inbred Strains; Retina; Serotonin; Tryptophan | 1989 |
Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatonin.
Topics: Animals; Clorgyline; Hydroxyindoleacetic Acid; Isoenzymes; Male; Melatonin; Phenethylamines; Pineal Gland; Propylamines; Rats; Rats, Inbred Strains; Selegiline; Serotonin | 1985 |
Adenosine analogs elevate N-acetylserotonin and melatonin in rat pineal gland.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Circadian Rhythm; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Melatonin inhibits mitotic activity of adrenocortical cells in vivo and in organ culture.
Topics: Adrenal Cortex; Animals; Cosyntropin; Female; Male; Melatonin; Mice; Mitosis; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Pineal gland hydroxyindole-O-methyl transferase (HIOMT) from rainbow trout (Salmo gairdneri) subject to temperature-dependent substrate inhibition by N-acetylserotonin.
Topics: Acetylserotonin O-Methyltransferase; Animals; Kinetics; Male; Melatonin; Methyltransferases; Pineal Gland; Serotonin; Substrate Specificity; Temperature; Trout | 1989 |
Rhythm development in pineal and circulating serotonin, N-acetylserotonin, and melatonin in Syrian hamsters.
Topics: Animals; Circadian Rhythm; Cricetinae; Darkness; Female; Light; Male; Melatonin; Mesocricetus; Pineal Gland; Radioimmunoassay; Serotonin | 1989 |
Effect of psychotropic drugs on the contents of melatonin, serotonin and N-acetylserotonin in rat pineal gland.
Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Male; Melatonin; Phenytoin; Pineal Gland; Psychotropic Drugs; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Melatonin-induced suppression of human lymphocyte natural killer activity in vitro.
Topics: Cells, Cultured; Humans; Killer Cells, Natural; Melatonin; Osmolar Concentration; Serotonin | 1989 |
Growth inhibitory and cytotoxic effects of melatonin and its metabolites on human tumour cell lines in vitro.
Topics: 5-Methoxytryptamine; 5,6-Dihydroxytryptamine; Cell Line; Drug Screening Assays, Antitumor; Humans; Melatonin; Serotonin; Tryptamines; Tumor Cells, Cultured | 1989 |
Effect of benzodiazepines on the proliferation of mouse spleen lymphocytes in vitro.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; DNA Replication; Lymphocyte Activation; Lymphocytes; Male; Melatonin; Mice; Mice, Inbred BALB C; Reference Values; Serotonin | 1988 |
The mass spectrometric analysis of the urinary metabolites of melatonin and its deuterated analogues, confirming their identity as N-acetylserotonin and 6-hydroxymelatonin.
Topics: Animals; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Melatonin; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Melatonin biosynthesis in Drosophila: its nature and its effects.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, Thin Layer; Drosophila; Drosophila melanogaster; Female; Indoles; Male; Mass Spectrometry; Melatonin; Oviposition; Radioimmunoassay; Serotonin; Sexual Behavior, Animal | 1988 |
Rapid and simple synthesis for the sulphate esters of 6-hydroxy-melatonin and N-acetyl-serotonin.
Topics: Melatonin; Serotonin; Sulfates | 1988 |
The effect of melatonin and N-acetylserotonin on mitotic activity of thyroid gland and adrenal cortex in the rat.
Topics: Adrenal Cortex; Animals; Depression, Chemical; Male; Melatonin; Mitosis; Rats; Rats, Inbred Strains; Serotonin; Thyroid Gland | 1988 |
Effects of melatonin on cancer: studies on MCF-7 human breast cancer cells in culture.
Topics: 5-Methoxytryptamine; Breast Neoplasms; Cell Division; Cell Line; Estradiol; Female; Humans; Kinetics; Melatonin; Prolactin; Serotonin | 1986 |
Effects of pineal factors on the action potentials of sympathetic neurons.
Topics: Action Potentials; Animals; Cells, Cultured; Cytological Techniques; Melatonin; Neurons; Pineal Gland; Rats; Serotonin; Sympathetic Nervous System; Time Factors | 1986 |
Investigation of circadian rhythms for pineal 5-hydroxytryptophol and other indoles in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Hydroxytryptophol; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1987 |
The isolation, purification, and characterisation of the principal urinary metabolites of melatonin.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Melatonin; Serotonin; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfates | 1987 |
Pineal, retinal, serum melatonin, and N-acetylserotonin rhythms in chicks on reversing light regimen and eye covering.
Topics: Animals; Chickens; Circadian Rhythm; Eye; Light; Melatonin; Periodicity; Pineal Gland; Retina; Serotonin | 1987 |
Effects of different photoperiods on circulating levels of melatonin and N-acetylserotonin in the female rabbit.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Female; Melatonin; Pineal Gland; Rabbits; Serotonin | 1986 |
Age-associated changes in the circadian rhythm of retinal N-acetylserotonin and melatonin in rats with pigmented eyes.
Topics: Aging; Animals; Circadian Rhythm; Eye Color; Male; Melatonin; Rats; Retina; Serotonin | 1986 |
Ontogeny of circadian rhythmicity for melatonin, serotonin, and N-acetylserotonin in humans.
Topics: Age Factors; Circadian Rhythm; Female; Humans; Infant; Infant, Newborn; Male; Melatonin; Serotonin | 1986 |
Melatonin inhibits the basal and TSH-stimulated mitotic activity of thyroid follicular cells in vivo and in organ culture.
Topics: Animals; Depression, Chemical; Female; Male; Melatonin; Mice; Mitosis; Organ Culture Techniques; Pineal Gland; Serotonin; Thyroid Gland; Thyrotropin | 1986 |
Melatonin and N-acetylserotonin stress responses: effects of type of stimulation and housing conditions.
Topics: Animals; Cold Temperature; Environment; Ether; Male; Melatonin; Noise; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin; Stress, Physiological | 1985 |
Alloxan-induced diabetes and the pineal gland: differential effects on the levels of pineal N-acetylserotonin, pineal melatonin, and serum melatonin.
Topics: Acetylserotonin O-Methyltransferase; Alloxan; Animals; Diabetes Mellitus, Experimental; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin | 1985 |
[Plasma concentrations of melatonin and N-acetylserotonin in different age groups of human males].
Topics: Adult; Age Factors; Aged; Child; Circadian Rhythm; Humans; Male; Melatonin; Radioimmunoassay; Serotonin | 1985 |
Ovine pineal indoles: effects of L-tryptophan or L-5-hydroxytryptophan administration.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Male; Melatonin; Pineal Gland; Serotonin; Sheep; Time Factors; Tryptophan | 1985 |
Diurnal rhythms of N-acetylserotonin and serotonin in cerebrospinal fluid of monkeys.
Topics: Animals; Circadian Rhythm; Haplorhini; Melatonin; Pineal Gland; Serotonin | 1985 |
The effect of serotonin, N-acetylserotonin, and melatonin on spontaneous contractions of isolated rat intestine.
Topics: Animals; Epinephrine; Female; Ileum; In Vitro Techniques; Kinetics; Melatonin; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man.
Topics: Adult; Biotransformation; Deuterium; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Male; Melatonin; Serotonin; Sulfates | 1985 |
Neonatal steroid treatment reduces catecholamine-induced increases in pineal serotonin N-acetyltransferase activity.
Topics: Acetyltransferases; Aging; Animals; Animals, Newborn; Arylamine N-Acetyltransferase; Catecholamines; DNA; Glucocorticoids; Hydrocortisone; Isoproterenol; Melatonin; Norepinephrine; Organ Culture Techniques; Pineal Gland; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Scheduled feeding and 24-hour rhythms of N-acetylserotonin and melatonin in rats.
Topics: Animals; Circadian Rhythm; Corticosterone; Food; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1985 |
Differential effects of isoproterenol injections on the levels of pineal N-acetyltransferase, serum N-acetylserotonin and melatonin.
Topics: Acetyltransferases; Animals; Injections, Subcutaneous; Isoproterenol; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Melatonergic involvement in diurnal changes of intraocular pressure in rabbit eyes.
Topics: Acetyltransferases; Animals; Choline O-Acetyltransferase; Eye; Intraocular Pressure; Melatonin; Rabbits; Serotonin | 1985 |
Differential effect of carbidopa on the concentration of rat pineal and hypothalamic indoleamines.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Hydroxyindoleacetic Acid; Hypothalamus; Male; Melatonin; Organ Specificity; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Determination of indoles in human and rat pineal.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Hydroxyindoleacetic Acid; Hydroxytryptophol; Indoles; Melatonin; Pineal Gland; Rats; Serotonin; Species Specificity; Spectrometry, Fluorescence; Tryptophan | 1982 |
Relationships between methoxyindoles and hydroxyindoles formed from 5-hydroxytryptamine in rat pineal gland.
Topics: Animals; Female; Hydroxyindoleacetic Acid; Hydroxytryptophol; Indoles; Male; Melatonin; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Effect of chronic lithium treatment on rat pineal rhythms: N-acetyltransferase, N-acetylserotonin and melatonin.
Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Body Weight; Circadian Rhythm; Cyclic AMP; Hydroxyindoleacetic Acid; Isoproterenol; Lithium; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1983 |
Diurnal impact of locomotory activity and melatonin and N-acetylserotonin treatment on blood metabolite levels in the rainbow trout.
Topics: Animals; Blood Glucose; Circadian Rhythm; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Hematocrit; Melatonin; Physical Exertion; Salmonidae; Serotonin; Trout | 1983 |
Effects of P-chlorophenylalanine on pineal and endocrine function in the rat.
Topics: Adrenal Glands; Animals; Blindness; Brain Chemistry; Corticosterone; Endocrine Glands; Fenclonine; Growth Hormone; Male; Melatonin; Norepinephrine; Organ Size; Pineal Gland; Prolactin; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Antidepressant drugs with varying pharmacological profiles alter rat pineal beta adrenergic-mediated function.
Topics: Acetyltransferases; Animals; Antidepressive Agents; Dihydroalprenolol; Imipramine; Iprindole; Male; Melatonin; Phenothiazines; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin; Suprachiasmatic Nucleus | 1984 |
Tetrahydro-sepiapterin is an intermediate in tetrahydrobiopterin biosynthesis.
Topics: Adrenal Medulla; Alcohol Oxidoreductases; Animals; Biopterins; Cattle; Escherichia coli; GTP Cyclohydrolase; Leuconostoc; Melatonin; Pteridines; Pterins; Serotonin; Tetrahydrofolate Dehydrogenase | 1983 |
An immunohistochemical method for the localization of N-acetylserotonin (NAS) in the central nervous system. Description, validation, and application of the technique.
Topics: Animals; Antibody Specificity; Brain Chemistry; Brain Stem; Cerebellar Cortex; Cerebellum; Fluorescent Antibody Technique; Histocytochemistry; Male; Melatonin; Rats; Rats, Inbred Strains; Serotonin | 1983 |
Arginine vasotocin stimulates glucocorticoid secretion in male rats.
Topics: Adenylyl Cyclases; Animals; Corticosterone; Gonadotropin-Releasing Hormone; Male; Melatonin; Prolactin; Rats; Rats, Inbred Strains; Serotonin; Testosterone; Vasotocin | 1983 |
Immunocytochemical localization and circadian variations of serotonin and N-acetylserotonin in photoreceptor cells. Light and electron microscopic study in the teleost pineal organ.
Topics: Animals; Circadian Rhythm; Cross Reactions; Female; Fishes; Histocytochemistry; Immunologic Techniques; Male; Melatonin; Microscopy, Electron; Nialamide; Photoreceptor Cells; Pineal Gland; Seasons; Serotonin | 1984 |
Negative correlation of age and the levels of pineal melatonin, pineal N-acetylserotonin, and serum melatonin in male rats.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Circadian Rhythm; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin; Sexual Maturation | 1984 |
Studies on the kinetics of melatonin and N-acetylserotonin in the rat at mid-light and mid-dark.
Topics: Animals; Circadian Rhythm; Darkness; Injections, Intravenous; Kinetics; Light; Male; Melatonin; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Diurnal variations of melatonin and N-acetylserotonin in the tissues of quails (Coturnix sp.), pigeons (Columba livia), and chickens (Gallus domesticus).
Topics: Animals; Brain; Chickens; Circadian Rhythm; Columbidae; Coturnix; Melatonin; Pineal Gland; Retina; Serotonin | 1983 |
Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland.
Topics: Acetyltransferases; Animals; Male; Melatonin; Periodicity; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Melatonin can be differentially metabolized in the rat to produce N-acetylserotonin in addition to 6-hydroxy-melatonin.
Topics: Animals; Chromatography, Thin Layer; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Melatonin; Rats; Rats, Inbred Strains; Serotonin | 1984 |
A radioenzymatic method for S-adenosyl-L-methionine determination in biological fluids.
Topics: Acetylserotonin O-Methyltransferase; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dogs; Humans; Melatonin; Methyltransferases; Rabbits; Radiochemistry; Rats; S-Adenosylmethionine; Serotonin; Tritium | 1984 |
The influence of GABA on the synthesis of N-acetylserotonin, melatonin, O-acetyl-5-hydroxytryptophol and O-acetyl-5-methoxytryptophol in the pineal gland of the male Wistar rat.
Topics: Acetylation; Animals; Circadian Rhythm; gamma-Aminobutyric Acid; Hydroxytryptophol; In Vitro Techniques; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1983 |
Effect of N-acetylserotonin on the serum level of thyroid-stimulating hormone in the male rat.
Topics: Animals; Male; Melatonin; Rats; Rats, Inbred Strains; Serotonin; Thyrotropin | 1983 |
Decreased serum and pineal concentrations of melatonin and N-acetylserotonin in aged male hamsters.
Topics: Aging; Animals; Cricetinae; Male; Melatonin; Mesocricetus; Pineal Gland; Radioimmunoassay; Serotonin | 1983 |
A single radioimmunological assay for serotonin, N-acetylserotonin, 5-methoxytryptamine, and melatonin.
Topics: 5-Methoxytryptamine; Animals; Antibody Specificity; Chemical Phenomena; Chemistry; Circadian Rhythm; Male; Melatonin; Pineal Gland; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin; Tryptamines | 1982 |
Localization of N-acetylserotonin (NAS) in the rat hindbrain by immunohistology.
Topics: Animals; Brain Chemistry; Fluorescent Antibody Technique; Male; Melatonin; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin | 1981 |
Direct inhibition of brain sepiapterin reductase by a catecholamine and an indoleamine.
Topics: Alcohol Oxidoreductases; Animals; Brain; Catecholamines; Erythrocytes; Indoles; Kinetics; Male; Melatonin; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Structure-Activity Relationship | 1982 |
Effect of light and darkness on the in vivo release of N-acetylserotonin and melatonin by the retina of guinea pigs.
Topics: Animals; Darkness; Guinea Pigs; In Vitro Techniques; Light; Male; Melatonin; Retina; Retinal Pigments; Serotonin | 1982 |
Diurnal rhythms of immunoreactive N-acetylserotonin and melatonin in the serum of male rats.
Topics: Animals; Circadian Rhythm; Male; Melatonin; Radioimmunoassay; Rats; Serotonin | 1980 |
The level of N-acetylserotonin and melatonin in the brain of male rats: diurnal variations and effects of pinealectomy.
Topics: Animals; Brain Chemistry; Circadian Rhythm; Darkness; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Persistence of circadian rhythms of melatonin and N-acetylserotonin in the serum of rats after pinealectomy.
Topics: Animals; Circadian Rhythm; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Serotonin; Time Factors | 1981 |
Changes in the circadian rhythmicity of N- and O-acetyltransferase activities in the pineal gland of 38 day old male wistar rats when examined under white, red and green light.
Topics: Acetyltransferases; Animals; Circadian Rhythm; Light; Lighting; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1981 |
Clorgyline effect on pineal melatonin biosynthesis in Roman high- and low-avoidance rats.
Topics: Animals; Avoidance Learning; Clorgyline; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1994 |
Chronic effect of the irreversible and reversible selective MAO-A inhibitors on rat pineal melatonin biosynthesis.
Topics: Animals; Benzamides; Clorgyline; Female; Hydroxyindoleacetic Acid; Melatonin; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pineal Gland; Rats; Rats, Inbred F344; Serotonin; Time Factors | 1994 |
Nyctohemeral rhythm in the levels of S-adenosylmethionine in the rat pineal gland and its relationship to melatonin biosynthesis.
Topics: Animals; Chromatography, Liquid; Circadian Rhythm; Isoproterenol; Male; Melatonin; Photoperiod; Pineal Gland; Propranolol; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Serotonin; Time Factors | 1995 |
Stimulation of rat pineal melatonin biosynthesis by N-acetylserotonin.
Topics: Animals; Light; Male; Melatonin; Pineal Gland; Rats; Serotonin | 1994 |
Clorgyline effect on pineal melatonin biosynthesis in adrenalectomized rats pretreated with 6-hydroxydopamine.
Topics: Adrenalectomy; Animals; Clorgyline; Male; Melatonin; Oxidopamine; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Sympathectomy, Chemical | 1994 |
Chronopharmacological study of moclobemide effect on the rat pineal melatonin biosynthesis.
Topics: Animals; Benzamides; Circadian Rhythm; Female; Melatonin; Moclobemide; Monoamine Oxidase Inhibitors; Pineal Gland; Rats; Rats, Inbred F344; Serotonin; Time Factors | 1994 |
Duodenum is not a consistent source of melatonin in rats.
Topics: 5-Hydroxytryptophan; Animals; Chromatography; Duodenum; In Vitro Techniques; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Spectrometry, Fluorescence; Tryptophan | 1994 |
Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes.
Topics: 5-Methoxytryptamine; Acetates; Carbon Radioisotopes; Cholesterol; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Leukocytes, Mononuclear; Lipoproteins, LDL; Melatonin; Mevalonic Acid; Receptors, LDL; Serotonin; Tryptamines | 1994 |
Effect of an n-3 fatty acid-deficient diet on the adenosine-dependent melatonin release in cultured rat pineal.
Topics: Adenosine; Animals; Cells, Cultured; Dietary Fats; Fatty Acids; Fatty Acids, Omega-3; Female; Melatonin; Organ Culture Techniques; Phospholipids; Pineal Gland; Rats; Rats, Wistar; Serotonin | 1993 |
Melatonin and pineal neurochemicals in steers grazed on endophyte-infected tall fescue: effects of metoclopramide.
Topics: 5-Hydroxytryptophan; Acremonium; Animal Feed; Animals; Cattle; Dopamine; Fertilizers; Food Microbiology; Male; Melatonin; Metoclopramide; Nitrogen; Norepinephrine; Pineal Gland; Poaceae; Random Allocation; Serotonin | 1993 |
A distinct diurnal rhythm in hydroxyindole-O-methyltransferase (HIOMT) activity in the male albino rat.
Topics: Acetylserotonin O-Methyltransferase; Animals; Circadian Rhythm; Male; Melatonin; Photoperiod; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin | 1993 |
Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells.
Topics: 5-Methoxytryptamine; Animals; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Melanins; Melanoma, Experimental; Melatonin; Mice; Serotonin; Thymidine; Tumor Cells, Cultured | 1993 |
A melatonin binding site modulates the alpha 2-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding Sites; Cell Aggregation; Drug Synergism; Fishes; Melanophores; Melatonin; Norepinephrine; Pigments, Biological; Receptors, Adrenergic, alpha-2; Serotonin; Skin; Sympathetic Nervous System | 1996 |
Simultaneous determination of serotonin, N-acetylserotonin and melatonin in the pineal gland of the juvenile golden hamster by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Cricetinae; Electrochemistry; Melatonin; Mesocricetus; Pineal Gland; Serotonin | 1996 |
Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.
Topics: 5-Methoxytryptamine; Animals; Chromatography, High Pressure Liquid; Colforsin; Cricetinae; Gas Chromatography-Mass Spectrometry; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Serotonin; Skin; Tritium | 1996 |
Serotonin and N-acetylserotonin effects on pigment cells of the toad Bufo ictericus: pharmacological characterization of melatonin receptors.
Topics: alpha-MSH; Animals; Bufonidae; Chromatophores; Male; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Skin Pigmentation | 1996 |
Changes in pineal indoleamines in rats after single melatonin injections: evidence for a diurnal sensitivity to melatonin.
Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin | 1996 |
Central melatonin receptors in red deer (Cervus elaphus).
Topics: Animals; Autoradiography; Binding Sites; Brain; Deer; In Vitro Techniques; Melatonin; NAD; Pituitary Gland; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin | 1996 |
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines | 1997 |
Inhibition of lipid peroxidation by N-acetylserotonin and its role in retinal physiology.
Topics: Animals; Antioxidants; Chromans; Free Radical Scavengers; Humans; In Vitro Techniques; Lipid Peroxidation; Melatonin; Photoreceptor Cells; Pineal Gland; Retina; Serotonin; Vitamin E | 1997 |
Hydroxyindole-O-methyltransferase activity assay using high-performance liquid chromatography with fluorometric detection: determination of melatonin enzymatically formed from N-acetylserotonin and S-adenosyl-L-methionine.
Topics: Acetylserotonin O-Methyltransferase; Animals; Chromatography, High Pressure Liquid; Female; Kinetics; Melatonin; Pineal Gland; Rats; Rats, Wistar; S-Adenosylmethionine; Serotonin; Spectrometry, Fluorescence | 1997 |
Hydroxyindole-O-methyltransferase activity in the silkworm (Bombyx mori).
Topics: Acetylserotonin O-Methyltransferase; Animals; Bombyx; Brain; Circadian Rhythm; Darkness; Kinetics; Larva; Light; Melatonin; Nerve Tissue Proteins; Radioimmunoassay; S-Adenosylmethionine; Serotonin | 1997 |
[Melatonin and coronary heart disease].
Topics: Circadian Rhythm; Coronary Disease; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Reference Values; Secretory Rate; Serotonin; Sleep Stages; Sympathetic Nervous System | 1997 |
Indoleamine metabolism in the pineal gland of the Chinese hamster, Cricetulus griseus.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Biogenic Monoamines; Circadian Rhythm; Cricetinae; Cricetulus; Dopamine; Male; Melatonin; Pineal Gland; Serotonin; Tritium; Tryptamines; Tryptophan | 1998 |
Effect of estrogen on melatonin synthesis in female peripubertal rats.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Chromatography, High Pressure Liquid; Circadian Rhythm; Estradiol; Female; Injections, Subcutaneous; Melatonin; Ovariectomy; Ovary; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Sexual Maturation | 1998 |
N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB.
Topics: Animals; Cell Survival; Cerebellar Nuclei; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hydrogen Peroxide; Melatonin; N-Methylaspartate; Neuroblastoma; Neurons; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serotonin; Tumor Cells, Cultured | 1998 |
Clorgyline effect on pineal melatonin biosynthesis in rats with lesioned suprachiasmatic nuclei.
Topics: Animals; Clorgyline; Darkness; Hydroxyindoleacetic Acid; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Suprachiasmatic Nucleus | 1998 |
The effect of MAO-A inhibition and cold-immobilization stress on N-acetylserotonin and melatonin in SHR and WKY rats.
Topics: Animals; Clorgyline; Cold Temperature; Hydroxyindoleacetic Acid; Isatin; Isoenzymes; Male; Melatonin; Monoamine Oxidase Inhibitors; Pineal Gland; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Restraint, Physical; Serotonin; Species Specificity | 1998 |
Estrogen modulates the nocturnal synthesis of melatonin in peripubertal female rats.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Chromatography, High Pressure Liquid; Dark Adaptation; Estrogens; Female; Melatonin; Ovariectomy; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Sexual Maturation | 1998 |
Melatonin receptor pharmacology: toward subtype specificity.
Topics: 3T3 Cells; 5-Methoxytryptamine; Acetylation; Animals; Binding Sites; Binding, Competitive; Clone Cells; Cloning, Molecular; GTP-Binding Proteins; Humans; Ligands; Melanocytes; Melanophores; Melatonin; Methylation; Mice; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serotonin; Species Specificity; Structure-Activity Relationship; Transfection; Tryptamines; Xenopus laevis | 1997 |
Vitamin E consumption induced by oxidative stress in red blood cells is enhanced by melatonin and reduced by N-acetylserotonin.
Topics: Antioxidants; Benzene Derivatives; Electrochemistry; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Lipid Peroxidation; Melatonin; Models, Biological; Oxidants; Oxidation-Reduction; Oxidative Stress; Serotonin; Vitamin E | 1998 |
Changes with age in daytime and nighttime contents of melatonin, indoleamines, and catecholamines in the pineal gland: a comparative study in rat and Syrian hamster.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Catecholamines; Circadian Rhythm; Cricetinae; Dopamine; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mesocricetus; Norepinephrine; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin | 1998 |
Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants.
Topics: Animals; Antioxidants; Cell Survival; Clone Cells; Dopamine Antagonists; Gene Expression Regulation; Glutathione; Haloperidol; Hippocampus; Melatonin; Mice; Neurons; Neuroprotective Agents; Neurotoxins; NF-kappa B; Oxidative Stress; Peroxides; Serotonin; Transcriptional Activation; Vitamin E | 1998 |
Indoleamine analogs as probes of the substrate selectivity and catalytic mechanism of serotonin N-acetyltransferase.
Topics: Acetyl Coenzyme A; Animals; Arylamine N-Acetyltransferase; Catalysis; Circadian Rhythm; Hydrogen-Ion Concentration; Indoles; Kinetics; Melatonin; Models, Chemical; Propionates; Serotonin; Sheep; Substrate Specificity; Tryptamines | 1998 |
Day and night dysfunction in intraretinal melatonin and related indoleamines metabolism, correlated with the development of glaucoma-like disorder in an avian model.
Topics: Acetylserotonin O-Methyltransferase; Aging; Amines; Animals; Circadian Rhythm; Coturnix; Glaucoma; Hydroxyindoleacetic Acid; Indoles; Melatonin; Mutation; Reference Values; Retina; Serotonin | 1998 |
The role of the retrochiasmatic area in the control of pineal metabolism.
Topics: Animals; Excitatory Amino Acid Antagonists; Ibotenic Acid; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Retina; Serotonin; Suprachiasmatic Nucleus | 1999 |
Characterization of membrane melatonin receptor in mouse peritoneal macrophages: inhibition of adenylyl cyclase by a pertussis toxin-sensitive G protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Blotting, Western; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Iodine Radioisotopes; Kinetics; Macrophages, Peritoneal; Melatonin; Mice; Neuroimmunomodulation; Pertussis Toxin; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Signal Transduction; Tryptamines; Virulence Factors, Bordetella | 1999 |
N-acetylserotonin is a better extra- and intracellular antioxidant than melatonin.
Topics: Adult; Antioxidants; Cell Death; Cell-Free System; Cells, Cultured; Humans; Intracellular Fluid; Leukocytes, Mononuclear; Male; Melatonin; Oxidation-Reduction; Reactive Oxygen Species; Rhodamines; Serotonin | 1999 |
Melatonin, its precursors, and synthesizing enzyme activities in the human ovary.
Topics: Acetyl Coenzyme A; Acetylserotonin O-Methyltransferase; Adult; Arylamine N-Acetyltransferase; Chromatography, High Pressure Liquid; Female; Fluorometry; Humans; Kinetics; Linear Models; Melatonin; Middle Aged; Ovary; Protein Precursors; Serotonin; Tryptamines; Tryptophan | 1999 |
Pineal indoleamines and vitamin E reduce nitric oxide-induced lipid peroxidation in rat retinal homogenates.
Topics: Animals; Antioxidants; Carbolines; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitric Oxide; Nitroprusside; Pineal Gland; Rats; Rats, Sprague-Dawley; Retina; Serotonin; Vitamin E | 1999 |
Melatonin and its precursors scavenge nitric oxide.
Topics: 5-Hydroxytryptophan; Cadmium; Copper; Free Radical Scavengers; Hydrazines; Indicators and Reagents; Kinetics; Melatonin; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Serotonin; Tryptophan | 1999 |
N-acetylserotonin, melatonin and their derivatives improve cognition and protect against beta-amyloid-induced neurotoxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Aziridines; Cells, Cultured; Cerebellum; Choline; Cognition; Drug Evaluation, Preclinical; Male; Melatonin; Neuromuscular Blocking Agents; Nootropic Agents; Rats; Rats, Wistar; Serotonin | 1999 |
Anxiolytic-like properties of melatonin receptor agonists in mice: involvement of mt1 and/or MT2 receptors in the regulation of emotional responsiveness.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Heterocyclic Compounds, 2-Ring; Male; Melatonin; Metallothionein 3; Mice; Mice, Inbred C3H; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Tryptamines | 2000 |
Purinergic and noradrenergic cotransmission in the rat pineal gland.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Melatonin; Norepinephrine; Pineal Gland; Propranolol; Pyridoxal Phosphate; Rats; Rats, Wistar; Serotonin; Suramin; Synaptic Transmission; Time Factors | 2000 |
Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbolines; Carcinogens; Cattle; Chromium; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Indoles; Melatonin; Serotonin | 2000 |
Characterization of the protective effects of melatonin and related indoles against alpha-naphthylisothiocyanate-induced liver injury in rats.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Cell Membrane; Indoles; Lipid Peroxidation; Liver; Male; Melatonin; Microsomes, Liver; Neutrophils; Rats; Rats, Sprague-Dawley; Serotonin | 2001 |
Lesions of the dorsomedial hypothalamic nucleus do not influence the daily profile of pineal metabolism in rats.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Dorsomedial Hypothalamic Nucleus; Electrosurgery; Hydroxyindoleacetic Acid; Hypothalamus; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin; Tryptophan | 2001 |
Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin.
Topics: Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP1A2; Enzyme Inhibitors; Fluvoxamine; Humans; Melatonin; Microsomes, Liver; Serotonin; Theophylline | 2001 |
Mechanistic studies on the alkyltransferase activity of serotonin N-acetyltransferase.
Topics: Alkyl and Aryl Transferases; Animals; Arylamine N-Acetyltransferase; Binding Sites; Catalysis; Cells, Cultured; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kinetics; Melatonin; Mutation; Pineal Gland; Recombinant Proteins; Serotonin; Tryptamines | 2001 |
Relative efficacies of indole antioxidants in reducing autoxidation and iron-induced lipid peroxidation in hamster testes.
Topics: Animals; Antioxidants; Cricetinae; Hydroxyindoleacetic Acid; Indoles; Iron; Lipid Peroxidation; Male; Melatonin; Mesocricetus; Oxidation-Reduction; Propionates; Serotonin; Testicular Neoplasms; Testis | 2001 |
Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models.
Topics: Aging; Aldehydes; Animals; Antioxidants; Body Weight; Brain; Female; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Serotonin | 2001 |
Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.
Topics: Animals; Arterioles; Blood Flow Velocity; Cell Adhesion; Dose-Response Relationship, Drug; Leukocytes; Male; Melatonin; Microcirculation; Rats; Rats, Wistar; Serotonin; Tetrahydronaphthalenes; Tryptamines | 2001 |
[Morphofunctional changes in the pineal gland during adaptation to hypothermia].
Topics: 5-Methoxytryptamine; Adaptation, Physiological; Animals; Cold Temperature; Fluorometry; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin | 2001 |
Serotoninergic and melatoninergic systems are fully expressed in human skin.
Topics: Acetylserotonin O-Methyltransferase; Arylamine N-Acetyltransferase; Cell Line; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Melanocytes; Melanoma; Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Skin; Tryptophan Hydroxylase; Tumor Cells, Cultured; Ultraviolet Rays | 2002 |
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors.
Topics: 5-Methoxytryptamine; Amyloid beta-Peptides; Animals; Antioxidants; Cells, Cultured; Cyclic N-Oxides; Free Radical Scavengers; Hippocampus; Humans; Melatonin; Neuroblastoma; Neurons; Neuroprotective Agents; Nitrogen Oxides; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin | 2002 |
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs.
Topics: 5-Methoxytryptamine; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Molecular Biology; Oxidation-Reduction; Serotonin; Solubility; Structure-Activity Relationship; Superoxides; Tryptamines | 2002 |
Melatonin biological activity and binding sites in human melanoma cells.
Topics: Binding Sites; Binding, Competitive; Cell Division; Humans; Iodine Radioisotopes; Melanoma; Melatonin; Monophenol Monooxygenase; Prazosin; Serotonin; Tryptamines; Tumor Cells, Cultured | 2003 |
Functional activity of serotoninergic and melatoninergic systems expressed in the skin.
Topics: 5-Methoxytryptamine; Amino Acid Sequence; Apoptosis; Base Sequence; Cell Division; Cells, Cultured; Gene Expression; Humans; Melatonin; Phenotype; Pituitary Gland; Protein Isoforms; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Skin | 2003 |
Differential effects of lipopolysaccharide on lipid peroxidation in F344N, SHR rats and BALB/c mice, and protection of melatonin and NAS against its toxicity.
Topics: Alkenes; Animals; Brain; Female; Kidney; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Malondialdehyde; Melatonin; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Rats; Rats, Inbred F344; Rats, Inbred SHR; Serotonin; Tissue Extracts | 2003 |
Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin.
Topics: Melatonin; Serotonin | 1960 |
Enzymatic O-methylation of N-acetylserotonin to melatonin.
Topics: Acetylserotonin O-Methyltransferase; Melatonin; Methionine; Methylation; Pineal Gland; S-Adenosylmethionine; Serotonin; Transferases | 1960 |
Protective effect of indoleamines on in vitro ascorbate-Fe2+ dependent lipid peroxidation of rod outer segment membranes of bovine retina.
Topics: Animals; Ascorbic Acid; Cattle; Free Radical Scavengers; Iron; Lipid Metabolism; Lipid Peroxidation; Melatonin; Reactive Oxygen Species; Rod Cell Outer Segment; Serotonin; Time Factors | 2003 |
Melatonin and N-acetyl-serotonin cross the red blood cell membrane and evoke calcium mobilization in malarial parasites.
Topics: Animals; Calcium; Calcium Signaling; Cell Membrane Permeability; Erythrocyte Membrane; Female; Host-Parasite Interactions; Melatonin; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Plasmodium chabaudi; Serotonin | 2003 |
Involvement of the pineal gland in diurnal cocaine reward in mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cell Cycle Proteins; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Gene Expression; Injections, Intraperitoneal; Melatonin; Mice; Mice, Inbred C3H; Mice, Knockout; Nuclear Proteins; Period Circadian Proteins; Pineal Gland; Serotonin | 2004 |
Diurnal rhythms in cocaine sensitization and in Period1 levels are common across rodent species.
Topics: Animals; Blotting, Western; Cell Cycle Proteins; Circadian Rhythm; Cocaine; Melatonin; Mice; Mice, Inbred AKR; Mice, Inbred CBA; Motor Activity; Neostriatum; Nuclear Proteins; Period Circadian Proteins; Pineal Gland; Rats; Rats, Sprague-Dawley; Seasons; Serotonin; Species Specificity | 2004 |
Retinal ganglion cells are autonomous circadian oscillators synthesizing N-acetylserotonin during the day.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Brain; Chick Embryo; Chickens; Circadian Rhythm; Cyclic AMP; In Situ Hybridization; Melatonin; Oscillometry; Radioimmunoassay; Retina; Retinal Ganglion Cells; RNA; RNA, Messenger; Serotonin; Time Factors; Tryptophan | 2004 |
Corticosterone modulates noradrenaline-induced melatonin synthesis through inhibition of nuclear factor kappa B.
Topics: Animals; Base Sequence; Corticosterone; Dexamethasone; DNA; Female; Hormone Antagonists; Leupeptins; Male; Melatonin; Mifepristone; NF-kappa B; Norepinephrine; Organ Culture Techniques; Pineal Gland; Pyrrolidines; Rats; Rats, Wistar; Receptors, Glucocorticoid; Serotonin; Thiocarbamates | 2005 |
N-acetyltransferase is not the rate-limiting enzyme of melatonin synthesis at night.
Topics: Acetylserotonin O-Methyltransferase; Amino Acid Substitution; Animals; Circadian Rhythm; Male; Melatonin; Pineal Gland; Point Mutation; Rats; Rats, Sprague-Dawley; Serotonin | 2005 |
Immune-modulating effects of melatonin, N-acetylserotonin, and N-acetyldopamine.
Topics: Antioxidants; Cell Line; Cytokines; Dopamine; HL-60 Cells; Humans; Immunologic Factors; Melatonin; Monocytes; Neutrophils; Serotonin; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Free-running rhythms of pineal circadian output.
Topics: Animals; Biological Clocks; Body Temperature; Circadian Rhythm; Male; Melatonin; Microdialysis; Motor Activity; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors | 2005 |
Analysis of melatonin using a pH- and temperature-responsive aqueous chromatography system.
Topics: Acrylic Resins; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Ion Exchange Resins; Melatonin; Serotonin; Temperature; Tryptophan | 2007 |
Ultrastructural and hormonal changes in the pineal-testicular axis following arecoline administration in rats.
Topics: Animals; Arecoline; Cholinergic Agonists; Fructose; Injections, Intraperitoneal; Leydig Cells; Male; Melatonin; N-Acetylneuraminic Acid; Photoperiod; Pineal Gland; Prostate; Rats; Rats, Wistar; Serotonin; Testis; Testosterone | 2007 |
The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in omega-3 polyunsaturated fatty acids.
Topics: 5-Methoxytryptamine; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Cell-Free System; Docosahexaenoic Acids; Fatty Acids, Omega-3; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Lipids; Luminescent Measurements; Melatonin; Oxidation-Reduction; Picrates; Reactive Oxygen Species; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan | 2007 |
Melatonin and N-acetyl serotonin inhibit selectively enzymatic and non-enzymatic lipid peroxidation of rat liver microsomes.
Topics: Animals; Ascorbic Acid; Female; Ferrous Compounds; Lipid Metabolism; Lipid Peroxidation; Melatonin; Microsomes, Liver; NADP; Rats; Serotonin; Time Factors | 2007 |
Photocatalytic mechanisms of indoleamine destruction by the quinalphos metabolite 2-hydroxyquinoxaline: a study on melatonin and its precursors serotonin and N-acetylserotonin.
Topics: Antioxidants; Humans; Light; Melatonin; Organothiophosphorus Compounds; Oxidants; Oxidation-Reduction; Oxygen; Photochemistry; Quinoxalines; Serotonin | 2007 |
Protective effects of melatonin and N-acetylserotonin on aflatoxin B1-induced lipid peroxidation in rats.
Topics: Aflatoxin B1; Animals; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Organ Specificity; Protective Agents; Rats; Rats, Wistar; Serotonin | 2008 |
Effect of methylene blue and related redox dyes on monoamine oxidase activity; rat pineal content of N-acetylserotonin, melatonin, and related indoles; and righting reflex in melatonin-primed frogs.
Topics: Animals; Anura; Enzyme Inhibitors; Melatonin; Methylene Blue; Monoamine Oxidase; Oxidation-Reduction; Pineal Gland; Rats; Reflex; Serotonin | 2007 |
Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arylalkylamine N-Acetyltransferase; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chromatography, High Pressure Liquid; Cyclic CMP; Dose-Response Relationship, Drug; Electrochemistry; In Vitro Techniques; Isoproterenol; Melatonin; Nifedipine; Norepinephrine; Pineal Gland; Rats; Rats, Wistar; Serotonin; Tryptophan Hydroxylase | 2008 |
Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kinetics; Kynuramine; Liver; Male; Melatonin; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Serotonin; Spectrometry, Mass, Electrospray Ionization | 2008 |
Relative efficacies of alpha-tocopherol, N-acetyl-serotonin, and melatonin in reducing non-enzymatic lipid peroxidation of rat testicular microsomes and mitochondria.
Topics: alpha-Tocopherol; Animals; Antioxidants; Arachidonic Acid; Fatty Acids, Unsaturated; Lipid Peroxidation; Male; Melatonin; Microsomes; Mitochondria; Rats; Rats, Wistar; Serotonin; Testis | 2009 |
Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Melatonin; Oxidative Stress; Schizophrenia; Serotonin; Tryptophan; Young Adult | 2010 |
The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19).
Topics: Acetylserotonin O-Methyltransferase; Arylalkylamine N-Acetyltransferase; Cell Line; Gene Expression Regulation; Humans; Melatonin; Receptors, Melatonin; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2009 |
Effect of selected antioxidants in beta-cyfluthrin-induced oxidative stress in human erythrocytes in vitro.
Topics: Antioxidants; Erythrocytes; Hemoglobins; Hemolysis; Humans; In Vitro Techniques; Insecticides; Lipid Peroxidation; Malondialdehyde; Melatonin; Nitriles; Oxidative Stress; Pyrethrins; Quercetin; Rutin; Serotonin; Superoxide Dismutase | 2010 |
N-acetylserotonin activates TrkB receptor in a circadian rhythm.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cell Line; Circadian Rhythm; Depression; Hippocampus; Humans; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Receptor, trkB; Retina; Serotonin | 2010 |
Enhanced production of melatonin by ectopic overexpression of human serotonin N-acetyltransferase plays a role in cold resistance in transgenic rice seedlings.
Topics: Analysis of Variance; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Chlorophyll; Cold-Shock Response; Humans; Melatonin; Oryza; Phenotype; Plants, Genetically Modified; Rhizobium; Seedlings; Serotonin | 2010 |
N-acetylserotonin reduces lipopolysaccharide-induced lipid peroxidation in vitro more effectively than melatonin.
Topics: Analysis of Variance; Animals; Brain; Kidney; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Malondialdehyde; Melatonin; Rats; Rats, Wistar; Serotonin | 2010 |
In vitro effects of 5-hydroxytryptophan, indoleamines and leptin on arylalkylamine N-acetyltransferase (AA-NAT) activity in pineal organ of the fish, Clarias gariepinus (Burchell, 1822) during different phases of the breeding cycle.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Second-Generation; Antioxidants; Arylalkylamine N-Acetyltransferase; Breeding; Catfishes; Leptin; Melatonin; Pineal Gland; Radioimmunoassay; Serotonin; Serotonin Receptor Agonists | 2010 |
Melatonin administration after pilocarpine-induced status epilepticus: a new way to prevent or attenuate postlesion epilepsy?
Topics: Analysis of Variance; Animals; Antioxidants; Cell Death; Disease Models, Animal; Hippocampus; Male; Melatonin; Pilocarpine; Rats; Rats, Wistar; Serotonin; Statistics as Topic; Status Epilepticus | 2011 |
Quantitation of melatonin and n-acetylserotonin in human plasma by nanoflow LC-MS/MS and electrospray LC-MS/MS.
Topics: Adult; Child; Child, Preschool; Chromatography, Liquid; Female; Humans; Male; Melatonin; Nanotechnology; Reproducibility of Results; Serotonin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system.
Topics: 5-Methoxytryptamine; Antioxidants; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Lipid Peroxidation; Lysosomes; Melatonin; Picrates; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan | 2012 |
Pineal arylalkylamine N-acetyltransferase (Aanat) gene expression as a target of inflammatory mediators in the chicken.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylalkylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Dopa Decarboxylase; Down-Regulation; Inflammation Mediators; Male; Melatonin; Peritonitis; Pineal Gland; RNA, Messenger; Serotonin; Thioglycolates; Tryptophan Hydroxylase | 2012 |
The arylalkylamine-N-acetyltransferase (AANAT) acetylates dopamine in the digestive tract of goldfish: a role in intestinal motility.
Topics: Acetylation; Animals; Arylalkylamine N-Acetyltransferase; Circadian Rhythm; Dopamine; Enzyme Inhibitors; Gastrointestinal Motility; Gastrointestinal Tract; Goldfish; In Vitro Techniques; Liver; Melatonin; Retina; Serotonin; Tryptamines | 2013 |
RGS2 is a feedback inhibitor of melatonin production in the pineal gland.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Cyclic AMP; Enzyme Induction; Feedback, Physiological; Female; Melatonin; Norepinephrine; Pineal Gland; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; RGS Proteins; RNA, Messenger; Serotonin; Time Factors | 2013 |
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.
Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Keratin-10; Keratin-14; Keratinocytes; Kinetics; Kynuramine; Melanocytes; Melanoma; Melatonin; Metabolic Networks and Pathways; Serotonin; Skin; Spectrometry, Mass, Electrospray Ionization; Swine | 2013 |
Age-related changes in melatonin release in the murine distal colon.
Topics: Aging; Animals; Central Nervous System Depressants; Colon; Electrochemical Techniques; Enterochromaffin Cells; Gastrointestinal Motility; Intestinal Mucosa; Male; Melatonin; Mice; Mice, Inbred C57BL; N-Terminal Acetyltransferases; Serotonin | 2013 |
Elevated production of melatonin in transgenic rice seeds expressing rice tryptophan decarboxylase.
Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Melatonin; Oryza; Plants, Genetically Modified; Seeds; Serotonin; Tryptamines | 2014 |
Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.
Topics: Cell Line; DNA Damage; Humans; Keratinocytes; Kynuramine; Melatonin; Serotonin; Ultraviolet Rays | 2014 |
Diurnal profiles of melatonin synthesis-related indoles, catecholamines and their metabolites in the duck pineal organ.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Ducks; Indoles; Melatonin; Pineal Gland; Serotonin | 2014 |
Caffeic acid O-methyltransferase is involved in the synthesis of melatonin by methylating N-acetylserotonin in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Melatonin; Methyltransferases; Serotonin | 2014 |
Adrenergic activation of melatonin secretion in ovine pineal explants in short-term superfusion culture occurs via protein synthesis independent and dependent phenomena.
Topics: Animals; Anisomycin; Cycloheximide; Female; Humans; Melatonin; Norepinephrine; Pineal Gland; Protein Biosynthesis; Rats, Wistar; Receptors, Adrenergic; Serotonin; Sheep; Time Factors; Tissue Culture Techniques | 2014 |
The serotonin-N-acetylserotonin-melatonin pathway as a biomarker for autism spectrum disorders.
Topics: Adolescent; Adult; Biomarkers; Child; Child Development Disorders, Pervasive; Female; Humans; Male; Melatonin; Parents; Serotonin; Siblings; Signal Transduction | 2014 |
Melatonin has differential effects on age-induced stoichiometric changes in daily chronomics of serotonin metabolism in SCN of male Wistar rats.
Topics: 5-Hydroxytryptophan; Aging; Animals; Chronobiology Phenomena; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Melatonin; Models, Animal; Rats; Rats, Wistar; Serotonin; Suprachiasmatic Nucleus | 2015 |
N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin.
Topics: Copper; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Oxidative Stress; Peroxides; Serotonin; Solvents; Water | 2015 |
Administration of N-acetylserotonin and melatonin alleviate chronic ketamine-induced behavioural phenotype accompanying BDNF-independent and dependent converging cytoprotective mechanisms in the hippocampus.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Hippocampus; Ketamine; Melatonin; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Phenotype; Random Allocation; Receptor, trkB; Receptors, Melatonin; Receptors, N-Methyl-D-Aspartate; Serotonin | 2016 |
Glucose-based microbial production of the hormone melatonin in yeast Saccharomyces cerevisiae.
Topics: Animals; Batch Cell Culture Techniques; Biosynthetic Pathways; Culture Media; Fermentation; Glucose; Humans; Industrial Microbiology; Melatonin; Metabolic Engineering; Saccharomyces cerevisiae; Serotonin | 2016 |
High membrane permeability for melatonin.
Topics: Cell Line; Cell Membrane Permeability; Fluorescence; Fura-2; Humans; Melatonin; Pineal Gland; Serotonin | 2016 |
Adenosine triphosphate inhibits melatonin synthesis in the rat pineal gland.
Topics: Acetylserotonin O-Methyltransferase; Adenosine Triphosphate; Animals; Female; Male; Melatonin; NF-kappa B; Pineal Gland; Rats; Rats, Wistar; Receptors, Purinergic P2Y1; Serotonin; Type C Phospholipases | 2016 |
Ultrahigh-Performance Liquid Chromatography (UHPLC)-Tandem Mass Spectrometry (MS/MS) Quantification of Nine Target Indoles in Sparkling Wines.
Topics: Chromatography, High Pressure Liquid; Food Analysis; Indoles; Limit of Detection; Melatonin; Serotonin; Tandem Mass Spectrometry; Wine | 2016 |
Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Melatonin; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Serotonin; Treatment Outcome | 2016 |
Quantification of the neurotransmitters melatonin and N-acetyl-serotonin in human serum by supercritical fluid chromatography coupled with tandem mass spectrometry.
Topics: Chromatography, Supercritical Fluid; Humans; Liquid-Liquid Extraction; Melatonin; Neurotransmitter Agents; Serotonin; Tandem Mass Spectrometry | 2016 |
TRPV4 Stimulation Induced Melatonin Secretion by Increasing Arylalkymine N-acetyltransferase (AANAT) Protein Level.
Topics: Arylalkylamine N-Acetyltransferase; Blotting, Western; Cell Line; Ciliary Body; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Leucine; Melatonin; Microscopy, Confocal; Models, Biological; Phosphorylation; Serotonin; Sulfonamides; Time Factors; TRPV Cation Channels | 2017 |
Rice histone deacetylase 10 and Arabidopsis histone deacetylase 14 genes encode N-acetylserotonin deacetylase, which catalyzes conversion of N-acetylserotonin into serotonin, a reverse reaction for melatonin biosynthesis in plants.
Topics: Arabidopsis; Arylalkylamine N-Acetyltransferase; Histone Deacetylases; Melatonin; Oryza; Phylogeny; Plant Proteins; Serotonin | 2018 |
Heritability of the melatonin synthesis variability in autism spectrum disorders.
Topics: Adolescent; Adult; Arylalkylamine N-Acetyltransferase; Autism Spectrum Disorder; Child; Endophenotypes; Family; Female; Humans; Intellectual Disability; Male; Melatonin; Middle Aged; Serotonin; Siblings; Sleep Wake Disorders | 2017 |
Heterologous expression of ZjOMT from Zoysia japonica in Escherichia coli confers aluminum resistance through melatonin production.
Topics: Aluminum; Cloning, Molecular; Escherichia coli; Gene Expression Regulation, Enzymologic; Melatonin; Methyltransferases; Oxidative Stress; Poaceae; Serotonin | 2018 |
Arecoline inhibits pineal-testis function in experimentally induced hypothyroid rats.
Topics: Animals; Antithyroid Agents; Arecoline; Endoplasmic Reticulum; Fructose; Hypothyroidism; Leydig Cells; Male; Melatonin; N-Acetylneuraminic Acid; Pineal Gland; Propylthiouracil; Rats; Serotonin; Testis; Testosterone; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2020 |
Effects of Streptozotocin-Induced Diabetes on the Pineal Gland in the Domestic Pig.
Topics: Animals; Biomarkers; Catecholamines; Diabetes Mellitus, Experimental; Melatonin; Pineal Gland; Serotonin; Streptozocin; Sus scrofa; Swine; Swine Diseases | 2018 |
Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression.
Topics: Acetylserotonin O-Methyltransferase; Adenosine Triphosphate; Animals; Cluster Analysis; Female; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seasons; Sequence Analysis, RNA; Serotonin; Transcriptome | 2018 |
Significantly improved catalytic efficiency of caffeic acid O-methyltransferase towards N-acetylserotonin by strengthening its interactions with the unnatural substrate's terminal structure.
Topics: Amino Acid Substitution; Arabidopsis; Binding Sites; Caffeic Acids; Catalysis; Melatonin; Methyltransferases; Molecular Dynamics Simulation; Molecular Structure; Protein Engineering; Serotonin; Structure-Activity Relationship; Thermodynamics | 2019 |
Two indoleamines are secreted from rat pineal gland at night and act on melatonin receptors but are not night hormones.
Topics: Animals; Circadian Rhythm; HEK293 Cells; Humans; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serotonin; Tryptamines | 2020 |
Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cells.
Topics: Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Epidermis; Female; Fibroblasts; Humans; Keratinocytes; Male; Melatonin; Middle Aged; Serotonin; Skin Aging | 2020 |
Serotonin and its metabolites reduce oxidative stress in murine RAW264.7 macrophages and prevent inflammation.
Topics: Animals; Antioxidants; Cytokines; Inflammation; Macrophages; Melatonin; Mice; Nitric Oxide; Oxidative Stress; RAW 264.7 Cells; Reactive Oxygen Species; Serotonin | 2020 |
Occurrence of melatonin and indolic compounds derived from l-tryptophan yeast metabolism in fermented wort and commercial beers.
Topics: Beer; Beverages; Chromatography, High Pressure Liquid; Fermentation; Food Analysis; Food Storage; Indoles; Melatonin; Saccharomyces cerevisiae; Serotonin; Temperature; Tryptophan | 2020 |
Sex and race differences of cerebrospinal fluid metabolites in healthy individuals.
Topics: Adult; alpha-Tocopherol; Cerebrospinal Fluid; Cysteine; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Melatonin; Metabolome; Metabolomics; Race Factors; Serotonin; Sex Characteristics; Sex Factors; Uric Acid; Xanthine; Xanthines | 2021 |
Melatonin synthesis genes N-acetylserotonin methyltransferases evolved into caffeic acid O-methyltransferases and both assisted in plant terrestrialization.
Topics: Acetylserotonin O-Methyltransferase; Ecosystem; Melatonin; Methyltransferases; Phylogeny; Serotonin | 2021 |
Inhibition of Rice Serotonin
Topics: Arylalkylamine N-Acetyltransferase; Cadmium; Dose-Response Relationship, Drug; Melatonin; Oryza; Plant Proteins; Recombinant Proteins; Salicylates; Seedlings; Serotonin | 2021 |
Embryonic Development of Avian Pineal Secretory Activity-A Lesson from the Goose Pineal Organs in Superfusion Culture.
Topics: 5-Hydroxytryptophan; Animals; Biomarkers; Embryonic Development; Geese; Gene Expression Regulation, Developmental; Light; Melatonin; Norepinephrine; Organogenesis; Photoperiod; Pineal Gland; Serotonin; Tissue Culture Techniques | 2021 |
Overexpression of MdASMT9, an N-acetylserotonin methyltransferase gene, increases melatonin biosynthesis and improves water-use efficiency in transgenic apple.
Topics: Acetylserotonin O-Methyltransferase; Malus; Melatonin; Serotonin; Water | 2022 |
Brain Damage-linked ATP Promotes P2X7 Receptors Mediated Pineal N-acetylserotonin Release.
Topics: Acetylserotonin O-Methyltransferase; Adenosine Triphosphate; Animals; Melatonin; NAD; Norepinephrine; Pineal Gland; Rats; Receptors, Purinergic P2X7; Serotonin | 2022 |
Changes in the Metabolic Profile of Melatonin Synthesis-Related Indoles during Post-Embryonic Development of the Turkey Pineal Organ.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Circadian Rhythm; Embryonic Development; Hydroxyindoleacetic Acid; Indoles; Melatonin; Metabolome; Pineal Gland; Serotonin; Tryptophan | 2022 |
Two-Dimensional Thin Layer Chromatography of Melatonin and Related Compounds.
Topics: Arylalkylamine N-Acetyltransferase; Chromatography, Thin Layer; Complex Mixtures; Culture Media; Humans; Hydroxytryptophol; Melatonin; Pineal Gland; Serotonin; Tryptophan | 2022 |
N-Acetylserotonin is an oxidation-responsive activator of Nrf2 ameliorating colitis in rats.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Heme Oxygenase-1; Melatonin; NF-E2-Related Factor 2; Rats | 2023 |
In vitro deacetylation of N-acetylserotonin by arylacetamide deacetylase.
Topics: Animals; Carboxylic Ester Hydrolases; Humans; Mammals; Melatonin; Mice; Physostigmine; Serotonin | 2023 |
Arylalkylamine N-acetyltransferase (AANAT): Blue light induction, nuclear translocation, and potential role in the survival of chicken retina neuronal cells.
Topics: Animals; Arylalkylamine N-Acetyltransferase; Chick Embryo; Chickens; Circadian Rhythm; Light; Melatonin; Pineal Gland; Retina; RNA, Messenger; Serotonin | 2023 |