Page last updated: 2024-09-03

n',n''-diacetylspermine and spermidine

n',n''-diacetylspermine has been researched along with spermidine in 12 studies

Compound Research Comparison

Studies
(n',n''-diacetylspermine)
Trials
(n',n''-diacetylspermine)
Recent Studies (post-2010)
(n',n''-diacetylspermine)
Studies
(spermidine)
Trials
(spermidine)
Recent Studies (post-2010) (spermidine)
502205,643281,281

Protein Interaction Comparison

ProteinTaxonomyn',n''-diacetylspermine (IC50)spermidine (IC50)
Pyruvate kinase PKMHomo sapiens (human)1.41

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's4 (33.33)18.2507
2000's6 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Govaerts, LC; Monnens, LA; Muskiet, FA; Theeuwes, A; van den Berg, GA1
Bolkenius, FN; Seiler, N1
Hiramatsu, K; Hoshino, M; Iwasaki, K; Kamei, S; Kawakita, M; Kinoshita, K; Sugimoto, M3
Hamaoki, M; Hiramatsu, K; Kawakita, M; Nagata, A; Suzuki, S1
Hiramatsu, K; Kawakita, M; Sugimoto, M; Takahashi, K; Toi, M1
Matsuoka, A; Sakamoto, T1
Hamasaki, N; Kawakita, M; Nagano, M; Tanaka, M; Torada, N; Yamaguchi, K1
Hamaoki, M; Nagata, A1
Hiramatsu, K; Kawakita, M1
Chiu, PK; Ng, CF; Tse, RT; Wong, CY1

Reviews

3 review(s) available for n',n''-diacetylspermine and spermidine

ArticleYear
[Clinical usefulness of urinary diacetylpolyamines as novel tumor markers].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Prognosis; Prostatic Neoplasms; Spermidine; Spermine

2004
Diacetylated derivatives of spermine and spermidine as novel promising tumor markers.
    Journal of biochemistry, 2006, Volume: 139, Issue:3

    Topics: Animals; Biomarkers, Tumor; Humans; Neoplasms; Spermidine; Spermine

2006
The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies.
    International journal of molecular sciences, 2022, Jan-23, Volume: 23, Issue:3

    Topics: Acetylation; Biomarkers, Tumor; Humans; Neoplasms; Polyamines; Prognosis; Spermidine; Spermine

2022

Other Studies

9 other study(ies) available for n',n''-diacetylspermine and spermidine

ArticleYear
Urinary polyamine and metabolite excretion by children with Zellweger's syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Nov-15, Volume: 192, Issue:1

    Topics: Amino Acids, Diamino; Child, Preschool; Female; Humans; Hydrolysis; Infant; Infant, Newborn; Polyamines; Spermidine; Spermine; Zellweger Syndrome

1990
Acetylderivatives as intermediates in polyamine catabolism.
    The International journal of biochemistry, 1981, Volume: 13, Issue:3

    Topics: Animals; Kinetics; Liver; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Spermidine; Spermine; Substrate Specificity

1981
Significance of urinary N1,N8-diacetylspermidine and N1,N12-diacetylspermine as indicators of neoplastic diseases.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:5

    Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Spermidine; Spermine

1995
Determination of amounts of polyamines excreted in urine: demonstration of N1,N8-diacetylspermidine and N1,N12-diacetylspermine as components commonly occurring in normal human urine.
    Journal of biochemistry, 1995, Volume: 117, Issue:1

    Topics: Biogenic Polyamines; Biomarkers; Chemical Fractionation; Humans; Reference Values; Spermidine; Spermine

1995
Diagnostic and prognostic usefulness of N1,N8-diacetylspermidine and N1,N12-diacetylspermine in urine as novel markers of malignancy.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:10

    Topics: Adult; Biomarkers, Tumor; Female; Humans; Male; Middle Aged; Neoplasms; Prognosis; Spermidine; Spermine; Time Factors

1997
Two enzyme-linked immunosorbent assay (ELISA) systems for N1,N8-diacetylspermidine and N1,N12-diacetylspermine using monoclonal antibodies.
    Journal of biochemistry, 2002, Volume: 132, Issue:5

    Topics: Antibodies, Monoclonal; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Humans; Spermidine; Spermine

2002
[Establishment of an ELISA system of N1,N12-diacetylspermine in human urine].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Reagent Kits, Diagnostic; Sensitivity and Specificity; Spermidine; Spermine

2004
[Urine diacetylspermine as a novel tumor marker for pancreatobiliary carcinomas].
    Rinsho byori. The Japanese journal of clinical pathology, 2004, Volume: 52, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biliary Tract Neoplasms; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms; Pancreatic Neoplasms; Sensitivity and Specificity; Spermidine; Spermine

2004
Host macrophages produce diacetylspermine related with tumorigenesis.
    Cancer letters, 2006, Nov-08, Volume: 243, Issue:1

    Topics: Animals; Cell Line, Tumor; Coculture Techniques; Dose-Response Relationship, Drug; Female; Glucose; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Putrescine; Spermidine; Spermine; Spleen; Thioglycolates

2006