n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime has been researched along with thiazoles in 5 studies
| Studies (n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime) | Trials (n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime) | Recent Studies (post-2010) (n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime) | Studies (thiazoles) | Trials (thiazoles) | Recent Studies (post-2010) (thiazoles) |
|---|---|---|---|---|---|
| 88 | 0 | 36 | 33,179 | 2,100 | 12,330 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davies, GJ; Dennis, RJ; Greig, IR; Macauley, MS; Stubbs, KA; Taylor, EJ; Vocadlo, DJ; Whitworth, GE | 1 |
| Alves, CN; Kanaan, N; Lameira, J; Martí, S; Moliner, V; Tuñón, I | 1 |
| Macauley, MS; Vocadlo, DJ | 1 |
| Alves, CN; de Alencar, NA; Lameira, J; Martí, S; Moliner, V; Silva, JR; Sousa, PR | 1 |
| Jin, FZ; Wu, MJ; Yang, Z; Yu, C; Zhao, DZ | 1 |
1 review(s) available for n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime and thiazoles
| Article | Year |
|---|---|
Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Catalytic Domain; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; N-Acetylglucosaminyltransferases; Oximes; Phenylcarbamates; Pyrazoles; Pyridines; Streptozocin; Thiazoles; Uridine Diphosphate N-Acetylglucosamine | 2010 |
4 other study(ies) available for n-acetylglucosaminono-1,5-lactone o-(phenylcarbamoyl)oxime and thiazoles
| Article | Year |
|---|---|
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Catalysis; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Glycosylation; Humans; Models, Molecular; Oximes; Phenylcarbamates; Substrate Specificity; Thermodynamics; Thiazoles | 2007 |
A quantum mechanics/molecular mechanics study of the protein-ligand interaction of two potent inhibitors of human O-GlcNAcase: PUGNAc and NAG-thiazoline.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Binding Sites; Biocatalysis; Drug Design; Enzyme Inhibitors; Humans; Ligands; Models, Molecular; Molecular Conformation; Oximes; Phenylcarbamates; Protein Binding; Protons; Quantum Theory; Static Electricity; Thermodynamics; Thiazoles | 2008 |
Computational analysis of human OGA structure in complex with PUGNAc and NAG-thiazoline derivatives.
Topics: Acetylglucosamine; Bacterial Proteins; Bacteroides; beta-N-Acetylhexosaminidases; Binding Sites; Clostridium perfringens; Crystallography, X-Ray; Humans; Isoenzymes; Kinetics; Ligands; Molecular Docking Simulation; Oximes; Phenylcarbamates; Protein Binding; Protein Conformation; Structural Homology, Protein; Thermodynamics; Thiazoles | 2012 |
A correlation between altered O-GlcNAcylation, migration and with changes in E-cadherin levels in ovarian cancer cells.
Topics: Acetylglucosamine; Antigens, CD; beta Catenin; Blotting, Western; Cadherins; Catenins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Delta Catenin; Female; Gene Silencing; Glycosylation; Humans; Multiprotein Complexes; N-Acetylglucosaminyltransferases; Ovarian Neoplasms; Oximes; Phenylcarbamates; Pyrans; RNA, Messenger; RNA, Small Interfering; Thiazoles; Transfection | 2013 |