Page last updated: 2024-09-03

n',n''-diacetylspermine and spermine

n',n''-diacetylspermine has been researched along with spermine in 48 studies

Compound Research Comparison

Studies
(n',n''-diacetylspermine)
Trials
(n',n''-diacetylspermine)
Recent Studies (post-2010)
(n',n''-diacetylspermine)
Studies
(spermine)
Trials
(spermine)
Recent Studies (post-2010) (spermine)
502206,154251,056

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.17)18.7374
1990's7 (14.58)18.2507
2000's17 (35.42)29.6817
2010's17 (35.42)24.3611
2020's5 (10.42)2.80

Authors

AuthorsStudies
Govaerts, LC; Monnens, LA; Muskiet, FA; Theeuwes, A; van den Berg, GA1
Libby, PR; Porter, CW1
Bolkenius, FN; Seiler, N1
Hiramatsu, K; Hoshino, M; Iwasaki, K; Kamei, S; Kawakita, M; Kinoshita, K; Sugimoto, M3
Bai, G; Fujiwara, K; Furukawa, K; Kanetake, H; Kitagawa, T; Masuyama, Y; Tanimori, H1
Hiramatsu, K; Iwasaki, K; Kamei, S; Kawakita, M; Miura, H1
Fujiwara, K; Kaminishi, Y; Kanetake, H; Kitagawa, T; Nomata, K; Tsuru, D; Yabuuchi, M1
Hiramatsu, K; Kawakita, M; Kobayashi, M; Samejima, K1
Hamaoki, M; Hiramatsu, K; Kawakita, M; Nagata, A; Suzuki, S1
Hiramatsu, K; Kawakita, M; Sugimoto, M; Takahashi, K; Toi, M1
Matsuoka, A; Sakamoto, T1
Hiramatsu, K; Kawakita, M; Matsumoto, H; Miyamoto, H; Mori, T; Takahashi, K; Tamamori, Y; Yamaguchi, T1
Hamasaki, N; Kawakita, M; Nagano, M; Tanaka, M; Torada, N; Yamaguchi, K1
Hiramatsu, K; Kariyone, K; Kawaguchi, M; Kawakita, M; Mori, T; Sasaki, Y; Shinoura, N; Takahashi, K; Tamamori, Y; Tanaka, T; Yamada, R1
Anai, M; Enjoji, M; Hamasaki, N; Kaku, T; Kato, M; Kawakita, M; Tanaka, M; Yamaguchi, K1
Hiramatsu, K; Imajo, M; Kawaguchi, M; Kawakita, M; Matsumoto, H; Miyamoto, H; Mori, T; Takahashi, K; Tamamori, Y; Tanaka, C; Tanaka, S; Toi, M; Yamaguchi, T1
Hamasaki, N; Kawakita, M; Konomi, H; Nakamura, M; Shirahane, K; Tanaka, M; Torata, N; Yamaguchi, K1
Hiramatsu, K; Kawakita, M2
Hiramatsu, K; Kawakita, M; Miki, T1
Hamaoki, M; Nagata, A1
Enjoji, M; Kotoh, K; Nakamuta, M1
Fiala, R; Hanulova, Z; Humenanska, V; Karpisek, M; Solichova, P; Stejskal, D; Vrtal, R1
Furue, M; Shibata, S; Tokunaga, S1
Hirata, K; Kameshima, H; Kuribayashi, K; Nishidate, T; Ohe, Y; Tsuji, N; Umemori, Y; Watanabe, N1
Hiramatsu, K; Kawakita, M; Takahashi, K1
Doi, Y; Hiramatsu, K; Kawakita, M; Kosaka, M; Yanagiya, M1
Hiramatsu, K; Horiguchi, S; Iwasaki, K; Kawakita, M; Kobayashi, M; Koizumi, K; Kuwata, G; Moriya, SS; Samejima, K; Takahashi, K1
Fujie, N; Hiramatsu, K; Iwasaki, K; Kawaikta, M; Moriya, SS; Saitoh, F; Sakaguchi, K; Sakaguchi, M; Takahama, E; Takahashi, K1
Hiramatsu, K; Kawakita, M; Kimura, E; Matsumoto, K; Moriya, SS1
Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L1
Higuchi, K; Katano, M; Kato, M; Matsumoto, K; Motoshita, J; Onishi, H; Tsuruta, N1
Hiramatsu, K; Horio, H; Kawakita, M; Sakaguchi, K; Takahashi, Y1
Casero, RA; Cho, K; Dejea, CM; Edler, D; Felding, BH; Goetz, L; Hechenbleikner, EM; Hoang, LT; Ivanisevic, J; Johnson, CH; Pardoll, DM; Patti, GJ; Santidrian, AF; Sears, CL; Siuzdak, G; Uritboonthai, W; White, JR; Wick, EC1
Barnett, M; DeFelice, B; Feng, Z; Fiehn, O; Gandara, D; Goodman, G; Hanash, S; Miyamoto, S; Taguchi, A; Wikoff, WR; Zhao, Y1
Hiramatsu, K; Horio, H; Kawakita, M; Moriya, S; Sakaguchi, K; Takahashi, K; Takahashi, Y1
Dejea, CM; Sears, CL1
Cao, Y; Gao, Y; Guo, S; Hu, L; Hu, X; Jing, F; Jing, Y; Wang, Y; Xu, M; Zhang, Y; Zhu, Z1
Häkkinen, MR; Keinänen, TA; Kumpulainen, PS; Lehtimäki, T; Mäenpää, JU; Niemi, RJ; Oksala, NK; Roine, AN; Vepsäläinen, JJ1
Häkkinen, MR; Kiviniemi, MS; Kumpulainen, PS; Lehtimäki, T; Oksala, NK; Rantanen, TK; Roine, AN; Venäläinen, MK; Vepsäläinen, JJ1
Huang, Q; Huang, Y; Wang, K; Yang, J; Yang, K; Zhao, G1
Arun, B; Capello, M; Creighton, CJ; Dennison, JB; Disis, ML; Do, KA; Fahrmann, JF; Fleury, A; Hanash, S; Irajizad, E; Katayama, H; Long, JP; Murage, E; Peterson, C; Tripathi, S; Vykoukal, J; Wang, P; Yu, CY1
Aita, Y; Asakage, M; Goto, H; Komatsu, H; Nezu, N; Shimizu, H; Sugimoto, M; Tomita, A; Tsubota, K; Umazume, K; Usui, Y; Wakita, R1
Andersson, C; Benson, MD; Chen, ZZ; Clish, CB; Correa, A; Cruz, DE; Dailey, L; Gao, Y; Gerszten, RE; Hall, ME; Katz, DH; Ngo, D; Peterson, B; Robbins, JM; Shen, C; Shi, X; Tahir, UA; Vasan, RS; Wang, TJ; Wilson, JG; Zhao, T1
Amano, H; Hinoki, A; Hiramatsu, K; Kawakita, M; Kawamura, M; Kuwatsuka, Y; Makita, S; Nakagawa, Y; Okamoto, M; Shirota, C; Sumida, W; Tainaka, T; Takimoto, A; Uchida, H; Yasui, A; Yokota, K1
Chiu, PK; Ng, CF; Tse, RT; Wong, CY1

Reviews

7 review(s) available for n',n''-diacetylspermine and spermine

ArticleYear
[Clinical usefulness of urinary diacetylpolyamines as novel tumor markers].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Prognosis; Prostatic Neoplasms; Spermidine; Spermine

2004
[Urinary diacetylspermine: its analysis and performance as a novel tumor marker].
    Rinsho byori. The Japanese journal of clinical pathology, 2005, Volume: 53, Issue:2

    Topics: Biomarkers, Tumor; Brain Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Humans; Neoplasms; Spermine

2005
[Urine diacetylspermine as a novel tumor marker].
    Rinsho byori. The Japanese journal of clinical pathology, 2005, Volume: 53, Issue:2

    Topics: Biliary Tract Neoplasms; Biomarkers, Tumor; Enzyme-Linked Immunosorbent Assay; Female; Genital Neoplasms, Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Sensitivity and Specificity; Spermine

2005
[Urinary diacetylspermine].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Neoplasms; Reference Values; Specimen Handling; Spermine

2005
[Factors affecting the increase of urinary diacetylspermine levels : a study in patients with liver diseases].
    Rinsho byori. The Japanese journal of clinical pathology, 2006, Volume: 54, Issue:2

    Topics: Biomarkers, Tumor; Diagnosis, Differential; False Positive Reactions; Fatty Liver; Glucocorticoids; Hepatitis, Autoimmune; Hepatitis, Viral, Human; Humans; Liver Diseases; Neoplasms; Spermine

2006
Diacetylated derivatives of spermine and spermidine as novel promising tumor markers.
    Journal of biochemistry, 2006, Volume: 139, Issue:3

    Topics: Animals; Biomarkers, Tumor; Humans; Neoplasms; Spermidine; Spermine

2006
The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies.
    International journal of molecular sciences, 2022, Jan-23, Volume: 23, Issue:3

    Topics: Acetylation; Biomarkers, Tumor; Humans; Neoplasms; Polyamines; Prognosis; Spermidine; Spermine

2022

Trials

2 trial(s) available for n',n''-diacetylspermine and spermine

ArticleYear
Excretion of N(1), N(12)-diacetylspermine in the urine of healthy individuals.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 4

    Topics: Adult; Biomarkers, Tumor; Creatinine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Sex Characteristics; Spermine

2014
Metabolism links bacterial biofilms and colon carcinogenesis.
    Cell metabolism, 2015, Jun-02, Volume: 21, Issue:6

    Topics: Bacteria; Bacterial Physiological Phenomena; Biofilms; Colonic Neoplasms; Female; Humans; Male; Spermine

2015

Other Studies

39 other study(ies) available for n',n''-diacetylspermine and spermine

ArticleYear
Urinary polyamine and metabolite excretion by children with Zellweger's syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Nov-15, Volume: 192, Issue:1

    Topics: Amino Acids, Diamino; Child, Preschool; Female; Humans; Hydrolysis; Infant; Infant, Newborn; Polyamines; Spermidine; Spermine; Zellweger Syndrome

1990
Separation of two isozymes of polyamine oxidase from murine L1210 leukemia cells.
    Biochemical and biophysical research communications, 1987, Apr-14, Volume: 144, Issue:1

    Topics: Animals; Isoenzymes; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Molecular Weight; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermine; Substrate Specificity

1987
Acetylderivatives as intermediates in polyamine catabolism.
    The International journal of biochemistry, 1981, Volume: 13, Issue:3

    Topics: Animals; Kinetics; Liver; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Spermidine; Spermine; Substrate Specificity

1981
Significance of urinary N1,N8-diacetylspermidine and N1,N12-diacetylspermine as indicators of neoplastic diseases.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:5

    Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Spermidine; Spermine

1995
Determination of amounts of polyamines excreted in urine: demonstration of N1,N8-diacetylspermidine and N1,N12-diacetylspermine as components commonly occurring in normal human urine.
    Journal of biochemistry, 1995, Volume: 117, Issue:1

    Topics: Biogenic Polyamines; Biomarkers; Chemical Fractionation; Humans; Reference Values; Spermidine; Spermine

1995
Determination of urinary acetylpolyamines by a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA).
    Journal of biochemistry, 1995, Volume: 118, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Cross Reactions; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Reference Values; Sensitivity and Specificity; Spermine; Succinimides

1995
Diagnostic and prognostic usefulness of N1,N8-diacetylspermidine and N1,N12-diacetylspermine in urine as novel markers of malignancy.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:10

    Topics: Adult; Biomarkers, Tumor; Female; Humans; Male; Middle Aged; Neoplasms; Prognosis; Spermidine; Spermine; Time Factors

1997
Development of a sensitive and accurate enzyme-linked immunosorbent assay (ELISA) system that can replace HPLC analysis for the determination of N1,N12-diacetylspermine in human urine.
    Journal of biochemistry, 1998, Volume: 124, Issue:1

    Topics: Amino Acid Sequence; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Immune Sera; Molecular Sequence Data; Reproducibility of Results; Sensitivity and Specificity; Spermine

1998
Preparation of monoclonal antibodies against N-(gamma-maleimidobutyryloxy)succinimide (GMBS)-conjugated acetylspermine, and development of an enzyme-linked immunosorbent assay (ELISA) for N1,N12-diacetylspermine.
    Journal of biochemistry, 1998, Volume: 124, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Mice, Inbred BALB C; Sensitivity and Specificity; Spermine; Succinimides

1998
Mass spectrometric separation and determination of N1,N12-diacetylspermine in the urine of cancer patients.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:3

    Topics: Enzyme-Linked Immunosorbent Assay; Humans; Neoplasms; Reference Standards; Spermine

2002
Two enzyme-linked immunosorbent assay (ELISA) systems for N1,N8-diacetylspermidine and N1,N12-diacetylspermine using monoclonal antibodies.
    Journal of biochemistry, 2002, Volume: 132, Issue:5

    Topics: Antibodies, Monoclonal; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Humans; Spermidine; Spermine

2002
[Establishment of an ELISA system of N1,N12-diacetylspermine in human urine].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Reagent Kits, Diagnostic; Sensitivity and Specificity; Spermidine; Spermine

2004
[The significance of urine di-acetyl spermine level as a cancer marker for colorectal cancer].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Biomarkers, Tumor; Carcinoembryonic Antigen; Colorectal Neoplasms; Humans; Neoplasm Staging; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Spermine

2004
[Urine diacetylspermine as a novel tumor marker for pancreatobiliary carcinomas].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biliary Tract Neoplasms; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms; Pancreatic Neoplasms; Sensitivity and Specificity; Spermidine; Spermine

2004
N(1),N(12)-Diacetylspermine as a sensitive and specific novel marker for early- and late-stage colorectal and breast cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-15, Volume: 11, Issue:8

    Topics: Adult; Biomarkers, Tumor; Breast Neoplasms; CA-19-9 Antigen; Carcinoembryonic Antigen; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Mucin-1; Neoplasm Staging; Sensitivity and Specificity; Spermine

2005
Urine diacetylspermine as a novel tumour maker for pancreatobiliary carcinomas.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biliary Tract Neoplasms; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; Female; Humans; Middle Aged; Pancreatic Neoplasms; Sensitivity and Specificity; Spermine

2005
Interaction of N1,N12-diacetylspermine with polyamine transport systems of polarized porcine renal cell line LLC-PK1.
    Journal of biochemistry, 2005, Volume: 138, Issue:4

    Topics: Animals; Biological Transport; Biomarkers, Tumor; Cell Polarity; LLC-PK1 Cells; Polyamines; Spermine; Swine

2005
Host macrophages produce diacetylspermine related with tumorigenesis.
    Cancer letters, 2006, Nov-08, Volume: 243, Issue:1

    Topics: Animals; Cell Line, Tumor; Coculture Techniques; Dose-Response Relationship, Drug; Female; Glucose; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Putrescine; Spermidine; Spermine; Spleen; Thioglycolates

2006
Evaluation of urine N1,N12-Diacetylspermine as potential tumor marker for urinary bladder cancer.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2006, Volume: 150, Issue:2

    Topics: Biomarkers, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Middle Aged; Spermine; Urinary Bladder Neoplasms

2006
[Estimation of urinary diacetylspermine in Yusho patients].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2007, Volume: 98, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Food Contamination; Humans; Japan; Male; Middle Aged; Oryza; Oxidative Stress; Plant Oils; Polychlorinated Biphenyls; Spermine

2007
Evaluating the utility of N1,N12-diacetylspermine and N1,N8-diacetylspermidine in urine as tumor markers for breast and colorectal cancers.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Dec-14, Volume: 411, Issue:23-24

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Carcinoembryonic Antigen; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Mucin-1; Reference Values; Spermine; Time Factors

2010
[Urinary diacetylspermine].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Adult; Biomarkers, Tumor; Female; Humans; Male; Middle Aged; Spermine

2010
Determination of N¹,N¹²-diacetylspermine in urine: a novel tumor marker.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 720

    Topics: Animals; Biochemistry; Biomarkers, Tumor; Carcinoembryonic Antigen; Cattle; Chromatography, High Pressure Liquid; Colloids; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Gold; Humans; Peptides; Sensitivity and Specificity; Specimen Handling; Spermine

2011
Increase of N1, N12-diacetylspermine in tissues from colorectal cancer and its liver metastasis.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Female; Humans; Liver Neoplasms; Male; Mass Spectrometry; Middle Aged; Neoplasm Staging; Precancerous Conditions; Spermine

2013
Construction of an immunochromatographic determination system for N¹,N¹²-diacetylspermine.
    Journal of clinical laboratory analysis, 2014, Volume: 28, Issue:6

    Topics: Biomarkers, Tumor; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Gold Colloid; Humans; Metal Nanoparticles; Spermine

2014
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
    Nature, 2014, Apr-10, Volume: 508, Issue:7495

    Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Diet; Energy Metabolism; Fatty Liver; Gene Knockdown Techniques; Glucose Intolerance; Glucose Transporter Type 4; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; S-Adenosylmethionine; Sirtuin 1; Spermine; Thinness

2014
Prognostic significance of urine N1, N12-diacetylspermine in patients with non-small cell lung cancer.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Spermine; Survival Rate

2014
Significant correlation between urinary N(1), N(12)-diacetylspermine and tumor invasiveness in patients with clinical stage IA non-small cell lung cancer.
    BMC cancer, 2015, Feb-18, Volume: 15

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Creatinine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Spermine

2015
Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Nov-20, Volume: 33, Issue:33

    Topics: Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Chromatography, Liquid; Disease-Free Survival; Early Detection of Cancer; Female; Humans; Lung Neoplasms; Male; Mass Spectrometry; Middle Aged; Prognosis; Protein Precursors; Pulmonary Surfactant-Associated Proteins; Risk Assessment; ROC Curve; Sensitivity and Specificity; Smoking; Spermine; Statistics, Nonparametric; Survival Analysis

2015
Urinary N1, N12-diacetylspermine is a non-invasive marker for the diagnosis and prognosis of non-small-cell lung cancer.
    British journal of cancer, 2015, Nov-17, Volume: 113, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Early Detection of Cancer; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Regression Analysis; Spermine

2015
Do biofilms confer a pro-carcinogenic state?
    Gut microbes, 2016, Volume: 7, Issue:1

    Topics: Bacterial Toxins; Bacteroides fragilis; Biofilms; Colonic Neoplasms; Escherichia coli; Fusobacterium nucleatum; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Metalloendopeptidases; Peptides; Polyketides; Spermine

2016
Identification of arginine and its "Downstream" molecules as potential markers of breast cancer.
    IUBMB life, 2016, Volume: 68, Issue:10

    Topics: Adolescent; Adult; Aged; Arginine; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Female; Humans; Middle Aged; Ornithine; ROC Curve; Spermine; Young Adult

2016
Urinary Polyamines as Biomarkers for Ovarian Cancer.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2017, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Biogenic Polyamines; Biomarkers, Tumor; Case-Control Studies; Chromatography, Liquid; Female; Humans; Middle Aged; Neoplasm Grading; Neoplasm Staging; Ovarian Neoplasms; Postmenopause; Prospective Studies; Spermine; Tandem Mass Spectrometry

2017
Altered Polyamine Profiles in Colorectal Cancer.
    Anticancer research, 2018, Volume: 38, Issue:6

    Topics: Adult; Aged; Biomarkers, Tumor; Chromatography, Liquid; Colorectal Neoplasms; Early Diagnosis; Female; Humans; Male; Middle Aged; Polyamines; Prospective Studies; Sensitivity and Specificity; Spermine; Tandem Mass Spectrometry

2018
Gene polymorphisms of SFTPB rs7316, rs9752 and PAOX rs1046175 affect the diagnostic value of plasma Pro-SFTPB and DAS in Chinese Han non-small-cell lung cancer patients.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:9

    Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Case-Control Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Prognosis; Protein Precursors; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Proteins; Risk Factors; Spermine

2019
Association Between Plasma Diacetylspermine and Tumor Spermine Synthase With Outcome in Triple-Negative Breast Cancer.
    Journal of the National Cancer Institute, 2020, 06-01, Volume: 112, Issue:6

    Topics: Animals; Chromatography, Liquid; Female; Gene Expression; Humans; Mice; Mice, Transgenic; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Spermine; Spermine Synthase; Tandem Mass Spectrometry; Triple Negative Breast Neoplasms

2020
Differential Tissue Metabolic Signatures in IgG4-Related Ophthalmic Disease and Orbital Mucosa-Associated Lymphoid Tissue Lymphoma.
    Investigative ophthalmology & visual science, 2021, 01-04, Volume: 62, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Female; Glycolates; Humans; Immunoglobulin G; Lymphoma, B-Cell, Marginal Zone; Malates; Male; Mass Spectrometry; Metabolome; Metabolomics; Middle Aged; Orbital Diseases; Orbital Neoplasms; Paraproteinemias; Principal Component Analysis; Retrospective Studies; ROC Curve; Spermine

2021
Metabolomic Profiles and Heart Failure Risk in Black Adults: Insights From the Jackson Heart Study.
    Circulation. Heart failure, 2021, Volume: 14, Issue:1

    Topics: Adult; Aged; Black or African American; Case-Control Studies; Collagen; Coronary Disease; Effect Modifier, Epidemiologic; Female; Heart Disease Risk Factors; Heart Failure; Homoarginine; Humans; Hypertrophy, Left Ventricular; Incidence; Longitudinal Studies; Male; Metabolomics; Middle Aged; Nitric Oxide; Orotic Acid; Polyamines; Proline; Proportional Hazards Models; Pyrimidines; Risk; RNA Processing, Post-Transcriptional; Spermine; Stroke Volume; Uridine; White People

2021
Urinary N
    Pediatric surgery international, 2021, Volume: 37, Issue:12

    Topics: Adult; Aged; Biomarkers, Tumor; Case-Control Studies; Child; Humans; Neoplasms; Spermine

2021