n-acetylneuraminoyllactose has been researched along with lactose in 167 studies
| Studies (n-acetylneuraminoyllactose) | Trials (n-acetylneuraminoyllactose) | Recent Studies (post-2010) (n-acetylneuraminoyllactose) | Studies (lactose) | Trials (lactose) | Recent Studies (post-2010) (lactose) |
|---|---|---|---|---|---|
| 188 | 3 | 96 | 12,201 | 446 | 3,106 |
| 56 | 2 | 43 | 12,201 | 446 | 3,106 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (13.77) | 18.7374 |
| 1990's | 35 (20.96) | 18.2507 |
| 2000's | 21 (12.57) | 29.6817 |
| 2010's | 66 (39.52) | 24.3611 |
| 2020's | 22 (13.17) | 2.80 |
| Authors | Studies |
|---|---|
| Abou-Issa, H; Srivastava, PN | 1 |
| Meyer, B; Poppe, L; Stuike-Prill, R; van Halbeek, H | 1 |
| Galliker, PK; Glick, GD; Knowles, JR; Toogood, PL | 1 |
| Wright, CS | 1 |
| Air, GM; Lentz, MR | 1 |
| Evans, DG; Evans, DJ; Graham, DY; Moulds, JJ | 1 |
| Barile, MF; Ginsburg, V; Krivan, HC; Olson, LD; Roberts, DD | 1 |
| Sweeley, CC; Usuki, S | 1 |
| Bednarski, MD; Ostroff, G; Simon, ES; Toone, EJ; Whitesides, GM | 1 |
| Bouwstra, JB; Deyl, CM; Vliegenthart, JF | 1 |
| Evans, DG; Evans, DJ; Graham, DY; Smith, KE | 1 |
| Ito, M; Mizu, H; Nagai, Y; Saito, K; Sugiyama, N | 1 |
| Fuse, A; Nakajima, H; Sato, T; Sugita, K | 1 |
| Carlson, DM; Jourdian, GW; Roseman, S | 1 |
| Farooqui, AA; Srivastava, PN | 1 |
| Baruch, D; Breuer, WV; Cabantchik, ZI; Ginsburg, H; Kahane, I | 1 |
| Barenholz, Y; Gatt, S; Gazit, B | 1 |
| Mattingly, SJ; Milligan, TW; Straus, DC | 1 |
| Kuriyama, M; Miyatake, T; Someya, F; Yamada, T | 1 |
| Giles, J; Soslau, G | 1 |
| Hänel, I; Heller, M; Pfützner, H; Sachse, K | 1 |
| Doig, P; Huang, J; Janzon, L; Kostrzynska, M; O'Toole, PW; Trust, TJ | 1 |
| Hanasaki, K; Powell, LD; Varki, A | 1 |
| Hattori, M; Hayashi, H; Horiuchi, R; Hosaka, K; Kojima, I | 1 |
| Barber, EK; Crocker, PR; Freeman, SD; Kelm, S | 1 |
| Fujikura, T; Futatsuya, R; Katoh, T; Kominato, Y; Sakamoto, T; Shimada, I; Shoji, M | 1 |
| Idota, T; Kawakami, H; Murakami, Y; Sugawara, M | 1 |
| Laferrière, CA; Roy, R | 1 |
| Ibric, L; Kim, KS; Luckett, P; Prasadarao, NV; Stins, MF; Wass, CA | 1 |
| Kloetzel, JK; Pereira-Chioccola, VL; Schenkman, S | 1 |
| Air, GM; Janakiraman, MN; Laver, WG; Luo, M; White, CL | 1 |
| Hernández-Jáuregui, P; Montaño, LF; Reyes-Leyva, J; Zenteno, E | 1 |
| Deya, E; Hanagata, G; Hasegawa, A; Kiso, M; Suzuki, T; Suzuki, Y; Xu, G | 1 |
| Bergström, J; Karlsson, KA; Milh, MA; Miller-Podraza, H | 1 |
| Goode, PL; Mobasseri, A; Simon, PM; Zopf, D | 1 |
| Moran, AP; Valkonen, KH; Wadström, T | 1 |
| Bovin, NV; Gambaryan, AS; Lvov, DK; Matrosovich, MN; Piskarev, VE; Robertson, JS; Tuzikov, AB; Yamnikova, SS | 1 |
| Gordon, A; May, JT; Portelli, J | 2 |
| Artursson, E; Hirmo, S; Nilsson, B; Puu, G; Wadström, T | 1 |
| Nakagawa, M; Nakamura, T; Saito, T; Urashima, T | 1 |
| El-Zaimaity, HM; Gilger, MA; Graham, DY; Headon, DR; Malaty, HM; Opekun, AR; Osato, MS; Terry, M | 1 |
| Boddupalli, H; Jacob, GS; Khai Huynh, Q; Shailubhai, K; Yu, HH | 1 |
| Iorio, RM; Wang, Z | 1 |
| Fu, D; Zopf, D | 1 |
| Kobayashi, K; Matsubara, N; Muramatsu, T; Suzuki, T; Suzuki, Y; Tsuchida, A | 1 |
| Crocker, PR; Drickamer, K; Kelm, S; Vinson, M | 1 |
| Razi, N; Varki, A | 1 |
| Baigent, SJ; Bethell, RC; McCauley, JW | 1 |
| Dubois, A; Heman-Ackah, LM; Mysore, JV; Simon, PM; Wigginton, T; Zopf, D | 1 |
| Kok, DJ; Romijn, JC; van der Boom, BG; Verkoelen, CF | 1 |
| Nakanishi, H; Yamagaki, T | 1 |
| Horenstein, BA; Schenkman, S; Yang, J | 1 |
| Eswaramoorthy, S; Swaminathan, S | 1 |
| Crennell, S; Portner, A; Takimoto, T; Taylor, G | 1 |
| Henk, A; Lee, MD; Maier, M; Mizan, S; Stallings, A | 1 |
| Arai, I; Bubb, WA; Nakamura, T; Saito, T; Urashima, T | 1 |
| Albouz-Abo, S; Kiefel, MJ; von Itzstein, M; Wilson, JC | 1 |
| Agnihotri, N; Chaturvedi, G; Ganguly, NK; Tewari, R; Vishwakarma, RA | 1 |
| Guerrini, M; Lay, L; Poletti, L; Rencurosi, A; Russo, G | 1 |
| Higuchi, N; Murakami, Y; Nakamura, H; Oppenheim, FG; Yoshimura, F | 1 |
| Gray, JS; Mulcahy, G; Skerrett, HE; Westbrook, C; Zintl, A | 1 |
| Eskelinen, M; Halonen, T; Punnonen, K; Romppanen, EL; Romppanen, J | 1 |
| CAPUTTO, R; TRUCCO, RE | 1 |
| CAPUTTO, R; CARUBELLI, R; RYAN, LC; TRUCCO, RE | 1 |
| MAYRON, LW; TOKES, ZA | 1 |
| ADA, GL; FRENCH, EL | 1 |
| CARLSON, DM; JDOURDIAN, GW; ROSEMAN, S | 1 |
| CAPUTTO, R; CARUBELLI, R; TAHA, B; TRUCCO, RE | 1 |
| Benie, AJ; Bhunia, A; Jayalakshmi, V; Kelm, S; Peters, T; Rama Krishna, N; Schuster, O | 1 |
| Miyata, M; Nagai, R | 1 |
| Arai, I; Asakuma, S; Fukuda, K; Fukui, Y; Ishikawa, H; Kobayashi, M; Mogoe, T; Saito, T; Uemura, Y; Urashima, T | 1 |
| Akahori, M; Arai, I; Asakuma, S; Kimura, K; Nakamura, T; Sanai, Y; Tsunemi, M; Urashima, T; Watanabe, Y | 1 |
| Fierfort, N; Samain, E | 1 |
| Endo, S; Maeda, T; Morita, M; Terabayashi, T; Ueno, M | 1 |
| Hasegawa, T; Otsuka, A; Sakurai, K | 1 |
| Malicdan, MC; Nishino, I; Noguchi, S | 1 |
| Barile, D; Chu, C; German, JB; Grimm, R; Lebrilla, CB; Marotta, M; Mehra, R | 1 |
| Hirashima, M; Kamitori, S; Nakakita, S; Nakamura, T; Nishi, N; Teraoka, M; Yoshida, H | 1 |
| Kornspan, JD; Rottem, S; Tarshis, M | 1 |
| Cheng, S; Gao, GF; Li, X; Wu, P | 1 |
| Forcella, ME; Fusi, PA; Mazzacuva, P; Monti, E; Mozzi, A; Zampella, G | 1 |
| Casas, J; Contreras, FX; Erkizia, I; Fabriàs, G; Glass, B; Izquierdo-Useros, N; Kräusslich, HG; Lorizate, M; Martinez-Picado, J; Prado, JG; Rodriguez-Plata, MT | 1 |
| Duncan, PI; Sprenger, N | 1 |
| Chen, X; Comstock, SS; Donovan, SM; Hester, SN; Kuhlenschmidt, MS; Kuhlenschmidt, TB; Li, M; Monaco, MH | 1 |
| Borsig, L; Hausmann, M; Hennet, T; Kurakevich, E; Rogler, G | 1 |
| Comstock, SS; Donovan, SM; Hester, SN; Li, M; Wang, M | 1 |
| Arnous, A; Guo, Y; Jers, C; Kirpekar, F; Li, H; Meyer, AS; Mikkelsen, JD | 1 |
| Bovee-Oudenhoven, IM; Feitsma, AL; Schoterman, MH; ten Bruggencate, SJ; van Hoffen, E | 1 |
| Acar, DD; Desmarets, LMB; Nauwynck, HJ; Roukaerts, IDM; Theuns, S | 1 |
| Luo, J; Meyer, AS; Mikkelsen, JD; Morthensen, ST; Nordvang, RT; Pinelo, M; Zeuner, B | 1 |
| Fukui, K; Gromiha, MM; Murugan, V; Parasuraman, P; Selvin, JF; Veluraja, K | 1 |
| Bailey, MT; Berg, BM; Chichlowski, M; Fisher, SE; Galley, JD; Tarr, AJ | 1 |
| Guo, Y; Jers, C; Kirpekar, F; Li, H; Meyer, AS; Mikkelsen, JD | 1 |
| Cattaneo, TM; Curadi, MC; Monti, L; Orlandi, M | 1 |
| Ekman, B; Landberg, E; Wahlberg, J | 1 |
| Connaris, H; Potter, JA; Taylor, GL; Yang, L | 1 |
| Barile, D; de MeloSilva, VL; Lee, H; Liu, Y | 1 |
| Ballmann, MZ; Benkő, M; Berbís, MÁ; Cañada, FJ; Harrach, B; Jiménez-Barbero, J; Joshi, L; Kilcoyne, M; Menéndez, M; Nguyen, TH; Singh, AK; van Raaij, MJ | 1 |
| Alsalmi, W; Alving, CR; Ehrenberg, PK; Gao, G; Jobe, O; Kim, J; Kim, JH; Michael, NL; Peachman, KK; Rao, M; Rao, VB; Thomas, R; Tovanabutra, S; Trinh, HV | 1 |
| Berg, BM; Chichlowski, M; Dasgupta, S; Jacobi, SK; Li, D; Odle, J; Yatsunenko, T; Yu, RK | 1 |
| Imberty, A; Mahal, LK; Pau, W; Pifferi, C; Renaudet, O; Ribeiro, JP; Varrot, A | 1 |
| Agustí, R; Cagnoni, AJ; Cano, ME; de Lederkremer, RM; Kovensky, J; Uhrig, ML | 1 |
| Arabaci, C; Borum, AE; Ekin, IH; Ekin, S; Gurturk, K; Ilhan, Z; Yesilova, A | 1 |
| Bunesova, V; Lacroix, C; Schwab, C | 1 |
| Chen, DDY; Risley, JM | 1 |
| An, SW; Huang, CL; Kohler, JJ; Lim, C; Nischan, N; Oliver, N; Wright, JD; Xie, J; Yoon, J | 1 |
| Fujiwara, Y; Hoshino, Y; Matsubara, T; Miura, Y; Nagao, M; Sato, T | 1 |
| Berg, BM; Chichlowski, M; Dilger, RN; Donovan, SM; Fleming, SA; Labhart, B; Mudd, AT | 1 |
| Cheong, KM; Jang, SH; Kim, DH; Kim, JB; Oh, JS; Pandey, RP; Sohng, JK; Song, J; Woo, J | 1 |
| Berg, BM; Chichlowski, M; Dilger, RN; Donovan, SM; Fleming, SA | 1 |
| Arnold, EA; Chen, L; Driver, AD; Krause, DC; Locklin, J; Sheppard, ES; Williams, CR | 1 |
| Bering, SB; Brandt, AB; Chichlowski, M; Heckmann, AB; Nguyen, DN; Nielsen, DS; Obelitz-Ryom, K; Rendboe, AK; Rudloff, S; Sangild, PT; Thymann, T | 1 |
| Ebara, Y; Kaihatsu, K; Yamabe, M | 1 |
| Brugman, S; Fernandez-Gutierrez, MM; Kleerebezem, M; Perdijk, O; Savelkoul, HFJ; Schuren, FHJ; van Baarlen, P; van den Brink, E; van Neerven, RJJ | 1 |
| Černocká, H; Fojt, L; Ostatná, V; Paleček, E; Trefulka, M | 1 |
| An, SW; Huang, CL; Lim, C; Wright, JD; Xie, J | 1 |
| Chen, Y; Fang, W; Qiao, Z; Troy, FA; Wang, B; Yang, C; Zhang, N; Zhang, P | 1 |
| Hoshino, Y; Matsubara, T; Miura, Y; Nagao, M; Sato, T | 1 |
| Bering, SB; Brunse, A; Eskildsen, SF; Heckmann, AB; Obelitz-Ryom, K; Olesen, JL; Overgaard, SH; Pankratova, S; Ringgaard, S; Rydal, MP; Sangild, PT; Skovgaard, K; Thymann, T; Wang, B | 1 |
| An, HJ; Bae, SJ; Chung, TW; Ha, KT; Jin, BR; Jin, L; Kim, EY; Park, H; Ryu, D | 1 |
| Chapla, DG; Kitov, PI; Kitova, EN; Klassen, JS; Li, Z; Macauley, MS; Moremen, KW; Mozenah, F; Rodrigues, E | 1 |
| Günther, SC; Hennet, T; Khanzhin, N; Maier, JD; Podvalnyy, N; Stertz, S; Vetter, J | 1 |
| Bhatia, S; Cheng, C; Haag, R; Kerkhoff, Y; Nie, C; Oehrl, A; Parshad, B; Stadtmüller, M; Wolff, T | 1 |
| Chleilat, F; Klancic, T; Ma, K; Nettleton, JE; Reimer, RA; Schick, A | 1 |
| Damak, S; Foata, F; Rochat, F; Sprenger, N | 1 |
| Bergonzelli, G; Garcia-Rodenas, CL; Keddani, S; Natividad, JM; Rytz, A | 1 |
| de Haan, N; Pongracz, T; Verhoeven, A; Wuhrer, M | 1 |
| Eom, HY; Hwang, JH; Jang, SI; Kim, L; Lee, JH | 1 |
| Cai, X; Hu, J; Liu, S; Mao, Y; Peng, B; Tian, F; Wang, J; Wang, S; Zhao, Y; Zou, Y | 1 |
| Altmann, F; Helm, J; Hirtler, L | 1 |
| Conze, DB; Derya, SM; Ho, M; Kruger, CL; Lodder, R; Parkot, J; Parschat, K; Schönknecht, YB; Symonds, JM | 1 |
| Adachi, R; Hatano, K; Koyama, T; Matsuoka, K; Matsushita, T | 1 |
| Armand, S; Fort, S; Jeacomine, I; Richard, E; Rivollier, P; Samain, E | 1 |
| Ding, Y; Erney, R; Haselberger, P; Lin, Q; Liu, S; Tian, F; Wang, S | 1 |
| Boddupalli, H; Broschat, KO; Huynh, QK; Jacob, GS; Shailubhai, K; Yu, HH | 1 |
| Bovin, N; Chinarev, A; Egorov, A; Gambaryan, A; Katinger, D; Katinger, H; Mochalova, L; Romanova, J; Tuzikov, A | 1 |
| Bovin, NV; Chinarev, AA; Gambaryan, AS; Karasin, AI; Klimov, AI; Matrosovich, MN; Olsen, CW; Pazynina, GV; Tuzikov, AB | 1 |
| Hatanaka, K; Kato, T; Kawaguchi, A; Nagata, K | 1 |
| Drouillard, S; Kajiwara, H; Mine, T; Samain, E; Yamamoto, T | 1 |
| Chen, W; Lee, RK; Li, J; Liu, X; Qiu, H | 1 |
| Hatanaka, K; Kato, T | 1 |
| Darji, A; Dietrich, U; Panou-Pomonis, E; Sakarellos-Daitsiotis, M; Zabala, JG; Zevgiti, S | 1 |
| Böttcher, S; Champion, E; Dékány, G; Hederos, M; Thiem, J | 1 |
| Choi, YH; Jang, KS; Kim, BG; Kim, DH; Kim, JH; Lee, N; Park, IH; Park, JH | 1 |
| Davis, SR; Holscher, HD; Tappenden, KA | 1 |
| Alexander, D; Bauer, LL; Chow, J; Faber, TA; Fahey, GC; Panasevich, MR; Rossoni Serao, MC; Vester Boler, BM | 1 |
| Cho, A; Hayashi, YK; Malicdan, MC; Mine, T; Nishino, I; Noguchi, S; Nonaka, I; Yamamoto, T; Yonekawa, T | 1 |
| Hemmi, H; Hirabayashi, J; Kuno, A; Unno, S | 1 |
| Austin, S; Bénet, T; De Castro, CA; Hou, Y; Sun, H; Thakkar, SK; Vinyes-Pares, G; Wang, P; Zhang, Y | 1 |
| Buck, R; Ramirez, M; Rueda, R; Santos-Fandila, A; Vazquez, E | 1 |
| Goda, T; Horiguchi, Y; Matsumoto, A; Miyahara, Y; Takeuchi, H; Yamaoka, S | 1 |
| Angulo, J; Bell, A; Chen, X; Horrex, M; Juge, N; Khedri, Z; Lallement, R; Lecointe, K; Monaco, S; Owen, CD; Šuligoj, T; Tailford, LE; Taylor, GL; Tribolo, S; Varki, A; Vaux, L; Walshaw, J; Yu, H | 1 |
| Gao, Y; Gurung, RB; Kim, DH; Kim, L; Lee, AW; Wang, Z | 1 |
| Catassi, C; Coppa, GV; Facinelli, B; Gabrielli, O; Magi, G; Marini, E; Monachesi, C; Santoro, L; Zampini, L | 1 |
| Mukai, T; Nagai, A; Nishiyama, K; Okada, N; Uribayashi, K; Yamamoto, Y | 1 |
| Brugman, S; Perdijk, O; Savelkoul, HFJ; van den Brink, E; van Neerven, RJJ | 1 |
| Barranco, A; Buck, R; Delgado-García, JM; Gruart, A; Martín, MJ; Oliveros, E; Ramírez, M; Rueda, R; Vázquez, E | 1 |
| An, HJ; Chung, TW; Ha, KT; Jin, BR; Kim, EY; Kim, HJ | 1 |
| Alberti, Á; Béni, S; Csernák, O; Rácz, B | 1 |
| Banfield, E; Buck, RH; Fulton, WB; Goehring, KC; Hackam, DJ; Jia, H; Kovler, M; Ladd, MR; Lu, P; Niño, DF; Prindle, T; Sodhi, CP; Wang, S; Werts, AD; Wipf, P; Yamaguchi, Y; Zhou, Q | 2 |
| Eom, HY; Jang, SI; Lee, JH | 1 |
| Eom, HY; Hwang, JH; Jang, SI; Kang, JS; Kim, L; Lee, JH | 1 |
| Jiang, S; Ju, M; Li, K; Lyu, Y; Sun, H; Wang, W; Xu, Y; Zhang, W; Zhao, R; Zheng, C; Zhou, Y | 1 |
| Baek, A; Go, TH; Kang, DR; Kim, JH; Kim, SH; Yong, SY | 1 |
| Heo, KS; Jin, Y; Kim, L; Nguyen, TLL | 1 |
5 review(s) available for n-acetylneuraminoyllactose and lactose
| Article | Year |
|---|---|
[Animal model of distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy and preclinical trial with sugar compounds].
Topics: Administration, Oral; Animals; Disease Models, Animal; Distal Myopathies; Drug Evaluation, Preclinical; Hexosamines; Humans; Inclusion Bodies; Lactose; Mice; Mice, Transgenic; N-Acetylneuraminic Acid; Sialic Acids; Vacuoles | 2010 |
Sialic acid utilization.
Topics: Aged, 80 and over; Animals; Glycoconjugates; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Lactose; Milk, Human; Models, Animal; Oligosaccharides; Sialic Acids | 2012 |
Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides.
Topics: Animals; Breast Feeding; Diet; Dietary Supplements; Gastrointestinal Tract; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Lactose; Milk, Human; Nutritional Requirements; Oligosaccharides; Sialic Acids | 2014 |
Weighted analysis of 2'-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3'-sialyllactose, and 6'-sialyllactose concentrations in human milk.
Topics: Female; Humans; Infant; Lactose; Milk, Human; Oligosaccharides; Trisaccharides | 2022 |
Dynamic Changes in Human Milk Oligosaccharides in Chinese Population: A Systematic Review and Meta-Analysis.
Topics: Breast Feeding; China; Female; Fucose; Humans; Lactation; Lactose; Milk, Human; Oligosaccharides; Sialic Acids | 2021 |
2 trial(s) available for n-acetylneuraminoyllactose and lactose
| Article | Year |
|---|---|
Dietary Sialyllactose Influences Sialic Acid Concentrations in the Prefrontal Cortex and Magnetic Resonance Imaging Measures in Corpus Callosum of Young Pigs.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Corpus Callosum; Diet; Lactose; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Sialic Acids; Swine | 2017 |
Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6'-Sialyllactose in healthy adults.
Topics: Adult; Aged; Humans; Lactose; Middle Aged; Milk, Human; Polysaccharides | 2022 |
160 other study(ies) available for n-acetylneuraminoyllactose and lactose
| Article | Year |
|---|---|
Purification and properties of rabbit spermatozoal acrosomal neuraminidase.
Topics: Acrosome; alpha-Fetoproteins; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrolytes; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Lactose; Male; Mucins; Neuraminidase; Rabbits; Sialic Acids; Spermatozoa | 1977 |
The solution conformation of sialyl-alpha (2----6)-lactose studied by modern NMR techniques and Monte Carlo simulations.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Lactose; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Monte Carlo Method; Sialic Acids | 1992 |
Monovalent sialosides that bind tightly to influenza A virus.
Topics: Binding, Competitive; Bromelains; Hemagglutinins, Viral; Influenza A virus; Lactose; Molecular Structure; Sialic Acids; Structure-Activity Relationship | 1991 |
2.2 A resolution structure analysis of two refined N-acetylneuraminyl-lactose--wheat germ agglutinin isolectin complexes.
Topics: Binding Sites; Electrons; Lactose; Models, Molecular; Protein Conformation; Sialic Acids; Stereoisomerism; Temperature; Water; Wheat Germ Agglutinins; X-Ray Diffraction | 1990 |
Loss of enzyme activity in a site-directed mutant of influenza neuraminidase compared to expressed wild-type protein.
Topics: alpha-Fetoproteins; Cloning, Molecular; DNA; DNA, Viral; Genetic Vectors; Influenza A virus; Lactose; Neuraminidase; Protein Conformation; Recombinant Proteins; Sialic Acids; Simian virus 40; Viral Proteins | 1986 |
N-acetylneuraminyllactose-binding fibrillar hemagglutinin of Campylobacter pylori: a putative colonization factor antigen.
Topics: alpha-Fetoproteins; Antigens, Bacterial; Campylobacter; Erythrocytes; Fimbriae Proteins; Hemagglutinins; Humans; Lactose; Microscopy, Electron; Protein Binding; Sialic Acids | 1988 |
Sialic acid-dependent adhesion of Mycoplasma pneumoniae to purified glycoproteins.
Topics: alpha-Fetoproteins; Animals; Bacterial Adhesion; Binding, Competitive; Carbohydrate Conformation; Chorionic Gonadotropin; Glycoproteins; Glycosylation; Lactose; Laminin; Mice; Mycoplasma pneumoniae; N-Acetylneuraminic Acid; Neuraminidase; Oligosaccharides; Sialic Acids | 1989 |
[Secretary sialidase activity and GM3 ganglioside].
Topics: Cell Cycle; Cells, Cultured; Fibroblasts; G(M3) Ganglioside; Hydrogen-Ion Concentration; Hydrolysis; Lactose; N-Acetylneuraminic Acid; Neuraminidase; Sialic Acids; Substrate Specificity | 1989 |
Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid.
Topics: Clostridium perfringens; Cytidine Monophosphate N-Acetylneuraminic Acid; Cytidine Triphosphate; Hyaluronic Acid; Indicators and Reagents; Lactose; Magnetic Resonance Spectroscopy; N-Acetylneuraminic Acid; Neuraminidase; Oligosaccharides; Sialic Acids; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate Sugars | 1989 |
Purification and kinetic properties of sialidase from Clostridium perfringens.
Topics: Chromatography; Chromatography, High Pressure Liquid; Clostridium perfringens; Electrophoresis, Polyacrylamide Gel; Glycosylation; Kinetics; Lactose; Methanol; Molecular Weight; Neuraminidase; Sialic Acids | 1987 |
Serum antibody responses to the N-acetylneuraminyllactose-binding hemagglutinin of Campylobacter pylori.
Topics: Antibodies, Bacterial; Campylobacter; Campylobacter Infections; Enzyme-Linked Immunosorbent Assay; Hemagglutinins; Humans; Immunoglobulin G; Lactose; Serologic Tests; Sialic Acids | 1989 |
A high-precision selective determination method for free N-acetylneuraminic acid in human serum.
Topics: Adult; Gas Chromatography-Mass Spectrometry; Humans; Lactose; Male; N-Acetylneuraminic Acid; Sialic Acids | 1988 |
The effects of glycolipids and carbohydrates on bilirubin cytotoxicity in vitro.
Topics: Bilirubin; Cells, Cultured; Cerebrosides; Gangliosides; Globosides; Glycosphingolipids; Humans; Lactose; N-Acetylneuraminic Acid; Neuroglia; Sialic Acids; Sulfoglycosphingolipids | 1986 |
The sialic acids. XIV. Synthesis of sialyl-lactose by a sialyltransferase from rat mammary gland.
Topics: Acetates; Amines; Animals; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Cytosine Nucleotides; Decarboxylation; Electrophoresis, Paper; Female; Glucosamine; Glycolates; Glycosides; Hydrogen-Ion Concentration; Kinetics; Lactose; Mammary Glands, Animal; Neuraminic Acids; Nucleotides; Oligosaccharides; Rats; Sialic Acids; Structure-Activity Relationship; Transferases | 1973 |
Studies on neuraminidase activity of the rabbit endometrium.
Topics: alpha-Fetoproteins; Animals; Endometrium; Female; Hydrogen-Ion Concentration; Hydrolysis; Iron; Lactose; Mercury; Mucins; Neuraminidase; Rabbits; Sialic Acids; Superovulation; Temperature; Zinc | 1980 |
Role of internal domains of glycophorin in Plasmodium falciparum invasion of human erythrocytes.
Topics: Acetylglucosamine; alpha-Fetoproteins; Binding Sites; Chemical Phenomena; Chemistry, Physical; Erythrocyte Membrane; Erythrocytes; Glycophorins; Humans; Lactose; Orosomucoid; Ovomucin; Plasmodium falciparum; Sialic Acids; Sialoglycoproteins | 1983 |
Effect of bile salts on the hydrolysis of gangliosides, glycoproteins and neuraminyl-lactose by the neuraminidase of Clostridium perfringens.
Topics: Chemical Phenomena; Chemistry; Clostridium perfringens; Deoxycholic Acid; G(M1) Ganglioside; G(M3) Ganglioside; Gangliosides; Glycoproteins; Hydrolysis; Kinetics; Lactose; Micelles; Neuraminidase; Sialic Acids; Taurodeoxycholic Acid | 1981 |
Purification and partial characterization of neuraminidase from type III group B streptococci.
Topics: Chromatography; Chromatography, Gel; Lactose; Molecular Weight; Neuraminidase; Polysaccharides; Sialic Acids; Streptococcus agalactiae; Substrate Specificity | 1980 |
Radioassay method of neuraminidase towards N-acetylneuraminosyl hexasaccharides.
Topics: Carbohydrate Metabolism, Inborn Errors; Fibroblasts; Humans; Hydrogen-Ion Concentration; Kinetics; Lactose; Lactose Intolerance; Neuraminidase; Oligosaccharides; Sialic Acids | 1982 |
The loss of sialic acid and its prevention in stored human platelets.
Topics: Blood Platelets; Blood Preservation; Humans; In Vitro Techniques; Lactose; Sialic Acids; Temperature; Time Factors | 1982 |
Inhibition of Mycoplasma bovis cytadherence by a monoclonal antibody and various carbohydrate substances.
Topics: Animals; Antibodies, Bacterial; Antibodies, Monoclonal; Bacterial Adhesion; Carbohydrates; Cattle; Cell Line; Dextran Sulfate; Dextrans; Female; Glycophorins; Lactose; Lung; Mastitis, Bovine; Mycoplasma; Mycoplasma Infections; Sialic Acids | 1993 |
The putative neuraminyllactose-binding hemagglutinin HpaA of Helicobacter pylori CCUG 17874 is a lipoprotein.
Topics: Adhesins, Bacterial; Amino Acid Sequence; Base Sequence; Cell Compartmentation; Cloning, Molecular; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Helicobacter pylori; Hemagglutinins; Lactose; Microscopy, Immunoelectron; Molecular Sequence Data; Mutagenesis; Protein Processing, Post-Translational; Sequence Analysis, DNA; Sialic Acids; Species Specificity | 1995 |
Binding of human plasma sialoglycoproteins by the B cell-specific lectin CD22. Selective recognition of immunoglobulin M and haptoglobin.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Carbohydrate Sequence; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chromatography, Affinity; Endothelium, Vascular; Haptoglobins; Humans; Immunoglobulin M; Kinetics; Lactose; Lectins; Ligands; Molecular Sequence Data; Sialic Acid Binding Ig-like Lectin 2; Sialic Acids; Sialoglycoproteins; Substrate Specificity; Tumor Necrosis Factor-alpha; Umbilical Veins | 1995 |
Sialyllactose-mediated cell interaction during granulosa cell differentiation. Identification of its binding proteins.
Topics: Animals; Blotting, Western; Calcium; Carbohydrate Sequence; Cell Communication; Cell Differentiation; Cells, Cultured; Female; G(M3) Ganglioside; Granulosa Cells; Iodine Radioisotopes; Lactose; Manganese; Molecular Sequence Data; Protein Binding; Rats; Rats, Wistar; Serum Albumin; Sialic Acids | 1995 |
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carbohydrate Sequence; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Chlorocebus aethiops; DNA, Complementary; Erythrocytes; Hematopoietic Stem Cells; Humans; Lactose; Membrane Glycoproteins; Molecular Sequence Data; Multigene Family; N-Acetylneuraminic Acid; Neoplastic Stem Cells; Neuraminidase; Receptors, Immunologic; Recombinant Proteins; Sequence Homology; Sialic Acid Binding Ig-like Lectin 1; Sialic Acid Binding Ig-like Lectin 3; Sialic Acids; Transfection; Tumor Cells, Cultured | 1995 |
Elevation of ratio of urinary N-acetylneuraminlactose to free sialic acid in some advanced cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Female; Humans; Lactose; Male; Middle Aged; N-Acetylneuraminic Acid; Sialic Acids; Sialyltransferases; Stomach Neoplasms | 1995 |
Inhibition of cholera toxin by human milk fractions and sialyllactose.
Topics: Animals; Binding, Competitive; Body Fluids; Cholera Toxin; G(M1) Ganglioside; Humans; In Vitro Techniques; Intestinal Mucosa; Intestines; Lactose; Male; Milk, Human; Oligosaccharides; Rabbits; Sialic Acids | 1995 |
Isolation, modification, and conjugation of sialyl alpha(2-->3)-lactose.
Topics: Carbohydrate Sequence; Glycoproteins; Lactose; Molecular Sequence Data; Serum Albumin, Bovine; Sialic Acids | 1994 |
Binding characteristics of S fimbriated Escherichia coli to isolated brain microvascular endothelial cells.
Topics: Animals; Bacterial Adhesion; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Escherichia coli; Fimbriae, Bacterial; Humans; Lactose; Mutation; Sialic Acids | 1994 |
Sera from chronic Chagasic patients and rodents infected with Trypanosoma cruzi inhibit trans-sialidase by recognizing its amino-terminal and catalytic domain.
Topics: Amino Acid Sequence; Animals; Antibodies, Protozoan; Chagas Disease; Erythrocytes; Glycoproteins; Humans; Immunoglobulin G; Lactose; Mice; Molecular Sequence Data; Neuraminidase; Papain; Peptide Fragments; Rodentia; Sialic Acids; Trypanosoma cruzi | 1994 |
Structure of influenza virus neuraminidase B/Lee/40 complexed with sialic acid and a dehydro analog at 1.8-A resolution: implications for the catalytic mechanism.
Topics: Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Influenza B virus; Lactose; Macromolecular Substances; Models, Molecular; Molecular Structure; N-Acetylneuraminic Acid; Neuraminidase; Protein Structure, Secondary; Sialic Acids | 1994 |
The porcine paramyxovirus LPM specifically recognizes sialyl (alpha 2,3) lactose-containing structures.
Topics: Agglutination Tests; Animals; Carbohydrate Sequence; Giant Cells; Humans; Lactose; Molecular Sequence Data; Paramyxoviridae; Receptors, Virus; Sialic Acids; Swine; Vero Cells | 1993 |
Drift of the sialyl-linkage specific recognition of the sialidase of influenza B virus isolates.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Chick Embryo; Gangliosides; Influenza B virus; Lactose; Molecular Sequence Data; Neuraminidase; Sialic Acids; Substrate Specificity | 1993 |
Recognition of glycoconjugates by Helicobacter pylori: an apparently high-affinity binding of human polyglycosylceramides, a second sialic acid-based specificity.
Topics: alpha-Fetoproteins; Binding Sites; Carbohydrate Sequence; Chromatography, Thin Layer; Erythrocyte Membrane; Glycoconjugates; Glycolipids; Glycosphingolipids; Helicobacter pylori; Humans; Lactose; Membrane Glycoproteins; Molecular Sequence Data; N-Acetylneuraminic Acid; Sensitivity and Specificity; Sialic Acids | 1996 |
Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.
Topics: Adrenal Gland Neoplasms; Animals; Bacterial Adhesion; Carcinoma; Epithelium; Gangliosides; Gastrointestinal Neoplasms; Glycoproteins; Helicobacter pylori; Humans; Lactose; Mice; Neuraminidase; Sialic Acids; Sulfates; Tumor Cells, Cultured | 1997 |
Identification of the N-acetylneuraminyllactose-specific laminin-binding protein of Helicobacter pylori.
Topics: Adhesins, Bacterial; Blotting, Western; Carrier Proteins; Glycosylation; Helicobacter pylori; Hemagglutination; Lactose; Laminin; Receptors, Laminin; Sialic Acids | 1997 |
Specification of receptor-binding phenotypes of influenza virus isolates from different hosts using synthetic sialylglycopolymers: non-egg-adapted human H1 and H3 influenza A and influenza B viruses share a common high binding affinity for 6'-sialyl(N-ace
Topics: Amino Sugars; Animals; Cell Line; Chick Embryo; Dogs; Glycoconjugates; Humans; Influenza A virus; Influenza B virus; Lactose; Phenotype; Receptors, Virus; Sialic Acids | 1997 |
Effect of human milk sialyllactose on cytomegalovirus.
Topics: Cells, Cultured; Cytomegalovirus; Humans; Lactose; Milk, Human; Sialic Acids; Viral Plaque Assay; Virus Activation | 1998 |
Characterization of Helicobacter pylori interactions with sialylglycoconjugates using a resonant mirror biosensor.
Topics: Biosensing Techniques; Helicobacter pylori; Lactose; Membrane Proteins; Protein Binding; Sialic Acids | 1998 |
Sialyllactose occurs as free lactones in ovine colostrum.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Colostrum; Female; Lactones; Lactose; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oligosaccharides; Sheep; Sialic Acids | 1998 |
Effect of compounds with antibacterial activities in human milk on respiratory syncytial virus and cytomegalovirus in vitro.
Topics: Animals; Cell Line; Chondroitin Sulfates; Cytomegalovirus; Dermatan Sulfate; Gangliosides; Humans; Lactoferrin; Lactose; Milk, Human; Respiratory Syncytial Viruses; Semliki forest virus; Sialic Acids | 1998 |
Novel therapies for Helicobacter pylori infection.
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Animals; Anti-Ulcer Agents; Breath Tests; Cattle; Colostrum; Female; Helicobacter Infections; Helicobacter pylori; Humans; Immunoglobulin G; Lactoferrin; Lactose; Male; Middle Aged; Recombinant Proteins; Sialic Acids; Treatment Outcome; Urea | 1999 |
Purification and characterization of a lymph node sulfotransferase responsible for 6-O-sulfation of the galactose residues in 2'-fucosyllactose and other sialyl LewisX-related sugars.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Chromatography, Thin Layer; Galactose; Glycoproteins; Hydrogen-Ion Concentration; Kinetics; Lactose; Lectins; Lymph Nodes; Microsomes; Molecular Sequence Data; Molecular Weight; Oligosaccharides; Phosphoadenosine Phosphosulfate; Photoaffinity Labels; Sialic Acids; Substrate Specificity; Sulfates; Sulfotransferases; Swine; Trisaccharides | 1999 |
Amino acid substitutions in a conserved region in the stalk of the Newcastle disease virus HN glycoprotein spike impair its neuraminidase activity in the globular domain.
Topics: Adsorption; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Cell Line; Conserved Sequence; Epitopes; Erythrocytes; Guinea Pigs; HN Protein; Humans; Lactose; Leucine Zippers; Molecular Sequence Data; Neuraminidase; Newcastle disease virus; Protein Conformation; Sialic Acids; Transfection | 1999 |
Analysis of sialyllactoses in blood and urine by high-performance liquid chromatography.
Topics: Antipyrine; Carbohydrates; Chromatography, High Pressure Liquid; Edaravone; Free Radical Scavengers; Humans; Lactose; Oligosaccharides; Reference Standards; Sialic Acids; Temperature; Time Factors | 1999 |
Simple synthesis of sialyllactose-carrying polystyrene and its binding with influenza virus.
Topics: Animals; Antiviral Agents; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Dogs; Glycoconjugates; Hemagglutinin Glycoproteins, Influenza Virus; Lactose; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Orthomyxoviridae; Polystyrenes; Sialic Acids | 1998 |
Molecular analysis of sialoside binding to sialoadhesin by NMR and site-directed mutagenesis.
Topics: Binding Sites; Humans; Lactose; Ligands; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mutagenesis, Site-Directed; Receptors, Immunologic; Sialic Acid Binding Ig-like Lectin 1; Sialic Acids | 1999 |
Cryptic sialic acid binding lectins on human blood leukocytes can be unmasked by sialidase treatment or cellular activation.
Topics: Binding Sites; Biotinylation; Hematologic Neoplasms; Humans; Ionomycin; Ionophores; Lactose; Lectins; Leukocytes; Lymphocyte Activation; N-Acetylneuraminic Acid; Neuraminidase; Neutrophil Activation; Sialic Acids; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Genetic analysis reveals that both haemagglutinin and neuraminidase determine the sensitivity of naturally occurring avian influenza viruses to zanamivir in vitro.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Cells, Cultured; Chick Embryo; Chickens; Dogs; Erythrocytes; Genes, Viral; Glycosylation; Guanidines; Hemagglutination, Viral; Hemagglutinins, Viral; Influenza A virus; Inhibitory Concentration 50; Lactose; Molecular Sequence Data; Mutation; Neuraminidase; Pyrans; Reassortant Viruses; Sialic Acids; Substrate Specificity; Virus Replication; Zanamivir | 1999 |
Treatment of Helicobacter pylori infection in rhesus monkeys using a novel antiadhesion compound.
Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Disease Models, Animal; Drug Therapy, Combination; Genotype; Helicobacter Infections; Helicobacter pylori; Humans; Lactose; Liver Function Tests; Macaca mulatta; Organometallic Compounds; Proton Pump Inhibitors; Salicylates; Sialic Acids | 1999 |
Sialic acid and crystal binding.
Topics: Animals; Binding, Competitive; Calcium Oxalate; Cell Line; Crystallization; Dogs; Kidney; Lactose; Lectins; N-Acetylneuraminic Acid; Neuraminidase; Sialic Acids | 2000 |
A new technique distinguishing alpha2-3 sialyl linkage from alpha2-6 linkage in sialyllactoses and sialyl-N-acetyllactosamines by post-source decay fragmentation method of MALDI-TOF mass spectrometry.
Topics: Amino Sugars; Carbohydrate Sequence; Lactose; Molecular Sequence Data; Sialic Acids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1999 |
Primary 13C and beta-secondary 2H KIEs for trans-sialidase. A snapshot of nucleophilic participation during catalysis.
Topics: Animals; Antigens, Protozoan; Carbohydrate Sequence; Carbon Isotopes; Catalysis; Deuterium; Gangliosides; Glycoproteins; Kinetics; Lactose; Molecular Sequence Data; Neuraminidase; Rats; Sialic Acids; Sialyl Lewis X Antigen; Substrate Specificity; Trypanosoma cruzi | 2000 |
Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.
Topics: Amino Acid Sequence; Binding Sites; Botulinum Toxins; Botulinum Toxins, Type A; Catalytic Domain; Clostridium botulinum; Crystallography, X-Ray; Gangliosides; Lactose; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cell Surface; Sequence Alignment; Sialic Acids | 2000 |
Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; HN Protein; Hydrogen-Ion Concentration; Hydrolysis; Lactose; Ligands; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutation; N-Acetylneuraminic Acid; Newcastle disease virus; Protein Structure, Quaternary; Receptors, Virus; Sequence Alignment; Sialic Acids; Structure-Activity Relationship | 2000 |
Cloning and characterization of sialidases with 2-6' and 2-3' sialyl lactose specificity from Pasteurella multocida.
Topics: Amino Acid Sequence; Cloning, Molecular; Escherichia coli; Hydrogen-Ion Concentration; Lactose; Molecular Sequence Data; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Pasteurella multocida; Sequence Alignment; Sequence Analysis, DNA; Sialic Acids; Substrate Specificity | 2000 |
An NMR study of the lactonization of alpha-N-acetylneuraminyl-(2 --> 3)-lactose.
Topics: Acetic Acid; Animals; Cattle; Chromatography, Thin Layer; Colostrum; Female; Lactones; Lactose; Magnetic Resonance Spectroscopy; Oligosaccharides; Sialic Acids; Spectrometry, Mass, Fast Atom Bombardment; Temperature | 2000 |
Preliminary 1H NMR investigation of sialic acid transfer by the trans-sialidase from Trypanosoma cruzi.
Topics: Amino Sugars; Animals; Chagas Disease; Glycoproteins; Lactose; N-Acetylneuraminic Acid; Neuraminidase; Nuclear Magnetic Resonance, Biomolecular; Protons; Sialic Acids; Sialyltransferases; Trypanosoma cruzi | 2000 |
Inhibition of Helicobacter pylori adherence by a peptide derived from neuraminyl lactose binding adhesin.
Topics: Animals; Bacterial Adhesion; Cells, Cultured; Epithelial Cells; Helicobacter pylori; Humans; Lactose; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Parietal Cells, Gastric; Peptide Fragments; Rabbits; Sialic Acids | 2001 |
Human milk oligosaccharides: an enzymatic protection step simplifies the synthesis of 3'- and 6'-O-sialyllactose and their analogues.
Topics: Acylation; Candida; Carbohydrate Sequence; Fungal Proteins; Humans; Lactose; Lipase; Milk, Human; Molecular Conformation; Molecular Sequence Data; Oligosaccharides | 2002 |
Bacteroides forsythus hemagglutinin is inhibited by N-acetylneuraminyllactose.
Topics: Adhesins, Bacterial; Antibodies; Arginine; Bacteroides; Cell Wall; Helicobacter pylori; Hemagglutination; Hemagglutinins; Hot Temperature; Humans; Lactose; Lysine; Sialic Acids; Trypsin | 2002 |
Chymotrypsin and neuraminidase treatment inhibits host cell invasion by Babesia divergens (Phylum Apicomplexa).
Topics: Animals; Babesia; Babesiosis; Cattle; Chymotrypsin; Erythrocytes; Horses; Humans; Lactose; Neuraminidase; Sheep; Sialic Acids | 2002 |
Reference values of serum total sialic acid for healthy adult subjects and comparison of two different calibrators for quantitation of total sialic acid in high performance anion-exchange chromatography with pulsed amperometric detection.
Topics: Anion Exchange Resins; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrolysis; Lactose; N-Acetylneuraminic Acid; Reference Standards; Reference Values; Reproducibility of Results; Sialic Acids | 2003 |
Neuramin-lactose, a new compound isolated from the mammary gland of rats.
Topics: Animals; Breast; Humans; Lactose; Mammary Glands, Human; Rats; Sialic Acids | 1954 |
Neuramin-lactose sulfate, a new compound isolated from the mammary gland of rats.
Topics: Animals; Breast; Humans; Ions; Lactose; Mammary Glands, Human; Neuraminic Acids; Rats; Sialic Acids; Sulfates | 1961 |
Preparation of neuramin-lactose from bovine colostrum.
Topics: Animals; Cattle; Clostridium; Colostrum; Female; Lactose; Neuraminic Acids; Pregnancy; Sialic Acids | 1960 |
Stimulation of the production of neuraminidase in Vibrio cholerae cultures by N-acetylneuraminic acid and sialyl-lactose.
Topics: Glycoside Hydrolases; Lactose; N-Acetylneuraminic Acid; Neuraminic Acids; Neuraminidase; Sialic Acids; Vibrio; Vibrio cholerae | 1959 |
The enzymatic synthesis of sialyl-lactose.
Topics: Lactose; Sialic Acids | 1963 |
INCORPORATION OF (14C)GLUCOSE INTO LACTOSE AND OF (14C)GLUCOSE INTO LACTOSE AND NEURAMIN-LACTOSE BY RAT MAMMARY GLANDS.
Topics: Animals; Carbohydrate Metabolism; Carbon Isotopes; Chromatography; Female; Galactose; Glucose; Humans; Lactose; Mammary Glands, Animal; Mammary Glands, Human; Neuraminic Acids; Pregnancy; Pregnancy, Animal; Rats; Research; Sialic Acids | 1964 |
Saturation transfer difference NMR and computational modeling of a sialoadhesin-sialyl lactose complex.
Topics: Carbohydrate Sequence; Computer Simulation; Lactose; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Binding; Receptors, Immunologic; Sialic Acid Binding Ig-like Lectin 1; Sialic Acids | 2004 |
Gliding motility of Mycoplasma mobile can occur by repeated binding to N-acetylneuraminyllactose (sialyllactose) fixed on solid surfaces.
Topics: Bacterial Adhesion; Glass; Lactose; Movement; Mycoplasma; Sialic Acids | 2006 |
Chemical characterization of the oligosaccharides in Bryde's whale (Balaenoptera edeni) and Sei whale (Balaenoptera borealis lesson) milk.
Topics: Animals; Balaenoptera; Bottle-Nosed Dolphin; Carbohydrate Sequence; Colostrum; Female; Lactose; Magnetic Resonance Spectroscopy; Milk; Molecular Sequence Data; Oligosaccharides; Sialic Acids; Species Specificity | 2007 |
Sialyl oligosaccharides of human colostrum: changes in concentration during the first three days of lactation.
Topics: Adaptation, Physiological; Colostrum; Female; Humans; Lactation; Lactose; Milk, Human; Oligosaccharides; Pregnancy; Time Factors | 2007 |
Genetic engineering of Escherichia coli for the economical production of sialylated oligosaccharides.
Topics: Acetylglucosamine; Carbohydrate Epimerases; Cytidine Monophosphate N-Acetylneuraminic Acid; Escherichia coli; Fructose-Bisphosphate Aldolase; Gene Deletion; Genetic Enhancement; Industrial Microbiology; Lactose; Mutagenesis, Insertional; N-Acylneuraminate Cytidylyltransferase; Neisseria meningitidis; Oligosaccharides; Oxo-Acid-Lyases; Phosphotransferases (Alcohol Group Acceptor); Sialic Acids; Sialyltransferases; Transformation, Bacterial | 2008 |
Fluorescent labeling of a carboxyl group of sialic acid for MALDI-MS analysis of sialyloligosaccharides and ganglioside.
Topics: Aminopyridines; Chromatography, High Pressure Liquid; Ethylamines; Fluorescence; Fluorescent Dyes; G(M3) Ganglioside; Gangliosides; Lactose; N-Acetylneuraminic Acid; Oligosaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Ferrocenes with two carbohydrate appendages at the upper and lower rings are useful for investigating carbohydrate-carbohydrate interactions.
Topics: Carbohydrates; Cations; Circular Dichroism; Ferrous Compounds; Glycosides; Glycosylation; Lactose; Maltose; Metallocenes; Models, Molecular; Sialic Acids | 2009 |
Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Colostrum; Female; Lactation; Lactose; Mass Spectrometry; Microfluidic Analytical Techniques; Oligosaccharides; Sialic Acids | 2010 |
X-ray structures of human galectin-9 C-terminal domain in complexes with a biantennary oligosaccharide and sialyllactose.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Galectins; Humans; Lactose; Molecular Sequence Data; Oligosaccharides; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sialic Acids | 2010 |
Adhesion and biofilm formation of Mycoplasma pneumoniae on an abiotic surface.
Topics: Adhesins, Bacterial; Bacterial Adhesion; Biofilms; Culture Media; Glycoproteins; Lactose; Mycoplasma pneumoniae; N-Acetylneuraminic Acid; Sialic Acids | 2011 |
Carbohydrate-functionalized chitosan fiber for influenza virus capture.
Topics: Animals; Antiviral Agents; Chitosan; Erythrocytes; Glycosylation; Guinea Pigs; Hemagglutination Inhibition Tests; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Lactose; Orthomyxoviridae; Protein Binding; Sialic Acids; Surface Plasmon Resonance; Virus Attachment | 2011 |
Molecular insight into substrate recognition by human cytosolic sialidase NEU2.
Topics: Catalytic Domain; Computer Simulation; Crystallography, X-Ray; Cytosol; Enzyme Activation; Enzyme Assays; Escherichia coli; Galactose; Humans; Hymecromone; Influenza A Virus, H1N1 Subtype; Lactose; Models, Molecular; Mutagenesis, Site-Directed; Neuraminidase; Protein Binding; Sialic Acids; Substrate Specificity | 2012 |
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Cells, Cultured; Coculture Techniques; Dendritic Cells; Gangliosides; HIV-1; Host-Pathogen Interactions; Humans; Lactose; Liposomes; Membrane Lipids; Molecular Sequence Data; Sialic Acids; Virus Attachment; Virus Internalization | 2012 |
Human milk oligosaccharides inhibit rotavirus infectivity in vitro and in acutely infected piglets.
Topics: Acute Disease; Animals; Diet; Dietary Carbohydrates; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Lactose; Milk, Human; N-Acetylneuraminic Acid; Oligosaccharides; RNA, Messenger; Rotavirus; Rotavirus Infections; Species Specificity; Swine; Viral Nonstructural Proteins; Virus Attachment; Virus Replication | 2013 |
Milk oligosaccharide sialyl(α2,3)lactose activates intestinal CD11c+ cells through TLR4.
Topics: Animals; Animals, Newborn; Bacteria; beta-Galactoside alpha-2,3-Sialyltransferase; CD11c Antigen; Cells, Cultured; Colitis; Cytokines; Dendritic Cells; Female; Flow Cytometry; Gastrointestinal Tract; Gene Expression; Immunity, Mucosal; Interleukin-10; Intestinal Mucosa; Intestines; Lactation; Lactose; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Milk; Reverse Transcriptase Polymerase Chain Reaction; Sialic Acids; Sialyltransferases; Toll-Like Receptor 4 | 2013 |
Select human milk oligosaccharides directly modulate peripheral blood mononuclear cells isolated from 10-d-old pigs.
Topics: Animals; Animals, Newborn; Animals, Suckling; Bottle Feeding; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cytokines; Diet; Humans; Immunologic Factors; Lactose; Leukocytes, Mononuclear; Lymphocyte Activation; Milk, Human; Oligosaccharides; Random Allocation; Sus scrofa; Trisaccharides | 2014 |
A Pasteurella multocida sialyltransferase displaying dual trans-sialidase activities for production of 3'-sialyl and 6'-sialyl glycans.
Topics: Bacterial Proteins; Glycoproteins; Humans; Hydrogen-Ion Concentration; Lactose; Milk Proteins; N-Acetylneuraminic Acid; Neuraminidase; Oligosaccharides; Pasteurella multocida; Recombinant Proteins; Sialyltransferases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Whey Proteins | 2014 |
Role of sialic acids in feline enteric coronavirus infections.
Topics: Animals; Cat Diseases; Cats; Cell Line; Coronavirus Infections; Coronavirus, Feline; Epithelial Cells; Feline Infectious Peritonitis; Fetuins; Gastric Mucins; Intestinal Mucosa; Lactoferrin; Lactose; Neuraminidase; Receptors, Virus; Sialic Acids; Virus Attachment | 2014 |
An integrated membrane system for the biocatalytic production of 3'-sialyllactose from dairy by-products.
Topics: Animals; Caseins; Catalysis; Cellulose; Chromatography, Ion Exchange; Glycopeptides; Lactose; Membranes, Artificial; Milk; Molecular Structure; Neuraminidase; Oligosaccharides; Ultrafiltration | 2014 |
Theoretical investigation on the glycan-binding specificity of Agrocybe cylindracea galectin using molecular modeling and molecular dynamics simulation studies.
Topics: Agrocybe; Galectins; Hydrogen Bonding; Lactose; Molecular Dynamics Simulation; Mutation; Polysaccharides; Protein Binding; Sialic Acids | 2015 |
The prebiotics 3'Sialyllactose and 6'Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut-brain axis.
Topics: Animals; Anxiety; Body Mass Index; Brain; Cell Proliferation; Corticosterone; Doublecortin Protein; Gastrointestinal Microbiome; Interleukin-6; Lactose; Male; Mice; Mice, Inbred C57BL; Neurons; Oligosaccharides; Spleen; Stress, Psychological | 2015 |
Modulating the regioselectivity of a Pasteurella multocida sialyltransferase for biocatalytic production of 3'- and 6'-sialyllactose.
Topics: Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Glycoproteins; Kinetics; Lactose; Models, Molecular; Mutagenesis, Site-Directed; Neuraminidase; Oligosaccharides; Pasteurella multocida; Protein Engineering; Recombinant Proteins; Sialyltransferases; Structural Homology, Protein | 2015 |
Capillary electrophoresis of sialylated oligosaccharides in milk from different species.
Topics: Animals; Cattle; Electrophoresis, Capillary; Equidae; Female; Humans; Lactose; Milk; Milk, Human; Oligosaccharides; Species Specificity | 2015 |
Urine oligosaccharide pattern in patients with hyperprolactinaemia.
Topics: Adult; Aged; Anions; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Female; Healthy Volunteers; Humans; Hyperprolactinemia; Lactose; Male; Middle Aged; Oligosaccharides; Pregnancy; Pregnancy Trimester, Third; Prolactin; Sialic Acids; Thyroid Hormones; Young Adult | 2015 |
Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor.
Topics: Bacterial Proteins; Binding Sites; Lactose; Models, Molecular; Neuraminidase; Protein Binding; Protein Folding; Protein Structure, Tertiary; Sialic Acids; Streptococcus pneumoniae; Virulence Factors | 2015 |
Short communication: Quantification of carbohydrates in whey permeate products using high-performance anion-exchange chromatography with pulsed amperometric detection.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Colostrum; Dietary Carbohydrates; Lactose; Limit of Detection; Milk; Oligosaccharides; Reproducibility of Results; Whey | 2015 |
Structure and Sialyllactose Binding of the Carboxy-Terminal Head Domain of the Fibre from a Siadenovirus, Turkey Adenovirus 3.
Topics: Amino Acid Sequence; Binding Sites; Calorimetry; Carbohydrate Conformation; Carbohydrate Sequence; Crystallography, X-Ray; Lactose; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Polysaccharides; Protein Binding; Protein Structure, Tertiary; Siadenovirus; Sialic Acids; Thermodynamics; Viral Proteins; Virulence | 2015 |
Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 region.
Topics: Capsid Proteins; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; HIV-1; Humans; Lactose; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; N-Acetylneuraminic Acid; Protein Multimerization; Receptors, Virus; Sialic Acid Binding Ig-like Lectin 1; Sialic Acids; Viral Envelope Proteins; Virus Internalization; Virus Replication | 2016 |
Dietary Isomers of Sialyllactose Increase Ganglioside Sialic Acid Concentrations in the Corpus Callosum and Cerebellum and Modulate the Colonic Microbiota of Formula-Fed Piglets.
Topics: Animals; Bacteria; Brain; Cerebellum; Colon; Corpus Callosum; Diet; Dietary Supplements; Gangliosides; Gastrointestinal Microbiome; Infant Formula; Isomerism; Lactose; Milk, Human; Oligosaccharides; Sialic Acids; Swine | 2016 |
Characterization of a high-affinity sialic acid-specific CBM40 from Clostridium perfringens and engineering of a divalent form.
Topics: Bacterial Proteins; Binding Sites; Catalytic Domain; Clostridium perfringens; Crystallography, X-Ray; Kinetics; Lactose; N-Acetylneuraminic Acid; Peptides; Polysaccharides; Protein Binding; Protein Conformation; Receptors, Cell Surface; Sialic Acids; Substrate Specificity | 2016 |
Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography.
Topics: Chromatography, High Pressure Liquid; Glycoproteins; Lactose; Neuraminidase; Protozoan Proteins; Sialic Acids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiogalactosides; Trypanosoma cruzi | 2016 |
Detection and comparison of neuraminidase activities in human and bovine group B streptococci.
Topics: Animals; Cattle; Colorimetry; Humans; Lactose; N-Acetylneuraminic Acid; Neuraminidase; Serotyping; Sialic Acids; Streptococcal Infections; Streptococcus agalactiae | 2016 |
Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense.
Topics: alpha-L-Fucosidase; Base Sequence; beta-Galactosidase; Bifidobacterium; Bifidobacterium longum; DNA, Bacterial; Fatty Acids, Volatile; Feces; Fucose; Genome, Bacterial; Humans; Infant; Intestines; Lactose; Metabolic Networks and Pathways; Milk, Human; Oligosaccharides; Propylene Glycol; RNA, Ribosomal, 16S; Sialic Acids; Trisaccharides | 2016 |
Improved sensitivity by post-column chemical environment modification of CE-ESI-MS using a flow-through microvial interface.
Topics: Electrolytes; Electrophoresis, Capillary; Lactose; N-Acetylneuraminic Acid; Neuraminic Acids; Oligosaccharides; Sensitivity and Specificity; Sialic Acids; Spectrometry, Mass, Electrospray Ionization | 2017 |
Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbohydrate Conformation; Cardiomegaly; Computer Simulation; Gangliosides; Gene Expression Regulation; Glucuronidase; HEK293 Cells; Humans; Klotho Proteins; Lactose; Membrane Microdomains; Mice; Models, Molecular; Phosphatidylinositol 3-Kinases; Protein Conformation; Sialic Acids; Signal Transduction | 2017 |
Design of Glycopolymers Carrying Sialyl Oligosaccharides for Controlling the Interaction with the Influenza Virus.
Topics: Animals; Cell Line; Click Chemistry; Dogs; Lactose; Madin Darby Canine Kidney Cells; Oligosaccharides; Orthomyxoviridae; Polymerization; Polymers; Sugars | 2017 |
Broad-spectrum neutralization of avian influenza viruses by sialylated human milk oligosaccharides: in vivo assessment of 3'-sialyllactose against H9N2 in chickens.
Topics: Animals; Antiviral Agents; Chickens; Dogs; Humans; Influenza A Virus, H9N2 Subtype; Lactose; Madin Darby Canine Kidney Cells; Milk, Human; Models, Animal; Oligosaccharides; Republic of Korea | 2018 |
Dietary Sialyllactose Does Not Influence Measures of Recognition Memory or Diurnal Activity in the Young Pig.
Topics: Activity Cycles; Age Factors; Animal Feed; Animals; Behavior, Animal; Circadian Rhythm; Diet; Lactose; Locomotion; Male; Recognition, Psychology; Sialic Acids; Sus scrofa; Time Factors | 2018 |
Sialylated Receptor Setting Influences Mycoplasma pneumoniae Attachment and Gliding Motility.
Topics: Adhesins, Bacterial; Glycoproteins; Humans; Lactose; Movement; Mycoplasma pneumoniae; N-Acetylneuraminic Acid; Pneumonia, Mycoplasma; Sialic Acids | 2018 |
Bovine Milk Oligosaccharides with Sialyllactose for Preterm Piglets.
Topics: Animals; Animals, Newborn; Cattle; Dietary Supplements; Female; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Immunity; Infant, Newborn; Infant, Premature; Lactose; Male; Milk; Oligosaccharides; Sialic Acids; Swine; Whey | 2018 |
Binding inhibition of various influenza viruses by sialyllactose-modified trimer DNAs.
Topics: Antiviral Agents; DNA; Humans; Influenza A virus; Lactose; Sialic Acids; Virus Attachment | 2019 |
Sialyllactose and Galactooligosaccharides Promote Epithelial Barrier Functioning and Distinctly Modulate Microbiota Composition and Short Chain Fatty Acid Production
Topics: Alkaline Phosphatase; Bacteroides; Bifidobacterium; Caco-2 Cells; Cell Cycle; Cell Differentiation; Cell Proliferation; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Infant; Intestinal Mucosa; Lactose; Milk, Human; Oligosaccharides; Sialic Acids; Tight Junctions; Transcriptome | 2019 |
Distinguishing the glycan isomers 2,3-sialyllactose and 2,6-sialyllactose by voltammetry after modification with osmium(VI) complexes.
Topics: Coordination Complexes; Electrochemical Techniques; Humans; Lactose; Osmium; Sialic Acids; Stereoisomerism | 2019 |
Soluble klotho regulates TRPC6 calcium signaling
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Signaling; Cell Line; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glucuronidase; HEK293 Cells; Humans; Klotho Proteins; Lactose; Membrane Microdomains; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Interaction Domains and Motifs; Rats; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Sialic Acids; Solubility; TRPC6 Cation Channel | 2019 |
Molecular Mechanisms Underlying How Sialyllactose Intervention Promotes Intestinal Maturity by Upregulating GDNF Through a CREB-Dependent Pathway in Neonatal Piglets.
Topics: Animals; Animals, Newborn; Cyclic AMP Response Element-Binding Protein; Diarrhea; Enteric Nervous System; Glial Cell Line-Derived Neurotrophic Factor; Intestine, Small; Lactose; Male; Random Allocation; Sialic Acids; Signal Transduction; Sus scrofa; Swine; Up-Regulation | 2019 |
Synthesis of Various Glycopolymers Bearing Sialyllactose and the Effect of Their Molecular Mobility on Interaction with the Influenza Virus.
Topics: Humans; Influenza, Human; Lactose; Ligands; Nanomedicine; Oligosaccharides; Orthomyxoviridae; Polymers; Polysaccharides; Sialic Acids | 2019 |
Bovine Milk Oligosaccharides with Sialyllactose Improves Cognition in Preterm Pigs.
Topics: Animals; Brain; Cattle; Cognition; Disease Models, Animal; Female; Lactose; Magnetic Resonance Imaging; Male; Maze Learning; Milk; Pregnancy; Premature Birth; Sialic Acids; Swine | 2019 |
6-sialyllactose ameliorates dihydrotestosterone-induced benign prostatic hyperplasia through suppressing VEGF-mediated angiogenesis.
Topics: Animals; Computational Biology; Culture Media, Conditioned; Dihydrotestosterone; Human Umbilical Vein Endothelial Cells; Humans; Lactose; Male; Neovascularization, Pathologic; Prostatic Hyperplasia; Rats; Sialic Acids; Vascular Endothelial Growth Factor A | 2019 |
CUPRA-ZYME: An Assay for Measuring Carbohydrate-Active Enzyme Activities, Pathways, and Substrate Specificities.
Topics: Carbohydrate Metabolism; Enzyme Assays; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactose; Neuraminidase; Sialic Acids; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2020 |
Antiviral potential of 3'-sialyllactose- and 6'-sialyllactose-conjugated dendritic polymers against human and avian influenza viruses.
Topics: Animals; Antiviral Agents; Birds; Chick Embryo; Dendrimers; Dogs; Hemagglutination Inhibition Tests; Humans; Influenza A virus; Lactose; Madin Darby Canine Kidney Cells; Oligosaccharides; Species Specificity | 2020 |
Topology-Matching Design of an Influenza-Neutralizing Spiky Nanoparticle-Based Inhibitor with a Dual Mode of Action.
Topics: Animals; Antiviral Agents; Dogs; Drug Design; Glycerol; Humans; Influenza A virus; Influenza, Human; Lactose; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Nanoparticles; Particle Size; Polymers; Sialic Acids; Surface Properties; Virus Replication; Zanamivir | 2020 |
Human Milk Oligosaccharide Supplementation Affects Intestinal Barrier Function and Microbial Composition in the Gastrointestinal Tract of Young Sprague Dawley Rats.
Topics: Animals; Biomarkers; Body Weight; Cecum; Dietary Supplements; Feces; Female; Gastrointestinal Microbiome; Gastrointestinal Tract; Interleukin-18; Lactose; Leptin; Male; Milk, Human; Oligosaccharides; Organ Size; Rats; Rats, Sprague-Dawley; RNA, Ribosomal, 16S; Sequence Analysis, RNA; Sialic Acids; Trisaccharides | 2020 |
Activation of the G-protein coupled receptor GPR35 by human milk oligosaccharides through different pathways.
Topics: Animals; Breast Feeding; Cattle; GTP-Binding Proteins; Host Microbial Interactions; Humans; Infant; Infant Formula; Lactose; Milk, Human; Oligosaccharides; Receptors, G-Protein-Coupled; Signal Transduction; Trisaccharides | 2020 |
Blends of Human Milk Oligosaccharides Confer Intestinal Epithelial Barrier Protection in Vitro.
Topics: Breast Feeding; Caco-2 Cells; Female; Fucose; HT29 Cells; Humans; Intestinal Mucosa; Lactose; Milk, Human; Oligosaccharides; Permeability; Sialic Acids | 2020 |
The structure and role of lactone intermediates in linkage-specific sialic acid derivatization reactions.
Topics: Catalysis; Lactones; Lactose; Magnetic Resonance Spectroscopy; Molecular Structure; Polysaccharides; Sialic Acids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2021 |
Simultaneous Quantification of 3'- and 6'-Sialyllactose in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Pharmacokinetic Study.
Topics: Administration, Oral; Animals; Carbohydrate Conformation; Chromatography, Liquid; Dose-Response Relationship, Drug; Lactose; Male; Oligosaccharides; Rats; Tandem Mass Spectrometry | 2021 |
Six Oligosaccharides' Variation in Breast Milk: A Study in South China from 0 to 400 Days Postpartum.
Topics: Adult; Breast Feeding; China; Female; Humans; Lactation; Lactose; Milk, Human; Mothers; Oligosaccharides; Postpartum Period; Trisaccharides; Young Adult | 2021 |
Towards Mapping of the Human Brain N-Glycome with Standardized Graphitic Carbon Chromatography.
Topics: Acetylgalactosamine; Brain; Brain Chemistry; Chromatography, Liquid; Fucose; Glycomics; Graphite; Humans; Lactose; Sialic Acids; Tandem Mass Spectrometry | 2022 |
Synthetic assembly of a series of glycopolymers having sialyl α2-3 lactose moieties connected with longer spacer arms.
Topics: Lactose; Polymers; Sialic Acids; Sugars | 2023 |
Synthesis of Neuraminidase-Resistant Sialyllactose Mimetics from N-Acyl Mannosamines using Metabolically Engineered Escherichia coli.
Topics: Escherichia coli; Lactose; Neuraminidase; Oligosaccharides; Sialyltransferases | 2023 |
Method for the Determination of 2'-Fucosyllactose (2'-FL), 3-Fucosyllactose (3-FL), 6'-Sialyllactose (6'-SL), 3'-Sialyllactose (3'-SL), Lacto-N-Tetraose (LNT), and Lacto-N-neoTetraose (LNnT) by High-Performance Anion-Exchange Chromatography With Pulsed Am
Topics: Adult; Chromatography; Humans; Infant; Lactose; Oligosaccharides | 2023 |
Isolation and characterization from porcine serum of a soluble sulfotransferase responsible for 6-O-sulfation of the galactose residue in 2'-fucosyllactose: implications in the synthesis of the ligand for L-selectin.
Topics: Animals; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Galactose; Humans; Lactose; Molecular Weight; Oligosaccharides; Phosphoadenosine Phosphosulfate; Substrate Specificity; Sulfotransferases; Swine; Trisaccharides | 1999 |
Receptor-binding properties of modern human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggs.
Topics: Agglutination Tests; Amino Sugars; Animals; Carbohydrate Sequence; Cell Line; Chick Embryo; Chlorocebus aethiops; Hemagglutinins, Viral; Humans; Influenza A virus; Lactose; Models, Molecular; Molecular Sequence Data; Receptors, Virus; Vero Cells; Virus Cultivation | 2003 |
Receptor-binding properties of swine influenza viruses isolated and propagated in MDCK cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Dogs; Hemagglutinins, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Kidney; Lactose; Models, Molecular; Receptors, Virus; Swine | 2005 |
Development of tetraphenylethylene-based fluorescent oligosaccharide probes for detection of influenza virus.
Topics: Biosensing Techniques; Ethylenes; Fluorescent Dyes; Humans; Lactose; Oligosaccharides; Orthomyxoviridae; Plant Lectins; Spectrometry, Fluorescence | 2010 |
Efficient synthesis of 6'-sialyllactose, 6,6'-disialyllactose, and 6'-KDO-lactose by metabolically engineered E. coli expressing a multifunctional sialyltransferase from the Photobacterium sp. JT-ISH-224.
Topics: Escherichia coli; Gene Expression; Genetic Engineering; Lactose; Magnetic Resonance Spectroscopy; Photobacterium; Sialyltransferases; Trisaccharides | 2010 |
Methylamidation for sialoglycomics by MALDI-MS: a facile derivatization strategy for both α2,3- and α2,6-linked sialic acids.
Topics: alpha-Fetoproteins; Animals; Carbohydrate Sequence; Cattle; Glycomics; Glycoproteins; Humans; Lactose; Methylamines; Mice; Molecular Sequence Data; Organophosphorus Compounds; Polysaccharides; Rats; Sialic Acids; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Flow cytometric analysis of lectin-oligosaccharide interactions by using fluorescent oligosaccharide probes.
Topics: Flow Cytometry; Fluorescent Dyes; Lactose; Lectins; Stilbenes; Trisaccharides | 2011 |
Sialic acid and sialyl-lactose glyco-conjugates: design, synthesis and binding assays to lectins and swine influenza H1N1 virus.
Topics: Biological Assay; Collodion; Glycoconjugates; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lactose; Molecular Mimicry; Molecular Structure; Oligopeptides; Plant Lectins; Protein Binding; Receptors, Virus; Sambucus nigra; Sialic Acids; Solid-Phase Synthesis Techniques; Virus Internalization | 2012 |
Novel efficient routes to indoxyl glycosides for monitoring glycosidase activities.
Topics: Fucose; Glycoside Hydrolases; Glycosides; Glycosylation; Indoles; Lactose; Molecular Structure; N-Acetylneuraminic Acid | 2013 |
Protein engineering of α2,3/2,6-sialyltransferase to improve the yield and productivity of in vitro sialyllactose synthesis.
Topics: beta-D-Galactoside alpha 2-6-Sialyltransferase; Cloning, Molecular; Lactose; Mutagenesis, Site-Directed; Mutant Proteins; Organisms, Genetically Modified; Pasteurella multocida; Photobacterium; Protein Engineering; Sequence Analysis, DNA; Sialyltransferases | 2014 |
Human milk oligosaccharides influence maturation of human intestinal Caco-2Bbe and HT-29 cell lines.
Topics: Apoptosis; Caco-2 Cells; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Enterocytes; Epithelial Cells; Gastrointestinal Tract; HT29 Cells; Humans; Intestinal Mucosa; Lactose; Milk, Human; Oligosaccharides; Trisaccharides | 2014 |
Fecal metabolomics of healthy breast-fed versus formula-fed infants before and during in vitro batch culture fermentation.
Topics: Batch Cell Culture Techniques; Breast Feeding; Feces; Fermentation; Galactose; Gas Chromatography-Mass Spectrometry; Gum Arabic; Humans; Infant; Infant Formula; Inulin; Lactose; Metabolomics; Oligosaccharides; Trisaccharides | 2014 |
Sialyllactose ameliorates myopathic phenotypes in symptomatic GNE myopathy model mice.
Topics: Aging; Amyloid beta-Peptides; Animals; Body Weight; Cells, Cultured; Creatine Kinase; Disease Models, Animal; Distal Myopathies; Enzyme-Linked Immunosorbent Assay; Hexosamines; Lactose; Mice; Muscle Contraction; Muscle, Skeletal; Mutation; Myoblasts; N-Acetylneuraminic Acid; Peptide Fragments; Phenotype | 2014 |
NMR analysis on the sialic acid-binding mechanism of an R-type lectin mutant by natural evolution-mimicry.
Topics: Galectins; Lactose; N-Acetylneuraminic Acid; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Domains | 2016 |
Temporal Change of the Content of 10 Oligosaccharides in the Milk of Chinese Urban Mothers.
Topics: Adult; Breast Feeding; China; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Delivery, Obstetric; Female; Humans; Infant; Infant, Newborn; Lactation; Lactose; Milk, Human; Mothers; Oligosaccharides; Trisaccharides; Urban Population | 2016 |
Major human milk oligosaccharides are absorbed into the systemic circulation after oral administration in rats.
Topics: Administration, Oral; Animals; Breast Feeding; Diet; Dietary Carbohydrates; Female; Intestinal Absorption; Intestines; Lactation; Lactose; Male; Milk, Human; Oligosaccharides; Rats, Sprague-Dawley; Trisaccharides | 2017 |
Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors.
Topics: Biosensing Techniques; Chromatography, Affinity; Electrochemical Techniques; Electrodes; Gold; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lactose; Limit of Detection; Quartz Crystal Microbalance Techniques | 2017 |
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus.
Topics: Adhesins, Bacterial; Animals; Catalytic Domain; Cell Line; Colon; Computational Biology; Crystallography, X-Ray; Glycoproteins; Goblet Cells; Humans; Lactose; Mice, Inbred C57BL; Mucins; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Neuraminidase; Protein Binding; Ruminococcus; Substrate Specificity; Symbiosis | 2017 |
Toxicological evaluation of 6'-sialyllactose (6'-SL) sodium salt.
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetulus; Female; Food Additives; Lactose; Male; Mice; Mutagenicity Tests; No-Observed-Adverse-Effect Level; Rats, Sprague-Dawley; Salmonella typhimurium; Salts; Toxicity Tests, Acute; Toxicity Tests, Subchronic | 2018 |
Breast milk oligosaccharides: effects of 2'-fucosyllactose and 6'-sialyllactose on the adhesion of
Topics: Bacterial Adhesion; Dietary Supplements; Escherichia coli; Humans; Infant Formula; Infant, Newborn; Lactose; Milk, Human; Salmonella; Trisaccharides | 2019 |
Two extracellular sialidases from Bifidobacterium bifidum promote the degradation of sialyl-oligosaccharides and support the growth of Bifidobacterium breve.
Topics: Bacterial Proteins; Bifidobacterium bifidum; Bifidobacterium breve; Culture Media; Female; Humans; Lactose; Milk, Human; N-Acetylneuraminic Acid; Neuraminidase; Oligosaccharides; Polysaccharides | 2018 |
The oligosaccharides 6'-sialyllactose, 2'-fucosyllactose or galactooligosaccharides do not directly modulate human dendritic cell differentiation or maturation.
Topics: Calcitriol; Cell Differentiation; Cells, Cultured; Cerebrospinal Fluid; Dendritic Cells; Humans; Interleukin-4; Lactose; Milk, Human; Oligosaccharides; Prebiotics; Transforming Growth Factor beta; Trisaccharides | 2018 |
Sialic Acid and Sialylated Oligosaccharide Supplementation during Lactation Improves Learning and Memory in Rats.
Topics: Animals; Behavior, Animal; Dietary Supplements; Female; Frontal Lobe; Lactation; Lactose; Learning; Long-Term Potentiation; Male; Memory; Milk; N-Acetylneuraminic Acid; Neural Cell Adhesion Molecule L1; Oligosaccharides; Rats; Rats, Sprague-Dawley; Sialic Acids | 2018 |
6'-Sialyllactose Ameliorates In Vivo and In Vitro Benign Prostatic Hyperplasia by Regulating the E2F1/pRb-AR Pathway.
Topics: Animals; E2F1 Transcription Factor; Lactose; Male; Prostatic Hyperplasia; Rats; Rats, Wistar; Receptors, Androgen; Retinoblastoma Protein; Signal Transduction; Testosterone | 2019 |
Quantitative analysis of 3'- and 6'-sialyllactose in human milk samples by HPLC-MS/MS: A validated method for the comparison of two consecutive lactation periods in the same woman.
Topics: Breast Feeding; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infant Formula; Lactation; Lactose; Milk, Human; Oligosaccharides; Tandem Mass Spectrometry; Trisaccharides | 2020 |
The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Line; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Ileum; Inflammation Mediators; Intestinal Mucosa; Lactose; Mice; Milk, Human; Molecular Docking Simulation; Signal Transduction; Sus scrofa; Toll-Like Receptor 4; Trisaccharides; Weight Loss | 2021 |
Insights image for "The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling."
Topics: Enterocolitis, Necrotizing; Humans; Infant, Newborn; Lactose; Milk, Human; Oligosaccharides; Toll-Like Receptor 4; Trisaccharides | 2021 |
Development and Validation of a Bioanalytical Method for 3'- and 6'-Sialyllactose in Minipig Liver and Kidney Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to Analysis of Tissue Distribution.
Topics: Animals; Biological Assay; Chromatography, Liquid; Kidney; Lactose; Linear Models; Liver; Reproducibility of Results; Swine; Swine, Miniature; Tandem Mass Spectrometry; Tissue Distribution | 2020 |
Development and validation of a bioanalytical method of analyzing 3'- and 6'-sialyllactose using liquid chromatography-tandem mass spectrometry in minipig plasma and its application in a pharmacokinetic study.
Topics: Animals; Chromatography, Liquid; Humans; Infant, Newborn; Lactose; Reproducibility of Results; Swine; Swine, Miniature; Tandem Mass Spectrometry | 2021 |
Inhibitory effects of 6'-sialyllactose on angiotensin II-induced proliferation, migration, and osteogenic switching in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Humans; Lactose; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Osteopontin; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases, 90-kDa; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1 | 2022 |