n-2-hexyl-n-methylpropargylamine has been researched along with selegiline in 7 studies
| Studies (n-2-hexyl-n-methylpropargylamine) | Trials (n-2-hexyl-n-methylpropargylamine) | Recent Studies (post-2010) (n-2-hexyl-n-methylpropargylamine) | Studies (selegiline) | Trials (selegiline) | Recent Studies (post-2010) (selegiline) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 2,575 | 319 | 394 |
| Protein | Taxonomy | n-2-hexyl-n-methylpropargylamine (IC50) | selegiline (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 0.0055 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.0039 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.798 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.376 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.2127 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.9046 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 1.4408 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.0067 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 0.1001 | |
| Type-1 angiotensin II receptor | Sus scrofa (pig) | 0.048 | |
| Alpha-synuclein | Homo sapiens (human) | 0.27 | |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | 1 | |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, PH; Zhang, X; Zuo, DM | 1 |
| Yu, PH; Zhang, X | 1 |
| Boulton, AA; Davis, BA; Yu, PH; Zhang, X; Zuo, DM | 1 |
| Lai, CT; Yu, PH | 1 |
| Boulton, AA; Davis, BA; Durden, DA; Dyck, LE; Juorio, AV; Li, XM; Paterson, IA; Yu, PH | 1 |
| Paterson, IA; Tatton, WG | 1 |
| Boulton, AA; Paterson, IA; Warrington, RC; Zhang, D | 1 |
7 other study(ies) available for n-2-hexyl-n-methylpropargylamine and selegiline
| Article | Year |
|---|---|
Neuroprotection by R(-)-deprenyl and N-2-hexyl-N-methylpropargylamine on DSP-4, a neurotoxin, induced degeneration of noradrenergic neurons in the rat locus coeruleus.
Topics: Adrenergic Agents; Animals; Benzylamines; Locus Coeruleus; Male; Nerve Degeneration; Neurons; Norepinephrine; Propylamines; Rats; Rats, Wistar; Selegiline | 1995 |
Depletion of NOS activity in the rat dentate gyrus neurons by DSP-4 and protection by deprenyl.
Topics: Animals; Benzylamines; Dentate Gyrus; Enzyme Inhibitors; Histocytochemistry; Male; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Propylamines; Rats; Rats, Wistar; Selegiline | 1995 |
Immunohistochemical evidence of neuroprotection by R(-)-deprenyl and N-(2-hexyl)-N-methylpropargylamine on DSP-4-induced degeneration of rat brain noradrenergic axons and terminals.
Topics: Animals; Axons; Benzylamines; Immunohistochemistry; Male; Monoamine Oxidase Inhibitors; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Neurotoxins; Norepinephrine; Propylamines; Rats; Rats, Wistar; Reference Values; Selegiline; Sensitivity and Specificity | 1996 |
R(-)-deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Dopamine; Drug Synergism; Humans; Levodopa; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pargyline; Propylamines; Reactive Oxygen Species; Selegiline; Tumor Cells, Cultured | 1997 |
Aliphatic N-methylpropargylamines: monoamine oxidase-B inhibitors and antiapoptotic drugs.
Topics: Animals; Apoptosis; Brain; Gene Expression Regulation, Enzymologic; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Propylamines; Selegiline; Structure-Activity Relationship; Tissue Distribution; Tyrosine 3-Monooxygenase | 1998 |
Antiapoptotic actions of monoamine oxidase B inhibitors.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebellum; Isoenzymes; Monoamine Oxidase Inhibitors; Neurons; PC12 Cells; Propylamines; Rats; Rats, Wistar; Selegiline | 1998 |
R-deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cells, Cultured; Cerebellum; Cytarabine; Kinetics; Mitochondria; Neurons; Potassium; Propylamines; Rats; Rats, Wistar; Selegiline | 1998 |