Page last updated: 2024-09-04

n'-methyl-4-pyridone-3-carboxamide and niacin

n'-methyl-4-pyridone-3-carboxamide has been researched along with niacin in 9 studies

Compound Research Comparison

Studies
(n'-methyl-4-pyridone-3-carboxamide)
Trials
(n'-methyl-4-pyridone-3-carboxamide)
Recent Studies (post-2010)
(n'-methyl-4-pyridone-3-carboxamide)
Studies
(niacin)
Trials
(niacin)
Recent Studies (post-2010) (niacin)
222311,9744621,488

Protein Interaction Comparison

ProteinTaxonomyn'-methyl-4-pyridone-3-carboxamide (IC50)niacin (IC50)
Cholesteryl ester transfer proteinHomo sapiens (human)0.14
Cytochrome P450 2C9 Homo sapiens (human)0.14
Hydroxycarboxylic acid receptor 2Homo sapiens (human)0.1726
Hydroxycarboxylic acid receptor 2Mus musculus (house mouse)0.14

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kakehi, H; Matsuo, H; Shibata, K1
Matsuo, H; Shibata, K1
Kondo, T; Shibata, K; Shimada, H1
Shibata, K; Toda, S1
Kondo, T; Miki, A; Shibata, K1
Fukuwatari, T; Ishikawa, A; Kodama, N; Nishimuta, M; Okamoto, H; Shibata, K; Yoshitake, Y1
ABELSON, D; BOYLE, A1
Adams, MH; Cefali, EA; González, MA; Leu, JH; Menon, RM; Tolbert, DS1
Fukuwatari, T; Shibata, K; Suzuki, C1

Trials

2 trial(s) available for n'-methyl-4-pyridone-3-carboxamide and niacin

ArticleYear
Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Circadian Rhythm; Cold Temperature; Cross-Over Studies; Darkness; Female; Humans; Kinetics; Mental Processes; Niacin; Niacinamide; Stress, Physiological; Tryptophan

2003
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:8

    Topics: Adult; Cross-Over Studies; Delayed-Action Preparations; Humans; Male; Middle Aged; Niacin; Niacinamide; Nicotinic Acids; Vitamins

2007

Other Studies

7 other study(ies) available for n'-methyl-4-pyridone-3-carboxamide and niacin

ArticleYear
Niacin catabolism in rodents.
    Journal of nutritional science and vitaminology, 1990, Volume: 36, Issue:2

    Topics: Animals; Cricetinae; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred ICR; Niacin; Niacinamide; Nicotinic Acids; Species Specificity

1990
Correlation between niacin equivalent intake and urinary excretion of its metabolites, N'-methylnicotinamide, N'-methyl-2-pyridone-5-carboxamide, and N'-methyl-4-pyridone-3-carboxamide, in humans consuming a self-selected food.
    The American journal of clinical nutrition, 1989, Volume: 50, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Diet; Energy Intake; Female; Humans; Microchemistry; Niacin; Niacinamide; Statistics as Topic

1989
Effects of feeding tryptophan-limiting diets on the conversion ratio of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:10

    Topics: Amino Acids; Animals; Caseins; Diet; Eating; Gelatin; Liver; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Zein

1996
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:7

    Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Hormones; Hydroxyindoleacetic Acid; Liver; Male; Niacin; Niacinamide; Pellagra; Pregnancy; Rats; Rats, Wistar; Serotonin; Testosterone; Tryptophan

1997
Increased conversion ratio of tryptophan to niacin in severe food restriction.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:3

    Topics: Animals; Food Deprivation; Kynurenic Acid; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Xanthurenates

1998
Photochemistry of a nicotinamide metabolite, N'-methyl-4-pyridone-3-carboxamide.
    Nature, 1963, Feb-02, Volume: 197

    Topics: Niacin; Niacinamide; Pyridines; Pyridones

1963
Pharmacological doses of nicotinic acid and nicotinamide are independently metabolized in rats.
    Journal of nutritional science and vitaminology, 2014, Volume: 60, Issue:2

    Topics: Animals; Diet; Drug Interactions; Male; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Rats, Wistar

2014