Page last updated: 2024-09-03

n-acetyl-4-s-cysteaminylphenol and cysteamine

n-acetyl-4-s-cysteaminylphenol has been researched along with cysteamine in 18 studies

Compound Research Comparison

Studies
(n-acetyl-4-s-cysteaminylphenol)
Trials
(n-acetyl-4-s-cysteaminylphenol)
Recent Studies (post-2010)
(n-acetyl-4-s-cysteaminylphenol)
Studies
(cysteamine)
Trials
(cysteamine)
Recent Studies (post-2010) (cysteamine)
19003,30760666

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (61.11)18.2507
2000's7 (38.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jimbow, K; Yamada, K1
Bloomer, WD; Prezioso, JA; Wang, N1
Bloomer, WD; Epperly, MW; Prezioso, JA; Wang, N1
Jimbow, K; Wong, M1
Ito, S; Jimbow, K; Miura, T1
Alena, F; Dixon, W; Jimbow, K; Thomas, P1
Iwashina, T; Jimbow, K; Wiebe, LI1
Alena, F; Gili, A; Iwashina, T; Jimbow, K1
Jimbow, K1
Jimbow, K; Minamitsuji, Y; Sugiyama, S; Toyofuku, K; Yamada, K1
Cao, H; Jimbow, K; Kishi, H; Ota, M; Singh, S; Thomas, PD; Yamashita, T1
Gili, A; Jimbow, K; Ota, M; Thomas, PD1
Bogdanov, A; Simonova, M; Wall, A; Weissleder, R1
Kelland, LR; Lant, NJ; McKeown, P; Robins, DJ; Rogers, PM1
Kelland, LR; Lant, NJ; McKeown, P; Robins, DJ; Rogers, PM; Timoney, MC1
Ferguson, J; Kelland, LR; Pearson, VC; Robins, DJ; Rogers, PM1
Ferguson, J; Kelland, LR; Robins, DJ; Rogers, PM1
Kelland, LR; Lant, N; Nicoll, K; Robertson, J; Robins, DJ; Rogers, PM1

Other Studies

18 other study(ies) available for n-acetyl-4-s-cysteaminylphenol and cysteamine

ArticleYear
Selective in vivo and in vitro incorporation and accumulation of phenolic thioether amine into malignant melanoma and identification of a (58 kD) binding glycoprotein.
    Melanoma research, 1992, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents; Autoradiography; Chromatography, Affinity; Cysteamine; Cysteine; Electrophoresis, Polyacrylamide Gel; Female; Germ-Free Life; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phenols; Radioligand Assay; RNA Cap-Binding Proteins; RNA-Binding Proteins; Substrate Specificity; Tumor Cells, Cultured

1992
Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Agents; Cell Division; Cell-Free System; Cysteamine; DNA; Humans; Kinetics; Leucovorin; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Tetrazolium Salts; Theophylline; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured

1992
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
    Cancer letters, 1992, Mar-31, Volume: 63, Issue:1

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cysteamine; Drug Synergism; Humans; Melanoma; Methionine Sulfoximine; Monophenol Monooxygenase; Phenols; Theophylline; Time Factors; Tumor Cells, Cultured

1992
Selective cytotoxicity of N-acetyl-4-S-cysteaminylphenol on follicular melanocytes of black mice.
    The British journal of dermatology, 1991, Volume: 124, Issue:1

    Topics: Animals; Antineoplastic Agents; Cysteamine; Hair; Melanocytes; Mice; Mice, Inbred C57BL; Microscopy, Electron; Phenols; Pigmentation

1991
The in vivo antimelanoma effect of 4-S-cysteaminylphenol and its n-acetyl derivative.
    International journal of cancer, 1990, Nov-15, Volume: 46, Issue:5

    Topics: Animals; Antineoplastic Agents; Carbidopa; Cell Division; Cysteamine; Cysteine; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Kinetics; Levodopa; Melanoma, Experimental; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Neoplasm Transplantation; Phenols; Substrate Specificity

1990
Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles.
    The Journal of investigative dermatology, 1995, Volume: 104, Issue:5

    Topics: Animals; Cell Death; Cysteamine; Dose-Response Relationship, Drug; Glutathione; Hair; Hair Color; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Phenols; Pigmentation; Skin

1995
The synthesis of N-acetyl-4-S-cysteaminyl [U-14C]phenol as a basis for the development of an antimelanoma and melanoma-radioimaging agent.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 1994, Volume: 45, Issue:6

    Topics: Acetylation; Antineoplastic Agents; Carbon Radioisotopes; Cysteamine; Isotope Labeling; Melanoma; Models, Chemical; Phenols; Radionuclide Imaging

1994
Selective in vivo accumulation of N-acetyl-4-S-cysteaminylphenol in B16F10 murine melanoma and enhancement of its in vitro and in vivo antimelanoma effect by combination of buthionine sulfoximine.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Animals; Autoradiography; Buthionine Sulfoximine; Cysteamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione; Lung Neoplasms; Melanoma, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Phenols

1994
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1998
Sulfur containing tyrosine analogs can cause selective melanocytotoxicity involving tyrosinase-mediated apoptosis.
    The journal of investigative dermatology. Symposium proceedings, 1999, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; COS Cells; Cystamine; Cysteamine; Female; Hair Color; Hair Follicle; Humans; Kinetics; Melanocytes; Mice; Mice, Inbred C57BL; Microscopy, Electron; Monophenol Monooxygenase; Oxidative Stress; Phenols; Pregnancy; Transfection

1999
Selective incorporation and specific cytocidal effect as the cellular basis for the antimelanoma action of sulphur containing tyrosine analogs.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cystamine; Cysteamine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; HeLa Cells; Humans; Melanoma; Mice; Monophenol Monooxygenase; Phenols

1999
Comparison of in vitro cytotoxicity of N-acetyl and N-propionyl derivatives of phenolic thioether amines in melanoma and neuroblastoma cells and the relationship to tyrosinase and tyrosine hydroxylase enzyme activity.
    Melanoma research, 2000, Volume: 10, Issue:1

    Topics: Amides; Antineoplastic Agents; Cell Division; Cystamine; Cysteamine; Growth Inhibitors; HeLa Cells; Humans; Melanoma; Monophenol Monooxygenase; Neuroblastoma; Phenols; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2000
Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells.
    Cancer research, 2000, Dec-01, Volume: 60, Issue:23

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biotransformation; Cell Division; Cell Line; Cysteamine; Fibrosarcoma; Gliosarcoma; Humans; Kidney; Melanins; Monophenol Monooxygenase; Mutation; Phenols; Prodrugs; Propanols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured

2000
Synthesis and antimelanoma activity of analogues of N-acetyl-4-S-cysteaminylphenol.
    Anti-cancer drug design, 2000, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Cell Division; Cysteamine; Growth Inhibitors; Humans; Melanoma; Phenols; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Synthesis and anti-melanoma activity of analogues of N-acetyl-4-S-cysteaminylphenol substituted with two methyl groups alpha to the nitrogen.
    Anti-cancer drug design, 2001, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Cysteamine; Drug Screening Assays, Antitumor; Female; Humans; Indicators and Reagents; Melanoma, Experimental; Ovarian Neoplasms; Phenols; Structure-Activity Relationship; Tumor Cells, Cultured

2001
Synthesis and antimelanoma activity of tertiary amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2003, Volume: 13, Issue:11

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cysteamine; Humans; Melanoma; Phenols; Protein Structure, Tertiary

2003
Synthesis and antimelanoma activity of sterically congested tertiary amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2005, Volume: 15, Issue:2

    Topics: Agaricales; Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteamine; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Melanins; Melanoma; Models, Chemical; Monophenol Monooxygenase; Nitrogen; Oxygen; Phenols; Stereoisomerism; Sulfides; Time Factors; Ultraviolet Rays

2005
Synthesis and antimelanoma activity of reversed amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2006, Volume: 16, Issue:2

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cysteamine; Humans; Melanoma; Molecular Structure; Phenols; Structure-Activity Relationship

2006