Compounds > n'-nitrosonornicotine
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n'-nitrosonornicotine and warfarin

n'-nitrosonornicotine has been researched along with warfarin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friesen, MJ; Murphy, SE; Patten, CJ; Smith, TJ; Tynes, RE; Yang, CS1
Murphy, SE; Patten, CJ; Peterson, LA1
Michno, N; Murphy, SE; Schlicht, KE; Scott, EE; Smith, BD1
Berg, JZ; Murphy, SE; Schlicht, KE1

Other Studies

4 other study(ies) available for n'-nitrosonornicotine and warfarin

ArticleYear
Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; CHO Cells; Chromatography, High Pressure Liquid; Coumarins; Cricetinae; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Nitrosamines; Nitroso Compounds

1997
Evidence for metabolic activation of N'-nitrosonornicotine and N-nitrosobenzylmethylamine by a rat nasal coumarin hydroxylase.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Inhibitors; Hydroxylation; Kinetics; Male; Methoxsalen; Microsomes; Mixed Function Oxygenases; Nasal Mucosa; Nicotiana; Nitrosamines; Nitroso Compounds; Plants, Toxic; Rats; Rats, Inbred F344

1998
Functional characterization of CYP2A13 polymorphisms.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:12

    Topics: Amino Acid Sequence; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Carcinogens; Coumarins; Humans; Hydroxylation; Nitrosamines; Polymorphism, Genetic; Sequence Deletion

2007
Effect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Catalytic Domain; Chromatography, High Pressure Liquid; Coumarins; Models, Molecular; Mutagenesis, Site-Directed; Nicotiana; Nitrosamines; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry

2009