n-acetylneuraminic acid has been researched along with oseltamivir in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Bourguet, E; Figurska, S; Fra Czek, MM | 1 |
| Cairo, CW; Guo, T; Hunter, CD; Richards, MR | 1 |
| Bethell, RC; Blick, TJ; Colman, PM; Hart, GJ; McDonald, M; McKimm-Breschkin, JL; Sahasrabudhe, A; Varghese, JN | 1 |
| Bartmess, KC; McCullers, JA | 1 |
| Crouch, E; Hartshorn, KL; Hartshorn, M; Holmskov, U; Pemberton, L; Tornoe, I; van Eijk, M; White, MR | 1 |
| Goto, H; Hatakeyama, S; Kawakami, C; Kawaoka, Y; Kiso, M; Mitamura, K; Sakai-Tagawa, Y; Sugaya, N; Suzuki, Y | 1 |
| Chou, KC; Du, QS; Sun, H; Wei, DQ | 1 |
| Aruksakunwong, O; Decha, P; Hannongbua, S; Intharathep, P; Malaisree, M; Rungrotmongkol, T | 1 |
| Honda, A; Ishii, T; Yamazaki, Y | 1 |
| Belshe, RB; Fang, F; Gubareva, LV; Hedlund, M; Klimov, AI; Larson, JL; Moss, RB; Triana-Baltzer, GB; Wurtman, DF | 1 |
| Chuman, H; Harada, M; Hitaoka, S; Yoshida, T | 1 |
| Barrett, S; McKimm-Breschkin, JL; Mohr, PG; Schmidt, PM | 1 |
| Böhm, R; Dyason, JC; Garcia, JM; Haselhorst, T; Lai, JC; Madge, PD; Nicholls, JM; Peiris, JS; Rose, FJ; von Itzstein, M | 1 |
| Acharya, L; Behera, DK; Behera, PM; Dixit, A; Padhi, P | 1 |
| Gao, GF; Kiyota, H; Li, Q; Li, Y; Liu, Y; Qi, J; Sriwilaijaroen, N; Suzuki, Y; Tanaka, K; Vavricka, CJ; Wu, Y; Yan, J | 1 |
| Chi, HC; Hsiao, NW; Lin, CY; Shih, KC; Tang, CY; Zhou, J | 1 |
| Hou, M; Jansen, AJ; Ni, H; Peng, J; Zhao, HG | 1 |
| Alolga, RN; Cai, YY; Chen, QQ; Fan, Y; Huang, FQ; Li, H; Li, J; Li, P; Li, Y; Liu, B; Liu, JF; Ma, G; Qi, LW; Shen, JH; Wang, SL; Wang, XM; Wei, TT; Zhang, L; Zhao, DS; Zhu, W | 1 |
| Ikeda, K; Kato, D; Kurebayashi, Y; Minami, A; Otake, H; Otsubo, T; Suzuki, T; Takahashi, T; Tamoto, C; Yamazaki, M | 1 |
| Liu, GJ; Wang, B; Wang, S; Xing, GW; Yang, X; Zhang, Y | 1 |
| Fung, K; Nicholls, JM; Wong, HH | 1 |
| Aljohani, MA; Keil, JM; Rafn, GR; Sahebjam-Atabaki, R; Sun, XL; Turan, IM | 1 |
| Bieniek, KF; Fastenau, C; Hopp, SC; Odfalk, KF; Smith, S; Solano, L; Wickline, JL | 1 |
2 review(s) available for n-acetylneuraminic acid and oseltamivir
| Article | Year |
|---|---|
Human Neuraminidases: Structures and Stereoselective Inhibitors.
Topics: Amino Acid Sequence; Enzyme Inhibitors; Humans; Models, Molecular; Neuraminidase; Stereoisomerism; Structure-Activity Relationship | 2022 |
Sialidase Inhibitors with Different Mechanisms.
Topics: Antiviral Agents; Biological Products; Enzyme Inhibitors; Humans; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Sialic Acids; Zanamivir | 2022 |
21 other study(ies) available for n-acetylneuraminic acid and oseltamivir
| Article | Year |
|---|---|
Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity.
Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoenzymes; Kinetics; Molecular Dynamics Simulation; Neuraminidase; Sequence Alignment; Viral Proteins; Zanamivir | 2018 |
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors.
Topics: Acetamides; Adsorption; Animals; Binding Sites; Birds; Cell Line; Conserved Sequence; Dogs; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Heating; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Kinetics; Molecular Structure; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Phenotype; Pyrans; Sialic Acids; Substrate Specificity; Viral Plaque Assay; Virus Replication; Zanamivir | 1998 |
Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae.
Topics: Acetamides; Animals; Bacterial Adhesion; Cell Line; Disease Models, Animal; Enzyme Inhibitors; Epithelial Cells; Female; Lung; Mice; Mice, Inbred BALB C; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Pneumonia, Pneumococcal; Streptococcus pneumoniae | 2003 |
Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor.
Topics: Acetamides; Animals; Antiviral Agents; Chick Embryo; Chickens; CHO Cells; Cricetinae; Hemagglutinins; Humans; Influenza A virus; Influenza, Human; Mucins; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Receptors, Immunologic | 2005 |
Enhanced expression of an alpha2,6-linked sialic acid on MDCK cells improves isolation of human influenza viruses and evaluation of their sensitivity to a neuraminidase inhibitor.
Topics: Acetamides; Animals; Antiviral Agents; Cell Line; Dogs; Enzyme Inhibitors; Humans; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir | 2005 |
Insights from modeling the 3D structure of H5N1 influenza virus neuraminidase and its binding interactions with ligands.
Topics: Acetamides; Binding Sites; Computer Simulation; Enzyme Activation; Guanidines; Influenza A Virus, H5N1 Subtype; Models, Chemical; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Protein Binding; Protein Conformation; Pyrans; Sequence Analysis, Protein; Sialic Acids; Structure-Activity Relationship; Zanamivir | 2006 |
Understanding of known drug-target interactions in the catalytic pocket of neuraminidase subtype N1.
Topics: Acids, Carbocyclic; Algorithms; Antiviral Agents; Binding Sites; Catalysis; Computer Simulation; Cyclopentanes; Databases, Protein; Guanidines; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Influenza A Virus, H5N1 Subtype; Inhibitory Concentration 50; Ligands; Models, Molecular; Molecular Conformation; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Pressure; Protein Binding; Protein Structure, Secondary; Static Electricity; Temperature; Thermodynamics; Time Factors; Water; Zanamivir | 2008 |
The influence of oseltamivir carboxylate and oseltamivir on hemagglutinin inhibition and microneutralization test.
Topics: Animals; Cells, Cultured; Chickens; Erythrocytes; Female; Hemagglutination Inhibition Tests; Hemagglutinin Glycoproteins, Influenza Virus; Horses; Humans; Influenza A virus; Influenza, Human; Male; N-Acetylneuraminic Acid; Neutralization Tests; Oseltamivir | 2008 |
Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein.
Topics: Animals; Antiviral Agents; Binding Sites; Caco-2 Cells; Cell Proliferation; Dogs; Humans; Influenza, Human; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir; Recombinant Fusion Proteins; Zanamivir | 2009 |
Correlation analyses on binding affinity of sialic acid analogues with influenza virus neuraminidase-1 using ab initio MO calculations on their complex structures.
Topics: Animals; Antiviral Agents; Binding Sites; Humans; Influenza A virus; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Protein Binding | 2010 |
Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses.
Topics: Acids, Carbocyclic; Binding, Competitive; Cyclopentanes; Enzyme Assays; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Inhibitory Concentration 50; Kinetics; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir; Protein Binding; Substrate Specificity; Time Factors; Viral Proteins; Zanamivir | 2011 |
A secondary sialic acid binding site on influenza virus neuraminidase: fact or fiction?
Topics: Animals; Antiviral Agents; Binding Sites; Humans; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Nuclear Magnetic Resonance, Biomolecular; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir | 2012 |
In silico biology of H1N1: molecular modelling of novel receptors and docking studies of inhibitors to reveal new insight in flu treatment.
Topics: Antiviral Agents; Computational Biology; Enzyme Inhibitors; Humans; Hydrogen Bonding; Influenza A Virus, H1N1 Subtype; Influenza, Human; Molecular Docking Simulation; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Receptors, Virus | 2012 |
Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors.
Topics: Animals; Antiviral Agents; Biocatalysis; Conserved Sequence; Crystallography, X-Ray; Drug Resistance, Viral; Enzyme Inhibitors; Fluorescence; Humans; Kinetics; Madin Darby Canine Kidney Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Mutant Proteins; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir; Tyrosine; Virus Replication; Zanamivir | 2013 |
Development of 3D-QSAR combination approach for discovering and analysing neuraminidase inhibitors in silico.
Topics: Algorithms; Binding Sites; Computational Biology; Drug Design; Humans; Influenza, Human; Inhibitory Concentration 50; Least-Squares Analysis; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Quantitative Structure-Activity Relationship; Software; Technology, Pharmaceutical; Zanamivir | 2014 |
Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia.
Topics: Blood Platelets; Enzyme Inhibitors; Female; Humans; Influenza, Human; Male; Middle Aged; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Platelet Count; Retrospective Studies; Thrombocytopenia; Treatment Outcome | 2015 |
Functional Metabolomics Characterizes a Key Role for
Topics: Animals; Biomarkers; cdc42 GTP-Binding Protein; Cell Survival; Coronary Angiography; Coronary Artery Disease; Humans; Male; Metabolomics; Myocytes, Cardiac; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Protein Binding; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering | 2018 |
An easy, rapid, and sensitive method for detection of drug-resistant influenza virus by using a sialidase fluorescent imaging probe, BTP3-Neu5Ac.
Topics: Animals; Antiviral Agents; Biological Assay; Cell Line; Chlorocebus aethiops; Chromatography, Affinity; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Fluorescence; Fluorescent Dyes; Humans; Influenza, Human; Madin Darby Canine Kidney Cells; N-Acetylneuraminic Acid; Neuraminidase; Optical Imaging; Orthomyxoviridae; Oseltamivir; Ultraviolet Rays; Vero Cells | 2018 |
A tetravalent sialic acid-coated tetraphenylethene luminogen with aggregation-induced emission characteristics: design, synthesis and application for sialidase activity assay, high-throughput screening of sialidase inhibitors and diagnosis of bacterial va
Topics: Adult; Clostridium perfringens; Enzyme Inhibitors; Female; Fluorescence; Fluorescent Dyes; Fluorometry; High-Throughput Screening Assays; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Limit of Detection; Middle Aged; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Sialic Acids; Stilbenes; Vaginosis, Bacterial; Vibrio cholerae; Young Adult; Zanamivir | 2018 |
MDCK-B4GalNT2 cells disclose a α2,3-sialic acid requirement for the 2009 pandemic H1N1 A/California/04/2009 and NA aid entry of A/WSN/33.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; N-Acetylgalactosaminyltransferases; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Virus Attachment; Virus Internalization; Virus Replication | 2019 |
Increased α-2,6 sialic acid on microglia in amyloid pathology is resistant to oseltamivir.
Topics: Animals; Antiviral Agents; Mammals; Mice; Microglia; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Sialic Acids | 2023 |