n 0861 has been researched along with adenosine in 17 studies
| Studies (n 0861) | Trials (n 0861) | Recent Studies (post-2010) (n 0861) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 20 | 1 | 0 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | n 0861 (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (88.24) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hurt, CM; Pelleg, A | 1 |
| Martin, PL | 1 |
| Barrett, RJ; Droppleman, DA; Wright, KF | 1 |
| Belardinelli, L; Shryock, JC; Travagli, HC | 1 |
| Barrett, RJ; Beller, GA; Glover, DK; Ruiz, M; Sansoy, V | 1 |
| Iskandrian, AS | 1 |
| Marala, RB; Mustafa, SJ | 1 |
| Martin, PL; May, JM | 1 |
| Barrett, R; Belardinelli, L; Rush, W; Sidi, A; Wesley, R | 1 |
| Barrett, RJ; Wright, KF | 1 |
| Porzio, D; Sadeghi, M; Wesley, RC | 1 |
| Hurt, CM; Pelleg, A; Tong, H; Wang, L; Xu, J | 1 |
| Martin, PL; McKenna, DG; Potts, AA; Sykes, AM | 1 |
| Belardinelli, L; Bertolet, BD; Franco, EA; Hill, JA; Kerensky, RA; Nichols, WW | 1 |
| Giannella, E; Levi, R; Mochmann, HC | 1 |
| Auchampach, JA; Bhattacharya, S; Black, RG; Bolli, R; Kodani, E; Takano, H; Tang, XL; Yang, Z | 1 |
| Fahim, M; Mustafa, SJ | 1 |
17 other study(ies) available for n 0861 and adenosine
| Article | Year |
|---|---|
Effects of N6-endonorbornan-2-yl-9-methyladenine, N0861, on negative chronotropic and vasodilatory actions of adenosine in the canine heart in vivo.
Topics: Adenine; Adenosine; Animals; Coronary Vessels; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Vasodilation | 1992 |
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1992 |
N-0861 selectively antagonizes adenosine A1 receptors in vivo.
Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1992 |
Evaluation of N-0861, (+-)-N6-endonorbornan-2-yl-9-methyladenine, as an A1 subtype-selective adenosine receptor antagonist in the guinea pig isolated heart.
Topics: Adenine; Adenosine; Animals; Carrier Proteins; Coronary Vessels; Guinea Pigs; Heart; Heart Conduction System; Hypoxia; In Vitro Techniques; Membrane Proteins; Norbornanes; Nucleoside Transport Proteins; Perfusion; Receptors, Purinergic; Vasodilation | 1992 |
Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Exercise Test; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists; Radionuclide Imaging; Thallium Radioisotopes; Vasodilation | 1995 |
New directions in pharmacologic stress imaging.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Norbornanes; Purinergic P1 Receptor Antagonists | 1995 |
Adenosine analogues prevent phorbol ester-induced PKC depletion in porcine coronary artery via A1 receptor.
Topics: Adenine; Adenosine; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Phenethylamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Swine | 1995 |
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines | 1994 |
Cardiovascular effects of a non-xanthine-selective antagonist of the A1 adenosine receptor in the anaesthetised pig: pharmacological and therapeutic implications.
Topics: Adenine; Adenosine; Anesthesia; Animals; Atropine; Cardiovascular System; Coronary Vessels; Female; Heart; Male; Norbornanes; Propranolol; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Swine; Theophylline | 1994 |
A selective adenosine A1 receptor antagonist attenuates renal dysfunction during controlled hypotension with adenosine in rats.
Topics: Adenine; Adenosine; Animals; Blood Pressure; Hypotension, Controlled; Kidney; Male; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 1994 |
Effect of selective A1 adenosine receptor antagonism of postdefibrillation cardiovascular depression: evidence for an antiadrenergic role of endogenous adenosine.
Topics: Adenine; Adenosine; Animals; Electric Countershock; Female; Heart; Male; Myocardial Contraction; Norbornanes; Propranolol; Purinergic Antagonists; Receptors, Adrenergic; Swine | 1993 |
Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo.
Topics: Adenine; Adenosine; Animals; Female; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Block; Male; Myocardial Ischemia; Norbornanes; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Virulence Factors, Bordetella | 1993 |
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Drug Antagonism; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Muscle Relaxation; Norbornanes; Purinergic Antagonists; Stereoisomerism; Vasodilator Agents | 1993 |
Selective attenuation by N-0861 (N6-endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptor-mediated effects in humans.
Topics: Adenine; Adenosine; Aged; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Humans; Male; Middle Aged; Norbornanes; Pain; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 1996 |
Ischemic preconditioning prevents the impairment of hypoxic coronary vasodilatation caused by ischemia/reperfusion: role of adenosine A1/A3 and bradykinin B2 receptor activation.
Topics: Adenine; Adenosine; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Guinea Pigs; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Receptor, Adenosine A3; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Purinergic P1; Vasodilation | 1997 |
A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms.
Topics: Adenine; Adenosine; Animals; Binding, Competitive; Cell Line; Consciousness; Decanoic Acids; Humans; Hydroxy Acids; Iodine Radioisotopes; Ischemic Preconditioning, Myocardial; Membranes; Myocardial Infarction; Nitroarginine; Norbornanes; Phenethylamines; Rabbits; Radioligand Assay; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2001 |
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Hypertension; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norbornanes; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Theobromine; Vasodilation | 2001 |