n-acetylcolchinol and phenyliodonium

n-acetylcolchinol has been researched along with phenyliodonium* in 1 studies

Other Studies

1 other study(ies) available for n-acetylcolchinol and phenyliodonium

Article	Year
Synthesis of (S)-(-)-N-acetylcolchinol using intramolecular biaryl oxidative coupling. Organic & biomolecular chemistry, 2006, Jun-07, Volume: 4, Issue:11 An asymmetric synthesis of the tubulin polymerisation inhibitor (S)-(-)-N-acetylcolchinol is reported based on an intramolecular biaryl oxidative coupling of a 1,3-diarylpropyl acetamide intermediate using phenyliodonium bis(trifluoroacetate) as the final step. Three syntheses of the penultimate 1,3-diarylpropyl acetamide intermediate (S)-(-)-N-[1-[3-(tert-butyldimethylsilyloxy)phenyl)]-3-(3,4,5-trimethoxyphenyl)propyl] acetamide are described which differ in the means by which the stereogenic centre was introduced. Topics: Acetamides; Colchicine; Crystallography, X-Ray; Molecular Structure; Onium Compounds; Oxidation-Reduction; Stereoisomerism; Tubulin Modulators	2006

Article

Year

Synthesis of (S)-(-)-N-acetylcolchinol using intramolecular biaryl oxidative coupling.

Organic & biomolecular chemistry, 2006, Jun-07, Volume: 4, Issue:11

An asymmetric synthesis of the tubulin polymerisation inhibitor (S)-(-)-N-acetylcolchinol is reported based on an intramolecular biaryl oxidative coupling of a 1,3-diarylpropyl acetamide intermediate using phenyliodonium bis(trifluoroacetate) as the final step. Three syntheses of the penultimate 1,3-diarylpropyl acetamide intermediate (S)-(-)-N-[1-[3-(tert-butyldimethylsilyloxy)phenyl)]-3-(3,4,5-trimethoxyphenyl)propyl] acetamide are described which differ in the means by which the stereogenic centre was introduced.

Topics: Acetamides; Colchicine; Crystallography, X-Ray; Molecular Structure; Onium Compounds; Oxidation-Reduction; Stereoisomerism; Tubulin Modulators

2006