n'-methyl-4-pyridone-3-carboxamide has been researched along with niacinamide in 21 studies
| Studies (n'-methyl-4-pyridone-3-carboxamide) | Trials (n'-methyl-4-pyridone-3-carboxamide) | Recent Studies (post-2010) (n'-methyl-4-pyridone-3-carboxamide) | Studies (niacinamide) | Trials (niacinamide) | Recent Studies (post-2010) (niacinamide) |
|---|---|---|---|---|---|
| 22 | 2 | 3 | 13,381 | 1,097 | 5,797 |
| Protein | Taxonomy | n'-methyl-4-pyridone-3-carboxamide (IC50) | niacinamide (IC50) |
|---|---|---|---|
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | 1000 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 3.3 | |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 2.9 | |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | 8.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bender, DA; Njagi, EN | 1 |
| Kakehi, H; Matsuo, H; Shibata, K | 1 |
| Matsuo, H; Shibata, K | 1 |
| Iwai, K; Kawada, T; Shibata, K | 1 |
| Jenden, DJ; Jope, RS; Kang-Lee, YA; McKee, RW; Swendseid, ME; Wright, SM | 1 |
| Brown, RR; Harper, AE; Linkswiler, H; Patterson, JI | 1 |
| Kondo, T; Shibata, K; Shimada, H | 1 |
| Shibata, K; Toda, S | 1 |
| Kondo, T; Miki, A; Shibata, K | 1 |
| Bachki, A; Banerjee, K; Leyland-Jones, B; Wong, P | 1 |
| Fukuwatari, T; Ishikawa, A; Kodama, N; Nishimuta, M; Okamoto, H; Shibata, K; Yoshitake, Y | 1 |
| ABELSON, D; BOYLE, A; SELIGSON, H | 1 |
| ABELSON, D; BOYLE, A | 1 |
| Kitamura, S; Ohta, S; Shimomiya, K; Sugihara, K; Tayama, Y; Yoshimoto, D | 1 |
| Kowalik, K; Rutkowski, B; Rutkowski, P; Slominska, EM; Smolenski, RT; Swierczynski, J; Szolkiewicz, M | 1 |
| Aleksandrowicz, E; Renke, M; Rutkowski, B; Rutkowski, P; Smolenski, RT; Swierczynski, J; Szołkiewicz, M; Słominska, EM; Wisterowicz, K; Wołyniec, W | 1 |
| Adams, MH; Cefali, EA; González, MA; Leu, JH; Menon, RM; Tolbert, DS | 1 |
| Rutkowski, B; Rutkowski, P; Slominska, EM; Smoleński, RT; Swierczyński, J; Szolkiewicz, M; Wołyniec, W | 1 |
| Fukuwatari, T; Morita, N; Shibata, K; Shibata, Y | 1 |
| Fukuwatari, T; Shibata, K; Suzuki, C | 1 |
| Fukuwatari, T; Maeta, A; Sano, M; Shibata, K | 1 |
2 trial(s) available for n'-methyl-4-pyridone-3-carboxamide and niacinamide
| Article | Year |
|---|---|
Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide.
Topics: Adult; Chromatography, High Pressure Liquid; Circadian Rhythm; Cold Temperature; Cross-Over Studies; Darkness; Female; Humans; Kinetics; Mental Processes; Niacin; Niacinamide; Stress, Physiological; Tryptophan | 2003 |
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
Topics: Adult; Cross-Over Studies; Delayed-Action Preparations; Humans; Male; Middle Aged; Niacin; Niacinamide; Nicotinic Acids; Vitamins | 2007 |
19 other study(ies) available for n'-methyl-4-pyridone-3-carboxamide and niacinamide
| Article | Year |
|---|---|
Tryptophan metabolism in mice infected with Schistosoma mansoni.
Topics: Animals; Cells, Cultured; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Schistosomiasis mansoni; Serotonin; Tryptophan; Xanthurenates | 1991 |
Niacin catabolism in rodents.
Topics: Animals; Cricetinae; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred ICR; Niacin; Niacinamide; Nicotinic Acids; Species Specificity | 1990 |
Correlation between niacin equivalent intake and urinary excretion of its metabolites, N'-methylnicotinamide, N'-methyl-2-pyridone-5-carboxamide, and N'-methyl-4-pyridone-3-carboxamide, in humans consuming a self-selected food.
Topics: Adult; Chromatography, High Pressure Liquid; Diet; Energy Intake; Female; Humans; Microchemistry; Niacin; Niacinamide; Statistics as Topic | 1989 |
Simultaneous micro-determination of nicotinamide and its major metabolites, N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-3-carboxamide, by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Humans; Male; Niacinamide; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1988 |
Metabolic effects of nicotinamide administration in rats.
Topics: Animals; Blood Glucose; Choline; Creatinine; Cystathionine gamma-Lyase; Lipid Metabolism; Liver; Male; Methyltransferases; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains | 1983 |
Excretion of tryptophan-niacin metabolites by young men: effects of tryptophan, leucine, and vitamin B6 intakes.
Topics: Adult; Dose-Response Relationship, Drug; Humans; Leucine; Male; Niacinamide; Nicotinic Acids; Nitrogen; Pyridoxine; Quinolinic Acids; Tryptophan | 1980 |
Effects of feeding tryptophan-limiting diets on the conversion ratio of tryptophan to niacin in rats.
Topics: Amino Acids; Animals; Caseins; Diet; Eating; Gelatin; Liver; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Zein | 1996 |
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Hormones; Hydroxyindoleacetic Acid; Liver; Male; Niacin; Niacinamide; Pellagra; Pregnancy; Rats; Rats, Wistar; Serotonin; Testosterone; Tryptophan | 1997 |
Increased conversion ratio of tryptophan to niacin in severe food restriction.
Topics: Animals; Food Deprivation; Kynurenic Acid; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 1998 |
Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.
Topics: Chromatography, High Pressure Liquid; Coffee; Humans; Niacinamide; Nicotinic Acids | 2002 |
Identification of N'-methyl-4-pyridone-3-carboxamide in human plasma.
Topics: Niacinamide; Pyridines | 1963 |
Photochemistry of a nicotinamide metabolite, N'-methyl-4-pyridone-3-carboxamide.
Topics: Niacin; Niacinamide; Pyridines; Pyridones | 1963 |
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.
Topics: Aldehyde Oxidase; Animals; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Species Specificity | 2006 |
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Kidney Failure, Chronic; Male; NAD; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 2006 |
Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.
Topics: Adult; Aged; Biomarkers; Creatinine; Female; Glutathione; Humans; Kidney Failure, Chronic; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Niacinamide; Oxidative Stress | 2007 |
Nicotinamide metabolites accumulate in the tissues of uremic rats.
Topics: Animals; Disease Models, Animal; Male; Nephrectomy; Niacinamide; Pyridones; Rats; Rats, Wistar; Reference Values; Ultrafiltration; Uremia | 2008 |
Enzymes that control the conversion of L-tryptophan-nicotinamide and the urinary excretion ratio (N(1)-methyl-2-pyridone-5-carboxamide + N(1)-methyl-4-pyridone-3-carboxamide)/N(1)-methylnicotinamide in mice.
Topics: Animals; Body Weight; Eating; Enzymes; Male; Mice; NAD; Niacinamide; Pyridones; Quinolinic Acid; Tryptophan | 2013 |
Pharmacological doses of nicotinic acid and nicotinamide are independently metabolized in rats.
Topics: Animals; Diet; Drug Interactions; Male; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Rats, Wistar | 2014 |
Simultaneous measurement of nicotinamide and its catabolites, nicotinamide N-oxide, N(1)-methyl-2-pyridone-5-carboxamide, and N(1)-methyl-4-pyridone-3-carboxamide, in mice urine.
Topics: Animals; Mice; Niacinamide; Pyridones; Time Factors; Urinalysis | 2014 |