n-acetylserotonin and 6-hydroxymelatonin

n-acetylserotonin has been researched along with 6-hydroxymelatonin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's6 (30.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Little, JC; Reiter, RJ; Rudeen, PK; Sackman, JW; Waring, PJ1
Kuchel, GA; Sherman, RL; Zigmond, RE1
Flügge, G; Laitinen, JT; Saavedra, JM1
Hill, BT; Shellard, SA; Whelan, RD1
Leone, RM; Silman, RE; Young, IM1
Francis, PL; Leone, AM; McKenzie-Gray, B1
Francis, PL; Leone, AM; Silman, RE1
Francis, P; Leone, RM; Silman, RE; Stovell, P; Young, IM1
Leone, RM; Silman, RE1
Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD1
Garratt, PJ; Pickering, H; Sugden, D; Teh, MT1
Calvo, JR; García-Pergañeda, A; Guerrero, JM; Paz Romero, M; Pozo, D; Rafii-El-Idrissi, M1
Garcia, JJ; Manchester, LC; Qi, W; Reiter, RJ; Siu, AW; Tan, DX1
Arand, M; Friedberg, T; Härtter, S; Hiemke, C; Oesch, F; Wang, X; Weigmann, H1
Antonova, M; Korik, E; Semak, I; Slominski, A; Wortsman, J1
Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T1
Hanna, S; Janjetovic, Z; Jarrett, SG; Kim, TK; Nahmias, ZP; Reiter, RJ; Slominski, AT1
Álvarez-Diduk, R; Galano, A; Reiter, RJ; Tan, DX1

Other Studies

20 other study(ies) available for n-acetylserotonin and 6-hydroxymelatonin

ArticleYear
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi

1998
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
The effects of pineal indoles given late in the light period on reproductive organs and pituitary prolactin levels in male golden hamsters.
    Hormone research, 1977, Volume: 8, Issue:2

    Topics: Animals; Body Weight; Cricetinae; Genitalia, Male; Indoles; Light; Male; Melatonin; Mesocricetus; Organ Size; Periodicity; Pineal Gland; Pituitary Gland; Prolactin; Serotonin; Testis

1977
Recovery of function following unilateral denervation, but not unilateral decentralization, of the pineal gland as indicated by measurements of pineal melatonin content and urinary melatonin metabolites.
    Neuroscience, 1990, Volume: 37, Issue:2

    Topics: Animals; Arylamine N-Acetyltransferase; Central Nervous System; Circadian Rhythm; Denervation; Electrophysiology; Male; Melatonin; Nerve Endings; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Sympathectomy, Chemical

1990
Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides.
    Neuroendocrinology, 1990, Volume: 51, Issue:6

    Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Calcium Chloride; Cations, Divalent; Cerebral Ventricles; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium Chloride; Male; Melatonin; Rats; Rats, Inbred Strains; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin; Thionucleotides

1990
Growth inhibitory and cytotoxic effects of melatonin and its metabolites on human tumour cell lines in vitro.
    British journal of cancer, 1989, Volume: 60, Issue:3

    Topics: 5-Methoxytryptamine; 5,6-Dihydroxytryptamine; Cell Line; Drug Screening Assays, Antitumor; Humans; Melatonin; Serotonin; Tryptamines; Tumor Cells, Cultured

1989
The mass spectrometric analysis of the urinary metabolites of melatonin and its deuterated analogues, confirming their identity as N-acetylserotonin and 6-hydroxymelatonin.
    Biomedical mass spectrometry, 1985, Volume: 12, Issue:7

    Topics: Animals; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Melatonin; Rats; Rats, Inbred Strains; Serotonin

1985
Rapid and simple synthesis for the sulphate esters of 6-hydroxy-melatonin and N-acetyl-serotonin.
    Journal of pineal research, 1988, Volume: 5, Issue:4

    Topics: Melatonin; Serotonin; Sulfates

1988
The isolation, purification, and characterisation of the principal urinary metabolites of melatonin.
    Journal of pineal research, 1987, Volume: 4, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Melatonin; Serotonin; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfates

1987
Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:1

    Topics: Adult; Biotransformation; Deuterium; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Male; Melatonin; Serotonin; Sulfates

1985
Melatonin can be differentially metabolized in the rat to produce N-acetylserotonin in addition to 6-hydroxy-melatonin.
    Endocrinology, 1984, Volume: 114, Issue:5

    Topics: Animals; Chromatography, Thin Layer; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Melatonin; Rats; Rats, Inbred Strains; Serotonin

1984
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
    FEBS letters, 1997, Apr-21, Volume: 407, Issue:1

    Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines

1997
Melatonin receptor pharmacology: toward subtype specificity.
    Biology of the cell, 1997, Volume: 89, Issue:8

    Topics: 3T3 Cells; 5-Methoxytryptamine; Acetylation; Animals; Binding Sites; Binding, Competitive; Clone Cells; Cloning, Molecular; GTP-Binding Proteins; Humans; Ligands; Melanocytes; Melanophores; Melatonin; Methylation; Mice; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serotonin; Species Specificity; Structure-Activity Relationship; Transfection; Tryptamines; Xenopus laevis

1997
Characterization of membrane melatonin receptor in mouse peritoneal macrophages: inhibition of adenylyl cyclase by a pertussis toxin-sensitive G protein.
    Journal of neuroimmunology, 1999, Mar-01, Volume: 95, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Blotting, Western; Colforsin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Iodine Radioisotopes; Kinetics; Macrophages, Peritoneal; Melatonin; Mice; Neuroimmunomodulation; Pertussis Toxin; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin; Signal Transduction; Tryptamines; Virulence Factors, Bordetella

1999
Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules.
    Journal of pineal research, 2000, Volume: 29, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbolines; Carcinogens; Cattle; Chromium; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Indoles; Melatonin; Serotonin

2000
Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP1A2; Enzyme Inhibitors; Fluvoxamine; Humans; Melatonin; Microsomes, Liver; Serotonin; Theophylline

2001
Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kinetics; Kynuramine; Liver; Male; Melatonin; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Serotonin; Spectrometry, Mass, Electrospray Ionization

2008
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:7

    Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Keratin-10; Keratin-14; Keratinocytes; Kinetics; Kynuramine; Melanocytes; Melanoma; Melatonin; Metabolic Networks and Pathways; Serotonin; Skin; Spectrometry, Mass, Electrospray Ionization; Swine

2013
Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.
    Journal of pineal research, 2014, Volume: 57, Issue:1

    Topics: Cell Line; DNA Damage; Humans; Keratinocytes; Kynuramine; Melatonin; Serotonin; Ultraviolet Rays

2014
N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin.
    The journal of physical chemistry. B, 2015, Jul-09, Volume: 119, Issue:27

    Topics: Copper; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Oxidative Stress; Peroxides; Serotonin; Solvents; Water

2015